Adrenopause: an imbalance between dehydroepiandrosterone (DHEA) and cortisol secretion.

abstract：:Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TS...

journal_title：Journal of endocrinological investigation

authors： Luster M,Hänscheid H,Freudenberg LS,Verburg FA

更新日期：2012-01-01 00:00:00

abstract：:During diabetic ketoacidosis, in 17 adult patients, significant decreases in serum TBG and total T4 levels were observed, without significant alteration of the T4 to TBG binding property. In addition, serum free T4 (FT4) was moderately elevated and the TSH response to TRH was markedly blunted. No correlation, however,...

journal_title：Journal of endocrinological investigation

authors： Glinoer D,Naeije R,Golstein J,Fernandez-Deville M,Vanhaelst L

更新日期：1980-01-01 00:00:00

abstract：:Vitamin D via its receptor has essential actions on parathyroid cells, inhibiting PTH secretion, and parathyroid cell proliferation. While the effects of vitamin D depletion in the pathogenesis of secondary hyperparathyroidism in elderly individuals or in the occurrence of parathyroid hyperplasia in patients with rena...

journal_title：Journal of endocrinological investigation

authors： Nuti R,Merlotti D,Gennari L

更新日期：2011-07-01 00:00:00

abstract：UNLABELLED:The aim of this study was to assess the behaviour of insulin sensitivity and insulin resistance (IR) indexes in a group of obese adolescents with Type 2 diabetes mellitus (T2DM) in comparison to obese adolescents without diabetes and normal controls, moreover to compare these parameters with the cardiac auto...

journal_title：Journal of endocrinological investigation

authors： Cerutti F,Rabbia F,Rabbone I,Bobbio A,Ignaccolo MG,Greco G,Bertello MC,Mulatero P,Veglio F,Pacini G

更新日期：2010-09-01 00:00:00

abstract：:Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literat...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Grimaldi P,Cocco R,Garibotto G,Ferrini S,Giordano G

更新日期：1979-07-01 00:00:00

abstract：:Aim of the study was to compare urinary galactosyl-hydroxylysine (GHyl), deoxypyridinoline (D-Pyr) and pyridinoline (Pyr) before and after 5 to 9 months of hormone replacement therapy (HRT) in postmenopausal women. The urinary markers were measured by HPLC in the second void of fasting samples and were expressed as ra...

journal_title：Journal of endocrinological investigation

authors： Marabini R,Sirtori P,Chionna R,Barzizza L,Rubinacci A

更新日期：1996-03-01 00:00:00

abstract：:Cardiovascular problems have long been recognized as responsible for an increased morbidity and mortality in patients with acromegaly. The aim of the present study was to evaluate echocardiographically the prevalence of cardiomyopathy in a cohort of acromegalic patients and to analyze the results in relation to demogr...

journal_title：Journal of endocrinological investigation

authors： Terzolo M,Avonto L,Matrella C,Pozzi R,Luceri S,Borretta G,Pecchio F,Ugliengo G,Magro GP,Reimondo G

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:One of the major topics in modern societies is the study of relationships between diet, stress and incidence of metabolic disorders. AIM:This study aimed to investigate possible impairment in glucose-stimulated insulin secretion induced by a high-fat (cow intra-abdominal fat) diet in response to acute stres...

journal_title：Journal of endocrinological investigation

authors： Ghalami J,Zardooz H,Rostamkhani F,Farrokhi B,Hedayati M

更新日期：2013-11-01 00:00:00

abstract：:Exhaustive graded exercise leads to changes of hormones, carbohydrate, and lipid metabolism in normal controls and obese patients after prolonged starvation. Concomitant with a large increase of plasma catecholamines, insulin concentration is reduced and blood glucose levels slowly increase. More glucose is made avail...

journal_title：Journal of endocrinological investigation

authors： Jakober B,Schmülling RM,Müller PH,Eggstein M

更新日期：1983-12-01 00:00:00

abstract：:Ketoacidosis is a metabolic alteration caused by absolute or relative insulin deficiency and oversecretion of glucagon. Prompt diagnosis and rapid initiation of treatment are mandatory to avoid the complications and fatal outcome. Reduction of plasma glucose to levels within acceptable limits, block of ketogenesis, re...

journal_title：Journal of endocrinological investigation

authors： Reitano G

更新日期：1989-01-01 00:00:00

abstract：:Non-classical congenital adrenal hyperplasia (NCAH) is a morbid condition sustained by the reduced function of one of the enzymes involved in the adrenal steroid biosynthesis pathway, mainly the 21-hydroxylase. Different degrees of enzyme activity impairment determine different clinical pictures, with childhood or pos...

journal_title：Journal of endocrinological investigation

authors： Einaudi S,Napolitano E,Restivo F,Motta G,Baldi M,Tuli G,Grosso E,Migone N,Menegatti E,Manieri C

更新日期：2011-10-01 00:00:00

abstract：:Effects of primary hypothyroidism (HYPO) on the male gonadal axis are controversial, with only scanty data on the gonadotroph cell response and no information on GnRH tuberoinfundibular neurons, even in animal models. HYPO has been reported to variably induce hypogonadotropic hypogonadism, a hypergonadotropic state, o...

journal_title：Journal of endocrinological investigation

authors： Toni R,Della Casa C,Castorina S,Cocchi D,Celotti F

更新日期：2005-01-01 00:00:00

abstract：:It has previously been suggested that ghrelin mediates GH-independent biologic activities on the heart. We investigated the acute effects on cardiac contraction of a single iv administration of human ghrelin (in a dose of 1 microg/kg) in severe untreated GH deficient subjects. Prior to the ghrelin infusion, an echocar...

journal_title：Journal of endocrinological investigation

authors： Janssen JA,Poldermans D,Hofland LJ,Vourvouri EC,Muller AF,Bax JJ,Deghenghi R,Broglio F,Ghigo E,van der Lely AJ

更新日期：2004-07-01 00:00:00

abstract：:The aim of this paper is to briefly review some practical aspects of the relationship between thyroid function and several disorders of the hemostatic system in terms of bleeding and thrombosis. Thrombocytopenia, acquired hemophilia, hypercoagulability, cardioembolism and other biochemical coagulative and fibrinolytic...

journal_title：Journal of endocrinological investigation

authors： Marongiu F,Cauli C,Mariotti S

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:Although vitamin D is reportedly associated with various cancers, the association between vitamin D and thyroid cancer is indefinite. We aimed to investigate whether this association applies to thyroid cancer (TC). METHODS:A total of 276 Chinese Han people were recruited in a current matched case-control study...

journal_title：Journal of endocrinological investigation

authors： Hu MJ,Zhang Q,Liang L,Wang SY,Zheng XC,Zhou MM,Yang YW,Zhong Q,Huang F

更新日期：2018-10-01 00:00:00

abstract：:Here we describe a subject with congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21-CAH), in its classical virilizing form, who presented at birth ambiguous genitalia and subsequently was assigned by the parents as male. At the age of 8 years, he underwent a two-step surgical correction of hypospadia a...

journal_title：Journal of endocrinological investigation

authors： Valentino R,Savastano S,Tommaselli AP,Dorato M,Scarpitta MT,Calvanese E,Del Puente A,Lombardi G

更新日期：2000-05-01 00:00:00

abstract：:The present study was designed to assess the transfer of thyroglobulin (Tg) and anti-Tg antibodies (TgAb) to saliva in subjects with positive TgAb in their sera. Group I consisted of normal euthyroid control subjects (n = 10). Group II were patients with various thyroid disorders and no TgAb in their sera (n = 6). Gro...

journal_title：Journal of endocrinological investigation

authors： Van Herle AJ,Rosenblit PD,Van Herle TL,Van Herle P,Greipel M,Kellett K

更新日期：1989-03-01 00:00:00

abstract：:In 1939 Alan Turing, a major scholar in the field of mechanical computation, described a system whose computational power was beyond that of a discrete, finite state machine (Turing Machine). The composition of this system was likely the first example of what is now called an hybrid computational system. Since then, d...

journal_title：Journal of endocrinological investigation

authors： Sandri G

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1DM) is an autoimmune disease in which both genetic and environmental factors play a role in the etiology. AIM:The aim of this study was to analyze the incidence of T1DM. METHODS:A retrospective technique was used to register all newly diagnosed cases of T1DM in Belgrade (Serbia) children...

journal_title：Journal of endocrinological investigation

authors： Sipetic S,Maksimovic J,Vlajinac H,Ratkov I,Sajic S,Zdravkovic D,Sipetic T

更新日期：2013-05-01 00:00:00

abstract：:Our aim was to investigate the effect of GnRH-agonist (GnRH-a) induced suppression of plasma sex steroids on serum GH, insulin like growth factor-I (IGF-I) and insulin levels after an oral glucose load (OGTT) in women with polycystic ovary syndrome (PCOS). Serum insulin, GH and IGF-I levels during a 75-g 4-h OGTT were...

journal_title：Journal of endocrinological investigation

authors： Tropeano G,Liberale I,Vuolo IP,Barini A,Caroli G,Carfagna P,Menini E

更新日期：1997-04-01 00:00:00

abstract：:The effect of an oral dose of 200 or 400 mg sodium valproate (DPA) on ACTH and cortisol secretion was assessed in 11 patients with Cushing's disease (3 bilaterally adrenalectomized), 3 patients with Nelson's syndrome and 6 patients with Addison's disease. In none of the patients examined DPA induced changes in ACTH (a...

journal_title：Journal of endocrinological investigation

authors： Loli P,Berselli ME,Frascatani F,Muratori F,Tagliaferri M

更新日期：1984-04-01 00:00:00

abstract：PURPOSE:Interleukin (IL)-8 is a proinflammatory C-X-C chemokine involved in inflammation underling cardiac diseases, primary or in comorbid condition, such diabetic cardiomyopathy (DCM). The phosphodiesterase type 5 inhibitor sildenafil can ameliorate cardiac conditions by counteracting inflammation. The study aim is t...

journal_title：Journal of endocrinological investigation

authors： Giannattasio S,Corinaldesi C,Colletti M,Di Luigi L,Antinozzi C,Filardi T,Scolletta S,Basili S,Lenzi A,Morano S,Crescioli C

更新日期：2019-06-01 00:00:00

abstract：:Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare, but well-defined monogenic disorder that is caused by mutations in the autoimmune regulator (AIRE) gene on chromosome 21q22.3. Patients most often suffer from loss of endocrine function in the parathyroid and adrenal glands but may also...

journal_title：Journal of endocrinological investigation

authors： Meyer G,Badenhoop K

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:Metastases to the thyroid gland are uncommon and they represent 1-3% of all thyroid malignancy. The aim of this study is to analyze the diagnostic problems and the role of surgery in metastatic lesions to the thyroid. METHODS:We retrospectively analyzed all patients who had undergone thyroidectomy at our Cente...

journal_title：Journal of endocrinological investigation

authors： Battistella E,Pomba L,Mattara G,Franzato B,Toniato A

更新日期：2020-11-01 00:00:00

abstract：:The present experiments were undertaken to study the effect of complete food removal on body weight, pituitary growth hormone (GH), plasma GH and glucose concentration in male and female Wistar rats. Plasma and pituitary GH levels were measured by means of a specific radioimmunoassay. Plasma glucose concentration decr...

journal_title：Journal of endocrinological investigation

authors： Gonzalez C,Jolin T

更新日期：1981-01-01 00:00:00

abstract：:Human thyroid blood flow rate (TBF) was measured during operations by electromagnetic flowmetry in 75 euthyroid patients with normal thyroid tissue, nodular goiter, or solitary adenoma, and in 22 hyperthyroid patients with diffuse or nodular goiter. Blood flow rate was measured in one to four of the thyroid arteries. ...

journal_title：Journal of endocrinological investigation

authors： Tegler L,Gillquist J,Anderberg B,Lundström B,Johansson H

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:Proliferative activity prediction is important for determining individual treatment strategies for patients with acromegaly, and tumor proliferative activity is usually measured by the expression of Ki-67. OBJECTIVE:This study aimed to assess the value of a magnetic resonance imaging (MRI)-based radiomics a...

journal_title：Journal of endocrinological investigation

authors： Fan Y,Chai Y,Li K,Fang H,Mou A,Feng S,Feng M,Wang R

更新日期：2020-06-01 00:00:00

abstract：:Carbenoxolone is a derivative of glycyrrhetinic acid used for the treatment of peptic ulcer and gastritis, with salt and water retention a very common side-effect. To investigate this drug-induced pseudohyperaldosteronism we have studied 6 male volunteers before, during and after treatment with carbenoxolone for 7 day...

journal_title：Journal of endocrinological investigation

authors： Armanini D,Scali M,Zennaro MC,Karbowiak I,Wallace C,Lewicka S,Vecsei P,Mantero F

更新日期：1989-05-01 00:00:00

abstract：:GH secretion in acromegaly was studied in 8 patients before and during treatment with SMS 201-995, a somatostatin analogue, 100 micrograms twice daily, by evaluating GH day profiles and GH suppressibility after oral glucose tolerance tests (OGTT). Normalization of GH secretion, estimated by OGTT, was only observed in ...

journal_title：Journal of endocrinological investigation

authors： van Liessum PA,Pieters GF,Smals AG,Swinkels LM,Benraad TJ,Kloppenborg PW

更新日期：1989-09-01 00:00:00

abstract：:The pathogenesis of human obesity is the result of dysregulation of the reciprocal relationship between food intake and energy expenditure (EE), which influences daily energy balance and ultimately leads to weight gain. According to principles of energy homeostasis, a relatively lower EE in a setting of energy balance...

journal_title：Journal of endocrinological investigation

authors： Piaggi P,Vinales KL,Basolo A,Santini F,Krakoff J

更新日期：2018-01-01 00:00:00