Puerperal breast feeding does not stimulate circulating opioids in humans.

Abstract:

:ACTH, beta lipotropin (beta LPH), beta endorphin (beta EP), Prolactin (PRL) and Cortisol were measured in the first five days of puerperium at 9:00, before and 30 minutes after suckling, in 7 healthy lactating women. With the exception of PRL plasma levels which decline, although remaining at high concentrations during the observation period, all the other parameters showed a sudden fall from the high levels found at delivery, reaching stable normal levels (beta LPH, beta EP, Cortisol) or concentrations which were 50% lower than normal (ACTH), from the second day of puerperium. Suckling confirms its capacity to release plasma PRL, while all the other indices remain unmodified. Despite the experimental evidence that serotoninergic neurons are involved both in the PRL response to suckling and the circadian rhythmicity and stress response of proopiocortin-related peptides, the present results suggest that breast feeding is not a stressful situation, as no typical proopiocortin-related peptide response is evident, and that the activation of PRL release is related to stimulation of serotoninergic neurons which differ from those involved in the control of proopiocortin-related peptide secretion.

journal_name

J Endocrinol Invest

authors

Genazzani AR,Facchinetti F,Parrini D,Petraglia F,La Rosa R,Puggioni R,D'Antona N

doi

10.1007/BF03350534

subject

Has Abstract

pub_date

1982-11-01 00:00:00

pages

367-71

issue

6

eissn

0391-4097

issn

1720-8386

journal_volume

5

pub_type

杂志文章
  • Persistent pituitary resistance to thyroid hormone in congenital versus later-onset hypothyroidism.

    abstract::The pituitary and peripheral responses to L-T4 and L-T3 therapy were studied in 12 patients with congenital goitrous hypothyroidism, in 10 patients with an ectopic thyroid and onset of hypothyroidism at 3-8 years of age, and in 6 patients with adult-onset hypothyroidism, after they had had their chronic thyroid hormon...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348554

    authors: Cavaliere H,Medeiros-Neto GA,Rosner W,Kourides IA

    更新日期:1985-12-01 00:00:00

  • Non-invasive and real-time proliferative activity estimation based on a quantitative radiomics approach for patients with acromegaly: a multicenter study.

    abstract:BACKGROUND:Proliferative activity prediction is important for determining individual treatment strategies for patients with acromegaly, and tumor proliferative activity is usually measured by the expression of Ki-67. OBJECTIVE:This study aimed to assess the value of a magnetic resonance imaging (MRI)-based radiomics a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-019-01159-7

    authors: Fan Y,Chai Y,Li K,Fang H,Mou A,Feng S,Feng M,Wang R

    更新日期:2020-06-01 00:00:00

  • Biphasic insulin aspart 30: better glycemic control than with premixed human insulin 30 in obese patients with Type 2 diabetes.

    abstract:AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345673

    authors: Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

    更新日期:2009-01-01 00:00:00

  • Reproducibility and validity of the Italian version of the International Physical Activity Questionnaire in obese and diabetic patients.

    abstract:PURPOSE:Aims of this study were to evaluate the agreement between the short and long versions of the International Physical Activity Questionnaire (IPAQ: Italian versions), their reproducibility (agreement and reliability) and construct validity (relative to pedometry) in a clinical population. METHODS:Ninety patients...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-017-0746-3

    authors: Minetto MA,Motta G,Gorji NE,Lucini D,Biolo G,Pigozzi F,Portincasa P,Maffiuletti NA

    更新日期:2018-03-01 00:00:00

  • Graves' disease and thyroid associated ophthalmopathy triggered by 131I treatment of non-toxic goiter.

    abstract::A 39-year-old Danish woman was treated with an oral dose of 400 MBq 131I for a non-toxic goiter with compression symptoms. Serum anti-TPO and TSH receptor antibodies were negative before radioiodine therapy. The patient developed hyperthyroidism four months after treatment and ophthalmopathy after another three months...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343594

    authors: Nygaard B,Metcalfe RA,Phipps J,Weetman AP,Hegedüs L

    更新日期:1999-06-01 00:00:00

  • Painless thyroiditis developed in a patient with Sheehan's syndrome.

    abstract::We experienced an unusual combination of painless thyroiditis and Sheehan's syndrome in a single patient. A 29-year-old postpartum woman was referred to us for suspected Sheehan's syndrome. Endocrine tests confirmed the diagnosis, but, unexpectedly, her thyroid hormone levels in the plasma were elevated. Based on the ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350313

    authors: Watanobe H,Kawabe H

    更新日期:1997-06-01 00:00:00

  • Impact of age on plasma vaspin concentration in a group of normal Chinese people.

    abstract:PURPOSE:Visceral adipose tissue-derived serine protease inhibitor (vaspin) is an adipocytokine with insulin-sensitizing effects. Accumulating data implied that vaspin represents a compensatory mechanism but it is unknown how vaspin change during ageing. This study was designed to examine the correlation between plasma ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-016-0533-6

    authors: Xu X,Wen J,Lu Y,Ji H,Zhuang J,Su Y,Liu B,Li H,Xu Y

    更新日期:2017-02-01 00:00:00

  • Primary hyperparathyroidism-associated polyostotic fibrous dysplasia: absence of McCune-Albright syndrome mutations.

    abstract::Several cases of sporadic primary hyperparathyroidism in association with fibrous dysplasia of the bone have been reported in the English literature. Since fibrous dysplasia is a major feature and hyperparathyroidism is occasionally found in the McCune-Albright syndrome, we hypothesized that such cases may represent a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348018

    authors: Hammami MM,al-Zahrani A,Butt A,Vencer LJ,Hussain SS

    更新日期:1997-10-01 00:00:00

  • Developmental patterns of serum 3 alpha-androstanediol glucuronide.

    abstract::3 alpha-androstanediol glucuronide (3 alpha diolG) is a marker of peripheral tissue androgen metabolism. There are no previous data regarding complete paediatric reference ranges for 3 alpha diolG. In order to obtain reference values for 3 alpha diolG we have measured serum levels of 3 alpha diolG in 283 healthy child...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346892

    authors: Rittner HL,Lee PD,Blum WF,Doerr HG,Steiss J,Kreuder J,Rascher W,Kiess W

    更新日期:1997-03-01 00:00:00

  • Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-GLy) on melatonin secretion by the pineal gland of young and old rats.

    abstract::The pineal gland contains many peptides known to be implicated in melatonin production. We examined the effects of a synthetic pineal tetrapeptide Ala-Glu-Asp-Gly on melatonin secretion by the pineal gland. The tetrapeptide effects on pineal gland melatonin secretion were studied in young (9 weeks) and old (27 months)...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345159

    authors: Djeridane Y,Khavinson VKh,Anisimov VN,Touitou Y

    更新日期:2003-03-01 00:00:00

  • Growth hormone variants: a potential avenue for a better diagnostic characterization of growth hormone deficiency in children.

    abstract::Human GH (hGH) is a heterogeneous protein hormone consisting of several isoforms. This heterogeneity is the consequence of multiple hGH genes, mRNA splicing, post-translational modifications, and peripheral metabolism, and it represents one important reason for the disparity among GH assay results from different labor...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.3275/8647

    authors: Rigamonti AE,Bozzola M,Banfi G,Meazza C,Müller EE,Cella SG

    更新日期:2012-11-01 00:00:00

  • Healthy centenarian subjects: the effect of red wine consumption on liver function tests.

    abstract::Liver function is well maintained with increasing age. The aim of our study was to investigate if long-term moderate (

    journal_title:Journal of endocrinological investigation

    pub_type: 临床试验,杂志文章

    doi:

    authors: Pinzani P,Petruzzi E,Orlando C,Malentacchi F,Petruzzi I,Pazzagli M,Masotti G

    更新日期:2005-01-01 00:00:00

  • The use of ultrasensitive thyroglobulin assays reduces but does not abolish the need for TSH stimulation in patients with differentiated thyroid carcinoma.

    abstract::Measurement of serum Tg using ultrasensitive assays is proposed to replace TSH-stimulated Tg measurement in the follow-up of differentiated thyroid cancer (DTC). Aim of our study was to verify this possibility using two ultrasensitive Tg assays. We selected 215 DTC patients with undetectable (<1 ng/ml) basal serum Tg ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7571

    authors: Castagna MG,Tala Jury HP,Cipri C,Belardini V,Fioravanti C,Pasqui L,Sestini F,Theodoropoulou A,Pacini F

    更新日期:2011-09-01 00:00:00

  • Presence of endothelin-1 in the normal and pathological human thyroid.

    abstract::An immunohistochemical study with two rabbit polyclonal antibodies I-AR76 and CA-08-351 against Endothelin-1 (ET-1) was performed in 133 human thyroid specimens: 5 normal thyroids, 30 multinodular goiters (15 toxic and 15 nontoxic), 20 Graves' diseases, 5 Hashimoto's thyroiditis, 26 adenomas (6 Hürthle cell, 16 toxic ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347834

    authors: Lenziardi M,Viacava P,Fiorini I,Castagna M,Nardini V,Pollina L,De Negri F,Goletti O,Di Coscio G,Bevilacqua G

    更新日期:1995-05-01 00:00:00

  • Fuel homeostasis and locomotor behavior: role of leptin and melanocortin pathways.

    abstract:BACKGROUND:While it is now accepted that genes and their products affect food intake, the concept that locomotor behavior or the propensity for physical activity is controlled by neuro hum oral regulators is frequently underappreciated. In mammals, complex interactions have developed to allow the cross-talk between fue...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/s40618-014-0225-z

    authors: Ceccarini G,Maffei M,Vitti P,Santini F

    更新日期:2015-02-01 00:00:00

  • Factor analysis of metabolic syndrome components in severely obese girls and boys.

    abstract:AIMS AND METHODS:Factor analysis is a multivariate correlation technique frequently employed to characterise the aggregation of abnormalities underlying the metabolic syndrome (MS), but scarcely used in obese adolescents. Aim of the study was to investigate the clustering of anthropometric and metabolic variables relat...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346506

    authors: Lafortuna CL,Adorni F,Agosti F,De Col A,Zennaro R,Caranti D,Sartorio A

    更新日期:2009-06-01 00:00:00

  • Vitamin D-neutralizing CYP24A1 expression, oncogenic mutation states and histological findings of human papillary thyroid cancer.

    abstract:OBJECTIVE:The aims of the present study were to examine gene and protein expression of the vitamin D-inactivating 24-hyroxylase (CYP24A1) and the activating 1-alpha-hydroxylase (CYP27B1) enzyme in human papillary thyroid cancer (PTC), furthermore, to investigate the association between CYP24A1 expression and numerous c...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-014-0165-7

    authors: Balla B,Tobiás B,Kósa JP,Podani J,Horváth P,Nagy Z,Horányi J,Járay B,Székely E,Krenács L,Árvai K,Dank M,Putz Z,Szabó B,Szili B,Valkusz Z,Vasas B,Győri G,Lakatos P,Takács I

    更新日期:2015-03-01 00:00:00

  • American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules.

    abstract::American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules are systematically developed statements to assist health care professionals in medical decision making for ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,实务指引

    doi:

    authors: Gharib H,Papini E,Paschke R,Duick DS,Valcavi R,Hegedüs L,Vitti P,AACE\/AME\/ETA Task Force on Thyroid Nodules.

    更新日期:2010-01-01 00:00:00

  • Osteocalcin levels in patients with microprolactinoma before and during medical treatment.

    abstract::Osteocalcin (OC) concentration, a specific index of bone formation, was measured in 29 female patients with microprolactinoma (serum prolactin, PRL: 105 +/- 10.9 ng/ml; mean +/- SE). Mean OC levels were significantly lower than in controls (1.7 +/- 0.2 vs 5.1 +/- 0.3 ng/ml; p less than 0.001), being below the normal r...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350694

    authors: Sartorio A,Conti A,Ambrosi B,Muratori M,Morabito F,Faglia G

    更新日期:1990-05-01 00:00:00

  • Prevalence of overweight/obesity, abdominal obesity and metabolic syndrome and atypical cardiometabolic phenotypes in the adult Romanian population: PREDATORR study.

    abstract:PURPOSE:The objectives were to assess the prevalence of overweight/obesity, abdominal obesity and metabolic syndrome (MetS), and to evaluate the characteristics of the metabolically unhealthy lean (MUHL) and metabolically healthy overweight/obese (MHO) phenotypes in a Romanian population-based sample from the PREDATORR...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-016-0470-4

    authors: Popa S,Moţa M,Popa A,Moţa E,Serafinceanu C,Guja C,Catrinoiu D,Hâncu N,Lichiardopol R,Bala C,Popa A,Roman G,Radulian G,Timar R,Mihai B

    更新日期:2016-09-01 00:00:00

  • Thyroid function tests in acute viral hepatitis: relative reduction in serum thyroxine levels due to T4-TBG binding inhibitors in patients with severe liver cell necrosis.

    abstract::Thyroid function tests were evaluated in 34 patients with acute viral hepatitis (AVH) and in 38 healthy controls (C). As expected, AVH patients displayed a significant increase in T4, rT3 and TBG serum levels with respect to C, while FT4 and TSH concentrations were similar. A positive correlation between TBG and T4 wa...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349947

    authors: Pagliacci MC,Pelicci G,Francisci D,Giammartino C,Fedeli L,Stagni G,Nicoletti I

    更新日期:1989-03-01 00:00:00

  • Extensive spherical amyloid deposition presenting as a pituitary tumor.

    abstract::A 71-yr-old man was admitted for further evaluation and trans-sphenoidal surgery of a pituitary tumor. He complained of impotence and decreased libido over a period of about 40 yr. Thirty-eight yr ago he was treated for bilateral gynecomastia with galactorrhea. Endocrinological investigation at presentation revealed o...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345219

    authors: Wiesli P,Brändle M,Brandner S,Kollias SS,Bernays RL

    更新日期:2003-06-01 00:00:00

  • Correction to: In memory of Professor Domenico Andreani.

    abstract::Unfortunately, the author name and his affiliation were published in the original publication. They have now been removed. ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s40618-019-01012-x

    authors:

    更新日期:2019-02-01 00:00:00

  • Enhanced iodine concentrating capacity by the mammary gland in iodine deficient lactating women of an endemic goiter region in Sicily.

    abstract::Iodine balance during pregnancy and lactation was investigated by measuring iodine concentration in the urine of 11 pregnant women, born and living in a moderately iodine deficient endemic goiter area in Northeastern Sicily, collected during the last week of pregnancy, and between the 5th and 7th day after delivery, a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348681

    authors: Vermiglio F,Lo Presti VP,Finocchiaro MD,Battiato S,Grasso L,Ardita FV,Mancuso A,Trimarchi F

    更新日期:1992-02-01 00:00:00

  • Hyperprolactinemia affects spermiogenesis in adult male rats.

    abstract::The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345528

    authors: Aleem M,Choudhari J,Padwal V,Balasinor N,Parte P,Gill-Sharma MK

    更新日期:2005-01-01 00:00:00

  • Immunohistochemical detection of estrogen and progesterone receptors in the normal urinary bladder and in pseudomembranous trigonitis.

    abstract::According to recent studies showing the presence of estrogens receptors (ERs) in the human female lower urinary tract, we performed ER and progesterone receptor (PR) assays in fresh frozen and paraffin embedded biopsies taken from the urinary bladder. Fourteen females undergoing endoscopy during staging for gynecologi...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347639

    authors: Pacchioni D,Revelli A,Casetta G,Cassoni P,Piana P,Tizzani A,Bussolati G,Massobrio M

    更新日期:1992-11-01 00:00:00

  • Screening of follicle-stimulating hormone receptor gene in women with premature ovarian failure in southern Brazil and associations with phenotype.

    abstract::We investigated the presence of mutations/polymorphisms in the FSH receptor (FSHR) gene and their association with phenotype in women with premature ovarian failure (POF) in southern Brazil. Clinical and hormonal variables were determined in 36 46,XX women with primary or secondary amenorrhea before the age of 40 yr, ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346407

    authors: Vilodre LC,Kohek MB,Spritzer PM

    更新日期:2008-06-01 00:00:00

  • A case of hypersensitivity to thyroid hormones with normally functioning thyroid gland and increased nuclear triiodothyronine receptors.

    abstract::A 52-year-old male presented himself with tachycardia crises which appeared first during childhood, increased in frequency without goiter or exophthalmos. Cardiac and adrenergic diseases were excluded. The thyroid function was normal regarding T4, free T4 and T3, TBG, radioiodine uptake, TSH and T3 suppressibility; ho...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349636

    authors: Jaffiol C,Baldet L,Torresani J,Bismuth J,Papachristou C

    更新日期:1990-11-01 00:00:00

  • Early occurrence of a thyroid carcinoma in a patient who developed Graves' disease after treatment for Hodgkin's disease.

    abstract::We report the case of a patient who developed Graves' disease and a papillary thyroid cancer only 5 years after irradiation and adjuvant chemotherapy for Hodgkin's disease. This case is peculiar for the very short latency time between Hodgkin's disease treatment and thyroid cancer development, an event possibly relate...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349835

    authors: Belfiore A,Pellegriti G,Milone G,Vigneri G,Gangemi P,Fiumara A,Vigneri R

    更新日期:1995-12-01 00:00:00

  • Extraprostatic complications of testosterone replacement therapy.

    abstract::Testosterone therapy has been reported to be useful in the treatment of hypogonadism and partial androgen deficiency of the aging male (PADAM) syndrome. Testosterone administration is needed in order to maintain secondary sexual characteristics, muscle mass, bone mineral density, cognitive function and sexual drive. N...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Volpi R,Coiro V,Chiodera P,Saccani-Jotti G,Delsignore R

    更新日期:2005-01-01 00:00:00