Abstract:
BACKGROUND:The assessment of residual gastric volume is common practice in critical care units. However, the effects and safety of discarding or returning gastric aspirates remain uncertain. Therefore, we aimed to evaluate the role of discarding or returning gastric aspirates on the gastric residual volumes in critically ill patients. METHODS:A comprehensive, systematic meta-analysis of randomized controlled trials (RCTs) on the efficacy and safety of discarding or returning gastric aspirates in critical ill patients was performed. Studies were identified by searching Pubmed and other databases (from inception to 31 Sept 2018). Summary odd ratios (ORs) or mean differences (MDs) with 95% confidence intervals were calculated using fixed- or random-effects model for outcome assessment. RESULTS:Four RCTs, with a total number of 314 adult patients, were included in the analysis. No significant differences were found in the 48th hour residual volume (MD = 8.89, 95% CI: 11.97 to 29.74), the average potassium level (MD = 0.00, 95% CI: - 0.16 to 0.16), the episodes of gastric emptying delay (OR = 0.98, 95% CI: 0.35 to 2.80), the incidence of aspiration pneumonia (OR = 0.93, 95% CI: 0.14 to 6.17), the episodes of nausea or vomiting (OR = 0.53, 95% CI: 0.07 to 4.13) and diarrhea (OR = 0.99, 95% CI: 0.58 to 1.70). CONCLUSIONS:No evidence confirms that returning residual gastric aspirates provides more benefits than discarding them without increasing potential complications. Rigorously designed, multi-center, large-sample randomized controlled trials must be further conducted to validate the role of discarding or returning residual gastric aspirates.
journal_name
BMC Gastroenteroljournal_title
BMC gastroenterologyauthors
Wen Z,Xie A,Peng M,Bian L,Wei L,Li Mdoi
10.1186/s12876-019-1028-7subject
Has Abstractpub_date
2019-06-28 00:00:00pages
113issue
1issn
1471-230Xpii
10.1186/s12876-019-1028-7journal_volume
19pub_type
杂志文章,meta分析abstract:BACKGROUND:Hereditary diffuse gastric cancer is a rare condition that accounts for approximately 1-3% of all gastric cancer cases. Due to its rapid and invasive growth pattern, it is associated with a very poor prognosis. As a result, comprehensive genetic testing is imperative in patients who meet the current testing ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
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abstract:BACKGROUND:Patients often experience severe weight loss after oesophagectomy. Enteral nutrition via a feeding jejunostomy tube (FT) is commonly practised. This study aimed to assess the effect of severe weight loss postoperatively and enteral nutrition via an FT on long-term prognosis after oesophagectomy. METHODS:Thi...
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abstract:BACKGROUND:Infliximab is usually administered by two monthly intravenous (iv) infusions, therefore requiring visits to hospital. Adalimumab is administered by self subcutaneous (sc) injections every other week. Both of these anti-TNF drugs appear to be equally efficacious in the treatment of Crohn's Disease and therefo...
journal_title:BMC gastroenterology
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abstract:BACKGROUND:Vitamin K deficiency results in serious coagulation dysfunction, but hemorrhagic shock is rare. Herein, we describe a case of vitamin K deficiency and abnormality in the path of the intercostal artery, the combination of which led to hemorrhagic shock. CASE PRESENTATION:An 83-year-old woman was hospitalized...
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pub_type: 杂志文章
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abstract:BACKGROUND:Microscopic colitis presents with similar symptoms to classic inflammatory bowel diseases. Osteoporosis is a common complication of Crohn's disease but there are no data concerning bone metabolism in microscopic colitis. AIMS:The aim of the present study was to evaluate bone density and metabolism in patien...
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pub_type: 杂志文章
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更新日期:2011-05-19 00:00:00
abstract:BACKGROUND:Low 25-Hydroxy-vitamin-D; "25(OH)-D3" serum and vitamin D receptor (VDR) levels were recently correlated to advanced fibrosis. However, VDR mechanism in liver fibrosis modulations is not well understood. In this study, we aimed to evaluate changes in liver NK cells cytotoxicity due to modulations in VDR in C...
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abstract:BACKGROUND:Mini-Mental State Examination (MMSE) is one of the most commonly used methods in the assessment of cognitive mental status. MMSE has been used in hepatology but its usefulness in the evaluation of hepatic encephalopathy (HE) has never been properly assessed. The aim of the study was to investigate the value ...
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pub_type: 临床试验,杂志文章
doi:10.1186/1471-230X-13-107
更新日期:2013-07-02 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-3-12
更新日期:2003-06-06 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2012-11-16 00:00:00
abstract:BACKGROUNDS:Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in Asians. However, data on prevalence and factors associated with NAFLD in Asians are lacking. The aim of this study is to investigate the prevalence of NAFLD in Shanghai employees to assess the relationship between N...
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pub_type: 杂志文章
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abstract:BACKGROUND:Pancreatic cancer has significant morbidity and mortality worldwide. Good prognosis relies on an early diagnosis. The purpose of this study was to develop techniques for identifying cancer biomarkers in the serum of patients with pancreatic cancer. METHODS:Serum samples from five individuals with pancreatic...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-10-68
更新日期:2010-06-29 00:00:00
abstract:BACKGROUND:By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflux disease (NERD) and those with reflux hypersensitivity (RH). Therefore, in this study, we investiga...
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pub_type: 杂志文章
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更新日期:2017-05-23 00:00:00
abstract:BACKGROUND:Although the outcomes of caustic ingestion differ between children and adults, it is unclear whether such outcomes differ among adults as a function of their age. This retrospective study was performed to ascertain whether the clinical outcomes of caustic ingestion differ significantly between elderly and no...
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pub_type: 杂志文章
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更新日期:2011-06-14 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) infection is commonly associated with a disturbance of glucose metabolism. However, there have been conflicting reports on whether the clearance of the HCV may be followed by changes of serum blood glucose and insulin resistance. The aim of the present study was to evaluate the impact...
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pub_type: 杂志文章
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更新日期:2019-06-13 00:00:00
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pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12876-018-0849-0
更新日期:2018-09-04 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2016-07-26 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-230X-5-4
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2007-06-08 00:00:00
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pub_type: 杂志文章
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更新日期:2020-06-10 00:00:00
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pub_type: 杂志文章
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更新日期:2015-10-14 00:00:00
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pub_type: 杂志文章,多中心研究
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journal_title:BMC gastroenterology
pub_type: 杂志文章
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更新日期:2020-04-19 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2012-07-09 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2010-09-06 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
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更新日期:2012-09-25 00:00:00