Retraction Note: Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma.

abstract：BACKGROUD:Accumulating evidences indicate that circular RNAs (circRNAs), a class of non-coding RNAs, play important roles in tumorigenesis. However, the function of circRNAs in triple negative breast cancer (TNBC) is largely unknown. METHODS:We performed circRNA microarrays to identify circRNAs that are aberrantly exp...

journal_title：Journal of experimental & clinical cancer research : CR

authors： He R,Liu P,Xie X,Zhou Y,Liao Q,Xiong W,Li X,Li G,Zeng Z,Tang H

更新日期：2017-10-16 00:00:00

abstract：:Gastric cancer (GC) remains one of the most common types of malignant cancer, and the molecular mechanism underlying its metastasis is still largely unclear. MicroRNAs have emerged as important regulators of metastasis because of their ability to act on multiple signaling pathways. In our study, we found that miR-144 ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Liu J,Xue H,Zhang J,Suo T,Xiang Y,Zhang W,Ma J,Cai D,Gu X

更新日期：2015-04-17 00:00:00

abstract：BACKGROUND:The sustained growth of tumors necessitates neovascularization. As one of the potent endogenous vascular inhibitors, endostatin has been widely used in antiangiogenesis therapy for tumor. Cisplatin is normally administered in chemotherapy for lung cancer but accompanied with serious side effects. In the curr...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Bai RZ,Wu Y,Liu Q,Xie K,Wei YQ,Wang YS,Liu K,Luo Y,Su JM,Hu B,Liu JY,Li Q,Niu T,Zhao ZW,Yang L

更新日期：2009-03-05 00:00:00

abstract：:Proliferative activity in 78 glioma specimens was assessed immunohistochemically by determining proliferating index of tumor cells (PTC-PI) and endothelial cells (PEC-PI) using the MIB-1 monoclonal antibody. The PTC-PI of anaplastic astrocytoma (9.0 +/- 5.8: mean + standard deviation) was significantly higher than tha...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Di X,Nishizaki T,Harada K,Kajiwara K,Nakayama H,Ito H

更新日期：1997-06-01 00:00:00

abstract：:The chemical modification of RNA is a newly discovered epigenetic regulation mechanism in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) mRNA modification is the most abundant form of posttranscriptional RNA modification in eukaryotes. Through the development of m6A RNA seq...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zhang Y,Geng X,Li Q,Xu J,Tan Y,Xiao M,Song J,Liu F,Fang C,Wang H

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a worsening of patients' quality of life. Appropriate management of skin t...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Fabbrocini G,Cameli N,Romano MC,Mariano M,Panariello L,Bianca D,Monfrecola G

更新日期：2012-05-28 00:00:00

abstract：:Gastric cancer, characterized by poor prognosis, remains a global health problem. Thus, it is important to describe the biological factors which can affect the prognosis in this disorder. The aim of our study was the determination of the relationship between apoptotic index (AI) and other clinicopathological features ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Jesionek-Kupnicka D,Tenderenda M,Rutkowski P

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:This study was designed to mainly evaluate the activity and safety of olanzapine compared with 5-hydroxytryptamine 3(5-HT3) receptor antagonists for prevention of chemotherapy-induced nausea and vomiting(CINV) in patients receiving highly or moderately emetogenic chemotherapy (HEC or MEC). The second goal wa...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Tan L,Liu J,Liu X,Chen J,Yan Z,Yang H,Zhang D

更新日期：2009-09-23 00:00:00

abstract：:Several models have been generated to estimate breast cancer risk and to predict the probability to identify a BRCA1 or BRCA2 germ line mutation. Each model, based on a slightly different study design and purpose, takes into account a definite number of relevant parameters and ultimately pertains to a specific cohort ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Pasini B,Casalis Cavalchini GC,Genovese T,Manoukian S

更新日期：2002-09-01 00:00:00

abstract：:In the original publication of this manuscript [1], Fig. 1 contained a typographical error ('Metabolic' incorrectly written as 'Metabolig'). ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Bosco MC,Orazi G,Del Bufalo D

更新日期：2020-02-24 00:00:00

abstract：:The present study assesses the adaptation of a group of female patients with either manifest or suspected breast cancer who have undergone Magnetic Resonance Imaging (MRI) after receiving psychological support. Several studies in literature have reported the effectiveness of such support in reducing anti-oxidant and d...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Caruso A,Bongiorno L,Vallini L,Russo P,Tomao F,Grandinetti ML

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Progranulin (PGRN), as a multifunctional growth factor, is overexpressed in multiple tumors, but the role of PGRN on tumor immunity is still unclear. Here, we studied the effect of PGRN on breast cancer tumor immunity and its possible molecular mechanism. METHODS:The changes of macrophage phenotypes after P...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Fang W,Zhou T,Shi H,Yao M,Zhang D,Qian H,Zeng Q,Wang Y,Jin F,Chai C,Chen T

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND:Colon cancer represents one of the leading causes of gastrointestinal tumors in industrialized countries, and its incidence appears to be increasing at an alarming rate. Accumulating evidence has unveiled the contributory roles of cancer stem cells (CSCs) in tumorigenicity, recurrence, and metastases. The fu...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Wang L,Guo J,Zhou J,Wang D,Kang X,Zhou L

更新日期：2020-10-28 00:00:00

abstract：:Axillary lymphadenectomy is a very important procedure in the staging of breast cancer patients. However, it is associated with a significant morbidity rate. On the other hand, using early diagnosis we can see a high number of cases where the lymph nodes are negatives. With the intention of avoiding unnecessary axilla...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zerwes FP,Frasson AL,Gutfilen B,Barbosa da Fonseca LM

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Despite the improvement of relapse-free survival mediated by anti-angiogenic drugs like sunitinib (Sutent®), or by combinations of anti-angiogenic drugs with immunotherapy, metastatic clear cell Renal Cell Carcinoma (mccRCC) remain incurable. Hence, new relevant treatments are urgently needed. The VEGFs core...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Dumond A,Brachet E,Durivault J,Vial V,Puszko AK,Lepelletier Y,Montemagno C,Pagnuzzi-Boncompagni M,Hermine O,Garbay C,Lagarde N,Montes M,Demange L,Grépin R,Pagès G

更新日期：2021-01-18 00:00:00

abstract：:Glutathione S-transferases (GSTs) are a group of enzymes involved in the detoxification process of carcinogens and other substances. The genes encoding isoenzymes M1 and T1 have "null" alleles, which are polymorphic in humans. Our purpose was to examine whether the GSTM1 and GSTT1 homozygous null genotypes have an imp...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Tsabouri SE,Georgiou I,Katsaraki A,Bourantas KL

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Enzymatically inactive chitinase-like protein CHI3L1 drives inflammatory response and promotes tumor progression. However, its role in gastric cancer (GC) tumorigenesis and metastasis has not yet been fully elucidated. We determined the significance of CHI3L1 expression in patients with GC. We also explored ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Geng B,Pan J,Zhao T,Ji J,Zhang C,Che Y,Yang J,Shi H,Li J,Zhou H,Mu X,Xu C,Wang C,Xu Y,Liu Z,Wen H,You Q

更新日期：2018-08-30 00:00:00

abstract：BACKGROUND:Agonistic CD40 antibodies have been demonstrated to activate antigen-presenting cells (APCs) and enhance antitumour T cell responses, thereby providing a new therapeutic option in cancer immunotherapy. In agonistic CD40 antibody-mediated inflammatory responses, a novel subset of E-cadherin + dendritic cells ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zhang Y,Hu X,Hu Y,Teng K,Zhang K,Zheng Y,Hong X,Yu K,Wang Y,Liu L

更新日期：2015-02-05 00:00:00

abstract：BACKGROUND:In this research, we aimed to resolve contradictory results whether SOX9 plays a positive or negative role in melanoma progression and determine whether SOX9 and its closely related member SOX10 share the same or distinct targets in mediating their functions in melanoma. METHODS:Immunofluorescence, TCGA dat...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Yang X,Liang R,Liu C,Liu JA,Cheung MPL,Liu X,Man OY,Guan XY,Lung HL,Cheung M

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:Colon cancer is invariably accompanied by altered coagulation activity; however, the precise role of phosphatidylserine (PS) in the hypercoagulable state of colon cancer patients remains unclear. We explored the exposure of PS on platelets and microparticles (MPs), and evaluate its role in procoagulant activ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zhao L,Bi Y,Kou J,Shi J,Piao D

更新日期：2016-03-25 00:00:00

abstract：:We evaluated the efficacy and toxicity profile of single-agent docetaxel administered in daily clinical practice at low-dose regimen in 37 pre-treated elderly patients with metastatic breast cancer previously exposed to chemotherapy. Docetaxel was employed by physician's preference according to a weekly (8 patients, 2...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Massacesi C,Marcucci F,Boccetti T,Battelli N,Pilone A,Rocchi MB,Bonsignori M

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:The association between striking life events, an important stress and acute anxiety disorder, and the occurrence of primary breast cancer is unclear. The current meta-analysis was designed to assess the relationship between striking life events and primary breast cancer incidence in women. METHODS:Systematic c...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Lin Y,Wang C,Zhong Y,Huang X,Peng L,Shan G,Wang K,Sun Q

更新日期：2013-08-13 00:00:00

abstract：:This retrospective study analyzed specifically the predicting factors for radioresponse and survival in 74 supratentorial astrocytoma patients. As a result of this study, cytoreduction in terms of ODs to T1 or T0 stage level or pre-RT T1 tumor stage along with radioresponse has a positive impact on long-term survival....

journal_title：Journal of experimental & clinical cancer research : CR

authors： Erkurt E,Tunali C,Erkişi M,Boyer B,Burgurt R

更新日期：1998-12-01 00:00:00

abstract：:Horseshoe kidney is a congenital anomaly of the upper urinary system frequently associated with atypical vascularization, mostly asymptomatic, usually undetected until the onset of infectious, obstructive or neoplastic complications. Although intravenous pyelography and US are useful tools, the role of CT is of vital ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Maccioni F,Stasolla A,D'Aprile MR,Binda B,Izzo L,Marini M

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Nerve-cancer interactions are increasingly recognized to be of paramount importance for the emergence and progression of pancreatic cancer (PCa). Here, we investigated the role of indirect cholinergic activation on PCa progression through inhibition of acetylcholinesterase (AChE) via clinically available ACh...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Pfitzinger PL,Fangmann L,Wang K,Demir E,Gürlevik E,Fleischmann-Mundt B,Brooks J,D'Haese JG,Teller S,Hecker A,Jesinghaus M,Jäger C,Ren L,Istvanffy R,Kühnel F,Friess H,Ceyhan GO,Demir IE

更新日期：2020-12-24 00:00:00

abstract：:Plant-derived phenolic compounds manifest many beneficial effects and can potentially inhibit several stages of carcinogenesis. In the present study, we investigated the efficacy of Emblica officinalis (E. officinalis) polyphenol fraction (EOP) on the induction of apoptosis in mouse and human carcinoma cell lineses an...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Rajeshkumar NV,Pillai MR,Kuttan R

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:To investigate influencing factors of the metastatic lymph nodes ratio (MLR) and whether it is related to survival in patients with gastric adenocarcinoma. METHODS:We retrospectively evaluated the clinical features of 121 patients with gastric adenocarcinoma enrolled in our hospital between 2000 and 2007. T...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Yu JW,Wu JG,Zheng LH,Zhang B,Ni XC,Li XQ,Jiang BJ

更新日期：2009-04-26 00:00:00

abstract：BACKGROUND:While treatment failure in cases of head and neck squamous cell carcinoma (HNSCC) frequently takes the form of locoregional recurrences and distant metastasis, our understanding of the mechanisms of metastasis in HNSCC is limited. We initially performed the upstream and key nodes analysis together with whole...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Hyakusoku H,Sano D,Takahashi H,Hatano T,Isono Y,Shimada S,Ito Y,Myers JN,Oridate N

更新日期：2016-01-12 00:00:00

abstract：BACKGROUND:Ovarian cancer (OC) is the most lethal gynecological malignancy and the second leading cause of cancer-related death in women. Treatment with PARP inhibitors (PARPi), such as Olaparib, has been recently introduced for OC patients, but resistance may occur and underlying mechanisms are still poorly understood...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Vescarelli E,Gerini G,Megiorni F,Anastasiadou E,Pontecorvi P,Solito L,De Vitis C,Camero S,Marchetti C,Mancini R,Benedetti Panici P,Dominici C,Romano F,Angeloni A,Marchese C,Ceccarelli S

更新日期：2020-01-02 00:00:00

abstract：:In the present study we report twenty-nine patients with iatrogenic injuries and management during various operations for malignant conditions. The patients were reviewed in order to identify and study the incidence, type of treatment administered and outcome. The study group was composed of 29 patients with 31 iatrog...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Berkmen F,Peker AE,Alagöl H,Ayyildiz A,Arik AI,Başay S

更新日期：2000-12-01 00:00:00