Transforming the practice of medicine through team science.

Abstract:

BACKGROUND:The translation of biomedical research discoveries into clinical practice is marked by extended timelines (averaging 17 years) and multiple sequential process steps. However, even after a drug, device, diagnostic tool or unique therapeutic procedure successfully navigates through clinical testing to approval, real barriers remain in applying and scaling the innovation in practice. METHODS:Mayo Clinic initiated the Transform the Practice programme to facilitate multidisciplinary team and convergence science to continuously reinvent solutions to address unmet patient needs and accelerate the application of next-generation healthcare solutions. During a 5-year period, 24 programme teams received financial resources, barrier-removing engagement from clinical and research leadership, and enhanced administrative support, including dedicated project managers. RESULTS:The approach created value in facilitating consistent progress toward project objectives and resulted in multiple publications, new extramural funding sources, and implementation of new tests and services into the clinical practice. This report describes the concentrated institutional effort to accelerate the discovery-translation-application continuum in an academic medical centre and highlights successful applications and persistent obstacles. CONCLUSIONS:The Transform the Practice approach is effective in moving high-potential research discoveries closer to implementation in the clinical practice. Its concepts, including the application of structured project management methodology, may be quickly integrated to shorten an organisation's time to implementing its most important discoveries.

journal_name

Health Res Policy Syst

authors

Pitzen JH,Dieter HL,Gronseth DL,Dahl AK,Boyle VL,Maran T,Harper CM Jr,Gores GJ

doi

10.1186/s12961-020-00619-4

subject

Has Abstract

pub_date

2020-09-17 00:00:00

pages

104

issue

1

issn

1478-4505

pii

10.1186/s12961-020-00619-4

journal_volume

18

pub_type

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