Variables affecting penetrance of gastric and duodenal phenotype in familial adenomatous polyposis patients.

abstract：BACKGROUND:Many studies suggest that in chronic hepatitis B virus (HBV) infection regulate T (Treg) cells and interlukin-17-producing T help cells (Th17) are mutually antagonistic in the immune response. This study is aimed to reveal the cell differentiation environment and the significance of Treg and Th17 balance in ...

journal_title：BMC gastroenterology

authors： Xue-Song L,Cheng-Zhong L,Ying Z,Mo-Bin W

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Erdheim-Chester disease (ECD) is a rare multisystem non-Langerhans cell histiocytosis that is characterized histologically by xanthogranulomatous infiltrates and radiologically by symmetrical sclerosis of long bones. The xanthomatous process is characterized by prominent foamy histiocytes staining positive f...

journal_title：BMC gastroenterology

authors： Pan A,Doyle T,Schlup M,Lubcke R,Schultz M

更新日期：2011-06-22 00:00:00

abstract：BACKGROUND:Children with cyclic vomiting syndrome (CVS) have a high degree of maternal inheritance of functional gastrointestinal and neurological disorders. CVS in children is also associated with an increased prevalence of mitochondrial DNA single-nucleotide polymorphisms (mtDNA SNPs) 16519 T and 3010A. Preliminary d...

journal_title：BMC gastroenterology

authors： Venkatesan T,Zaki EA,Kumar N,Sengupta J,Ali M,Malik B,Szabo A,van Tilburg MA,Boles RG

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Necrotic tissue releases high mobility group B1 (HMGB1), and HMGB1 contributes to liver injury. Even though blockade of HMGB1 does not protect against APAP-induced acute liver injury (ALI) at 9 h time point, the later time points are not stud...

journal_title：BMC gastroenterology

authors： Yang R,Zhang S,Cotoia A,Oksala N,Zhu S,Tenhunen J

更新日期：2012-05-08 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is a risk factor for colorectal neoplasms. Our goal is to explore the relationship between NAFLD and colorectal cancer (CRC) and to analyze potential indicators for screening CRC in NAFLD based on clinical big data. METHODS:Demographic information and routine clinica...

journal_title：BMC gastroenterology

authors： Yang R,Chen Y,Chen X

更新日期：2020-06-09 00:00:00

abstract：PURPOSE:To determine the indications for adjuvant chemotherapy (AC) in patients with stage IIa gastric cancer (T3N0M0 and T1N2M0) according to the 7th American Joint Committee on Cancer (AJCC). METHODS:A total of 1593 patients with T3N0M0 or T1N2M0 stage gastric cancer were identified from the Surveillance, Epidemiolo...

journal_title：BMC gastroenterology

authors： Huang ZN,Desiderio J,Chen QY,Zheng CH,Li P,Xie JW,Wang JB,Lin JX,Lu J,Cao LL,Lin M,Tu RH,Lin JL,Zheng HL,Huang CM

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:Imatinib mesylate has been the standard therapeutic treatment for chronic myeloid leukemia, advanced and metastatic gastrointestinal stromal tumor (GIST). It is well tolerated with mild adverse effects. Gynecomastia development during the course of treatment has been rarely reported. METHODS:Ninety-eight pa...

journal_title：BMC gastroenterology

authors： Liu H,Liao G,Yan Z

更新日期：2011-11-02 00:00:00

abstract：BACKGROUND:The impact of viral subtype on the rate of sustained virological response (SVR) to antiviral therapy in patients chronically infected with hepatitis C genotype 1 subtype 1a and 1b has not been extensively investigated. The aim of this study is to determine whether the HCV genotype 1 subtypes 1a and 1b respon...

journal_title：BMC gastroenterology

authors： Pellicelli AM,Romano M,Stroffolini T,Mazzoni E,Mecenate F,Monarca R,Picardi A,Bonaventura ME,Mastropietro C,Vignally P,Andreoli A,Marignani M,D'Ambrosio C,Miglioresi L,Nosotti L,Mitidieri O,Gentilucci UV,Puoti C,Barba

更新日期：2012-11-16 00:00:00

abstract：BACKGROUND:Recent improvements in stone extraction implements and apparatus have lessened the complexity of the endoscopic bile duct stone treatment. However, despite confirmation of complete removal, cases of residual stones have been reported, which can result in recurrent biliary symptoms, cholangitis, and pancreati...

journal_title：BMC gastroenterology

authors： Fujita A,Nakahara K,Michikawa Y,Morita R,Suetani K,Sato J,Igarashi Y,Araki R,Ikeda H,Matsunaga K,Watanabe T,Itoh F

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Transarterial chemoembolization (TACE) is the recommended treatment for hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liver Cancer (BCLC) B-stage, whereas sorafenib is an orally administered small molecule target drug for BCLC C-stage. This updated systemic review and meta-analysis focuses on i...

journal_title：BMC gastroenterology

authors： Li L,Zhao W,Wang M,Hu J,Wang E,Zhao Y,Liu L

更新日期：2018-09-04 00:00:00

abstract：BACKGROUND:Non-adherence to drug therapy is common in Inflammatory Bowel Disease (IBD). Patients' beliefs about treatment have an important influence on adherence. An in-depth understanding of this area is, therefore, important for patient-centred care. The aim of the study was to assess patients' perspectives and beli...

journal_title：BMC gastroenterology

authors： Hall NJ,Rubin GP,Hungin AP,Dougall A

更新日期：2007-06-08 00:00:00

abstract：BACKGROUND:Patients with liver cirrhosis typically exhibit abnormal coagulation parameters in conventional coagulation tests (CCTs). Rotational thromboelastometry (ROTEM) is a holistic blood coagulation assay. This method provides an insight into the global hemostatic capabilities and has been suggested to provide a be...

journal_title：BMC gastroenterology

authors： Seeßle J,Löhr J,Kirchner M,Michaelis J,Merle U

更新日期：2020-08-17 00:00:00

abstract：BACKGROUND:Microcirculatory disturbance is an important factor in the pathogenesis of Inflammatory Bowel Disease (IBD) but there have been few studies in this field. Confocal Laser Endomicroscopy (CLE) has been used over the last 10 years and has made it possible to explore the changes in microcirculation of the coloni...

journal_title：BMC gastroenterology

authors： Tian Y,Zheng Y,Teng G,Li J,Wang H

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:MCAD-deficiency is the most common inborn error of fatty acid oxidation now included in many newborn screening programms using MS/MS. During prolonged catabolic episodes, patients may suffer from metabolic decompensation with dysfunction of liver, skeletal- and heart muscle as well as brain. In anabolism, ne...

journal_title：BMC gastroenterology

authors： Das AM,Drache S,Janzen N,Franke A

更新日期：2012-08-30 00:00:00

abstract：BACKGROUND:Cholelithiasis is the gallstone disease (GSD) where stones are formed in the gallbladder. The main function of the gallbladder is to concentrate bile by the absorption of water and sodium. GSD has high prevalence among elderly adults. There are three major types of gallstones found in patients, White, Black ...

journal_title：BMC gastroenterology

authors： Kleiner O,Ramesh J,Huleihel M,Cohen B,Kantarovich K,Levi C,Polyak B,Marks RS,Mordehai J,Cohen Z,Mordechai S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The role of the crural diaphragm during increased intra-abdominal pressure is not exactly known. We investigated the hypothesis that the crural diaphragm undergoes reflex phasic contraction on elevation of the intra-abdominal pressure with a resulting increase of the lower esophageal pressure and prevention ...

journal_title：BMC gastroenterology

authors： Shafik A,Shafik AA,El Sibai O,Mostafa RM

更新日期：2004-09-30 00:00:00

abstract：BACKGROUND:The assessment of residual gastric volume is common practice in critical care units. However, the effects and safety of discarding or returning gastric aspirates remain uncertain. Therefore, we aimed to evaluate the role of discarding or returning gastric aspirates on the gastric residual volumes in critical...

journal_title：BMC gastroenterology

authors： Wen Z,Xie A,Peng M,Bian L,Wei L,Li M

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Endoscopic treatments, such as endoscopic submucosal dissection (ESD) and laparoscopic gastrectomy, are increasingly used to treat a subset of patients with early gastric cancer (EGC). To achieve successful outcomes, it is very important to accurately determine the lateral extent of the tumor. Therefore, we ...

journal_title：BMC gastroenterology

authors： Lee BE,Kim GH,Park DY,Kim DH,Jeon TY,Park SB,You HS,Ryu DY,Kim DU,Song GA

更新日期：2010-08-23 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with cholestasis as principal symptom. CASE PRESENTATION:A 43-year-old caucasian man was admitted to our hosp...

journal_title：BMC gastroenterology

authors： Gallerani M,Pala M,Fabbian F,De Giorgi A

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Capsule endoscopy (CE) is the preferred diagnostic test of choice in the investigation of obscure gastrointestinal bleeding (OGIB). Although, a conservative strategy is recommended in the short-term, for cases with a negative result from CE, the impact of CE on long-term re-bleeding still remains unclear. He...

journal_title：BMC gastroenterology

authors： Wetwittayakhlang P,Wonglhow J,Netinatsunton N,Chamroonkul N,Piratvisuth T

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:In primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) fatigue is a major clinical problem. Abnormal amino acid (AA) patterns have been implicated in the development of fatigue in several non-hepatological conditions but for PBC and PSC no data are available. This study aimed to identify...

journal_title：BMC gastroenterology

authors： ter Borg PC,Fekkes D,Vrolijk JM,van Buuren HR

更新日期：2005-03-24 00:00:00

abstract：BACKGROUND:Desmoid tumors are a group of benign, invasive, solid tumors that are relatively rare in the general population, but can occur in up to 21 % of patients with Familial Adenomatous Polyposis (FAP). They can be difficult to treat and have high rates of recurrence even after resection. Our goal with this study w...

journal_title：BMC gastroenterology

authors： Slowik V,Attard T,Dai H,Shah R,Septer S

更新日期：2015-07-16 00:00:00

abstract：BACKGROUND:Bowel symptoms are considered indicators of the presence of colorectal cancer and other bowel diseases. Self administered questionnaires that elicit information about lower bowel symptoms have not been assessed for reliability, although this has been done for upper bowel symptoms. Our aim was to develop a se...

journal_title：BMC gastroenterology

authors： Adelstein BA,Irwig L,Macaskill P,Katelaris PH,Jones DB,Bokey L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. Worldwide, 6.3 to 33% of the general populations are estimated to suffer from the disease with even higher prevalence in the group sharing metabo...

journal_title：BMC gastroenterology

authors： Pardhe BD,Shakya S,Bhetwal A,Mathias J,Khanal PR,Pandit R,Shakya J,Joshi HO,Marahatta SB

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Crystal storing histiocytosis is a rare disorder associated with monoclonal gammopathy. In this disease, monoclonal heavy and light chains accumulate in the lysosome of macrophages, leading to histiocytic reaction in different organs. It is secondary to the presence of a small B-cell clone, responsible for m...

journal_title：BMC gastroenterology

authors： Contejean A,Larousserie F,Bouscary D,Dohan A,Deau-Fischer B,Szwebel TA,Dhooge M,Terris B,Vignon M

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:Faecal calprotectin (FC) is one of the most widely used non-invasive tests for the diagnosis and assessment of Crohn's disease (CD) activity. Despite this, factors other than disease activity which affect levels have not been extensively reviewed. This is of importance when using FC in the diagnostic setting...

journal_title：BMC gastroenterology

authors： Mendall MA,Chan D,Patel R,Kumar D

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Haemolytic uraemic syndrome is a rarely seen in adults often leading to critical illness. This case highlights how difficult it can be to establish a diagnosis and treat when a patient presents with bloody diarrhoea. CASE PRESENTATION:A 17-year-old Iraqi man presented to the emergency department with abdomi...

journal_title：BMC gastroenterology

authors： Radhakrishnan ST,Ruban A,Uthayakumar AK,Cohen P,Levy J,Teare J

更新日期：2019-08-28 00:00:00

abstract：BACKGROUND:The oral multi-kinase inhibitor sunitinib malate improves the survival of patients with gastrointestinal stromal tumors (GIST) after the disease progresses or intolerance to imatinib mesylate develops. Urinary fistulae arising during treatment with sunitinib for GIST have not been described. CASE PRESENTATI...

journal_title：BMC gastroenterology

authors： Watanabe K,Otsu S,Morinaga R,Kawano S,Hirashima Y,Sakashita H,Shirao K

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Current literature has demonstrated that host glutamine depletion facilitates tumorigenesis. Likewise, the glutamine transporter SLC38A1 is putatively associated with malignant transformation and tumor progression. Taken together, this forms the premise for undertaking the current study. The twofold aim of t...

journal_title：BMC gastroenterology

authors： Xie J,Li P,Gao HF,Qian JX,Yuan LY,Wang JJ

更新日期：2014-04-09 00:00:00

abstract：BACKGROUND:Increasing evidence elucidating the pathogenic mechanisms of ulcerative colitis (UC) has accumulated and the disease is widely assumed to be the consequence of genetic susceptibility and an abnormal immune response to commensal bacteria. However evidence regarding an infectious etiology in UC remains elusive...

journal_title：BMC gastroenterology

authors： Miner J,Gillan MM,Alex P,Centola M

更新日期：2005-01-24 00:00:00