Abstract:
:Afferent splanchnic nerve stimulation with different frequencies in Wistar Kyoto rats caused depressor and pressor responses depending on the frequency employed. Similar visceral afferent activation in spontaneously hypertensive rats caused depressor responses at all frequencies of stimulation. It is suggested that the central integrated mechanisms for activating a cardiovascular state change as evoked by visceral afferents may differ in the established hypertensive rat from that of the normotensive.
journal_name
Clin Exp Pharmacol Physioljournal_title
Clinical and experimental pharmacology & physiologyauthors
Koyama S,Manning JWdoi
10.1111/j.1440-1681.1985.tb00300.xsubject
Has Abstractpub_date
1985-01-01 00:00:00pages
37-42issue
1eissn
0305-1870issn
1440-1681journal_volume
12pub_type
杂志文章abstract::1. After a severe burn, a marked decrease in myocardial blood flow results in ischaemic and hypoxic injury, which subsequently leads to apoptosis or necrosis. Phosphatidylinositol 3-kinase (PI3-K)/Akt is an important intracellular signal transduction molecule that regulates cell proliferation, differentiation, glucose...
journal_title:Clinical and experimental pharmacology & physiology
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更新日期:2004-11-01 00:00:00
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