Abstract:
BACKGROUND:Epidemiological studies regarding the association between dietary fiber intake and ovarian cancer risk are still inconsistent. We aimed to review the available evidence and conduct a dose-response meta-analysis to investigate the relationship between dietary fiber intake and ovarian cancer risk. METHODS:Relevant studies were identified by searching PubMed, EMBASE, and the Cochrane Library databases before August 2017. Studies that reported relative risk (RR) estimates with 95% confidence intervals (CIs) for the association between dietary fiber intake and risk of ovarian cancer were included. Random-effects models were used to combine the estimated effects extracted from individual study. RESULTS:Thirteen studies, with a total of 5777 ovarian cancer cases and 142,189 participants, met the inclusion criteria. The pooled multivariable RRs of ovarian cancer for the highest vs. the lowest category of dietary fiber intake was 0.78 (95% CI: 0.70, 0.88) with no evidence of heterogeneity (I2 = 4.20%, P = 0.40). Our dose-response analysis also showed a significant inverse association between dietary fiber intake and ovarian cancer risk (an increment of 10 g/day; combined RR: 0.88; 95% CI: 0.82, 0.93). There was no evidence for a nonlinear association (P for nonlinearity = 0.83). CONCLUSIONS:This meta-analysis suggests a significant inverse dose-response association between dietary fiber intake and ovarian cancer risk. Further studies with prospective design that take account of more potential confounders are warranted to confirm this association.
journal_name
Nutr Jjournal_title
Nutrition journalauthors
Zheng B,Shen H,Han H,Han T,Qin Ydoi
10.1186/s12937-018-0407-1subject
Has Abstractpub_date
2018-10-30 00:00:00pages
99issue
1issn
1475-2891pii
10.1186/s12937-018-0407-1journal_volume
17pub_type
杂志文章,meta分析abstract:BACKGROUND:Isoflavones comprise a class of phytoestrogens that resemble human estrogen in chemical structure, and have weak estrogenic effects. Because estrogen modulates sleep duration and quality, we hypothesized that isoflavones would have a beneficial effect on sleep status in a way similar to estrogen. We conducte...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-015-0117-x
更新日期:2015-12-29 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
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abstract:BACKGROUND:Due to the absence of a current and validated food frequency questionnaire (FFQ) for use in New Zealand adolescents, there is a need to develop one as a cost-effective way to assess adolescents' food patterns. This study aims to examine the test-retest reliability and relative validity of the New Zealand Ado...
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
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更新日期:2015-05-06 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-8-19
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journal_title:Nutrition journal
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doi:10.1186/s12937-015-0097-x
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journal_title:Nutrition journal
pub_type: 杂志文章,评审
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更新日期:2010-12-22 00:00:00
abstract:UNLABELLED:Coeliac disease is an important clinical disorder affecting the human gastrointestinal tract leading to multiple signs and symptoms in different body organs. This disease was the subject of a cross sectional descriptive-analytic study conducted in the Gaza Strip during 2010. Objectives were oriented to ident...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-11-97
更新日期:2012-11-20 00:00:00
abstract:BACKGROUND:In order to rapidly assess nutrient intake, Food Frequency Questionnaires (FFQ) have been developed and proven to be reliable for quick, user friendly analysis in adults. However, the accuracy of these questionnaires in children has been studied to a limited extent. The aim of this study was to compare the d...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-6-24
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-5-27
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journal_title:Nutrition journal
pub_type: 临床试验,杂志文章
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更新日期:2013-10-11 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-017-0285-y
更新日期:2017-09-18 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-10-72
更新日期:2011-06-29 00:00:00
abstract::Childhood obesity has reached epidemic levels in developed countries. Twenty five percent of children in the US are overweight and 11% are obese. Overweight and obesity in childhood are known to have significant impact on both physical and psychological health. The mechanism of obesity development is not fully underst...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2891-4-24
更新日期:2005-09-02 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00625-w
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-019-0445-3
更新日期:2019-03-28 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-018-0418-y
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abstract:BACKGROUND:Intra-articular hyaluronic acid represents a substantive addition to the therapeutic armamentarium in knee osteoarthritis. We examined the effect of dietary supplementation with a natural extract of chicken combs with a high content of hyaluronic acid (60%) (Hyal-Joint) (active test product, AP) on pain and ...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-7-3
更新日期:2008-01-21 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-2-19
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journal_title:Nutrition journal
pub_type: 杂志文章
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-77
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-53
更新日期:2011-05-18 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-4-20
更新日期:2005-06-01 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1475-2891-10-123
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-12-29
更新日期:2013-03-05 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12937-016-0169-6
更新日期:2016-05-04 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-11-85
更新日期:2012-10-15 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-12-70
更新日期:2013-06-02 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-015-0022-3
更新日期:2015-04-14 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00596-y
更新日期:2020-08-22 00:00:00