In vitro detection of glycoprotein production and secretion by human nonfunctioning pituitary adenomas.

abstract：:The calcitonin (CT) concentration has been determined in the serum of 17 patients with different pituitary diseases. More or less elevated levels were found in 7 of them. No definite correlation has been observed between the immunoreactive CT and the different pituitary hormones. ...

journal_title：Journal of endocrinological investigation

authors： Ziliotto D,Luisetto G,Cecchini M,Gastaldo M,Francia G,Padovan L,Heynen G

更新日期：1980-01-01 00:00:00

abstract：:Signals that determine skeletal cell fate, function and apoptosis are critical to normal bone remodeling. Skeletal cells synthesize growth factors; some regulate cell replication, others regulate osteoblastic differentiation. Bone morphogenetic proteins (BMP) and Wnts induce the differentiation of mesenchymal cells to...

journal_title：Journal of endocrinological investigation

authors： Canalis E,Deregowski V,Pereira RC,Gazzerro E

更新日期：2005-01-01 00:00:00

abstract：:We report a rare case of bilateral adrenocortical adenomas causing ACTH-independent Cushing's syndrome at different periods 9 yr apart. The subject, a 24-yr-old woman, in June 1989 had a typical Cushingoid appearance. Her baseline plasma cortisol levels did not show a diurnal rhythm and she had a very low baseline pla...

journal_title：Journal of endocrinological investigation

authors： Tung SC,Wang PW,Huang TL,Lee WC,Chen WJ

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Chronic alcohol abuse is a risk factor for osteoporosis and fractures, whose pathogenesis is still unclear. We investigated the influence of alcoholism and other risk factors on calcium and skeletal metabolism, bone mineral density (BMD), and fractures. MATERIALS AND METHODS:In 51 chronic male alcoholics wi...

journal_title：Journal of endocrinological investigation

authors： Santori C,Ceccanti M,Diacinti D,Attilia ML,Toppo L,D'Erasmo E,Romagnoli E,Mascia ML,Cipriani C,Prastaro A,Carnevale V,Minisola S

更新日期：2008-04-01 00:00:00

abstract：:Endemic goiter in Morocco is localized in the Rif and Atlas mountains. In this study, performed in the Skoura-Toundoute areas (high Atlas), we demonstrate that iodine deficiency is the main factor involved in the development of endemic goiter. However it may not constitute the only etiological factor. The median urina...

journal_title：Journal of endocrinological investigation

authors： Aquaron R,Zarrouck K,el Jarari M,Ababou R,Talibi A,Ardissone JP

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Achieving biochemical control (normalization of insulin-like growth factor-1 [IGF-1] and growth hormone [GH]) is a key goal in acromegaly management. However, IGF-1 and GH fluctuate over time. The true potential impact of time-varying biochemical control status on comorbidities is unclear and relies on multiple...

journal_title：Journal of endocrinological investigation

authors： Colao A,Grasso LFS,Di Cera M,Thompson-Leduc P,Cheng WY,Cheung HC,Duh MS,Neary MP,Pedroncelli AM,Maamari R,Pivonello R

更新日期：2020-04-01 00:00:00

abstract：:The purpose of this study was to detect in vitro growth hormone (GH) and prolactin (PRL) secretion from adenomas clinically associated with GH or PRL hypersecretion. The reverse hemolytic plaque assay (RHPA) was applied in order to reveal possible differences among various morphologic adenoma types, and to examine the...

journal_title：Journal of endocrinological investigation

authors： Thodou E,Kontogeorgos G,Kyrodimou E,Salla H,Ramyar L,Vamvassakis E,Piaditis G,Anagnostopoulos N,Tzanis S,Levedis A,Rologis D,Asa SL

更新日期：1999-10-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like material was found in human retina obtained at autopsy from eyes used for corneal grafts. The TRH-like material was extracted with methanol and was found to be indistinguishable from synthetic TRH in its immunoreactivity and bioreactivity and in its proteolytic degradation by f...

journal_title：Journal of endocrinological investigation

authors： Martino E,Nardi M,Vaudagna G,Simonetti S,Cilotti A,Pinchera A,Venturi G,Seo H,Baschieri L

更新日期：1980-07-01 00:00:00

abstract：:Because women affected by polycystic ovary syndrome (PCOS) present an increased cardiovascular risk, the safety of estroprogestin treatment is debated and contrasting data have been reported. However, cardiovascular risk is not the same in all PCOS women and individual cardiovascular risk should be assessed before sta...

journal_title：Journal of endocrinological investigation

authors： Carmina E

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:We developed clinical practice guidelines to assess the individual risk-benefit profile of androgen replacement therapy in adult male hypogonadism (HG), defined by the presence of specific signs and symptoms and serum testosterone (T) below 12 nmol/L. PARTICIPANTS:The task force consisted of eight clinicians...

journal_title：Journal of endocrinological investigation

authors： Isidori AM,Balercia G,Calogero AE,Corona G,Ferlin A,Francavilla S,Santi D,Maggi M

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the possible association of insulin-like growth factor-1 (IGF-1) with the pathogenesis of non-functioning adrenocortical adenomas (NFAs). METHODS:This study included 50 female patients (mean age 54 years) with NFAs, 55 patients (mean age 48 years; 20 male, 35 female) wi...

journal_title：Journal of endocrinological investigation

authors： Bahadir CT,Ecemis GC,Atmaca H

更新日期：2018-11-01 00:00:00

abstract：:As it has been hypothesized that IGF-binding proteins (IGFBPs) may have a role as autocrine/paracrine factors in regulating the local actions of the insulin-like growth factors (IGFs) in the ovary, we studied the production of the IGFBPs by human granulosa cells (GC) in culture and the role of IGFBP-3 in the modulatio...

journal_title：Journal of endocrinological investigation

authors： Barreca A,Artini PG,Cesarone A,Arvigo M,D'Ambrogio G,Genazzani AR,Giordano G,Minuto F

更新日期：1996-01-01 00:00:00

abstract：:GH response to an iv bolus of growth-hormone-releasing hormone (GHRH 1-44, 2 micrograms/kg iv) was evaluated in 17 prepubertal children with total GH deficiency (GHD), 6 with partial GHD and in 7 prepubertal normal but short children tested as control. GH response to conventional pharmacological (insulin and arginine ...

journal_title：Journal of endocrinological investigation

authors： Bozzola M,Tatò L,Cisternino M,Nava C,Valtorta A,Chiesa M,Severi F,Gaburro D

更新日期：1986-12-01 00:00:00

abstract：:The 1865 volume of the "II Morgagni", one of the most important Italian medical journals of the 19th century, presented two important articles, milestones for further scientific studies in the field of sexual differentiation. One was the original description of the "ramified cells" of testicular tubules by E. Sertoli,...

journal_title：Journal of endocrinological investigation

authors： Virdis R

更新日期：2005-11-01 00:00:00

abstract：:Cortistatin (CST), a 17-amino acid peptide partially homologous to somatostatin (SRIF), has been originally isolated from the cerebral cortex and recently found in monocytes and macrophages of the immune system. CST binds all 5 SRIF receptors, as well the GH secretagogue (GHS)/ghrelin receptors. CST exerts sleep promo...

journal_title：Journal of endocrinological investigation

authors： Papotti M,Tarabra E,Allia E,Bozzalla-Cassione F,Broglio F,Deghenghi R,Ghigo E,Muccioli G

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:Although two studies have shown that Addison's disease (AD) is still a potentially lethal condition for cardiovascular, malignant, and infectious diseases, a recent retrospective study showed a normal overall mortality rate. Differently from secondary hypoadrenalism, scanty data exist on the role of conventio...

journal_title：Journal of endocrinological investigation

authors： Giordano R,Marzotti S,Balbo M,Romagnoli S,Marinazzo E,Berardelli R,Migliaretti G,Benso A,Falorni A,Ghigo E,Arvat E

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:ABSTRACT. Several data show that meal intake and nutritional status regulate circulating ghrelin concentrations in humans. Ghrelin mainly circulates in two different forms: octanoyl and des-octanoyl ghrelin. Most circulating ghrelin is des-octanoyl ghrelin which is considered inactive because it lacks endocr...

journal_title：Journal of endocrinological investigation

authors： Lucidi P,Murdolo G,Di Loreto C,Parlanti N,De Cicco A,Ranchelli A,Fatone C,Taglioni C,Fanelli C,Santeusanio F,De Feo P

更新日期：2004-05-01 00:00:00

abstract：:Although TRIAC is bound at least twice as avidly to nuclear receptor as T3, its thyromimetic potency is relatively low and its effect at the pituitary level on thyrotropin (TSH) secretion seems to be dissociated from that at the peripheral tissue level. In order to gain further insight into the complex effects of this...

journal_title：Journal of endocrinological investigation

authors： Beck-Peccoz P,Sartorio A,De Medici C,Grugni G,Morabito F,Faglia G

更新日期：1988-02-01 00:00:00

abstract：:In 1992 a significant relationship between bone turnover and the vitamin D receptor (VDR) genotype was reported in Australian subjects of UK-Irish decent. Since then, several groups have investigated the relationship between VDR and other bone-related genotypes, bone mass and bone turnover in several populations. Howe...

journal_title：Journal of endocrinological investigation

authors： Sheehan D,Bennett T,Cashman KD

更新日期：2001-04-01 00:00:00

abstract：:Vitamin D via its receptor has essential actions on parathyroid cells, inhibiting PTH secretion, and parathyroid cell proliferation. While the effects of vitamin D depletion in the pathogenesis of secondary hyperparathyroidism in elderly individuals or in the occurrence of parathyroid hyperplasia in patients with rena...

journal_title：Journal of endocrinological investigation

authors： Nuti R,Merlotti D,Gennari L

更新日期：2011-07-01 00:00:00

abstract：:Recent evidence suggests that patients with traumatic brain injury (TBI) are at substantial risk of hypopituitarism. The pathomechanisms, however, are not completely understood yet. Little is known about the association of morphological changes in the sella region with pituitary function in TBI. In this study, we asse...

journal_title：Journal of endocrinological investigation

authors： Schneider HJ,Sämann PG,Schneider M,Croce CG,Corneli G,Sievers C,Ghigo E,Stalla GK,Aimaretti G

更新日期：2007-04-01 00:00:00

abstract：:It has been shown that human calcitonin (hCT) is absorbed through the nasal mucosa when administered together with promoters like sodium glycocholate (SGC) or dihydrofusinate. The aim of this study was to compare the clinical and metabolic effect of intranasal (in) and intramuscular (im) hCT in patients with osteoporo...

journal_title：Journal of endocrinological investigation

authors： Pontiroli AE,Pajetta E,Calderara A,Alberetto M,Pozza G,Manganelli V,Resmini G,Tessari L,Maresca V

更新日期：1991-01-01 00:00:00

abstract：:To assess the role of the renin-angiotensin system in the control of aldosterone reease in response to heat exposure, 6 sodium restricted subjects were studied on three random experimental days: a control day and two heat exposure days (46C, 35 mbar, 90 min) with and without propranolol. Plasma aldosterone, renin acti...

journal_title：Journal of endocrinological investigation

authors： Brandenberger G,Follenius M,Oyono S

更新日期：1980-10-01 00:00:00

abstract：:We studied the effects of high doses of methimazole (MMI) or propylthiouracil (PTU) on thyroid-stimulating antibody (TSAb), antithyroid microsomal (MCHA) and antithyroglobulin (TGHA) levels in Graves' disease and Hashimoto's thyroiditis. Thirty Graves' hyperthyroid patients were treated for 14 +/- 8 months (mean +/- S...

journal_title：Journal of endocrinological investigation

authors： Romaldini JH,Werner MC,Rodrigues HF,Teixeira VL,Werner RS,Farah CS,Bromberg N

更新日期：1986-06-01 00:00:00

abstract：:The article "EStradiol and PRogesterone in In vitro ferTilization (ESPRIT): a multicenter study evaluating third‑ versus second‑generation estradiol and progesterone immunoassays. ...

journal_title：Journal of endocrinological investigation

authors： Polyzos NP,Anckaert E,Drakopoulos P,Tournaye H,Schiettecatte J,Donner H,Bobba G,Miles G,Verhagen-Kamerbeek WDJ,Bosch E

更新日期：2020-09-01 00:00:00

abstract：:In six patients suffering from amyotrophic lateral sclerosis we evaluated changes of T4, T3, TSH, PRL, and GH during treatment by continuous iv infusion of TRH for at least 15 days. No clinical improvement was detected. A significant rise of thyroid hormone levels was observed, as well as an upward trend of basal TSH ...

journal_title：Journal of endocrinological investigation

authors： Chiodini PG,Attanasio R,Liuzzi A,Cozzi R,Orlandi P,De Palo C,Dallabonzana D,Girotti F,Testa D

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:Graves' orbitopathy (GO) is an inflammatory orbital disease of autoimmune origin with the potential to cause severe functional and psychosocial effects. The pathogenesis has not been fully elucidated. We investigated whether DNA methylation was associated with GO incidence in Chinese patients. MATERIALS AND ...

journal_title：Journal of endocrinological investigation

authors： Xin Z,Hua L,Shi TT,Tuo X,Yang FY,Li Y,Cao X,Yang JK

更新日期：2018-06-01 00:00:00

abstract：:A 41-year-old male with primary hypothyroidism and a huge TSH-secreting pituitary tumor presented with a bleeding nasal mass that was initially misdiagnosed as a paraganglioma. Other unique features of the case include lack of complaints related to hypothyroidism, an extremely elevated TSH level of 3474 mU/l, and a lo...

journal_title：Journal of endocrinological investigation

authors： Ghannam NN,Hammami MM,Muttair Z,Bakheet SM

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:In contrast with maximal voluntary resistance exercise, which is allegedly considered a potent GH stimulus in young subjects, evaluation of GH response to whole-body vibrations (WBV) has yielded conflicting results. METHODS:The acute effects of WBV alone (test A), maximal voluntary isometric contractions (M...

journal_title：Journal of endocrinological investigation

authors： Sartorio A,Agosti F,De Col A,Marazzi N,Rastelli F,Chiavaroli S,Lafortuna CL,Cella SG,Rigamonti AE

更新日期：2011-03-01 00:00:00

abstract：:A 34-yr-old nulliparous black woman presented with hair loss, facial hirsutism, irregular menses and infertility associated with greatly increased serum total testosterone levels. The adrenal glands and the ovaries were normal on radiological and ultrasonographic investigation. Catheterization of the veins draining fr...

journal_title：Journal of endocrinological investigation

authors： Marcondes JA,Nery M,Mendonça BB,Hayashida SA,Halbe HW,Carvalho FM,Wajchenberg BL

更新日期：1997-12-01 00:00:00