Identification of a distinct phenotype of elderly latent autoimmune diabetes in adults: LADA China Study 8.

abstract：BACKGROUND:The aim of this study was to assess the clinical implications of calculating an individualized HbA1c target using a recently published algorithm in a real-life clinical setting. METHODS:General practitioners (GPs) from the Spanish Society of Family Medicine Diabetes Expert Group were invited to participate ...

journal_title：Diabetes/metabolism research and reviews

authors： Alvarez-Guisasola F,Cebrián-Cuenca AM,Cos X,Ruiz-Quintero M,Millaruelo JM,Cahn A,Raz I,Orozco-Beltrán D,Spanish Society of Family Medicine Diabetes Group.

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Sustained hyperglycaemia induces increased renal oxygen consumption resulting in reduced oxygen availability in the diabetic kidney. We investigated the roles of the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase and the neuronal nitric oxide synthase (nNOS) for the increased oxygen consumption ...

journal_title：Diabetes/metabolism research and reviews

authors： Edlund J,Fasching A,Liss P,Hansell P,Palm F

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The active cognitive-motor demands of driving may have a significant metabolic demand that could contribute to the development of hypoglycemia. Conversely, symptoms caused by the stress of driving may be confused with hypoglycemia and lead to false alarms. This study examined the metabolic demand and the phy...

journal_title：Diabetes/metabolism research and reviews

authors： Cox DJ,Gonder-Frederick LA,Kovatchev BP,Clarke WL

更新日期：2002-09-01 00:00:00

abstract：:Fulminant type 1 diabetes (fT1D) is a new subtype of type 1 diabetes proposed by Imagawa in 2000. It is a clinical syndrome characterized by a markedly rapid and almost complete destruction of pancreatic β cells. Metabolic derangement is more severe in this subtype than in autoimmune type 1 diabetes. The incidence of ...

journal_title：Diabetes/metabolism research and reviews

authors： Liu L,Zeng L,Sang D,Lu Z,Shen J

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Increased plasma levels of plasminogen activator inhibitor-1 (PAI-1) have been suggested to be a part of the insulin resistance syndrome, and recent data suggest that adipose tissue participates in the production of PAI-1. We examined the expression and insulin regulation of subcutaneous adipose tissue PAI-1 ...

journal_title：Diabetes/metabolism research and reviews

authors： Koistinen HA,Dusserre E,Ebeling P,Vallier P,Koivisto VA,Vidal H

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Cyclosporin A (CyA) may induce acute nephrotoxicity. The question has been raised of the possible long-term unfavorable course of CyA-induced lesions. Advantage was taken of a large cohort of diabetic patients treated for several months using moderate CyA dosage to evaluate the long-term evolution of renal f...

journal_title：Diabetes/metabolism research and reviews

authors： Assan R,Blanchet F,Feutren G,Timsit J,Larger E,Boitard C,Amiel C,Bach JF

更新日期：2002-11-01 00:00:00

abstract：:Diabetes is a group of metabolic diseases characterized by elevated blood glucose levels that drive the development of life-threatening complications. Diabetes results from a situation of insufficient insulin action, either by deficient production of the hormone by the pancreas, or by the development of insulin resist...

journal_title：Diabetes/metabolism research and reviews

authors： Castaño C,Novials A,Párrizas M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Lispro Mix 25% insulin lispro/75% insulin lispro protamine (LM25) and Lispro Mix 50% insulin lispro/50% insulin lispro protamine (LM50) were compared as starter insulins in East Asian patients with type 2 diabetes. METHODS:Phase 4, open-label, randomized trial conducted in China, Japan, Korea, and Turkey. S...

journal_title：Diabetes/metabolism research and reviews

authors： Watada H,Su Q,Li PF,Iwamoto N,Qian L,Yang WY

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To examine the prognostic implications of diabetes mellitus (DM) and the importance of glycemic control during hospitalization for infectious diseases. METHODS:Historical prospectively collected data of patients hospitalized between 2011 and 2013. Infection-related hospitalizations were classified according ...

journal_title：Diabetes/metabolism research and reviews

authors： Akirov A,Diker-Cohen T,Masri-Iraqi H,Duskin-Bitan H,Shimon I,Gorshtein A

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Treatment with DiaPep277, a peptide derived from HSP60, has been shown to preserve beta-cell function in non-obese diabetic mouse (NOD) mice and in a trial with newly diagnosed human patients with type 1 diabetes treated over a 10-month period. This article extends the clinical trial observations to a total ...

journal_title：Diabetes/metabolism research and reviews

authors： Raz I,Avron A,Tamir M,Metzger M,Symer L,Eldor R,Cohen IR,Elias D

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:This study examined whether temporal trends exist in treatment of patients with type 2 diabetes (T2D) and quality of diabetes care after implementation of quality improvement initiative in primary care setting. METHODS:We conducted a population-based retrospective cohort study of 202,284 patients with T2D w...

journal_title：Diabetes/metabolism research and reviews

authors： Wong CKH,Fung CSC,Yu EYT,Wan EYF,Chan AKC,Lam CLK

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Physical exercise provides health benefits for people with type 2 diabetes mellitus, partly by enhancing skeletal muscle insulin action. We tested the hypothesis that changes in expression of key genes in skeletal muscles relate to exercise-induced improvements in type 2 diabetic patients. METHODS:We determ...

journal_title：Diabetes/metabolism research and reviews

authors： Fritz T,Krämer DK,Karlsson HK,Galuska D,Engfeldt P,Zierath JR,Krook A

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Cross-sectional and family studies identified angiotensin-converting enzyme (ACE) gene as a risk factor for diabetic nephropathy (DN). The contribution of ACE gene variants to DN development and progression is controversial and varies among different ethnic/racial groups. METHODS:We investigated the associa...

journal_title：Diabetes/metabolism research and reviews

authors： Ezzidi I,Mtiraoui N,Kacem M,Chaieb M,Mahjoub T,Almawi WY

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Visceral adiposity index (VAI) is a novel marker of visceral adipose tissue accumulation and dysfunction. The study aim was to explore the association of VAI with the 10-year type 2 diabetes mellitus (T2DM) incidence in apparently healthy individuals and compare its T2DM predictive ability against common ant...

journal_title：Diabetes/metabolism research and reviews

authors： Koloverou E,Panagiotakos DB,Kyrou I,Stefanadis C,Chrysohoou C,Georgousopoulou EN,Skoumas I,Tousoulis D,Pitsavos C,ATTICA Study group.

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Periodontal disease is a frequent complication of diabetes in adults, and both conditions are associated with systemic inflammatory states. This systematic review and meta-analysis was conducted to establish the relative severity of periodontal disease risk markers in children and adolescents with type 1 dia...

journal_title：Diabetes/metabolism research and reviews

authors： Jensen E,Allen G,Bednarz J,Couper J,Peña A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:We aimed to predict the incidence of obesity in a Korean population using a genetic risk score (GRS) constructed with obesity-related single nucleotide polymorphisms (SNPs) along with an oxidative stress score (OSS). METHODS:A total of 9460 Korean subjects and 356 974 SNPs were included. The GRS was constru...

journal_title：Diabetes/metabolism research and reviews

authors： Park S,Yoo HJ,Jee SH,Lee JH,Kim M

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:A nested case-control (NCC) design within a prospective cohort study can realize substantial benefits for biomarker studies. In this context, it is natural to consider the sample availability in the selection of controls to minimize data loss when implementing the design. However, this violates the randomnes...

journal_title：Diabetes/metabolism research and reviews

authors： Lee HS,Lynch KF,Krischer JP,TEDDY Study Group.

更新日期：2020-01-01 00:00:00

abstract：:Rising rates of diabetes in pregnancy have led to an escalation in research in this area. As in any area of clinical research, definitions of outcomes vary from study to study, making it difficult to compare research findings and draw conclusions. Our aim was to compile and create a repository of definitions, which co...

journal_title：Diabetes/metabolism research and reviews

authors： International Association of Diabetes in Pregnancy Study Group (IADPSG) Working Group on Outcome Definitions.,Feig DS,Corcoy R,Jensen DM,Kautzky-Willer A,Nolan CJ,Oats JJ,Sacks DA,Caimari F,McIntyre HD

更新日期：2015-10-01 00:00:00

abstract：:There is strong evidence that the avoidance of hyperglycemia is essential inoptimizing pregnancy outcome in type 1 diabetes. The price to pay is a striking increase in severe hypoglycemia (SH), defined as episodes requiring help from another person. During type 1 diabetic pregnancy, occurrence rates of SH up to 15 tim...

journal_title：Diabetes/metabolism research and reviews

authors： ter Braak EW,Evers IM,Willem Erkelens D,Visser GH

更新日期：2002-03-01 00:00:00

abstract：:Prevention of diabetic foot ulcers is important to reduce the burden of diabetic foot disease. However, we found that ulcer prevention is underexposed in research and clinical practice. Barriers to explain this are seen in patient's goal-setting; in the lack of interdisciplinary teams for ulcer prevention; in sample s...

journal_title：Diabetes/metabolism research and reviews

authors： Van Netten JJ,Woodburn J,Bus SA

更新日期：2020-03-01 00:00:00

abstract：:The intestinal microbiota has come to be considered an additional risk factor for the development of metabolic diseases. Considering the potential role of antimicrobials as modulators of the intestinal microbiota, they have been investigated for use in the adjuvant treatment of obesity and insulin resistance (IR). In ...

journal_title：Diabetes/metabolism research and reviews

authors： Dos Reis SA,do Carmo Gouveia Peluzio M,Bressan J

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Current guidelines recommend screening the feet of diabetic subjects with a 10-g monofilament or tuning fork. We investigated which tests and locations on the feet have the best predictive value regarding 1-year ulcer-free survival in diabetic subjects participating in the prospective Rotterdam Diabetic Foot...

journal_title：Diabetes/metabolism research and reviews

authors： Rinkel WD,van der Oest MJW,Dijkstra DA,Castro Cabezas M,Coert JH

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Childhood obesity is encouraged by low physical activity (PA), time spent using screens (screen time, ST), and by sugar-sweetened beverage consumption (SSBc). It is also influenced by unfavorable parents' characteristics, such as a high body mass index (BMI) and low education level (EL). Our aim was to evalu...

journal_title：Diabetes/metabolism research and reviews

authors： Vinciguerra F,Tumminia A,Roppolo F,Romeo LC,La Spina N,Baratta R,Parrino C,Sciacca L,Vigneri R,Frittitta L

更新日期：2019-11-01 00:00:00

abstract：:The immediate consequences of gestational diabetes on pregnancy are well known but the complications decades later for the mother and child are just now emerging. This trio of papers discuss the long-term consequences of gestational diabetes, the importance of screening this high risk group of women for type 2 diabete...

journal_title：Diabetes/metabolism research and reviews

authors： Feig D

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Sodium-glucose cotransporter 2 (SGLT2) inhibitors could potentially alter calcium and phosphate homeostasis and may increase the risk of bone fracture. METHODS:The current meta-analysis was conducted to investigate the fracture risk among patients with type 2 diabetes mellitus treated with SGLT2 inhibitors....

journal_title：Diabetes/metabolism research and reviews

authors： Ruanpeng D,Ungprasert P,Sangtian J,Harindhanavudhi T

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The genetic basis of the autoimmune disease type 1 diabetes (T1D) has now been largely determined, so now we can compare these findings with emerging genetic knowledge of disorders and phenotypes that have been negatively or positively associated with T1D historically. Here, we assessed the role in T1D of va...

journal_title：Diabetes/metabolism research and reviews

authors： Saleh NM,Raj SM,Smyth DJ,Wallace C,Howson JM,Bell L,Walker NM,Stevens HE,Todd JA

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing in developing countries, but its causes are not known. We aimed to ascertain the prevalence and determinants of NAFLD in a new largely unmedicated population-based cohort from the rapidly gentrifying region of Pinggu, China. METHODS:We ran...

journal_title：Diabetes/metabolism research and reviews

authors： Zhou X,Li Y,Zhang X,Guan YY,Puentes Y,Zhang F,Speliotes EK,Ji L

更新日期：2019-07-01 00:00:00

abstract：:The role of peripheral arterial disease in ulcerated diabetic feet has long been underestimated. Progressive claudication, rest pain and the extent of irreversible tissue loss have frequently been indications for revascularization for neuroischaemic ulcers in diabetic patients. These typical ischaemic symptoms are war...

journal_title：Diabetes/metabolism research and reviews

authors： Apelqvist JA,Lepäntalo MJ

更新日期：2012-02-01 00:00:00

abstract：:The exact cause of the obesity epidemic remains unknown; however, both environmental and genetic factors are involved. People at risk of developing obesity include children with type 1 diabetes mellitus (T1DM), which in turn increases their cardiovascular disease risk. Here, we discuss the clinical and genetic factors...

journal_title：Diabetes/metabolism research and reviews

authors： Łuczyński W,Głowińska-Olszewska B,Bossowski A

更新日期：2016-10-01 00:00:00

abstract：:Rising experimental evidence suggests that thiazolidinediones (TZDs) exert a protective effect on breast cancer. However, studies concerning this issue were inconsistent and limited. Hence, we performed a meta-analysis with data from currently available studies to evaluate the effect of TZDs on breast cancer risk amon...

journal_title：Diabetes/metabolism research and reviews

authors： Du R,Lin L,Cheng D,Xu Y,Xu M,Chen Y,Wang W,Bi Y,Li D,Lu J

更新日期：2018-02-01 00:00:00