Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020.

Abstract:

:Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y lineage without amino acid deletion Δ69/Δ70, circulating mainly between early September and mid-November, was 10% (6-13%) more transmissible than the 501N lineage, and the 501Y lineage with amino acid deletion Δ69/Δ70, circulating since late September, was 75% (70-80%) more transmissible than the 501N lineage.

journal_name

Euro Surveill

authors

Leung K,Shum MH,Leung GM,Lam TT,Wu JT

doi

10.2807/1560-7917.ES.2020.26.1.2002106

subject

Has Abstract

pub_date

2021-01-01 00:00:00

issue

1

eissn

1025-496X

issn

1560-7917

journal_volume

26

pub_type

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