Instantaneous wave-free ratio guided multivessel revascularisation during percutaneous coronary intervention for acute myocardial infarction: study protocol of the randomised controlled iMODERN trial.

abstract：BACKGROUND:The juvenile form of Huntington's disease (HD) is a rare disorder. There are no population-based estimates of either its incidence or prevalence in any population in the world. The present study was undertaken to estimate the frequency of juvenile HD in the UK and to examine the range of pharmacological trea...

journal_title：BMJ open

authors： Douglas I,Evans S,Rawlins MD,Smeeth L,Tabrizi SJ,Wexler NS

更新日期：2013-04-03 00:00:00

abstract：:Background Although supporting lifestyle change is an effective way of preventing further events in people with cardiovascular disease, providing access to such interventions is a major challenge. This study aims to investigate whether simple reminders about behaviour change sent via mobile phone text message decrease...

journal_title：BMJ open

authors： Chow CK,Redfern J,Thiagalingam A,Jan S,Whittaker R,Hackett M,Graves N,Mooney J,Hillis GS

更新日期：2012-01-19 00:00:00

abstract：INTRODUCTION:Delayed graft function due to ischaemia-reperfusion injury is a frequent complication in deceased donor renal transplantation. Experimental evidence indicates that remote ischaemic conditioning (RIC) provides systemic protection against ischaemia-reperfusion injury in various tissues. METHODS AND ANALYSIS...

journal_title：BMJ open

authors： Krogstrup NV,Oltean M,Bibby BM,Nieuwenhuijs-Moeke GJ,Dor FJ,Birn H,Jespersen B

更新日期：2015-08-20 00:00:00

abstract：OBJECTIVES:Our work aimed at exploring the relationship between cold spells and acute exacerbation of chronic obstructive pulmonary disease (AECOPD) hospitalisations in Beijing, China, and assessing the moderating effects of the intensities and the durations of cold spells, as well as identifying the vulnerable. DESIG...

journal_title：BMJ open

authors： Liu Y,Chen Y,Kong D,Liu X,Fu J,Zhang Y,Zhao Y,Chang Z,Zhao X,Xu K,Jiang C,Fan Z

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVES:The rate of total knee arthroplasty surgery (TKA) is rising in Australia despite varying impacts of TKA on physical function (PF) in population-based studies. There are potentially modifiable risk factors that could enhance PF after TKA, so we evaluated (1) the levels of PF in persons with TKA and the rest o...

journal_title：BMJ open

authors： Rogers KD,Blyth FM,March LM,Jorm L

更新日期：2013-07-08 00:00:00

abstract：INTRODUCTION:Hypercholesterolaemia is estimated to cause 2.6 million deaths annually and one-third of the cases of ischaemic heart disease. In Argentina, the prevalence of hypercholesterolaemia increased between 2005 and 2013 from 27.9% to 29.8%. Only one out of four subjects with a self-reported diagnosis of coronary ...

journal_title：BMJ open

authors： Gulayin P,Irazola V,Lozada A,Chaparro M,Santero M,Gutierrez L,Poggio R,Beratarrechea A,Rubinstein A

更新日期：2017-01-31 00:00:00

abstract：OBJECTIVES:Rugby has a high injury incidence and therefore BokSmart introduced the Safe Six injury prevention programme in 2014 in an attempt to decrease this incidence. In 2015, BokSmart used a 'targeted marketing approach' to increase the awareness and knowledge of the Safe Six. Therefore, the aim of this study was t...

journal_title：BMJ open

authors： Sewry N,Verhagen E,Lambert M,van Mechelen W,Brown J

更新日期：2017-11-03 00:00:00

abstract：OBJECTIVE:To examine the associations of change in body mass index (BMI) and waist circumference (WC) over an average of 4 years with subsequent mortality risk in middle-aged to older Chinese. DESIGN:Prospective cohort study based on the Guangzhou Biobank Cohort Study. SETTING:Community-based sample. PARTICIPANTS:17...

journal_title：BMJ open

authors： Huang YY,Jiang CQ,Xu L,Zhang WS,Zhu F,Jin YL,Thomas GN,Cheng KK,Lam TH

更新日期：2020-12-04 00:00:00

abstract：OBJECTIVE:To determine if observational studies examining the association of wholegrain foods with cardiovascular disease (CVD) with food industry sponsorship and/or authors with conflicts of interest (COI) with the food industry are more likely to have results and/or conclusions that are favourable to industry than th...

journal_title：BMJ open

authors： Chartres N,Fabbri A,McDonald S,Turton J,Allman-Farinelli M,McKenzie J,Bero L

更新日期：2019-05-19 00:00:00

abstract：INTRODUCTION:Gyejibongneyong-hwan (GBH), also known as Guizhi Fuling formula, and is widely used for uterine fibroids in East Asian countries. Many clinical trials assessing the efficacy and safety of GBH formula for the treatment of dysmenorrhoea have been reported. This review will assess the clinical evidence for an...

journal_title：BMJ open

authors： Lee JA,Park S,Jung J,Jun JH,Choi J,Lee MS

更新日期：2016-09-28 00:00:00

abstract：INTRODUCTION:Current international guidelines recommend non-vitamin K oral anticoagulants (NOACs) for stroke prevention among patients with non-valvular atrial fibrillation (AF) at significant ischaemic stroke risk given the superior safety and comparable efficacy of NOACs over warfarin. Nonetheless, the safety and eff...

journal_title：BMJ open

authors： Zhou M,Chan EW,Hai JJ,Wong CK,Lau YM,Huang D,Lam CC,Tam CCF,Wong YTA,Yung SYA,Chan KWK,Feng Y,Tan N,Chen JY,Yung CY,Lee KL,Choi CW,Lam H,Ng A,Fan K,Jim MH,Yiu KH,Yan BP,Siu CW

更新日期：2020-09-25 00:00:00

abstract：OBJECTIVE:We aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model. DESIGN:A secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative abilit...

journal_title：BMJ open

authors： Mboya IB,Mahande MJ,Mohammed M,Obure J,Mwambi HG

更新日期：2020-10-19 00:00:00

abstract：INTRODUCTION:Pain is an expected and appropriate experience following traumatic musculoskeletal injury. By contrast, chronic pain and disability are unhelpful yet common sequelae of trauma-related injuries. Presently, the mechanisms that underlie the transition from acute to chronic disabling post-traumatic pain are no...

journal_title：BMJ open

authors： Rushton AB,Evans DW,Middlebrook N,Heneghan NR,Small C,Lord J,Patel JM,Falla D

更新日期：2018-04-28 00:00:00

abstract：OBJECTIVE:To assess the effect that accreditation training in fetal growth surveillance and evidence-based protocols had on stillbirth rates in England and Wales. DESIGN:Analysis of mortality data from Office of National Statistics. SETTING:England and Wales, including three National Health Service (NHS) regions (Wes...

journal_title：BMJ open

authors： Gardosi J,Giddings S,Clifford S,Wood L,Francis A

更新日期：2013-12-17 00:00:00

abstract：INTRODUCTION:Developmental alterations to the circadian rhythm, in combination with lifestyle changes (eg, changes in school start time, part-time employment), contribute to insufficient sleep among youth. Insufficient sleep is associated with poor eating behaviours in other developmental stages (ie, childhood, adultho...

journal_title：BMJ open

authors： Doan N,Ferro MA

更新日期：2019-12-11 00:00:00

abstract：OBJECTIVES:This study investigated what kinds of experiences influence regional quota (chiikiwaku) medical students' motivation to practice community healthcare (CH), and the mechanism of this influence, by focusing on their experiences in a community-based medical education (CBME) programme. DESIGN:A qualitative them...

journal_title：BMJ open

authors： Yahata S,Takeshima T,Kenzaka T,Okayama M

更新日期：2021-01-07 00:00:00

abstract：OBJECTIVE:To summarise the findings of an updated Cochrane review of interventions aimed at improving the appropriate use of polypharmacy in older people. DESIGN:Cochrane systematic review. Multiple electronic databases were searched including MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials (fro...

journal_title：BMJ open

authors： Cooper JA,Cadogan CA,Patterson SM,Kerse N,Bradley MC,Ryan C,Hughes CM

更新日期：2015-12-09 00:00:00

abstract：OBJECTIVES:Mortality rates in Scotland are higher, and health inequalities are greater, than in the rest of Western and Central Europe. There was a marked divergence during the 1980s and 1990s in the Scottish rates partly due to rises in alcohol-related and drug-related deaths, suicide and deaths by assault. This study...

journal_title：BMJ open

authors： Parkinson J,Minton J,McCartney G

更新日期：2020-02-09 00:00:00

abstract：OBJECTIVE:This meta-analysis was performed to investigate the correlation between von Willebrand factor (vWF) antigen and hepatic venous pressure gradient (HVPG) and to evaluate the diagnostic performance of vWF to detect clinically significant portal hypertension (CSPH) and severe portal hypertension (SPH). DESIGN:Sy...

journal_title：BMJ open

authors： Zou Z,Yan X,Li C,Li X,Ma X,Zhang C,Ju S,Tian J,Qi X

更新日期：2019-08-30 00:00:00

abstract：:Objectives In 2007, the International Agency for Research on Cancer classified long-term shift work as a probable carcinogen, with the strongest evidence for breast cancer. One proposed mechanism involves night-time light exposure and decreases in melatonin, a circadian rhythmic hormone. It is hypothesised that melato...

journal_title：BMJ open

authors： Langley AR,Graham CH,Grundy AL,Tranmer JE,Richardson H,Aronson KJ

更新日期：2012-01-21 00:00:00

abstract：OBJECTIVES:Treatment patterns for patients with myelodysplastic syndromes (MDS) outside clinical trials are not well described. Our objective was to evaluate treatment patterns and patient characteristics that influence time to disease-modifying therapy in patients with MDS in the USA. DESIGN, PARTICIPANTS AND OUTCOME...

journal_title：BMJ open

authors： Ma X,Steensma DP,Scott BL,Kiselev P,Sugrue MM,Swern AS

更新日期：2018-07-23 00:00:00

abstract：INTRODUCTION:The association between long-chain omega-3 polyunsaturated fatty acids (PUFAs), brain health, cognitive function and mood has been the subject of intensive research. Marine-derived omega-3 PUFAs, such as docosahexaenoic acid and eicosapentaenoic acid, are highly concentrated in neuronal membranes and affec...

journal_title：BMJ open

authors： O' Donovan F,Carney S,Kennedy J,Hayes H,Pender N,Boland F,Stanton A

更新日期：2019-06-22 00:00:00

abstract：OBJECTIVES:There is a wide variation between European countries in antibiotic prescribing for patients in primary care with lower respiratory tract infection (LRTI) that is not explained by case mix and clinical factors alone. Variation in antibiotic prescribing that is not warranted by differences in illness and clini...

journal_title：BMJ open

authors： Brookes-Howell L,Hood K,Cooper L,Little P,Verheij T,Coenen S,Godycki-Cwirko M,Melbye H,Borras-Santos A,Worby P,Jakobsen K,Goossens H,Butler CC

更新日期：2012-08-22 00:00:00

abstract：INTRODUCTION:Reduction in low-density lipoprotein cholesterol (LDL-C) improves clinical outcomes in patients with coronary artery disease. However, rates of lipid-lowering medication adherence are far from ideal. Reducing dosage frequency from multiple dosing to once-daily dosing may improve patients' medication adhere...

journal_title：BMJ open

authors： Wu Z,Wu D,Jiang J,Chen A,Zheng DD,Li J,Dong Y,Chen Y

更新日期：2020-05-17 00:00:00

abstract：OBJECTIVES:The objective of this study was to investigate the role stressors, sociodemographic characteristics and job tasks of health surveillance assistants (HSAs) and to explore major predictors of role stressors and job satisfaction of HSAs in Malawi. SETTING:Data were collected from health centres and hospitals o...

journal_title：BMJ open

authors： Ntopi S,Chirwa E,Maluwa A

更新日期：2020-11-14 00:00:00

abstract：BACKGROUND:A positive patient safety climate within teams has been associated with higher safety performance. The aim of this study was to describe and compare attitudes to patient safety among the various professionals in surgical teams in Swedish operating room (OR) departments. A further aim was to study nurse manag...

journal_title：BMJ open

authors： Göras C,Unbeck M,Nilsson U,Ehrenberg A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of vitreomacular adhesion (VMA), vitreomacular separation (VMS) and absence of vitreous gel due to vitrectomy on macular thickness measured in the spectral domain optical coherence tomographic (SD-OCT) images. DESIGN:A longitudinal, retrospective, observational study. SETTING:Seco...

journal_title：BMJ open

authors： Kumagai K,Hangai M,Furukawa M,Suetsugu T,Ogino N

更新日期：2016-09-30 00:00:00

abstract：OBJECTIVES:To assess medical care and costs of the 3 highest prevalence lumbar disorders-non-specific low back pain (nLBP), intervertebral disc disorder (IDD) and spinal stenosis (SS)-from national billing data to provide basic information for standards of appropriate management. DESIGN:Retrospective analysis of Natio...

journal_title：BMJ open

authors： Ahn YJ,Shin JS,Lee J,Lee YJ,Kim MR,Park KB,Lee JH,Shin KM,Ha IH

更新日期：2016-09-12 00:00:00

abstract：BACKGROUND:Migration is a major global driver of population change. Certain migrants may be at increased risk of infectious diseases, including tuberculosis (TB), HIV, hepatitis B and hepatitis C, and have poorer outcomes. Early diagnosis and management of these infections can reduce morbidity, mortality and onward tra...

journal_title：BMJ open

authors： Pareek M,Eborall HC,Wobi F,Ellis KS,Kontopantelis E,Zhang F,Baggaley R,Hollingsworth TD,Baines D,Patel H,Haldar P,Patel M,Stephenson I,Browne I,Gill P,Kapur R,Farooqi A,Abubakar I,Griffiths C

更新日期：2019-03-07 00:00:00

abstract：INTRODUCTION:The proportion of elderly people is steadily rising worldwide, especially in low-income and middle-income countries, including China. Chronic kidney disease (CKD) is a common disorder in older people. However, little is known about the epidemiology of CKD and its consequences among the elderly. Improvement...

journal_title：BMJ open

authors： Liang S,Wang WL,Zhu FL,Duan SW,Sun XF,Chen XM,Cai GY,Chinese observational prospective study of ageing population with chronic kidney disease (C-OPTION).

更新日期：2018-02-24 00:00:00