Abstract:
BACKGROUND:Systemic lupus erythematosus (SLE), a systemic autoimmune disease with no known cure, remains poorly understood and patients suffer from many gaps in care. Recent work has suggested that dietary and other lifestyle factors play an important role in triggering and propagating SLE in some susceptible individuals. However, the magnitude of influence of these triggers, how to identify pertinent triggers in individual patients, and whether removing these triggers confers clinical benefit is unknown. OBJECTIVE:To demonstrate that a digital therapeutic intervention, utilizing a mobile app that allows self-tracking of dietary, environmental, and lifestyle triggers, paired with telehealth coaching, added to usual care, improves quality of life in patients with SLE compared with usual care alone. METHODS:In this randomized controlled pilot study, adults with SLE were assigned to a 16-week digital therapeutic intervention plus usual care or usual care alone. Primary outcome measures were changes from baseline to 16 weeks on 3 validated health-related quality of life (HRQoL) tools: Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), Brief Pain Inventory-Short Form (BPI-SF), and Lupus Quality of Life (LupusQoL). RESULTS:A total of 50 patients were randomized (23 control, 27 intervention). In per-protocol analysis, the intervention group achieved significantly greater improvement than the control group in 9 of 11 domains: FACIT-F (34% absolute improvement for the intervention group vs -1% for the control group, P<.001), BPI-SF-Pain Interference (25% vs 0%, P=.02), LupusQoL-Planning (17% vs 0%, P=.004), LupusQoL-Pain (13% vs 0%, P=.004), LupusQoL-Emotional Health (21% vs 4%, P=.02), and LupusQoL-Fatigue (38% vs 13%, P<.001) were significant when controlling for multiple comparisons; BPI-SF-Pain Severity (13% vs -6%, P=.049), LupusQoL-Physical Health (17% vs 3%, P=.049), and LupusQoL-Burden to Others (33% vs 4%, P=.04) were significant at an unadjusted 5% significance level. CONCLUSIONS:A digital therapeutic intervention that pairs self-tracking with telehealth coaching to identify and remove dietary, environmental, and lifestyle symptom triggers resulted in statistically significant, clinically meaningful improvements in HRQoL when added to usual care in patients with SLE. TRIAL REGISTRATION:ClinicalTrials.gov NCT03426384; https://clinicaltrials.gov/ct2/show/NCT03426384.
journal_name
J Med Internet Resjournal_title
Journal of medical Internet researchauthors
Khan F,Granville N,Malkani R,Chathampally Ydoi
10.2196/23868subject
Has Abstractpub_date
2020-10-20 00:00:00pages
e23868issue
10eissn
1439-4456issn
1438-8871pii
v22i10e23868journal_volume
22pub_type
杂志文章abstract:BACKGROUND:The spread of healthy behaviors through social networks may be accelerated by influential individuals. Previous studies have used lay health influencers to prevent sexually transmitted infections (STIs) among internet-using men who have sex with men (MSM). However, there is a lack of understanding of the cha...
journal_title:Journal of medical Internet research
pub_type: 杂志文章,随机对照试验
doi:10.2196/10171
更新日期:2019-01-21 00:00:00
abstract:BACKGROUND:In December 2019, pneumonia cases of unknown origin were reported in Wuhan City, Hubei Province, China. Identified as the coronavirus disease (COVID-19), the number of cases grew rapidly by human-to-human transmission in Wuhan. Social media, especially Sina Weibo (a major Chinese microblogging social media s...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/19087
更新日期:2020-05-17 00:00:00
abstract:BACKGROUND:The long-term effects of mobile health (mHealth) interventions have not been documented, especially in resource-constrained settings. OBJECTIVE:This study aimed to assess the effects of a 1-year mHealth intervention on blood pressure levels and body weight in low-resource urban settings in Peru, 4 years aft...
journal_title:Journal of medical Internet research
pub_type: 杂志文章,随机对照试验
doi:10.2196/14595
更新日期:2020-04-21 00:00:00
abstract:BACKGROUND:In the United States, there is a national shortage of organs donated for transplant. Among the solid organs, most often kidneys are donated by living donors, but the lack of information and complicated processes limit the number of individuals who serve as living kidney donors. Social media can be a tool for...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.6176
更新日期:2016-12-20 00:00:00
abstract:BACKGROUND:Patients are increasingly taking an active role in their health. In doing so, they combine both mass and interpersonal media to gratify their cognitive and affective needs (ie, convergence). Owing to methodological challenges when studying convergence, a detailed view of how patients are using different type...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/18303
更新日期:2020-10-19 00:00:00
abstract:BACKGROUND:The British Columbia Centre for Disease Control implemented a comprehensive Web-based testing service GetCheckedOnline (GCO) in September 2014 in Vancouver, Canada. GCO's objectives are to increase testing for sexually transmitted and blood-borne infections (STBBIs), reach high-prevalence populations facing ...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.7097
更新日期:2017-03-20 00:00:00
abstract:BACKGROUND:Excessive gestational weight gain (GWG) contributes to the development of obesity in mother and child. Internet-based interventions have the potential for delivering innovative and interactive options for prevention of excessive GWG to large numbers of people. OBJECTIVE:The objective of this study was to cr...
journal_title:Journal of medical Internet research
pub_type: 杂志文章,随机对照试验
doi:10.2196/jmir.6644
更新日期:2017-01-09 00:00:00
abstract:BACKGROUND:Influenza is a viral respiratory disease capable of causing epidemics that represent a threat to communities worldwide. The rapidly growing availability of electronic "big data" from diagnostic and prediagnostic sources in health care and public health settings permits advance of a new generation of methods ...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.7101
更新日期:2017-06-15 00:00:00
abstract:BACKGROUND:The Institute of Medicine recommends Survivorship Care Plans (SCPs) for all cancer survivors. However, it is unclear whether certain patient groups may or may not benefit from SCPs. OBJECTIVE:The aim was to assess whether the effects of an automatically generated paper SCP on patients' satisfaction with inf...
journal_title:Journal of medical Internet research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2196/jmir.4914
更新日期:2016-07-08 00:00:00
abstract:BACKGROUND:Patient registries are commonly used to track survival and medical outcomes in large cohorts. However, large-scale collection of health-related quality of life (HRQOL) data is more challenging because such data must be collected directly from patients. Internet-based HRQOL questionnaires are a potential solu...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.1214
更新日期:2010-08-19 00:00:00
abstract:BACKGROUND:Supporting patients to engage in (Web-based) self-management tools is increasingly gaining importance, but the engagement of health care professionals is lagging behind. This can partly be explained by resistance among health care professionals. OBJECTIVE:The aim of this study was to investigate drivers of ...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/14985
更新日期:2019-12-17 00:00:00
abstract:BACKGROUND:Mobile apps are an evolving trend in the medical field. To date, few apps in an oncological context exist. OBJECTIVE:The aim was to analyze the attitude of health care professionals (HCPs) toward telemedicine, mHealth, and mobile apps in the field of oncology. METHODS:We developed and conducted an online s...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.6399
更新日期:2016-11-24 00:00:00
abstract:BACKGROUND:Existing influenza surveillance in the United States is focused on the collection of data from sentinel physicians and hospitals; however, the compilation and distribution of reports are usually delayed by up to 2 weeks. With the popularity of social media growing, the Internet is a source for syndromic surv...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.3532
更新日期:2014-11-14 00:00:00
abstract:BACKGROUND:The traditional vertical system of sharing information from sources of scientific authority passed down to the public through local health authorities and clinicians risks being made obsolete by emerging technologies that facilitate rapid horizontal information sharing. The rise of Public Health 2.0 requires...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.2982
更新日期:2014-01-14 00:00:00
abstract:BACKGROUND:Demand for mental health services, especially for clinical high-risk and early psychosis, has increased, creating a need for new solutions to increase access to and quality of care. Smartphones and mobile technology are potential tools to support coordinated specialty care for early psychosis, given their po...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/16393
更新日期:2019-11-12 00:00:00
abstract:BACKGROUND:A growing body of evidence supports the potential effectiveness of electronic health (eHealth) interventions in managing chronic pain. However, research on the needs and preferences of patients with chronic pain in relation to eHealth interventions is scarce. Eliciting user input in the development of eHealt...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/13205
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Groups and individuals that seek to negatively influence public opinion about the safety and value of vaccination are active in online and social media and may influence decision making within some communities. OBJECTIVE:We sought to measure whether exposure to negative opinions about human papillomavirus (...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.4343
更新日期:2015-06-10 00:00:00
abstract:BACKGROUND:Men continue to smoke in greater numbers than women; however, few interventions have been developed and tested to support men's cessation. Men tend to rely on quitting strategies associated with stereotypical manliness, such as willpower, stoicism, and independence, but they may lack the self-efficacy skills...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.4491
更新日期:2015-08-10 00:00:00
abstract:BACKGROUND:Blended group therapy (bGT) has been investigated a several times for anxiety and depression, but information on patients' adherence to and therapists' perception of the novel format is nonexistent. Furthermore, many studies investigated mainly female and highly educated populations, limiting the validity of...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/11860
更新日期:2019-04-28 00:00:00
abstract:BACKGROUND:Most smokers attempt to quit on their own even though cessation aids can substantially increase their chances of success. Millions of smokers seek cessation advice on the Internet, so using it to promote cessation products and services is one strategy for increasing demand for treatments. Little is known, ho...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.1666
更新日期:2011-08-26 00:00:00
abstract:BACKGROUND:Information has been identified as a commonly unmet supportive care need for those living with cancer (ie, patients and their friends and family). The information needed to help individuals plan their lives around the consequences of cancer, such as the receipt of health care, is an example of an important i...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/20510
更新日期:2020-10-29 00:00:00
abstract:BACKGROUND:In March 2012, the US Centers for Disease Control and Prevention (CDC) launched the first-ever paid national tobacco education campaign. At a cost of US $54 million, "Tips from Former Smokers" (Tips) ran for 3 months across multiple media, depicting the suffering experienced by smokers and their families in ...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.3645
更新日期:2015-01-20 00:00:00
abstract:BACKGROUND:Web-based behavioral programs efficiently disseminate health information to a broad population, and online tailoring may increase their effectiveness. While the number of Internet-based behavioral interventions has grown in the last several years, additional information is needed to understand the characteri...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.1086
更新日期:2009-08-26 00:00:00
abstract:BACKGROUND:Recent years have seen an exponential increase in people with long-term conditions using the Internet for information and support. Prior research has examined support for long-term condition self-management through the provision of illness, everyday, and emotional work in the context of traditional offline c...
journal_title:Journal of medical Internet research
pub_type: 杂志文章,评审
doi:10.2196/jmir.5260
更新日期:2016-03-10 00:00:00
abstract:BACKGROUND:Patients attempt to make appropriate decisions based on their own knowledge when choosing a doctor. In this process, the first question usually faced is that of how to obtain useful and relevant information. This study investigated the types of information sources that are used widely by patients in choosing...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/20910
更新日期:2020-09-16 00:00:00
abstract:BACKGROUND:Youths in South Africa are poor utilizers of HIV health services. Medecins Sans Frontieres has been piloting youth-adapted services at a youth clinic in Khayelitsha, including a peer virtual mentorship program over mobile phones, piloted from March 2015 to May 2016. OBJECTIVE:The objective of this study was...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/14012
更新日期:2019-12-10 00:00:00
abstract:BACKGROUND:Patients who suffer from different diseases may use different electronic health (eHealth) resources. Thus, those who plan eHealth interventions should take into account which eHealth resources are used most frequently by patients that suffer from different diseases. OBJECTIVE:The aim of this study was to un...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/13116
更新日期:2020-03-05 00:00:00
abstract:BACKGROUND:The medical tourism industry is currently popular in India, but there is no confirmation of the common perspectives among the country's medical travelers. OBJECTIVE:This qualitative research study analyzed web-based narratives from health travelers visiting India and described the themes of their experience...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/15665
更新日期:2020-05-14 00:00:00
abstract:BACKGROUND:The health risk assessment (HRA) is a type of health promotion program frequently offered at the workplace. Insight into the underlying determinants of participation is needed to evaluate and implement these interventions. OBJECTIVE:To analyze whether individual characteristics including demographics, healt...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/jmir.2387
更新日期:2013-08-09 00:00:00
abstract:BACKGROUND:The ability to perform vape tricks (ie, blowing large vapor clouds or shapes like rings) using e-cigarettes appeals to youth. Vape tricks are promoted on social media, but the promotion of vape tricks on social media is not well understood. OBJECTIVE:The aim of this study was to examine how vape tricks were...
journal_title:Journal of medical Internet research
pub_type: 杂志文章
doi:10.2196/12709
更新日期:2019-06-18 00:00:00