Abstract：
BACKGROUND:Guttate psoriasis is a distinctive acute form of psoriasis which characteristically occurs in children and young adults. Very little specific evidence-based guidance is available in standard texts to help make rational decisions about treatment options. OBJECTIVES:To assess the effectiveness of treatments for guttate psoriasis. SEARCH METHODS:We searched the Cochrane Clinical Trials Register (Cochrane Library, Issue 3, 1999), Medline (1966- September 1999), Embase (1988-September 1999), Salford Database of Psoriasis Trials (to November 1999) and European Dermato-Epidemiology Network (EDEN) Psoriasis Trials Database (to November 1999) for terms GUTTATE and PSORIASIS. We also searched 100 unselected RCTs of psoriasis therapy and all 112 RCTs of phototherapy for psoriasis in the Salford Database of Psoriasis Trials for separate stratification for guttate psoriasis. SELECTION CRITERIA:Randomised trials in which patients with acute guttate psoriasis were randomised to different treatments, except those trials examining antistreptococcal interventions which are addressed in a separate Cochrane review. DATA COLLECTION AND ANALYSIS:Two reviewers independently assessed trial eligibility and quality. MAIN RESULTS:No published report could be found to support or to challenge current commonly used methods of management.Only one trial which met the selection criteria was identified. In this small study of 21 hospitalised patients with guttate psoriasis, intravenous infusion of an n-3 fatty acid rich lipid emulsion was compared with placebo emulsion containing n-6 fatty acids. The n-3 preparation appeared to be of some benefit for patients with guttate psoriasis. AUTHORS' CONCLUSIONS:There is currently no firm evidence on which to base treatment of acute guttate psoriasis. Studies comparing standard treatment modalities, including phototherapy and topical regimens, are required to enable informed decisions on treatment choices to be made.
journal_name
Cochrane Database Syst Revjournal_title
The Cochrane database of systematic reviewsauthors
Chalmers R,O'Sullivan T,Owen CM,Griffiths CEdoi
10.1002/14651858.CD001213.pub2subject
Has Abstractpub_date
2019-04-09 00:00:00pages
CD001213issn
1469-493Xjournal_volume
4pub_type
杂志文章,评审abstract：BACKGROUND:Electronic mosquito repellents (EMRs) are marketed to prevent mosquitoes biting and to prevent malaria. OBJECTIVES:To assess whether EMRs prevent mosquito bites, and to assess any evidence of an effect on malaria infection. SEARCH STRATEGY:In August 2006, we searched the Cochrane Infectious Diseases Group ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD005434.pub2
更新日期：2007-04-18 00:00:00
abstract：BACKGROUND:Traumatic experiences evoke emotions such as fear, anxiety and distress and may encourage avoidance of similar situations in the future. For a proportion of those exposed to a traumatic event, this emotional reaction becomes uncontrollable and can develop into Post Traumatic Stress Disorder (PTSD) (Breslau 2...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD007171.pub2
更新日期：2010-01-20 00:00:00
abstract：BACKGROUND:Oxygen has long been implicated in the pathogenesis of retinopathy of prematurity (ROP) and is rigorously monitored in today's neonatal intensive care units. Recent research using a feline model has shown an improvement in ROP outcome of kittens treated with supplemental oxygen. Current treatment for ROP by ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD003482
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:Mental health problems in children are common. Research suggests that parenting has an important role to play in helping children to become well adjusted adults, and that the first few months and years of a child's life are especially important in establishing patterns of emotional, cognitive and social func...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD003680
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Elevated levels of total cholesterol and low-density lipoprotein play an important role in the development of atheromas and, therefore, in cardiovascular diseases. Cholesterol biosynthesis follows a circadian rhythm and is principally produced at night (between 12:00 am and 6:00 am). The adjustment of hypoli...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD009462.pub2
更新日期：2016-11-26 00:00:00
abstract：BACKGROUND:Over the last two decades, a long protocol of Gonadotrophin-releasing hormone agonist (GnRHa) to prevent premature LH surges has been the standard treatment for ovarian stimulation in assisted reproduction. In the long protocols (with GnRHa started either in the mid luteal phase or in the early follicular ph...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001750
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Many hormonal contraceptives have been associated with changes in carbohydrate metabolism. Alterations may include decreased glucose tolerance and increased insulin resistance, which are risk factors for Type 2 diabetes mellitus and cardiovascular disease. These issues have been raised primarily with contrac...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD006133.pub5
更新日期：2014-04-30 00:00:00
abstract：BACKGROUND:Adjuvant tamoxifen reduces the risk of breast cancer recurrence in women with estrogen receptor-positive breast cancer. Tamoxifen also increases the risk of postmenopausal bleeding, endometrial hyperplasia, polyps, and endometrial cancer. The levonorgestrel-releasing intrauterine system (LNG-IUS) causes prof...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD007245.pub2
更新日期：2009-10-07 00:00:00
abstract：OBJECTIVES:To compare the efficacy and safety of adjuvant pramipexole therapy versus inactive placebo in patients with Parkinson's disease, already established on levodopa. SEARCH STRATEGY:Electronic searches of MEDLINE, EMBASE and the Cochrane Controlled Trials Register. Handsearching of the neurology literature as p...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD002261
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) is defined as reduced function of the kidneys present for 3 months or longer with adverse implications for health and survival. For several decades low protein diets have been proposed for participants with CKD with the aim of slowing the progression to end-stage kidney disease (...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD001892.pub5
更新日期：2020-10-29 00:00:00
abstract：BACKGROUND:Heavy menstrual bleeding significantly impairs the quality of life of many otherwise healthy women. Perception of heavy menstrual bleeding is subjective and management usually depends upon what symptoms are acceptable to the individual. Surgical options include conservative surgery (uterine resection or abla...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003855.pub3
更新日期：2016-01-29 00:00:00
abstract：BACKGROUND:Concerns regarding the safety of transfused blood, have prompted reconsideration of the use of allogeneic (blood from an unrelated donor) red blood cell (RBC) transfusion, and a range of techniques to minimise transfusion requirements. OBJECTIVES:To examine the evidence for the efficacy of cell salvage in r...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD001888
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:Percutaneous dilatational tracheostomy (PDT) is one of the most common bedside surgical procedures performed in critically ill adults, on intensive care units (ICUs), who require long-term ventilation. PDT is associated with relevant life-threatening complications: Cuff rupture or accidental extubation may l...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD009901.pub3
更新日期：2018-11-15 00:00:00
abstract：BACKGROUND:There is an ongoing debate about the indications for, and value of, adjuvant pelvic radiotherapy after radical surgery in women with early cervical cancer. Certain combinations of pathologic risk factors are thought to represent sufficient risk for recurrence, that they justify the use of post-operative pelv...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD007583.pub2
更新日期：2009-10-07 00:00:00
abstract：BACKGROUND:Functional immaturity of gastrointestinal motility predisposes preterm infants to feeding intolerance. Motilin, a gastrointestinal peptide, stimulates propagative contractile activity during phase III of the migratory motor complex in the interdigestive state. Erythromycin (EM) is a motilin agonist with prok...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001815
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:A significant number of patients who suffer with anxiety and related disorders (that is post-traumatic stress disorder (PTSD), social anxiety disorder (SAnD), panic disorder with or without agoraphobia (PD), specific phobia (SPh) and obsessive compulsive disorder (OCD)) fail to respond optimally to first-lin...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD007803.pub2
更新日期：2015-05-10 00:00:00
abstract：BACKGROUND:Perineal trauma is common during childbirth and may be painful. Contemporary maternity practice includes offering women numerous forms of pain relief, including the local application of cooling treatments. This Cochrane Review is an update of a review last updated in 2012. OBJECTIVES:To evaluate the effecti...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD006304.pub4
更新日期：2020-10-09 00:00:00
abstract：BACKGROUND:People with depression often experience interpersonal problems. Family therapy for depression is a widely used intervention, but it is unclear whether this is an effective therapy for the treatment of depression. OBJECTIVES:To assess the efficacy of family therapy for depression. SEARCH STRATEGY:The follow...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD006728
更新日期：2007-07-18 00:00:00
abstract：BACKGROUND:Family centred care is an important part of neonatal intensive care. Ensuring effective communication in the neonatal intensive care unit (NICU) is a challenge but is crucial to the implementation of family centred care. Providing parents in NICU with audiotape recordings of their conversations with neonatol...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD004502.pub2
更新日期：2005-01-25 00:00:00
abstract：BACKGROUND:Oral analgesia is a convenient and widely used form of pain relief following caesarean section. It includes various medications used at different doses alone or in adjunction to other form of analgesia. OBJECTIVES:To determine the effectiveness, safety and cost-effectiveness of oral analgesia for post-caesa...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD010450.pub2
更新日期：2015-03-29 00:00:00
abstract：BACKGROUND:Double volume exchange transfusion is commonly used in newborns with severe jaundice in order to prevent kernicterus and other toxicity related to hyperbilirubinemia. Most commonly, exchange transfusions are used in infants with rhesus hemolytic disease. OBJECTIVES:To compare the effectiveness of single vol...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD004592.pub2
更新日期：2006-10-18 00:00:00
abstract：BACKGROUND:Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the dissemination of endometrium to ectopic sites and the subsequent establishment of...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD000346
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Several studies have suggested that prophylactic antibiotics given during pregnancy improved maternal and perinatal outcomes, while others have shown no benefit and some have reported adverse effects. OBJECTIVES:To determine the effect of prophylactic antibiotics on maternal and perinatal outcomes during th...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD002250.pub2
更新日期：2015-01-26 00:00:00
abstract：BACKGROUND:Depressive illness in older people causes significant suffering and health service utilisation. Relapse and recurrence rates are high. OBJECTIVES:To examine the efficacy of antidepressants and psychological therapies in preventing the relapse and recurrence of depression in older people. SEARCH METHODS:Sea...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD006727.pub2
更新日期：2012-11-14 00:00:00
abstract：BACKGROUND:Antipsychotic drugs are the mainstay treatment for schizophrenia. Long-acting depot injections of drugs such as bromperidol decanoate are extensively used as a means of long-term maintenance treatment. OBJECTIVES:To assess the effects of depot bromperidol versus placebo, oral antipsychotics and other depot ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001719.pub2
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:Pain is the most frequent symptom experienced by cancer patients, its intensity dependent on the site of the tumour. Tumours that compromise bone or nervous structures due to the bone destruction process are the most painful. There are several treatments to deal with pain (and other symptoms) caused by bone ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003223.pub2
更新日期：2006-07-19 00:00:00
abstract：BACKGROUND:Inguinal or femoral hernia is a tissue protrusion in the groin region and has a cumulative incidence of 27% in adult men and of 3% in adult women. As most hernias become symptomatic over time, groin hernia repair is one of the most frequently performed surgical procedures worldwide. This type of surgery is c...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD003769.pub5
更新日期：2020-04-21 00:00:00
abstract：BACKGROUND:Actinic keratoses are a skin disease caused by long-term sun exposure, and their lesions have the potential to develop into squamous cell carcinoma. Treatments for actinic keratoses are sought for cosmetic reasons, for the relief of associated symptoms, or for the prevention of skin cancer development. Detec...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD004415.pub2
更新日期：2012-12-12 00:00:00
abstract：BACKGROUND:Sevoflurane induction for general anaesthesia has been reported to be safe, reliable and well accepted by patients. Sevoflurane induction uses either low or high initial concentrations. The low initial concentration technique involves initially administering a low concentration then gradually increasing the ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD006837.pub2
更新日期：2012-09-12 00:00:00
abstract：OBJECTIVES:To assess the short-term effects of azathioprine for the treatment of rheumatoid arthritis (RA). SEARCH STRATEGY:We searched the Cochrane Musculoskeletal Group's trials register, the Cochrane Controlled Trials Register (issue 3, 2000), Medline up to and including August 2000 and Embase from 1988 to August 2...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001461
更新日期：2000-01-01 00:00:00
