Water extract of Cnidii Rhizoma suppresses RANKL-induced osteoclastogenesis in RAW 264.7 cell by inhibiting NFATc1/c-Fos signaling and prevents ovariectomized bone loss in SD-rat.

abstract：BACKGROUND:The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. METHODS:Leaf and stem extracts of R. punjabensis prepared in 11 d...

journal_title：BMC complementary and alternative medicine

authors： Tabassum S,Ahmed M,Mirza B,Naeem M,Zia M,Shanwari ZK,Khan GM

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:Liver steatosis was caused by lipid accumulation in the liver. Alisma orientale (AO) is recognized as a promising candidate with therapeutic efficacy for the treatment of nonalcoholic fatty liver disease (NAFLD). HepG2 hepatocyte cell line is commonly used for liver disease cell model. METHOD:The HepG2 cell...

journal_title：BMC complementary and alternative medicine

authors： Jeong HS,Cho YH,Kim KH,Kim Y,Kim KS,Na YC,Park J,Lee IS,Lee JH,Jang HJ

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders. Novel whitening and anti-wrinkle compounds from natural products have recently become of increasing interest. The purpose of this study was to find product...

journal_title：BMC complementary and alternative medicine

authors： Chatatikun M,Chiabchalard A

更新日期：2017-11-09 00:00:00

abstract：BACKGROUND:Several studies have indicated that dietary fiber may have a protective effect on gastrointestinal mucosa. The aim of this study was to evaluate the protective action of the soluble fiber Plantago ovata husk against intestinal damage. METHODS:To evaluate the anti-ulcerogenic effect on duodenal mucosa of the...

journal_title：BMC complementary and alternative medicine

authors： Sahagún AM,Vaquera J,García JJ,Calle ÁP,Diez MJ,Fernández N,Loro JF,Portilla HO,Sierra M

更新日期：2015-08-29 00:00:00

abstract：BACKGROUND:Increased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), the main components extracted from Panax notoginseng, has been shown to be efficacious in the prevention and treatment of ischemic stroke in...

journal_title：BMC complementary and alternative medicine

authors： Qi H,Huang Y,Yang Y,Dou G,Wan F,Zhang W,Yang H,Wang L,Wu C,Li L

更新日期：2016-06-08 00:00:00

abstract：BACKGROUND:Moxibustion (a type of Chinese medicine which involves burning a herb close to the skin) has been used to correct a breech presentation. Evidence of effectiveness and safety from systematic reviews is encouraging although significant heterogeneity has been found among trials. We assessed the feasibility of c...

journal_title：BMC complementary and alternative medicine

authors： Do CK,Smith CA,Dahlen H,Bisits A,Schmied V

更新日期：2011-09-26 00:00:00

abstract：BACKGROUND:Dermal wound healing involves a cascade of complex events including angiogenesis and extracellular matrix remodeling. Several groups have focused in the study of the skin wound healing activity of natural products. The phytomedicine Acheflan®, and its main active constituent is the oil from Cordia verbenacea...

journal_title：BMC complementary and alternative medicine

authors： Perini JA,Angeli-Gamba T,Alessandra-Perini J,Ferreira LC,Nasciutti LE,Machado DE

更新日期：2015-06-30 00:00:00

abstract：BACKGROUND:The purpose of this study was to compare the efficacy of electroacupuncture (EA), diclofenac and their combination in symptomatic treatment of osteoarthritis (OA) of the knee. METHODS:This study was a randomized, single-blind, placebo controlled trial. The 193 out-patients with OA of the knee were randomize...

journal_title：BMC complementary and alternative medicine

authors： Sangdee C,Teekachunhatean S,Sananpanich K,Sugandhavesa N,Chiewchantanakit S,Pojchamarnwiputh S,Jayasvasti S

更新日期：2002-03-21 00:00:00

abstract：BACKGROUND:Previous publications indicate that acupuncture is efficient for the treatment of pelvic girdle pain, PGP, in pregnant women. However, the use of acupuncture for PGP is rare due to insufficient documentation of adverse effects of this treatment in this specific condition. The aim of the present work was to a...

journal_title：BMC complementary and alternative medicine

authors： Elden H,Ostgaard HC,Fagevik-Olsen M,Ladfors L,Hagberg H

更新日期：2008-06-26 00:00:00

abstract：BACKGROUND:The leaves of Leea indica (Vitaceae), commonly known as 'Huo Tong Shu' in Malaysia, have been traditionally used as natural remedy in folk medicine by the locals. The current study reports the outcome of antioxidant and cytotoxic investigation of L. indica leaves. To the best of our knowledge, this is the fi...

journal_title：BMC complementary and alternative medicine

authors： Reddy NS,Navanesan S,Sinniah SK,Wahab NA,Sim KS

更新日期：2012-08-17 00:00:00

abstract：BACKGROUND:Exposure to carbon black nanoparticles (CBNPs), a well-known industrial production, promotes pulmonary toxicity through inflammation and oxidative stress. Recent studies show that some polyphenols exert their antioxidant properties through regulation of protein kinase C-α (PKC-α) and NADPH oxidase (Nox) sign...

journal_title：BMC complementary and alternative medicine

authors： Hsu HT,Tseng YT,Wong WJ,Liu CM,Lo YC

更新日期：2018-07-09 00:00:00

abstract：BACKGROUND:Ginkgo biloba extract (GbE) is used extensively by breast cancer patients undergoing treatment with Tamoxifen (TAM). Thus, the present study investigated the effects of GbE in female Sprague-Dawley (SD) rats bearing chemically-induced mammary tumors and receiving TAM. METHODS:Animals bearing mammary tumors ...

journal_title：BMC complementary and alternative medicine

authors： Dias MC,Furtado KS,Rodrigues MA,Barbisan LF

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Plant medicinal extracts may be claimed to prevent or cure chemical intoxications. Few of these are tested for their mechanisms of actions in vivo and for their cellular impacts. In 2011, we demonstrated that hepatic cell mortality induced by environmentally realistic levels of the widely used herbicide Roun...

journal_title：BMC complementary and alternative medicine

authors： Gress S,Laurant C,Defarge N,Travert C,Séralini GÉ

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:Whole-body electrical myostimulation (WB-EMS) is a relatively recent training methodology that has been extraordinarily used in recent years. However, there is a lack of consensus on the effectiveness of WB-EMS in the situations in which its use has been largely popularized. The objective of this systematic ...

journal_title：BMC complementary and alternative medicine

authors： Pano-Rodriguez A,Beltran-Garrido JV,Hernández-González V,Reverter-Masia J

更新日期：2019-04-24 00:00:00

abstract：BACKGROUND:The use of complementary and alternative medicine (CAM) persists, despite the availability of conventional medicine (CM), modernisation, globalisation, technological advancement, and limited scientific evidence supporting CAM. People with cardiovascular diseases often use CAM, despite possible major adverse ...

journal_title：BMC complementary and alternative medicine

authors： Bahall M

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:In traditional Chinese and Korean medicine, an aqueous extract derived from wood and bark of the Japanese spice bush Lindera obtusiloba (L.obtusiloba) is applied to treat inflammations and chronic liver diseases including hepatocellular carcinoma. We previously demonstrated anti-fibrotic effects of L.obtusil...

journal_title：BMC complementary and alternative medicine

authors： Freise C,Ruehl M,Erben U,Neumann U,Seehofer D,Kim KY,Trowitzsch-Kienast W,Stroh T,Zeitz M,Somasundaram R

更新日期：2011-05-12 00:00:00

abstract：BACKGROUND:Consumption of plant-derived nutraceuticals and crude drugs in traditional medicine is widely believed to confer beneficial effects in thwarting the progression of cardiovascular diseases. Rhus tripartita (family Anacardiaceae) has been traditionally used to treat a wide range of ailments. METHODS:In the pr...

journal_title：BMC complementary and alternative medicine

authors： Shahat AA,Alsaid MS,Rafatullah S,Al-Sohaibani MO,Parvez MK,Al-Dosari MS,Exarchou V,Pieters L

更新日期：2016-09-08 00:00:00

abstract：BACKGROUND:Danqi pill (DQP) is one of the most widely prescribed formulas and has been shown to have remarkable protective effect on coronary heart disease (CHD). However, its regulatory effects on lipid metabolism disorders haven't been comprehensively studied so far. We aimed to explore the effects of DQP on Peroxiso...

journal_title：BMC complementary and alternative medicine

authors： Chang H,Wang Q,Shi T,Huo K,Li C,Zhang Q,Wang G,Wang Y,Tang B,Wang W,Wang Y

更新日期：2016-03-22 00:00:00

abstract：BACKGROUND:Use of complementary medicine is common, consumer driven and usually outpatient focused. We wished to determine interest among the medical staff at a North Carolina academic medical center in integrating diverse therapies and services into comprehensive care. METHODS:We conducted a cross sectional on-line s...

journal_title：BMC complementary and alternative medicine

authors： Kemper KJ,Dirkse D,Eadie D,Pennington M

更新日期：2007-02-09 00:00:00

abstract：BACKGROUND:This systematic review aimed at summarizing and evaluating the evidence of randomized controlled trials (RCTs) using acupuncture to improve endometrial receptivity (ER). METHODS:We searched 12 databases electronically through August 2018 without language restrictions. We included RCTs of women of infertilit...

journal_title：BMC complementary and alternative medicine

authors： Zhong Y,Zeng F,Liu W,Ma J,Guan Y,Song Y

更新日期：2019-03-13 00:00:00

abstract：BACKGROUND:Musk is widely used in clinical practice for its anti-cancer properties. Here, we treated various types of cancer using musk to determine which cancers are sensitive to musk treatment. We also compared effects of native musk and synthetic musk ketone in cancer cells. Furthermore, we investigated mechanisms u...

journal_title：BMC complementary and alternative medicine

authors： Xu L,Cao Y

更新日期：2016-12-08 00:00:00

abstract：BACKGROUND:Mitochondrial dysfunction has been implicated in neuronal apoptosis associated with neurodegenerative diseases such as Huntington's disease (HD). Animals that are administered 3-nitropropionic acid (3-NP), a mitochondrial toxin that specifically inhibits complex II of the mitochondrial electron transport cha...

journal_title：BMC complementary and alternative medicine

authors： Im AR,Chae SW,Zhang GJ,Lee MY

更新日期：2014-10-03 00:00:00

abstract：BACKGROUND:The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barteri is popularly used in the West region of Cameroon for the treatment of various diseases such as ...

journal_title：BMC complementary and alternative medicine

authors： Atsafack SS,Kuiate JR,Mouokeu RS,Koanga Mogtomo ML,Tchinda AT,De Dieu TJ,Magnifouet Nana H,Ebelle Etame RM,Biyiti L,Ngono Ngane RA

更新日期：2015-03-07 00:00:00

abstract：BACKGROUND:Fibrosis is a major contributor to systemic sclerosis (SSc)-related morbidity, and rapid, progressive skin involvement predicts later mortality. Western medicine therapies for SSc cannot produce satisfactory effects currently, while Traditional Chinese Medicine (TCM), such as the Wenyang Huazhuo Tongluo (WYH...

journal_title：BMC complementary and alternative medicine

authors： Han L,Bian H,Ouyang J,Bi Y,Yang L,Ye S

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Since ancient times, honey has been used for medicinal purposes in many cultures; it is one of the oldest and most enduring substances used in wound management. Scientific evidence for its efficacy is widely studied, but systemic safety studies are still lacking. It is essential to study the impact of consum...

journal_title：BMC complementary and alternative medicine

authors： Samat S,Nor NA,Nor Hussein F,Ismail WI

更新日期：2014-05-04 00:00:00

abstract：BACKGROUND:Liriope platyphylla has long been reported as a therapeutic drug for treatment of various human chronic diseases including inflammation, diabetes, neurodegenerative disorders, obesity, and atopic dermatitis. To investigate the laxative effects of L. platyphylla, alterations in excretion parameters, histologi...

journal_title：BMC complementary and alternative medicine

authors： Kim JE,Lee YJ,Kwak MH,Ko J,Hong JT,Hwang DY

更新日期：2013-11-26 00:00:00

abstract：BACKGROUND:Clinacanthus nutans extracts have been consumed by the cancer patients with the hope that the extracts can kill cancers more effectively than conventional chemotherapies. Our previous study reported its anti-inflammatory effects were caused by inhibiting Toll-like Receptor-4 (TLR-4) activation. However, we a...

journal_title：BMC complementary and alternative medicine

authors： Hii LW,Lim SE,Leong CO,Chin SY,Tan NP,Lai KS,Mai CW

更新日期：2019-09-14 00:00:00

abstract：BACKGROUND:Human skin properties have been used as an important diagnostic component in traditional medicine as they change with health conditions. Sasang constitutional medicine (SCM) puts emphasis on the recognition of the constitution-specific skin features prior to the diagnostic decision of health. In this work, i...

journal_title：BMC complementary and alternative medicine

authors： Kim YM,Ku B,Jung CJ,Kim JU,Jeon YJ,Kim KH,Kim JY

更新日期：2014-01-15 00:00:00

abstract：BACKGROUND:Liver disease is the major cause of serious health problem leading to morbidity and mortality worldwide and the problem has increased in search for hepatotherapeutic agents from plants. The present study was designed to compare the probable hepatoprotective activity of olive oil and N. sativa oil on CCl4 ind...

journal_title：BMC complementary and alternative medicine

authors： Al-Seeni MN,El Rabey HA,Zamzami MA,Alnefayee AM

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:Several compounds isolated from Dryobalanops have been reported to exhibit cytotoxic effects to several cancer cell lines. This study investigated the cytotoxic effects, cell cycle arrest and mode of cell death in ampelopsin E-treated triple negative cells, MDA-MB-231. METHODS:Cytotoxicity of ampelopsin E, ...

journal_title：BMC complementary and alternative medicine

authors： Rahman NA,Yazan LS,Wibowo A,Ahmat N,Foo JB,Tor YS,Yeap SK,Razali ZA,Ong YS,Fakurazi S

更新日期：2016-09-08 00:00:00