Correlation between UGT1A1 gene polymorphism and irinotecan chemotherapy in metastatic colorectal cancer: a study from Guangxi Zhuang.

abstract：BACKGROUND:Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evaluate the association of HPV and HIV status, p16 expression level and TP53 mutations with the absence ...

journal_title：BMC gastroenterology

authors： Soares PC,Abdelhay ES,Thuler LCS,Soares BM,Demachki S,Ferro GVR,Assumpção PP,Lamarão LM,Ribeiro Pinto LF,Burbano RMR

更新日期：2018-02-21 00:00:00

abstract：BACKGROUND:To exam the biochemical, obstetric management and pregnancy outcome in women with intrahepatic cholestasis of pregnancy (ICP) and treatment with ursodeoxycholic acid (UDCA). METHODS:Pregnancy outcome in patients with ICP (N = 307) was studied and patients treated with UDCA (N = 208) vs. no UDCA were compare...

journal_title：BMC gastroenterology

authors： Joutsiniemi T,Timonen S,Linden M,Suvitie P,Ekblad U

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Apoptosis inhibitor of macrophage (AIM) and adipocytokines are involved in the metabolic syndrome, which has been putatively associated with the progression of chronic hepatitis C (CHC). However, the association between these cytokines and CHC is not fully elucidated. The aim of this study is to test whether...

journal_title：BMC gastroenterology

authors： Mera K,Uto H,Mawatari S,Ido A,Yoshimine Y,Nosaki T,Oda K,Tabu K,Kumagai K,Tamai T,Moriuchi A,Oketani M,Shimada Y,Hidaka M,Eguchi S,Tsubouchi H

更新日期：2014-02-13 00:00:00

abstract：BACKGROUND:The aim of this study was to develop and psychometrically test a short, patient-reported questionnaire to be used in clinical practice for patients with Irritable Bowel Syndrome (IBS). The Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) questionnaire was designed to measure the treatment respons...

journal_title：BMC gastroenterology

authors： Bengtsson M,Ohlsson B,Ulander K

更新日期：2007-05-03 00:00:00

abstract：BACKGROUND:Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of this study is to investigate real life results in using oral 5-ASA products for maintaining mild to mo...

journal_title：BMC gastroenterology

authors： Nagahori M,Kochi S,Hanai H,Yamamoto T,Nakamura S,Omuro S,Watanabe M,Hibi T,OPTIMUM Study Group.

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is common, with surgery as the main curative treatment. The prevalence of chronic liver disease has increased, but knowledge is limited on postoperative mortality in patients with liver disease who undergo CRC surgery. Hence, we examined 30-day mortality after CRC surgery in patients ...

journal_title：BMC gastroenterology

authors： Montomoli J,Erichsen R,Christiansen CF,Ulrichsen SP,Pedersen L,Nilsson T,Sørensen HT

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:Signet ring cell carcinoma of the colon and rectum is rare, and most cases are detected at an advanced stage. We present a case of primary signet ring cell carcinoma detected at an early stage by magnifying endoscopy with narrow-band imaging (NBI) and crystal violet staining. CASE PRESENTATION:A 73-year-old...

journal_title：BMC gastroenterology

authors： Ohnita K,Isomoto H,Akashi T,Hashiguchi K,Matsushima K,Minami H,Akazawa Y,Yamaguchi N,Takeshima F,To K,Takeshita H,Yasui H,Abe K,Nakao K

更新日期：2015-07-24 00:00:00

abstract：BACKGROUND:Pegylated interferon (PEG-IFN) alfa-2b is recommended for chronic hepatitis B (CHB). We aimed to investigate the sustainability of off-treatment responses among Chinese HBeAg-positive CHB patients treated with PEG-IFN alfa-2b from a randomized trial. METHODS:Eligible Chinese patients (n = 322) were followed...

journal_title：BMC gastroenterology

authors： Sun J,Ding H,Chen G,Wang G,Wei L,Zhang J,Xie Q,Wan M,Tang H,Chen S,Gao Z,Wang Y,Zhang D,Huang W,Sheng J,Ning Q,Yang D,Lu J,Pan C,Yang Y,Wang J,Sun C,Wang Q,Hou J

更新日期：2019-05-02 00:00:00

abstract：BACKGROUNDS:Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in Asians. However, data on prevalence and factors associated with NAFLD in Asians are lacking. The aim of this study is to investigate the prevalence of NAFLD in Shanghai employees to assess the relationship between N...

journal_title：BMC gastroenterology

authors： Hu X,Huang Y,Bao Z,Wang Y,Shi D,Liu F,Gao Z,Yu X

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:We examined the intrinsic hepatic innervation after partial hepatectomy (PH) in rats and the presence and pattern of neural sprouting in regenerating liver. METHODS:Male Wistar rats (age 9-13 weeks-w, weight 204-356 g), were submitted to two-thirds PH. Rats were sacrificed at postoperative days (d) 1, 3, 5,...

journal_title：BMC gastroenterology

authors： Kandilis AN,Koskinas J,Vlachos I,Skaltsas S,Karandrea D,Karakitsos P,Pantopoulou A,Palaiologou M,Nikiteas N,Tiniakos DG,Perrea DN

更新日期：2014-11-25 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with cholestasis as principal symptom. CASE PRESENTATION:A 43-year-old caucasian man was admitted to our hosp...

journal_title：BMC gastroenterology

authors： Gallerani M,Pala M,Fabbian F,De Giorgi A

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Endothelial nitric oxide synthase (eNOS) has previously been detected in the glandular part of the human gastric mucosa. Furthermore, nitric oxide (NO) has been shown to influence gastric secretion in various animal models. The present study was conducted to investigate the influence of exogenously and endog...

journal_title：BMC gastroenterology

authors： Berg A,Redeen S,Ericson AC,Sjöstrand SE

更新日期：2004-08-06 00:00:00

abstract：BACKGROUND:Vitamin K deficiency results in serious coagulation dysfunction, but hemorrhagic shock is rare. Herein, we describe a case of vitamin K deficiency and abnormality in the path of the intercostal artery, the combination of which led to hemorrhagic shock. CASE PRESENTATION:An 83-year-old woman was hospitalized...

journal_title：BMC gastroenterology

authors： Itagaki H,Hagino T

更新日期：2019-04-18 00:00:00

abstract：BACKGROUND:Endoscopic nasobiliary drainage (ENBD) is widely used for biliary decompression in patients with biliary disease. However, it is difficult to reposition a nasobiliary catheter from the mouth to nostril. We developed a new device, which has a curved flexible loop and bar-handle, for repositioning of ENBD cath...

journal_title：BMC gastroenterology

authors： Choi SJ,Lee JM,Choi HS,Kim ES,Keum B,Seo YS,Jeen YT,Lee HS,Chun HJ,Um SH,Kim CD,Oh CH

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is commonly associated with a disturbance of glucose metabolism. However, there have been conflicting reports on whether the clearance of the HCV may be followed by changes of serum blood glucose and insulin resistance. The aim of the present study was to evaluate the impact...

journal_title：BMC gastroenterology

authors： Li Y,Wang X,Yu G,Sun H,Lv J,Chi X,Wu R,Gao X,Niu J

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) symptoms often overlap. In some IBS cases there are subtle inflammatory changes similar to the immune-mediated pathophysiology of IBD, and the risk of both increases after infectious gastroenteritis (IGE). METHODS:To evaluate the effect of ...

journal_title：BMC gastroenterology

authors： Porter CK,Cash BD,Pimentel M,Akinseye A,Riddle MS

更新日期：2012-05-28 00:00:00

abstract：BACKGROUND:A variety of extra-intestinal manifestations (EIMs), including hepatobiliary complications, are associated with inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) have been shown to play a potential role in the therapy of IBD. This study was designed to investigate the effect and mechanism of MS...

journal_title：BMC gastroenterology

authors： Niu GC,Liu L,Zheng L,Zhang H,Shih DQ,Zhang X

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:Controversy exists regarding the role of PD1 and its ligand PD-L1 in chronic hepatitis B infection. In some studies, persistent HBV infection has been attributed to high levels of PD-1 and PD-L1 expression on HBV-specific T-cells and antigen-presenting cells (APCs) respectively. Other studies revealed that t...

journal_title：BMC gastroenterology

authors： Wenjin Z,Chuanhui P,Yunle W,Lateef SA,Shusen Z

更新日期：2012-08-16 00:00:00

abstract：BACKGROUND:In diagnosing celiac disease (CD), serological tests are highly valuable. However, their role in following up children with CD after prescription of a gluten-free diet is unclear. This study aimed to compare the performance of antibody tests in predicting small-intestinal mucosal status in diagnosis vs. foll...

journal_title：BMC gastroenterology

authors： Vécsei E,Steinwendner S,Kogler H,Innerhofer A,Hammer K,Haas OA,Amann G,Chott A,Vogelsang H,Schoenlechner R,Huf W,Vécsei A

更新日期：2014-02-13 00:00:00

abstract：BACKGROUND:Acute pancreatitis (AP) is associated with considerable morbidity and mortality. Current severity scores include multiple variables and some of them are only complete within 48 h of admission. Red cell distribution width (RDW) is a simple and routine parameter that seems to be related to inflammatory status....

journal_title：BMC gastroenterology

authors： Gravito-Soares M,Gravito-Soares E,Gomes D,Almeida N,Tomé L

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The association between proinflammatory cytokine gene polymorphisms and gastric diseases related to Helicobacter pylori varies by population and geographic area.Our objective was to determine if the IL-1B -511 T>C and -31 C>T polymorphisms and H. pylori vacA genotypes are associated with risk of chronic gast...

journal_title：BMC gastroenterology

authors： Martínez-Carrillo DN,Garza-González E,Betancourt-Linares R,Mónico-Manzano T,Antúnez-Rivera C,Román-Román A,Flores-Alfaro E,Illades-Aguiar B,Fernández-Tilapa G

更新日期：2010-10-27 00:00:00

abstract：BACKGROUND:Distal diminutive colorectal polyps are common and accurate endoscopic prediction of hyperplastic or adenomatous polyp histology could reduce procedural time, costs and potential risks associated with the resection. Within this study we assessed whether digital chromoendoscopy can accurately predict the hist...

journal_title：BMC gastroenterology

authors： Rath T,Tontini GE,Nägel A,Vieth M,Zopf S,Günther C,Hoffman A,Neurath MF,Neumann H

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Aim was to explore the association of ERCC1 and TS mRNA levels with the disease free survival (DFS) in Chinese colorectal cancer (CRC) patients receiving oxaliplatin and 5-FU based adjuvant chemotherapy. METHODS:Total 112 Chinese stage II-III CRC patients were respectively treated by four different chemothe...

journal_title：BMC gastroenterology

authors： Li S,Zhu L,Yao L,Xia L,Pan L

更新日期：2014-08-29 00:00:00

abstract：BACKGROUND:Helicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patients with H. pylori infection. CASE PRESENTATION:We report a patient with PGL in whom the tumor regressed after...

journal_title：BMC gastroenterology

authors： Ghoshal UC,Guha D,Bandyopadhyay S,Pal C,Chakraborty S,Ghoshal U,Ghosh TK,Pal BB,Banerjee PK

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Previous research has shown variation in the effects of patient factors, including hepatic necroinflammatory activity, on liver stiffness measurement (LSM). This prospective study attempts to identify explanatory factors for LSM in patients with chronic hepatitis C (CHC) using acoustic radiation force impuls...

journal_title：BMC gastroenterology

authors： Chen SH,Li YF,Lai HC,Kao JT,Peng CY,Chuang PH,Su WP,Chiang IP

更新日期：2012-08-10 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the pathophysiological mechanisms that cause these individual differences in clinical presentation remain largely unknown. In consequence, IBD is current...

journal_title：BMC gastroenterology

authors： Imhann F,Van der Velde KJ,Barbieri R,Alberts R,Voskuil MD,Vich Vila A,Collij V,Spekhorst LM,Van der Sloot KWJ,Peters V,Van Dullemen HM,Visschedijk MC,Festen EAM,Swertz MA,Dijkstra G,Weersma RK

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Tumor-to-tumor metastasis is a rare event. Rectal cancer to primary thyroid neoplasm metastasis is extremely rare. Herein, we reported a case of metastatic rectal adenocarcinoma to a papillary thyroid carcinoma. The incidence and clinicopathological characteristics of metastatic colorectal cancer to a thyroi...

journal_title：BMC gastroenterology

authors： Luo M,Huang Y,Li Y,Zhang Y

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:Leukocytoclastic vasculitis (LCV) is an immune-complex mediated vasculitis characterized by neutrophilic inflammation and nuclear debris in post capillary venules. LCV is a rare dermatologic manifestation of Crohn's disease (CD) and may occur with the onset of the disease or any time after the diagnosis incl...

journal_title：BMC gastroenterology

authors： Buck M,Dumic I,McDermott W,Nordstrom C,Dawan S,Virata A,Martin S,Hudson A,Milovanovic T,Nordin T

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:Studies on Epstein-Barr virus (EBV) have focused mostly on neoplastic disease. Few studies have considered immunocompetent patients who are not severely immunocompromised. Liver cirrhosis is associated with various levels of immune dysfunction. In the current study, we determined EBV infection rates, the inf...

journal_title：BMC gastroenterology

authors： Hu J,Zhang X,Yu G,Cai H,Gu J,Hu M,Xiang D,Lian J,Yu L,Jia H,Zhang Y,Yang Y

更新日期：2019-06-18 00:00:00

abstract：BACKGROUND:Diminished bone mineral density (BMD) is of significant concern in pediatric inflammatory bowel disease (IBD). Exact etiology is debatable. The recognition of fibroblast growth factor 23 (FGF23), a phosphaturic hormone related to tumor necrosis factor alpha (TNF-α) makes it plausible to hypothesize its possi...

journal_title：BMC gastroenterology

authors： El-Hodhod MA,Hamdy AM,Abbas AA,Moftah SG,Ramadan AA

更新日期：2012-05-02 00:00:00