Informing participants of allocation to placebo at trial closure: postal survey.

abstract：OBJECTIVE:To evaluate the cost utility of interferon beta-1b in secondary progressive multiple sclerosis. DESIGN:Population based cost utility model (healthcare perspective). Data on use of health services were obtained from case records and routine morbidity data and utility values from a EuroQol survey. Local and pu...

journal_title：BMJ (Clinical research ed.)

authors： Forbes RB,Lees A,Waugh N,Swingler RJ

更新日期：1999-12-11 00:00:00

abstract：:A randomised controlled trial of two management regimens was carried out in women patients over 65 years of age with hip fractures. Ninety seven patients were admitted to a designated orthopaedic geriatric unit and 125 to orthopaedic wards. No difference was observed in mortality, length of stay, or placement of patie...

journal_title：BMJ (Clinical research ed.)

authors： Gilchrist WJ,Newman RJ,Hamblen DL,Williams BO

更新日期：1988-10-29 00:00:00

abstract：OBJECTIVE:To study the association between wheezy symptoms in young children and the presence of bacteria in the airways. DESIGN:Birth cohort study. SETTING:Clinical research unit in Copenhagen. PARTICIPANTS:Children of asthmatic mothers, from age 4 weeks to 3 years, with planned visits and acute admissions to the r...

journal_title：BMJ (Clinical research ed.)

authors： Bisgaard H,Hermansen MN,Bønnelykke K,Stokholm J,Baty F,Skytt NL,Aniscenko J,Kebadze T,Johnston SL

更新日期：2010-10-04 00:00:00

abstract：OBJECTIVE:To compare incidences of perinatal mortality and severe perinatal morbidity between low risk term pregnancies supervised in primary care by a midwife and high risk pregnancies supervised in secondary care by an obstetrician. DESIGN:Prospective cohort study using aggregated data from a national perinatal regi...

journal_title：BMJ (Clinical research ed.)

authors： Evers AC,Brouwers HA,Hukkelhoven CW,Nikkels PG,Boon J,van Egmond-Linden A,Hillegersberg J,Snuif YS,Sterken-Hooisma S,Bruinse HW,Kwee A

更新日期：2010-11-02 00:00:00

abstract：OBJECTIVES:To examine the concerns of singlehanded general practitioners working in an inner London area and to compare the views of general practitioners in partnerships. DESIGN:Qualitative analysis of semistructured interviews with a random sample of singlehanded general practitioners and a sample of general practit...

journal_title：BMJ (Clinical research ed.)

authors： Green JM

更新日期：1993-09-04 00:00:00

abstract：OBJECTIVES:To investigate the perspectives of patients with asthma on the use of an action plan and the implementation of this plan during an asthma attack that culminated in a visit to an emergency department. DESIGN:Qualitative study. SETTING:Tertiary teaching hospital, suburban hospital, and rural hospital. PARTI...

journal_title：BMJ (Clinical research ed.)

authors： Douglass J,Aroni R,Goeman D,Stewart K,Sawyer S,Thien F,Abramson M

更新日期：2002-04-27 00:00:00

abstract：OBJECTIVES:To determine whether the dose of vitamin A currently recommended by the World Health Organization or half this dose gives better protection against childhood morbidity and mortality. DESIGN:Randomised study. SETTING:A combined oral polio vaccine and vitamin A supplementation campaign in Guinea-Bissau, Afri...

journal_title：BMJ (Clinical research ed.)

authors： Benn CS,Martins C,Rodrigues A,Jensen H,Lisse IM,Aaby P

更新日期：2005-12-17 00:00:00

abstract：OBJECTIVE:To design and evaluate a computer advisory system for the treatment of gestational trophoblastic tumour. DESIGN:A comparison of clinicians' treatment decisions with those of the computer system. Two datasets were used: one to calibrate the system and one to independently evaluate it. SETTING:Department of m...

journal_title：BMJ (Clinical research ed.)

authors： Leaning MS,Gallivan S,Newlands ES,Dent J,Brampton M,Smith DB,Bagshawe KD

更新日期：1992-10-03 00:00:00

abstract：:Some existing laws and some proposed legislation regulating the practice of in vitro fertilization (IVF) limit its availability to infertile couples. Dawson and Singer question whether it is reasonable to so restrict access to IVF, and examine some of the medical and social circumstances in which IVF and the related ...

journal_title：BMJ (Clinical research ed.)

authors： Dawson K,Singer P

更新日期：1990-01-20 00:00:00

abstract：UNLABELLED:OBJECTIVE--To measure needs for care of patients aged 18-65 years with major mental illness. DESIGN:Identification of everyone in one area seen by a health professional within the previous five years because of a psychotic disorder. Interview of a one in three sample of patients and their main carers with t...

journal_title：BMJ (Clinical research ed.)

authors： Murray V,Walker HW,Mitchell C,Pelosi AJ

更新日期：1996-06-22 00:00:00

abstract：OBJECTIVES:To assess the incidence, time of day, and driver morbidity associated with vehicle accidents where the most likely cause was the driver falling asleep at the wheel. DESIGN:Two surveys were undertaken, in southwest England and the midlands, by using police databases or on the spot interviews. SUBJECTS:Drive...

journal_title：BMJ (Clinical research ed.)

authors： Horne JA,Reyner LA

更新日期：1995-03-04 00:00:00

abstract：OBJECTIVE:To evaluate the relative efficacy of programmed cell death 1 (PD-1) or programmed cell death ligand 1 (PD-L1) inhibitors versus conventional drugs in patients with cancer that were PD-L1 positive and PD-L1 negative. DESIGN:Meta-analysis of randomised controlled trials. DATA SOURCES:PubMed, Embase, Cochrane ...

journal_title：BMJ (Clinical research ed.)

authors： Shen X,Zhao B

更新日期：2018-09-10 00:00:00

abstract：OBJECTIVES:Analysis of incidence and characteristics of congenital abdominal wall defects, with special reference to the differences between the incidence of gastroschisis and exomphalos (omphalocele). DESIGN:Retrospective analysis using data from the Office of Population Censuses and Surveys (recoded to differentiate...

journal_title：BMJ (Clinical research ed.)

authors： Tan KH,Kilby MD,Whittle MJ,Beattie BR,Booth IW,Botting BJ

更新日期：1996-10-12 00:00:00

abstract：OBJECTIVES:To compare the efficacy and tolerability of butterbur (Petasites hybridus) with cetirizine in patients with seasonal allergic rhinitis (hay fever). DESIGN:Randomised, double blind, parallel group comparison. SETTING:Four outpatient general medicine and allergy clinics in Switzerland and Germany. PARTICIPA...

journal_title：BMJ (Clinical research ed.)

authors： Schapowal A,Petasites Study Group.

更新日期：2002-01-19 00:00:00

abstract：OBJECTIVE:To identify modifiable factors that influence relatives' decision to allow organ donation. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, and CINAHL, without language restriction, searched to April 2008. Review methods Three authors independently assessed the eligibility of the identified studies. ...

journal_title：BMJ (Clinical research ed.)

authors： Simpkin AL,Robertson LC,Barber VS,Young JD

更新日期：2009-04-21 00:00:00

abstract：OBJECTIVE:To examine whether, according to the conclusions of a 2000 systematic review with meta-analysis on interventions to prevent pain from propofol injection that provided a research agenda to guide further research on the topic, subsequently published trials were more often optimally blinded, reported on children...

journal_title：BMJ (Clinical research ed.)

authors： Habre C,Tramèr MR,Pöpping DM,Elia N

更新日期：2014-08-26 00:00:00

abstract：OBJECTIVE:To study the association between number of cups of coffee consumed per day and coronary death when taking other major coronary risk factors into account. DESIGN:Men and women attending screening and followed up for a mean of 6.4 years. SETTING:Cardiovascular survey performed by ambulatory teams from the Nat...

journal_title：BMJ (Clinical research ed.)

authors： Tverdal A,Stensvold I,Solvoll K,Foss OP,Lund-Larsen P,Bjartveit K

更新日期：1990-03-03 00:00:00

abstract：OBJECTIVE:To map and assess prognostic models for outcome prediction in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Systematic review. DATA SOURCES:PubMed until November 2018 and hand searched references from eligible articles. ELIGIBILITY CRITERIA FOR STUDY SELECTION:Studies developing, valid...

journal_title：BMJ (Clinical research ed.)

authors： Bellou V,Belbasis L,Konstantinidis AK,Tzoulaki I,Evangelou E

更新日期：2019-10-04 00:00:00

abstract：OBJECTIVE:To compare patient outcomes of restrictive versus liberal blood transfusion strategies in patients with cardiovascular disease not undergoing cardiac surgery. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Randomised controlled trials involving a threshold for red blood cell transfusion in hospita...

journal_title：BMJ (Clinical research ed.)

authors： Docherty AB,O'Donnell R,Brunskill S,Trivella M,Doree C,Holst L,Parker M,Gregersen M,Pinheiro de Almeida J,Walsh TS,Stanworth SJ

更新日期：2016-03-29 00:00:00

abstract：OBJECTIVE:To determine whether a booklet given to patients being discharged from hospital giving details of their admission and treatment increased their knowledge and recall when reviewed in outpatient clinics. DESIGN:Patients alternately allocated to receive a booklet or to serve as controls. Assessment by a questio...

journal_title：BMJ (Clinical research ed.)

authors： Sandler DA,Mitchell JR,Fellows A,Garner ST

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE: To directly compare the performance and externally validate the three most studied prediction tools for osteoporotic fractures-QFracture, FRAX, and Garvan-using data from electronic health records. DESIGN: Retrospective cohort study. SETTING: Payer provider healthcare organisation in Israel. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Dagan N,Cohen-Stavi C,Leventer-Roberts M,Balicer RD

更新日期：2017-01-19 00:00:00

abstract：OBJECTIVES:To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the women's understanding of the reasons for their attendance at the hospital clinics...

journal_title：BMJ (Clinical research ed.)

authors： Warner P,Critchley HO,Lumsden MA,Campbell-Brown M,Douglas A,Murray G

更新日期：2001-07-07 00:00:00

abstract：OBJECTIVE:To assess whether using intensive blood pressure targets leads to lower blood pressure in a community population of people with prevalent cerebrovascular disease. DESIGN:Open label randomised controlled trial. SETTING:99 general practices in England, with participants recruited in 2009-11. PARTICIPANTS:Peo...

journal_title：BMJ (Clinical research ed.)

authors： Mant J,McManus RJ,Roalfe A,Fletcher K,Taylor CJ,Martin U,Virdee S,Greenfield S,Hobbs FD

更新日期：2016-02-24 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of interventions designed to improve outcomes in patients with multimorbidity in primary care and community settings. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, CINAHL, CAB Health, Cochrane central register of controlled trials, the database of abstracts of review...

journal_title：BMJ (Clinical research ed.)

authors： Smith SM,Soubhi H,Fortin M,Hudon C,O'Dowd T

更新日期：2012-09-03 00:00:00

abstract：OBJECTIVES:To study the effects of metformin on the incidence of vitamin B-12 deficiency (<150 pmol/l), low concentrations of vitamin B-12 (150-220 pmol/l), and folate and homocysteine concentrations in patients with type 2 diabetes receiving treatment with insulin. DESIGN:Multicentre randomised placebo controlled tri...

journal_title：BMJ (Clinical research ed.)

authors： de Jager J,Kooy A,Lehert P,Wulffelé MG,van der Kolk J,Bets D,Verburg J,Donker AJ,Stehouwer CD

更新日期：2010-05-20 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of parenteral corticosteroids for the relief of acute severe migraine headache and prevention of recurrent headaches. DESIGN:Meta-analysis. DATA SOURCES:Electronic databases (Cochrane Central Register of Controlled Trials, Medline, Embase, LILACS, and CINAHL), conference proceed...

journal_title：BMJ (Clinical research ed.)

authors： Colman I,Friedman BW,Brown MD,Innes GD,Grafstein E,Roberts TE,Rowe BH

更新日期：2008-06-14 00:00:00

abstract：:A brief note on the status of the AIDS pandemic, from the Amsterdam VIIIth International Conference on AIDS, warns that the course of the epidemic is not being altered by prevention efforts. AIDS occurs in every country, usually spread by heterosexual contact, so that women are equally affected with men. WHO estimat...

journal_title：BMJ (Clinical research ed.)

authors： Tanne JH

更新日期：1992-07-25 00:00:00

abstract：OBJECTIVES:To explore general practitioners' reasons for recent changes in their prescribing behaviour. DESIGN:Qualitative analysis of semistructured interviews. SETTING:General practice in south east London. SUBJECTS:A heterogeneous sample of 18 general practitioners. RESULTS:Interviewees were able to identify bet...

journal_title：BMJ (Clinical research ed.)

authors： Armstrong D,Reyburn H,Jones R

更新日期：1996-04-13 00:00:00

abstract：:A total of 563 white primigravid patients at Raigmore Hospital, Inverness, were recruited in a prospective study to examine the association between maternal height, shoe size, and the outcome of labour. There was a significantly increased caesarean section rate in women of short stature but no association between mode...

journal_title：BMJ (Clinical research ed.)

authors： Mahmood TA,Campbell DM,Wilson AW

更新日期：1988-08-20 00:00:00

abstract：OBJECTIVE:To determine whether cognitive therapy is effective in preventing the worsening of emerging psychotic symptoms experienced by help seeking young people deemed to be at risk for serious conditions such as schizophrenia. DESIGN:Multisite single blind randomised controlled trial. SETTING:Diverse services at fi...

journal_title：BMJ (Clinical research ed.)

authors： Morrison AP,French P,Stewart SL,Birchwood M,Fowler D,Gumley AI,Jones PB,Bentall RP,Lewis SW,Murray GK,Patterson P,Brunet K,Conroy J,Parker S,Reilly T,Byrne R,Davies LM,Dunn G

更新日期：2012-04-05 00:00:00