Follow-up evaluation of patients with Graves' disease treated by subtotal thyroidectomy and risk factor analysis for post-operative thyroid dysfunction.

abstract：:Reduced cardiac mass and performances are present in GH deficiency and are counteracted by rhGH replacement. GH and IGF-I possess specific myocardial receptors and have been reported able to exert an acute inotropic effect. Synthetic GH secretagogues (GHS) possess specific pituitary and hypothalamic but even myocardia...

journal_title：Journal of endocrinological investigation

authors： Bisi G,Podio V,Valetto MR,Broglio F,Bertuccio G,Del Rio G,Arvat E,Boghen MF,Deghenghi R,Muccioli G,Ong H,Ghigo E

更新日期：1999-04-01 00:00:00

abstract：:Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the use of somatostatin and its derivatives in ophthalmology based on current understanding of its action in the eye and summarizes previously published controlled s...

journal_title：Journal of endocrinological investigation

authors： Missotten T,Baarsma GS,Kuijpers RW,van den Born LI,van der Loos T,Croxen R,Hofland LJ,van Hagen PM

更新日期：2005-01-01 00:00:00

abstract：:The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

journal_title：Journal of endocrinological investigation

authors： Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

更新日期：1989-01-01 00:00:00

abstract：:A 57-year-old man with pituitary metastasis from renal cell carcinoma is reported. He underwent right nephrectomy and total pancreatectomy for renal cell carcinoma and its pancreatic metastasis, respectively. Imaging studies showed an intrasellar mass lesion. The examination revealed panhypopituitarism, diabetes insip...

journal_title：Journal of endocrinological investigation

authors： Koshiyama H,Ohgaki K,Hida S,Takasu K,Yumitori K,Shimatsu A,Koh T

更新日期：1992-10-01 00:00:00

abstract：:We report here on the isolation and repertoire characterization of a Graves' thyroid T cell population which, unlike most Graves' thyroid T cell isolates reported before, was rich in CD4-CD8- T cells (16%, all TcR gamma delta+) and CD8+ T cells (75%) [TcR alpha beta+ (59%) and TcR gamma delta+ (16%)]. Only 7% of the i...

journal_title：Journal of endocrinological investigation

authors： Santamaria P,Lewis C,Barbosa JJ

更新日期：1993-12-01 00:00:00

abstract：:Formation of connective tissue is an essential step in the process of wound healing. After menopause an atrophy of connective tissues in skin, bone, and reproductive organs takes place. Using a dead-space wound healing model we measured collagen synthesis and deposition, and cell replication in the granulation tissue ...

journal_title：Journal of endocrinological investigation

authors： Gniadecki R,Wyrwas B,Kabala A,Matecka J

更新日期：1996-04-01 00:00:00

abstract：:We treated a 10 6/12 year old prepubertal male with hypophosphatemic rickets, who was growing poorly despite appropriate treatment with calcitriol and phosphate, with exogenous growth hormone (for an initial trial period of 4 months, followed by 14 months of continuous treatment at a dose of 4 IU three times weekly) e...

journal_title：Journal of endocrinological investigation

authors： Lanes R,Harrison HE

更新日期：1990-11-01 00:00:00

abstract：:A study of the effects of salmon calcitonin (sCT) infusion on blood sugar and serum insulin levels under basal conditions and after intravenous glucose load in normal subjects is reported. Under basal conditions, a 30 min infusion of sCT at approximately a rate of 1 U/min produced a highly significant increase in the ...

journal_title：Journal of endocrinological investigation

authors： Petralito A,Lunetta M,Liuzzo A,Fiore CE,Heynen G

更新日期：1979-04-01 00:00:00

abstract：:Homocysteine (HCY) is a sulfur-containing amino acid involved in two metabolic pathways, catalized by cystathionine-B-synthase and methionine synthase, depending on vitamin (vit) B6, B12, and folate levels and enzymatic activity of methylenetetrahydrofolate. High HCY levels (HHCY) are associated with cardiovascular (C...

journal_title：Journal of endocrinological investigation

authors： Petramala L,Acca M,Francucci CM,D'Erasmo E

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:In the mountainous areas of Azerbaijan the schoolchildren suffer from severe Iodine Deficiency (ID) with median Urinary iodine excretion (UIE) 36 mcg/l and prevalence of goiter 99% (estimated by US). In a population of 293,000 schoolchildren aged 8-14 y.o. we administered capsules containing 190 mg of iodized...

journal_title：Journal of endocrinological investigation

authors： Markou KB,Georgopoulos NA,Makri M,Vlasopoulou B,Anastasiou E,Vagenakis GA,Kouloubi K,Theodosopoulos N,Lazarou N,Veizis A,Sakellaropoulos G,Vagenakis AG

更新日期：2003-01-01 00:00:00

abstract：:Circulating TSH bioactivity may vary in several clinical and experimental conditions. Since the reliability of the current methods for the measurement of TSH bioactivity is limited, a new bioassay based on cAMP accumulation in Chinese Hamster Ovary cells transfected with recombinant human TSH receptor (CHO-R) was set ...

journal_title：Journal of endocrinological investigation

authors： Persani L,Tonacchera M,Beck-Peccoz P,Vitti P,Mammoli C,Chiovato L,Elisei R,Faglia G,Ludgate M,Vassart G

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Subclinical thyroid dysfunctions may cause cognitive deficits and mood disorders. Chronic TSH-suppressive therapy with L-T(4) causing subclinical hyperthyroidism has been widely used in treatment of patients with thyroid differentiated carcinoma. The impact of this therapy on cognitive functions and mood hav...

journal_title：Journal of endocrinological investigation

authors： Jaracz J,Kucharska A,Rajewska-Rager A,Lacka K

更新日期：2012-09-01 00:00:00

abstract：:A dialyzable, thermostable inhibitor of normal thyroid peroxidase (TPO), with UV absorption maximum at 250-260 nm, was found in the digitonized, washed particulate fraction of two dyshormonogenetic goiters. No intrinsic TPO iodide-oxidation activity was detectable in either of these goiters, and their TPO iodination a...

journal_title：Journal of endocrinological investigation

authors： Rosenthal D,Carvalho-Guimarães DP,Knobel M,Medeiros-Neto GA

更新日期：1990-12-01 00:00:00

abstract：:The changes occurring in the levels of circulating thyroid microsomal antibody (M-Ab) and antithyroglobulin antibody (Tg-Ab) during antithyroid drug therapy were studied in 32 patients receiving methimazole for Graves' disease. M-Ab was determined by competitive binding radioassay and Tg-Ab by a sandwich radiometric m...

journal_title：Journal of endocrinological investigation

authors： Marcocci C,Chiovato L,Mariotti S,Pinchera A

更新日期：1982-01-01 00:00:00

abstract：:The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate...

journal_title：Journal of endocrinological investigation

authors： Basaria S,McCarthy EF,Belzberg AJ,Ball DW

更新日期：2000-09-01 00:00:00

abstract：:Hexarelin (Hex) is a synthetic hexapeptide with potent GH-releasing activity in both animals and men. Aim of this study was to evaluate the GH response to a maximal dose of Hex and GH-releasing hormone (GHRH) in a group of patients with Prader-Willi syndrome (PWS). Seven patients (4 boys and 3 girls, age 2.4-14.2 yr) ...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Raguso G,Palmiotto T,Faedda A,Gurreri F,Neri G,Deghenghi R,Loche S

更新日期：1998-09-01 00:00:00

abstract：:The effect of exogenous prednisone on serum thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations was investigated in four patients with non-functioning thyroid glands receiving T4 replacement therapy. Orally administered prednisone, in a dose of 20 mg each day for nine days, resulted in a signif...

journal_title：Journal of endocrinological investigation

authors： Jensen J,Nolan G,Jubiz W

更新日期：1978-04-01 00:00:00

abstract：:During diabetic ketoacidosis, in 17 adult patients, significant decreases in serum TBG and total T4 levels were observed, without significant alteration of the T4 to TBG binding property. In addition, serum free T4 (FT4) was moderately elevated and the TSH response to TRH was markedly blunted. No correlation, however,...

journal_title：Journal of endocrinological investigation

authors： Glinoer D,Naeije R,Golstein J,Fernandez-Deville M,Vanhaelst L

更新日期：1980-01-01 00:00:00

abstract：:N-Methyl-D-Aspartate(NMDA)-sensitive glutamate receptors, are critically involved in the induction of the learning process. Activation of NMDA receptors by glutamate lead to massive influx of extracellular Ca2+, with ensuing activation of a variety of Ca(2+)-dependent enzymes, including protein kinase C. This triggers...

journal_title：Journal of endocrinological investigation

authors： Caruso S,Agnello C,Campo MG,Nicoletti F

更新日期：1993-12-01 00:00:00

abstract：:Human thyroid blood flow rate (TBF) was measured during operations by electromagnetic flowmetry in 75 euthyroid patients with normal thyroid tissue, nodular goiter, or solitary adenoma, and in 22 hyperthyroid patients with diffuse or nodular goiter. Blood flow rate was measured in one to four of the thyroid arteries. ...

journal_title：Journal of endocrinological investigation

authors： Tegler L,Gillquist J,Anderberg B,Lundström B,Johansson H

更新日期：1981-07-01 00:00:00

abstract：:The prevalence of primary aldosteronism has increased since many patients who were previously considered as being affected by low renin essential hypertension are actually satisfying the new diagnostic criteria using plasma aldosterone/ plasma renin activity (PRA) ratio. Many of these cases could be classified as subc...

journal_title：Journal of endocrinological investigation

authors： Armanini D,Fiore C

更新日期：2009-07-01 00:00:00

abstract：:To evaluate the effect of weight loss and diet therapy on plasma sex hormone behavior in male obesity, 9 men with a BMI of 43.4 +/- 6.3 participated in an 8-week semistarvation program [whose energy content ranged from 320 to 500 k calorie/day (proteins 44 to 60 g and carbohydrates 54 to 81 g per day)] followed by a t...

journal_title：Journal of endocrinological investigation

authors： Pasquali R,Casimirri F,Melchionda N,Fabbri R,Capelli M,Platè L,Patrono D,Balestra V,Barbara L

更新日期：1988-03-01 00:00:00

abstract：:Dopamine in humans inhibits the secretion of luteinizing hormone (LH), follicular stimulating hormone (FSH), thyroid stimulating hormone (TSH) and prolactin (PRL), and is a stimulator of growth hormone (GH) secretion. Dopamine-D1 receptor stimulation with fenoldopam increases basal PRL levels, suppresses TSH, and incr...

journal_title：Journal of endocrinological investigation

authors： Grodum E,Andersen M,Hangaard J,Koldkjaer O,Hagen C

更新日期：1998-05-01 00:00:00

abstract：:In obesity there is a clear reduction of both spontaneous and stimulated GH secretion. Furthermore, in obese patients the somatotrope responsiveness to provocative stimulation is selectively refractory to the inhibitory effect of glucose load. It has been hypothesized that hyperinsulinism of obese patients could play ...

journal_title：Journal of endocrinological investigation

authors： Limone P,Oleandri SE,Ajmone Catt P,Grottoli S,Frangioni C,Avogadri E,Perrin M,Valetto MR,Maccario M

更新日期：1997-11-01 00:00:00

abstract：:The role of androgens in human sexuality as regards the mechanism of erection and the pathogenesis of impotence is under debate. In addition, it is difficult to define the psychosocial impact of both hypogonadism and androgen replacement. However, sexual hormones largely influence mood, well-being, and quality of life...

journal_title：Journal of endocrinological investigation

authors： Carosa E,Volpe R,Martini P,Brandetti F,Di Stasi SM,Lombardo F,Salacone P,Sgrò P,Gandini L,Lenzi A,Jannini EA

更新日期：2005-01-01 00:00:00

abstract：:Scavenger receptor A (SR-A) is the main receptor through which oxidized LDL (oxLDL) and advanced glycation end products get into the cells. The aim of the present study was to investigate the effect of an ACE inhibitor, perindopril, on the expression of SR-A in renal tubulointerstitium of diabetic rats. Diabetes was i...

journal_title：Journal of endocrinological investigation

authors： Sun L,Wen JH,Sun HL,Shu XC,Hu F,Yin DC,Yang Q,Zeng YJ,Sun Y,Liu L

更新日期：2012-05-01 00:00:00

abstract：:Much research has demonstrated that in late pregnancy glucose administration causes a marked increase of peripheral insulin levels. To ascertain whether this particular increase is due to increased insulin secretion and/or to reduced hepatic insulin removal, we measured blood glucose, plasma C-peptide and plasma insul...

journal_title：Journal of endocrinological investigation

authors： Piva I,Erle G,Thiella M,Lora L,Strazzabosco M,Sicolo N,Federspil G

更新日期：1991-11-01 00:00:00

abstract：:IGF-I stimulates protein synthesis, lowers blood glucose, and affects cell differentiation. The main production site of IGF-I is the liver. One of its binding proteins, IGFBP-1, is also produced by the liver. It is well known that ethanol affects the function of the human liver. Long-term alcohol abuse may therefore n...

journal_title：Journal of endocrinological investigation

authors： Röjdmark S,Brismar K

更新日期：2001-07-01 00:00:00

abstract：:Dopamine agonists have been associated with increased risk of cardiac valve regurgitation in patients with Parkinson's disease. Whether these drugs might be harmful for patients with hyperprolactinemia is still unsettled. Occasional case reports and 7 studies on the relationship between cabergoline and cardiac valve r...

journal_title：Journal of endocrinological investigation

authors： Bogazzi F,Manetti L,Raffaelli V,Lombardi M,Rossi G,Martino E

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:We examined auxological changes in growth hormone (GH)-treated children in Italy using data from the Italian cohort of the multinational observational Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS) of pediatric patients requiring GH treatment. METHODS:We studied 711 children (me...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Iughetti L,Loche S,Maghnie M,Vottero A,GeNeSIS National Board on behalf of the GeNeSIS Italian Investigators.

更新日期：2016-06-01 00:00:00