Effect of 1,25-dihydroxyvitamin D3 and nifedipine on prolactin release in normal man.

abstract：:Cerebral ischemia and symptoms of stroke can occur as a rare manifestation in patients with pheochromocytoma. We describe a 45-year-old woman who was admitted because of a right-sided hemiparesis due to an ischemic lesion in the left hypothalamus. The clinical diagnosis of a pheochromocytoma was proven by highly eleva...

journal_title：Journal of endocrinological investigation

authors： Lehmann FS,Weiss P,Ritz R,Harder F,Staub JJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:In obese subjects it has been shown that cortisol (F) contributes to the reduction in insulin sensitivity, suggesting a role in the development of the metabolic syndrome (MS). AIM:The aim of this retrospective study was to evaluate the relationship between F and components of MS in 1,027 obese children and ...

journal_title：Journal of endocrinological investigation

authors： Guzzetti C,Pilia S,Ibba A,Loche S

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:We recently demonstrated a protective effect of the farnesoid X receptor agonist obeticholic acid (OCA) in rat models of bleomycin-induced pulmonary fibrosis (PF). Aim of the present study was to investigate whether the positive effects of OCA treatment are apparent also on ongoing bleomycin-induced PF, i.e., a...

journal_title：Journal of endocrinological investigation

authors： Comeglio P,Filippi S,Sarchielli E,Morelli A,Cellai I,Corno C,Pini A,Adorini L,Vannelli GB,Maggi M,Vignozzi L

更新日期：2019-03-01 00:00:00

abstract：:Benign thyroid nodules represent a very common disorder, the management of which is still controversial. The aim of the present work was to evaluate by ultrasound examination the volume changes of thyroid nodules in post-menopausal women presenting single palpable nodular goiter of recent onset (less than 6 months fro...

journal_title：Journal of endocrinological investigation

authors： Costante G,Crocetti U,Schifino E,Ludovico O,Capula C,Nicotera M,Arturi F,Filetti S

更新日期：2004-01-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) accounts for 80% of all thyroid malignancies, and genetic alterations associated to its etiology remain largely unknown. Chromosomal band 11q13 seems to be one of the most frequently amplified regions in human cancer, providing several candidate genes that need detailed characterization....

journal_title：Journal of endocrinological investigation

authors： Hidalgo M,Saez ME,Martinez-Tello FJ,Moron FJ,Ferrero-Herrero E,Labalde-Martinez M,Rigopoulou D,Ballestin-Carcavilla C,Ruiz A,Royo JL,Ramirez-Lorca R

更新日期：2008-07-01 00:00:00

abstract：:The outcome of radioiodine therapy of Graves' hyperthyroidism was retrospectively evaluated in 274 consecutive patients treated from 1975 to 1984. At 1-yr follow-up, permanent hypothyroidism occurred in 36.9% of patients and the cumulative incidence of hypothyroidism progressively increased up to 79.3% after 7-10 yr. ...

journal_title：Journal of endocrinological investigation

authors： Marcocci C,Gianchecchi D,Masini I,Golia F,Ceccarelli C,Bracci E,Fenzi GF,Pinchera A

更新日期：1990-06-01 00:00:00

abstract：AIM:Adult subjects with Prader-Willi syndrome (PWS) may show several conditions that are associated with an activation of innate immunity such as obesity, deficient GH secretion or hypogonadism. Our aim was to study whether obese adult PWS subjects show an additional low-grade systemic inflammation (LGSI) in relation t...

journal_title：Journal of endocrinological investigation

authors： Caixàs A,Giménez-Palop O,Broch M,Vilardell C,Megía A,Simón I,Giménez-Pérez G,Mauricio D,Vendrell J,Richart C,González-Clemente JM

更新日期：2008-02-01 00:00:00

abstract：:Seventy-one white women within 6 months to 6 years postmenopause were randomly assigned to three treatment groups: (a) placebo, (b) calcium, (c) cyclic estrogen-progestin plus calcium. Calcium was given as calcium carbonate with meals to attain an intake of 1,700 mg daily in the latter two groups. All women received 4...

journal_title：Journal of endocrinological investigation

authors： Aloia JF,Vaswani A,Yeh JK,McGowan DM,Ross P

更新日期：1991-12-01 00:00:00

abstract：UNLABELLED:The aim of this study was to assess the behaviour of insulin sensitivity and insulin resistance (IR) indexes in a group of obese adolescents with Type 2 diabetes mellitus (T2DM) in comparison to obese adolescents without diabetes and normal controls, moreover to compare these parameters with the cardiac auto...

journal_title：Journal of endocrinological investigation

authors： Cerutti F,Rabbia F,Rabbone I,Bobbio A,Ignaccolo MG,Greco G,Bertello MC,Mulatero P,Veglio F,Pacini G

更新日期：2010-09-01 00:00:00

abstract：:Many hirsute women may present a form of functional ovarian hyperandrogenism (FOH), since they show an exaggerated 17-hydroxyprogesterone (17-OHP) response to GnRH agonists administration. As the failure of dexamethasone to reduce testosterone levels may be indicative of an ovarian source of androgen secretion, we eva...

journal_title：Journal of endocrinological investigation

authors： Re T,Barbetta L,Dall'Asta C,Faglia G,Ambrosi B

更新日期：2002-01-01 00:00:00

abstract：:Data concerning the cardiovascular manifestations of primary hyperparathyroidism (PHPT) are inconsistent, which is due, in part, to the decrease in disease severity over the last several decades. In areas where patients tend to be more symptomatic, data support the presence of cardiovascular findings including myocard...

journal_title：Journal of endocrinological investigation

authors： Walker MD,Silverberg SJ

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:We did a meta-analysis with meta-regression to evaluate the relationship between hemoglobin A1c (A1C) reduction and the primary CV outcome of cardiovascular outcome trials (CVOTs). METHODS:We used a random effects meta-analysis of the 12 CVOTs to quantify the effect of A1C reduction on major cardiovascular eve...

journal_title：Journal of endocrinological investigation

authors： Giugliano D,Chiodini P,Maiorino MI,Bellastella G,Esposito K

更新日期：2019-10-01 00:00:00

abstract：:The occurrence of tumors originating from aberrant adrenocortical tissue in ectopic site is very rare. Up to now only two cases of ectopic aldosterone-producing adenoma have been described. We have observed another case of ectopic aldosteronoma, located in the retrocaval region, laterally to the body of the 12th thora...

journal_title：Journal of endocrinological investigation

authors： Mazza E,Papotti M,Durando R,Robecchi A,Camanni F

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Autoimmune polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) or autoimmune polyglandular syndrome type 1 (APS-1) is a rare autosomal recessive genetic disease due to mutations in the AIRE (AutoImmune REgulator) gene. The clinical diagnosis is classically based on the presence of at least two of th...

journal_title：Journal of endocrinological investigation

authors： Fierabracci A,Arena A,Toto F,Gallo N,Puel A,Migaud M,Kumar M,Chengappa KG,Gulati R,Negi VS,Betterle C

更新日期：2020-08-07 00:00:00

abstract：:Two radioimmunological techniques for the measurement of anti-alpha-galactosyl (anti-Gal) antibodies were developed and we demonstrated that this antibody is present in the serum of most untreated patients with Graves' disease, thyroid-associated ophthalmopathy (TAO) and autoimmune thyroiditis. Thyrotropin-binding inh...

journal_title：Journal of endocrinological investigation

authors： Winand RJ,Winand-Devigne J,Cox C,Caulier C,Meurisse M

更新日期：1995-11-01 00:00:00

abstract：:Erythrocytes glutathione (GSH) levels were measured in erythrocytes from 33 subjects, at baseline and after 2-hour glucose loading in order to investigate the effect of glucose ingestion on the erythrocyte GSH. According to the World Health Organisation criteria 18 subjects had normal glucose tolerance (NGT)(mean age ...

journal_title：Journal of endocrinological investigation

authors： Konukoğlu D,Hatemi H,Ozer EM,Gönen S,Akçay T

更新日期：1997-09-01 00:00:00

abstract：:To characterize natriuretic peptide receptor (NPr) gene expression in human tissues, we cloned portions of the cDNAs codifying for NPr with guanylyl cyclase activity (NPr-A and NPr-B) and without guanylyl cyclase activity (NPr-C). Total RNA was extracted from samples taken at surgery from normal human tissues. NPr-A a...

journal_title：Journal of endocrinological investigation

authors： Sarzani R,Dessì-Fulgheri P,Paci VM,Espinosa E,Rappelli A

更新日期：1996-10-01 00:00:00

abstract：:Our study previously showed that estrogen and progesterone stimulated the production of matrix metalloproteinase-14 [MMP-14, or also named membrane type matrix metalloproteinses-1 (MT1-MMP)] in osteoblastic cells. MMP-14 was implied to regulate the function of osteoblasts by degrading bone matrix or growth factors, bu...

journal_title：Journal of endocrinological investigation

authors： Luo XH,Liao EY,Liao HJ,Jin Y,Zhou HD,Huang G

更新日期：2003-11-01 00:00:00

abstract：:Isolated hypothyroxinemia (IH) is defined as a thyroxine level in the lower 5th (severe IH) or 10th percentile (mild IH) of the pregnancy-related reference range and a normal TSH. The etiology of IH remains unknown. This review aims to evaluate the biochemical criteria used to define IH in different published studies ...

journal_title：Journal of endocrinological investigation

authors： Furnica RM,Lazarus JH,Gruson D,Daumerie C

更新日期：2015-02-01 00:00:00

abstract：:In a 41-year-old hirsute woman, severe hypercalcemia led to the discovery of hyperparathyroidism related to the involvement (hyperplasia/or adenoma) of the 4 parathyroid glands. Plasma and urinary DHA, plasma DHA-sulfate and delta 5 steroid precursors were elevated. Steroid hormone hypersecretion was stimulated by hCG...

journal_title：Journal of endocrinological investigation

authors： Guillausseau PJ,Boitard C,Le Charpentier Y,Cedard L,Nahoul K,Blacker C,Kaloustian E,Courtalhac-Kaloustian F,Dubost C,Lubetzki J

更新日期：1987-12-01 00:00:00

abstract：:The activities of total superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) enzymes were measured in cancerous and non-cancerous adjacent tissues from 15 patients with follicular thyroid cancer containing single nodule. SOD and GSH-Px activities were found lower but malondialdehyde levels hi...

journal_title：Journal of endocrinological investigation

authors： Durak I,Bayram F,Kavutcu M,Canbolat O,Oztürk HS

更新日期：1996-05-01 00:00:00

abstract：:A 41-year-old male with primary hypothyroidism and a huge TSH-secreting pituitary tumor presented with a bleeding nasal mass that was initially misdiagnosed as a paraganglioma. Other unique features of the case include lack of complaints related to hypothyroidism, an extremely elevated TSH level of 3474 mU/l, and a lo...

journal_title：Journal of endocrinological investigation

authors： Ghannam NN,Hammami MM,Muttair Z,Bakheet SM

更新日期：1999-06-01 00:00:00

abstract：:Adolescent girls with a history of premature pubarche have an increased incidence of functional ovarian hyperandrogenism [a form of polycystic ovary syndrome (PCOS)] at adolescence, which is usually associated with hyperinsulinemia and dyslipemia. The hyperinsulinemia and lipid disturbances can often be detected in th...

journal_title：Journal of endocrinological investigation

authors： Ibáñez L,de Zegher F,Potau N

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:Few examples of the involvement of a single gene in idiopathic short stature have been described until now. Our aim was to identify the causative gene of proportionate short stature in a large family showing co-segregation of the phenotype with the reciprocal translocation t(10;15)(q22;q24). METHODS:FISH mappi...

journal_title：Journal of endocrinological investigation

authors： Crippa M,Giangiobbe S,Villa R,Bestetti I,De Filippis T,Fatti L,Taurino J,Larizza L,Persani L,Bellini F,Finelli P,Bonati MT

更新日期：2018-08-01 00:00:00

abstract：:Anatomy studies normally precede physiology. While the anatomy of the penis and the biochemical and molecular regulation of erection are largely known, the exact anatomical description of the human clitoris was produced in 1998, the taxonomy of female sexual dysfunctions classified in 1999, and biochemistry of female ...

journal_title：Journal of endocrinological investigation

authors： D'Amati G,di Gioia CR,Proietti Pannunzi L,Pistilli D,Carosa E,Lenzi A,Jannini EA

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:Polycystic ovary syndrome (PCOS) was associated with a number of polymorphisms of genes involved in insulin signaling. So far, they have been studied separately. The aim of this study was to verify the impact of the coexistence of two polymorphisms of insulin signaling. METHODS:One hundred consecutive PCOS wom...

journal_title：Journal of endocrinological investigation

authors： Pappalardo MA,Vita R,Di Bari F,Le Donne M,Trimarchi F,Benvenga S

更新日期：2017-04-01 00:00:00

abstract：:The purpose of this study was to detect in vitro growth hormone (GH) and prolactin (PRL) secretion from adenomas clinically associated with GH or PRL hypersecretion. The reverse hemolytic plaque assay (RHPA) was applied in order to reveal possible differences among various morphologic adenoma types, and to examine the...

journal_title：Journal of endocrinological investigation

authors： Thodou E,Kontogeorgos G,Kyrodimou E,Salla H,Ramyar L,Vamvassakis E,Piaditis G,Anagnostopoulos N,Tzanis S,Levedis A,Rologis D,Asa SL

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:Initial surgery for medullary thyroid cancer (MTC) with no evidence of lymph node involvement in neck compartments consists of total thyroidectomy and prophylactic central neck dissection. This study evaluated the reliability of a radiotracer technique for the intraoperative detection of sentinel lymph nodes (S...

journal_title：Journal of endocrinological investigation

authors： Puccini M,Manca G,Ugolini C,Candalise V,Passaretti A,Bernardini J,Boni G,Buccianti P

更新日期：2014-09-01 00:00:00

abstract：:Anorexia nervosa (AN) is an eating disorder characterized by self-induced starvation due to fear of adiposity. Ghrelin, gastric peptide with potent orexigenic, adipogenic, GH-releasing and metabolic properties, is elevated in AN. We have previously shown that intervention with exogenous ghrelin is not effective in ter...

journal_title：Journal of endocrinological investigation

authors： Miljic D,Djurovic M,Pekic S,Doknic M,Stojanovic M,Milic N,Casanueva FF,Ghatei M,Popovic V

更新日期：2007-10-01 00:00:00

abstract：:Peroxisome proliferator activated receptor (PPAR)gamma plays a pivotal role in regulating adipocyte differentiation and metabolism, but also has an antiproliferative effect in several tissues, including colonic mucosa, where it is highly expressed. Loss-of-function mutations have been reported in about 10% of sporadic...

journal_title：Journal of endocrinological investigation

authors： Bogazzi F,Ultimieri F,Raggi F,Russo D,Brogioni S,Cosci C,Gasperi M,Costa A,Viacava P,Mosca F,Bartalena L,Martino E

更新日期：2003-11-01 00:00:00