Density and size of lymphoid follicles are useful clues in differentiating primary intestinal follicular lymphoma from intestinal reactive lymphoid hyperplasia.

abstract：BACKGROUND:Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets prior to definitive treatment is gaining importance in clinical practice. In this study, we investiga...

journal_title：Diagnostic pathology

authors： Lo RC,Leung CO,Chok KS,Ng IO

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Choriocarcinoma is a highly aggressive, malignant trophoblastic neoplasm that can be gestational or non-gestational in origin. Accurate discrimination between these two subtypes, the causative pregnancy type, and the pregnancy-to-treatment interval for gestational choriocarcinoma are vital for clinical manag...

journal_title：Diagnostic pathology

authors： Zhang X,Yan K,Chen J,Xie X

更新日期：2019-08-17 00:00:00

abstract：BACKGROUND:Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract, which originates from mesonephric duct remnants. Its diagnosis is pathologically challenging, because MNAC may exhibit a mixture of morphological patterns that complicates the differential diagnosis. CASE PRESENTATION:The patient...

journal_title：Diagnostic pathology

authors： Montalvo N,Redrobán L,Galarza D

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:The transcriptional co-activator, TAZ, is an important effector of the Hippo pathway and is critical for the development of human cancers. However, the expression and prognostic significance of TAZ in retinoblastoma is currently unclear. METHODS:TAZ expression was examined in 43 retinoblastoma samples by im...

journal_title：Diagnostic pathology

authors： Zhang Y,Xue C,Cui H,Huang Z

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression. MAIN BODY:It ...

journal_title：Diagnostic pathology

authors： Abbaszadegan MR,Keyvani V,Moghbeli M

更新日期：2019-08-31 00:00:00

abstract：BACKGROUND:The feasibility of evaluating an objective grading of cervical intraneoplasia lesions (CIN) is attempted using an automatic computerized system able to measure several valuable parameters with special reference to epithelium differentiation. METHODS:4 groups of 10 images each were selected at random from 68...

journal_title：Diagnostic pathology

authors： Jondet M,Agoli-Agbo R,Dehennin L

更新日期：2010-01-22 00:00:00

abstract：BACKGROUND:The microRNAs present a class of non-coding RNAs which are usually implicated in tumor biology. Recent report has unraveled that a novel member of microRNA family called miR-1246. However, the functional role and molecular mechanisms of miR-1246 in non-small cell lung cancer (NSCLC) is still elusive. METHOD...

journal_title：Diagnostic pathology

authors： Huang W,Li H,Luo R

更新日期：2015-07-25 00:00:00

abstract：BACKGROUND:Morphine has been widely used as a clinical anesthetic and analgesic. However, abuse of morphine might result in psychological and physiological dependence. Previous studies have indicated that memory mechanisms play critical roles in morphine dependence. METHODS:Morphine dependence was established in mice ...

journal_title：Diagnostic pathology

authors： Ye J,Yang Z,Li C,Cai M,Zhou D,Zhang Q,Wei Y,Wang T,Liu Y

更新日期：2014-07-10 00:00:00

abstract：:Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis. The majority are treated by aggressive curettage or resection. Vascular invasion outside the boundary of the tumor can be seen. Metastas...

journal_title：Diagnostic pathology

authors： Miller IJ,Blank A,Yin SM,McNickle A,Gray R,Gitelis S

更新日期：2010-09-22 00:00:00

abstract：BACKGROUND:Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as "Clear cell sarcoma-like tumor of the gastrointestinal tract". It shares some of the histological features of clear cell sarcoma (CCS) but lacks the immunohistochemical r...

journal_title：Diagnostic pathology

authors： Alyousef MJ,Alratroot JA,ElSharkawy T,Shawarby MA,Al Hamad MA,Hashem TM,Alsayyah A

更新日期：2017-03-20 00:00:00

abstract：UNLABELLED:Gastroenteropancreatic neuroendocrine tumors are the most incident neuroendocrine tumors. In the new WHO classification (2010) the embryological derivation of each neoplastic entity is one of the most important parameters. Gangliocytic Paraganglioma is a tumor originating in the hindgut, a rare neoplasm, gen...

journal_title：Diagnostic pathology

authors： Tatangelo F,Cantile M,Pelella A,Losito NS,Scognamiglio G,Bianco F,Belli A,Botti G

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:Patients with pathologic stage (p-Stage) IA non-small cell lung cancer (NSCLC) have a good survival rate because of possible curative resection. However, up to 10% of these patients relapse postoperatively. To identify unfavorable prognostic factors, we retrospectively analyzed the clinicopathological featur...

journal_title：Diagnostic pathology

authors： Hamanaka R,Yokose T,Sakuma Y,Tsuboi M,Ito H,Nakayama H,Yamada K,Masuda R,Iwazaki M

更新日期：2015-04-02 00:00:00

abstract：UNLABELLED:We report a case of recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) in a 57-year-old male. The patient presented with papules and pruritus of the lower limbs of more than 1 month duration, and with angioedema and intensively pruritic, necrotizing lesions of the bilateral anterior tibias and f...

journal_title：Diagnostic pathology

authors： Li W,Cao W,Song H,Ciu Y,Lu X,Zhang F

更新日期：2013-11-07 00:00:00

abstract：BACKGROUND:Transbronchial needle aspiration (TBNA) is a minimally invasive procedure performed to diagnose lymph node (LN) adenopathy. TBNA with and without endobronchial ultrasound (EBUS) guidance has a high diagnostic yield for malignant LN enlargement, but the value for diagnosing benign LN enlargement has been less...

journal_title：Diagnostic pathology

authors： Shen H,Lou L,Chen T,Zou Y,Wang B,Xu Z,Ye Q,Shen H,Li W,Xia Y

更新日期：2020-04-15 00:00:00

abstract：:Primary involvement of skeletal muscle is a very rare event in ALK-1 positive anaplastic large cell lymphoma (ALCL). We describe a case of a 10-year old boy presenting with a three week history of pain and a palpable firm swelling at the dorsal aspect of the left thigh. Histological examination of the lesion revealed ...

journal_title：Diagnostic pathology

authors： Gaiser T,Geissinger E,Schattenberg T,Scharf HP,Dürken M,Dinter D,Rosenwald A,Marx A

更新日期：2012-04-12 00:00:00

abstract：INTRODUCTION:Nemaline myopathy is a rare genetic muscle disorder defined by the presence of nemaline rods in the muscle fibre sarcoplasm. Congenital nemaline myopathy is the most serious form of the disease's spectrum. CASE PRESENTATION:The affected newborn has no spontaneous movement, fractures at birth and respirato...

journal_title：Diagnostic pathology

authors： Waisayarat J,Suriyonplengsaeng C,Khongkhatithum C,Rochanawutanon M

更新日期：2015-04-16 00:00:00

abstract：BACKGROUND:In recent years, a battery-powered bone marrow biopsy system was developed and cleared by the U.S. Food and Drug Administration to allow health care providers to access the bone marrow space quickly and efficiently. A multicenter randomized clinical trial was designed for adult patients to determine if the p...

journal_title：Diagnostic pathology

authors： Berenson JR,Yellin O,Blumenstein B,Bojanower D,Croopnick J,Aboulafia D,Upadhyaya G,Spadaccini C

更新日期：2011-03-23 00:00:00

abstract：BACKGROUND:To evaluate the clinical utility of LIM Domain Only 2 (LMO2) negative and CD38 positive in diagnosis of Burkitt lymphoma (BL). METHODS:LMO2 and CD38 expression determined by immunohistochemistry in 75 BL, 12 High-grade B-cell lymphoma, NOS (HGBL,NOS) and 3 Burkitt-like lymphomas with the 11q aberration. RE...

journal_title：Diagnostic pathology

authors： Liu Y,Bian T,Zhang Y,Zheng Y,Zhang J,Zhou X,Xie J

更新日期：2019-09-04 00:00:00

abstract：BACKGROUND:Appendiceal parasites can cause symptoms of appendiceal pain, independent of microscopic evidence of acute inflammation. The diagnosis of a parasitic infestation is generally achieved only after the pathologic examination of the resected appendices. PATIENTS/METHODS:Pathology department records were reviewe...

journal_title：Diagnostic pathology

authors： Aydin O

更新日期：2007-05-24 00:00:00

abstract：BACKGROUND:Gliomas are aggressive tumors of the central nervous system that rely on production of growth factors for tumor progression. Interleukin 8 (IL-8) is up-regulated in gliomas to promote angiogenesis and proliferation. The aim of this study was to evaluate the association of the IL-8 -251 T/A and +781 C/T polym...

journal_title：Diagnostic pathology

authors： Liu H,Mao P,Xie C,Xie W,Wang M,Jiang H

更新日期：2015-08-07 00:00:00

abstract：:This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anapla...

journal_title：Diagnostic pathology

authors： Grayson W,Pantanowitz L

更新日期：2008-07-25 00:00:00

abstract：OBJECTIVES:Non-Hodgkin's lymphoma (NHL) primarily derived from the base of the tongue, is rare. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are important aetiological risk factors for tumours of the head and neck. This study describes the clinicopathological features of NHL in the tongue base and the status...

journal_title：Diagnostic pathology

authors： Ren X,Cheng Y,Wu S,Zeng X,Shi X,Ling Q,Li Z,Liang Z,Wang B

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) is one of the most powerful genetic analysis tools for pathological diagnoses. FISH can detect various genetic abnormalities including gene translocation that was specifically found in translocation-related sarcomas (TRSs). Here, we report the use of FISH in expert r...

journal_title：Diagnostic pathology

authors： Sugita S,Asanuma H,Hasegawa T

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:Maspin is a unique member of the serine protease inhibitor superfamily and its expression is found in myoepithelial cells of normal mammary glands; therefore, it has been considered to be a myoepithelial marker. We previously reported that maspin was frequently expressed in biologically aggressive breast can...

journal_title：Diagnostic pathology

authors： Umekita Y,Ohi Y,Souda M,Rai Y,Sagara Y,Sagara Y,Tamada S,Tanimoto A

更新日期：2011-04-16 00:00:00

abstract：BACKGROUND:Previous studies suggested that apolipoprotein A5 (ApoA5) genetic polymorphisms (SNPs) may result in lipid metabolism disorders. Therefore, genetic polymorphisms in ApoA5 may be associated with the occurrence of osteonecrosis of femoral head (ONFH). METHODS:We designed a case-control study including 223 pat...

journal_title：Diagnostic pathology

authors： Cui Y,Kaisaierjiang A,Cao P,Wu ZY,Lv Q

更新日期：2014-12-17 00:00:00

abstract：:Diagnostic surgical pathology or tissue–based diagnosis still remains the most reliable and specific diagnostic medical procedure. The development of whole slide scanners permits the creation of virtual slides and to work on so-called virtual microscopes. In addition to interactive work on virtual slides approaches ha...

journal_title：Diagnostic pathology

authors： Kayser K,Görtler J,Borkenfeld S,Kayser G

更新日期：2011-01-01 00:00:00

abstract：:Primary neoplasms of the mesentery are very rare. They are usually of mesenchymal origin and include desmoid tumor, lipoma, liposarcoma, and fibrosarcoma. Metastatic carcinomas and lymphoma are more common. We report a rare case of localized mesenteric Castleman's disease, presenting as intestinal obstruction. Clinica...

journal_title：Diagnostic pathology

authors： El Demellawy D,Herath C,Truong F,Nasr A,Alowami S

更新日期：2009-12-04 00:00:00

abstract：BACKGROUND:Identification of predictive molecular alterations in lung adenocarcinoma is essential for accurate therapeutic decisions. Although several molecular approaches are available, a number of issues, including tumor heterogeneity, frequent material scarcity, and the large number of loci to be investigated, must ...

journal_title：Diagnostic pathology

authors： Bonaparte E,Pesenti C,Fontana L,Falcone R,Paganini L,Marzorati A,Ferrero S,Nosotti M,Mendogni P,Bareggi C,Sirchia SM,Tabano S,Bosari S,Miozzo M

更新日期：2018-01-12 00:00:00

abstract：BACKGROUND:Hypermethylation of the promoter region of the RAS association domain family 1A gene (RASSF1A) occurs widely in hepatocellular carcinoma (HCC) tissues. While the diagnostic performance of the use of RASSF1A methylation as a serum or plasma marker in patients with HCC has varied largely in the literature,we c...

journal_title：Diagnostic pathology

authors： Dong X,He H,Zhang W,Yu D,Wang X,Chen Y

更新日期：2015-08-04 00:00:00

abstract：OBJECTIVES:RAD51 gene plays an important role in the pathogenesis of squamous cell carcinoma of the head and neck (SCCHN), colorectal cancer, ovarian cancer and acute leukaemia. A number of studies assessed the association between RAD51 135G/C polymorphism and the risk of these cancers in different population. However,...

journal_title：Diagnostic pathology

authors： Cheng D,Shi H,Zhang K,Yi L,Zhen G

更新日期：2014-01-23 00:00:00