Abstract:
BACKGROUND:Pathologists face major challenges in breast cancer diagnostics in sub-Saharan Africa (SSA). The major problems identified as impairing the quality of pathology reports are shortcomings of equipment, organization and insufficiently qualified personnel. In addition, in the context of breast cancer, immunohistochemistry (IHC) needs to be available for the evaluation of biomarkers. In the study presented, we aim to describe the current state of breast cancer pathology in order to highlight the unmet needs. METHODS:We obtained information on breast cancer pathology services within population-based cancer registries in SSA. A survey of 20 participating pathology centres was carried out. These centres represent large, rather well-equipped pathologies. The data obtained were related to the known population and breast cancer incidence of the registry areas. RESULTS:The responding pathologists served populations of between 30,000 and 1.8 million and the centres surveyed dealt with 10-386 breast cancer cases per year. Time to fixation and formalin fixation time varied from overnight to more than 72 h. Only five centres processed core needle biopsies as a daily routine. Technical problems were common, with 14 centres reporting temporary power outages and 18 centres claiming to own faulty equipment with no access to technical support. Only half of the centres carried out IHC in their own laboratory. For three centres, IHC was only accessible outside of the country and one centre could not obtain any IHC results. A tumour board was established in 13 centres. CONCLUSIONS:We conclude that breast cancer pathology services ensuring state-of-the-art therapy are only available in a small fraction of centres in SSA. To overcome these limitations, many of the centres require larger numbers of experienced pathologists and technical staff. Furthermore, equipment maintenance, standardization of processing guidelines and establishment of an IHC service are needed to comply with international standards of breast cancer pathology.
journal_name
BMC Health Serv Resjournal_title
BMC health services researchauthors
Ziegenhorn HV,Frie KG,Ekanem IO,Ebughe G,Kamate B,Traore C,Dzamalala C,Ogunbiyi O,Igbinoba F,Liu B,Bauer M,Thomssen C,Parkin DM,Wickenhauser C,Kantelhardt EJdoi
10.1186/s12913-020-05752-ysubject
Has Abstractpub_date
2020-10-02 00:00:00pages
912issue
1issn
1472-6963pii
10.1186/s12913-020-05752-yjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:Venous Thromboembolism (VTE) is a cause of hospital mortality and managing its morbidity is associated with significant expenditure. Uptake of evidenced based guideline recommendations intended to prevent VTE in hospital settings is sub-optimal. This study was conducted to explore clinicians' attitudes and t...
journal_title:BMC health services research
pub_type: 杂志文章,多中心研究
doi:10.1186/1472-6963-11-240
更新日期:2011-09-28 00:00:00
abstract:BACKGROUND:The aim of this project was to assess whether outreach visits would improve the implementation of evidence based clinical practice in the area of falls reduction and stroke prevention in a residential care setting. METHODS:Twenty facilities took part in a randomized controlled trial with a seven month follo...
journal_title:BMC health services research
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1186/1472-6963-4-6
更新日期:2004-04-06 00:00:00
abstract:BACKGROUND:General practitioners often diverge from clinical guidelines regarding spine radiography. This study aimed to identify and describe A) factors general practitioners consider may affect their decisions about ordering plain radiography for back pain and B) barriers to guideline adherence suggested by such fact...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-3-8
更新日期:2003-03-24 00:00:00
abstract:BACKGROUND:Medication non-adherence is a major contributor to poor outcomes in diabetes. Previous research has shown an association between use of mail order pharmacy delivery and better medication adherence, but little is known about the barriers and facilitators to mail order pharmacy use in diabetes patients. This q...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-019-4250-7
更新日期:2019-06-25 00:00:00
abstract:BACKGROUND:During the SARS epidemic, healthcare utilization and medical services decreased significantly. However, the long-term impact of SARS on hospital performance needs to be further discussed. METHODS:A municipal hospital in Taipei City was shut down for a month due to SARS and then became the designated SARS an...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-8-228
更新日期:2008-11-06 00:00:00
abstract:BACKGROUND:Elevated blood pressure is a major risk factor for cardiovascular disease and stroke but patients often discount recommended behavioral changes and prescribed medications. While effective interventions to promote adherence have been developed, cost-effectiveness from the patient's perspective, has not been w...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-017-2451-5
更新日期:2017-08-07 00:00:00
abstract:BACKGROUND:To examine key factors influencing chronic kidney disease (CKD) patients' total expenditure and offer recommendations on how to reduce total cost of CKD care without compromising quality. METHODS:Using the 2002-2011 Medical Expenditure Panel Survey (MEPS) data, our cross-sectional study analyzed 197 patient...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-016-1922-4
更新日期:2016-12-28 00:00:00
abstract:BACKGROUND:Measuring quality of care is essential to improve primary care. Quality of primary care for patients is usually assessed by patient satisfaction questionnaires. However, patients may not be able to judge quality of care without also reflecting their perception of the environment. We determined the effect tha...
journal_title:BMC health services research
pub_type: 杂志文章,多中心研究
doi:10.1186/s12913-016-1647-4
更新日期:2016-08-11 00:00:00
abstract:BACKGROUND:The lack of availability of skilled providers in low- and middle- income countries is considered to be an important barrier to achieving reductions in maternal and child mortality. However, there is limited research on programs increasing the availability of skilled birth attendants in developing countries. ...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-017-2284-2
更新日期:2017-05-18 00:00:00
abstract:BACKGROUND:Attempts to reduce high utilisation of psychiatric inpatient care by targeting the critical time of hospital discharge have been rare. METHODS:This paper presents design and methods of the study "Effectiveness and Cost-Effectiveness of Needs-Oriented Discharge Planning and Monitoring for High Utilisers of P...
journal_title:BMC health services research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1472-6963-8-152
更新日期:2008-07-21 00:00:00
abstract:BACKGROUND:The existence of publicly-accessible datasets comprised a significant opportunity for health services research to evolve into a science that supports health policy making and evaluation, proper inter- and intra-organizational decisions and optimal clinical interventions. This paper investigated the role of p...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-9-197
更新日期:2009-10-29 00:00:00
abstract:BACKGROUND:The current, place-oriented nurse call systems are very static. A patient can only make calls with a button which is fixed to a wall of a room. Moreover, the system does not take into account various factors specific to a situation. In the future, there will be an evolution to a mobile button for each patien...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-11-26
更新日期:2011-02-04 00:00:00
abstract:BACKGROUND:The use of Patient Reported Experience Measures (PREMs) has great potential in healthcare service improvement, but a limited use. This paper presents an empirical case of PREMs innovation in Italy, to foster patient data use up to the ward level, by keeping strengths and addressing weaknesses of previous PRE...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-020-05099-4
更新日期:2020-04-16 00:00:00
abstract:BACKGROUND:Drug costs increasingly pose a burden upon the otherwise inadequate health care resources and rational drug utilization is an important segment of every national health policy. Optimal patient care should be the goal of rational pharmacotherapy, whereby the economic burden of treatment is just one of the ele...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-14-343
更新日期:2014-08-15 00:00:00
abstract:BACKGROUND:Potentially inappropriate prescribing (PIP) in older people is common in primary care and can result in increased morbidity, adverse drug events, hospitalizations and mortality. The prevalence of PIP in Ireland is estimated at 36% with an associated expenditure of over €45 million in 2007. The aim of this pa...
journal_title:BMC health services research
pub_type: 杂志文章,评审
doi:10.1186/1472-6963-13-307
更新日期:2013-08-14 00:00:00
abstract:BACKGROUND:Inadequate antenatal care (ANC) can lead to missed diagnosis of danger signs or delayed referral to emergency obstetrical care, contributing to maternal mortality. In developing countries, ANC quality is often limited by skill and knowledge gaps of the health workforce. In 2011, the Mentorship, Enhanced Supe...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-018-2939-7
更新日期:2018-02-23 00:00:00
abstract:BACKGROUND:Across low-income settings, community volunteers and health committee members support the formal health system - both routinely and amid emergencies - by engaging in health services such as referrals and health education. During the 2014-2015 Ebola epidemic, emerging reports suggest that community engagement...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-017-2414-x
更新日期:2017-07-18 00:00:00
abstract:BACKGROUND:Ergonomic and work stress interventions rarely show long-term positive effect. The municipality participating in this study received orders from the Norwegian Labour Inspectorate due to an identified unhealthy level of time pressure, and responded by effectuating several work environment interventions. The s...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-13-477
更新日期:2013-11-15 00:00:00
abstract:BACKGROUND:For mothers who have just given birth, the postpartum hospital stay is meant to promote an environment where resting, healing and bonding can take place. New mothers, however, face many interruptions throughout the day including multiple visitors and noise caused by medical equipment, corridor conversations ...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-014-0604-3
更新日期:2014-11-29 00:00:00
abstract::In the original publication of this article [1] an author's name needs to be revised from Katrina Nelson to Adrianne Katrina Nelson. ...
journal_title:BMC health services research
pub_type: 已发布勘误
doi:10.1186/s12913-019-4568-1
更新日期:2019-10-22 00:00:00
abstract:BACKGROUND:Healthcare systems are increasingly focusing on outcomes that are the endpoints of care: patient health status and patient satisfaction. The availability of patient satisfaction (PS) data has encouraged research on its relationship with other outcomes, such as mortality. In Italy, an inter-regional performan...
journal_title:BMC health services research
pub_type: 杂志文章,多中心研究
doi:10.1186/s12913-018-2846-y
更新日期:2018-01-29 00:00:00
abstract:BACKGROUND:The increasing diversity of population in European Countries poses new challenges to national health systems. There is a lack of data on accessibility and use of health care services by migrants, appropriateness of the care provided, client satisfaction and problems experienced when confronting the health ca...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-8-207
更新日期:2008-10-07 00:00:00
abstract:BACKGROUND:The existence and magnitude of socio-economic inequalities in health-seeking behaviours for child curative care in Egypt and mechanisms underlying these associations have not been comprehensively assessed. This study examined whether socio-economic position (SEP) was associated with health-seeking behaviours...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-015-1150-3
更新日期:2015-10-24 00:00:00
abstract:BACKGROUND:Falls are very common accidents in a hospital. Various risk factors and risk assessment tools are used to predict falls. However, outcomes of falls such as bone fractures have not been considered in these risk assessment tools, and the performance of risk assessment tools in a Japanese hospital setting is no...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/1472-6963-10-106
更新日期:2010-04-27 00:00:00
abstract:BACKGROUND:In Italy many diabetics still lack adequate care in general practice. We assessed the effectiveness of different strategies for the implementation of an evidence-based guideline for the management of non-complicated type 2 diabetes among General Practitioners (GPs) of Lazio region. METHODS:Three-arm cluster...
journal_title:BMC health services research
pub_type: 杂志文章,随机对照试验
doi:10.1186/1472-6963-7-79
更新日期:2007-06-04 00:00:00
abstract:BACKRGOUND:Good progress is being made towards universal access to contraceptives, however stock-outs still jeopardize progress. A seldom considered but important building block in optimizing supply management is the degree to which health workers feel motivated and responsible for monitoring supply. We explored how an...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-017-2222-3
更新日期:2017-05-02 00:00:00
abstract:BACKGROUND:The engagement of citizens in the development of evidence-based screening programs is internationally supported. The aim of our research was to explore the motivations and reasons of adult citizens in Austria for attending periodic health examinations (PHE) as well as their satisfaction with the way PHE are ...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-018-3640-6
更新日期:2018-10-30 00:00:00
abstract:BACKGROUND:Small Canadian rural maternity services are struggling to maintain core staffing and remain open. Existing evidence states that having to travel to access maternity services is associated with adverse outcomes. The goal of this study is to systematically examine rural maternal and newborn outcomes across thr...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-015-1034-6
更新日期:2015-09-23 00:00:00
abstract:BACKGROUND:Healthcare organisations differ in performance even if they are located in the same country or region. Suitable managerial practices and organisational processes can lead to better health outcomes. As a result, hospitals are constantly looking for managerial arrangements that can improve outcomes and keep co...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-020-05796-0
更新日期:2020-10-16 00:00:00
abstract:BACKGROUND:The concept of frailty is rapidly gaining attention as an independent syndrome with high prevalence in older adults. Thereby, frailty is often related to certain adverse outcomes like mortality or disability. Another adverse outcome discussed is increased health care utilization. However, only few studies ex...
journal_title:BMC health services research
pub_type: 杂志文章
doi:10.1186/s12913-016-1360-3
更新日期:2016-04-14 00:00:00