当前位置： SCI文献检索 > BMC Oral Health期刊下所有文献 > Clinical characteristics and associated factors of trigeminal neuralgia: experience from Addis Ababa, Ethiopia.

Clinical characteristics and associated factors of trigeminal neuralgia: experience from Addis Ababa, Ethiopia.

Abstract：

BACKGROUND:Trigeminal neuralgia (TN) is considered one of the most painful illnesses known to medical practice. Little is known about TN in Ethiopia. Our study aimed to assess clinical characteristics, treatment, and associated factors of TN. METHOD:A cross-sectional study was conducted on a total of 61 patients with confirmed Trigeminal neuralgia visiting outpatient neurology clinics of two government teaching Hospitals and two private health facilities in Addis Ababa, Ethiopia between June 2019 and March 2020. RESULTS:Our participants' age range between 21 and 78 years with mean ± SD age of 50.7 ± 14.2 years. Males accounted for 50.8%. Twenty-five (41%) reported a prior history of one or more tooth extraction on the painful side. In the majority (68.9%) of the patient's right side of the face was affected. The mandibular nerve was the commonly involved branch (47.5%). Fifty-five (90.2%) of patients fulfilled criteria for classical TN and 9.8% had symptomatic TN. The majority of the participants reported mixed types of pain such as burning, lancinating, and electric shock-like. Well defined trigger zone was identified in one-third (36%) of cases. Carbamazepine was the most commonly prescribed drug with a median dose of 600 mg (IQR: 400 - 1000 mg). Two-third of the patients reported prominent satisfaction. The mean (± SD) dose of carbamazepine used to control the pain was significantly higher among those with dental extraction history as compared to those with no history of dental extraction (736 ± 478.6 mg Vs 661.1 ± 360.4 mg, respectively, T = - 2.06, p = 0.04 95% CI:-213.41 to - 2.98). A statistically significant number of patients who had single branch involvement reported prominent satisfaction with their treatment as compared to those who had more than one branch involvement. (95% CI: 1.3-3.8: p = 0.006). CONCLUSION:The majority of our patients had Classical TN in the mandibular nerve distribution on the right side of the face and well satisfied with carbamazepine only treatment. Furthermore, we observed a higher proportion of dental extraction among our patients, hinting at the scale of miss and delayed-diagnoses. Thus, we recommend conducting a well-designed prospective study to support our findings.

journal_name

BMC Oral Health

journal_title

BMC oral health

authors

Ayele BA,Mengesha AT,Zewde YZ

doi

10.1186/s12903-020-01227-y

subject

Has Abstract

pub_date

2020-09-03 00:00:00

pages

244

issue

issn

1472-6831

pii

10.1186/s12903-020-01227-y

journal_volume

pub_type

杂志文章

在线工具

Clinical characteristics and associated factors of trigeminal neuralgia: experience from Addis Ababa, Ethiopia.