Fast relapse and high drop out rate of 48 weeks daily interferon monotherapy in HIV-infected patients with chronic hepatitis C.

abstract：BACKGROUND:Nutritional changes during and after tuberculosis treatment have not been well described. We therefore determined the effect of wasting on rate of mean change in lean tissue and fat mass as measured by bioelectrical impedance analysis (BIA), and mean change in body mass index (BMI) during and after tuberculo...

journal_title：BMC infectious diseases

authors： Mupere E,Malone L,Zalwango S,Okwera A,Nsereko M,Tisch DJ,Parraga IM,Stein CM,Mugerwa R,Boom WH,Mayanja HK,Whalen CC,Tuberculosis Research Unit at Case Western Reserve University.

更新日期：2014-01-13 00:00:00

abstract：BACKGROUND:American trypanosomiasis is a major disease and public health issue, caused by the protozoan parasite Trypanosoma cruzi. The prevalence of T. cruzi has not been fully documented, and there are few reports of this issue in Nuevo Leon. The aim of this study was to update the seroprevalence rate of T. cruzi inf...

journal_title：BMC infectious diseases

authors： Molina-Garza ZJ,Rosales-Encina JL,Mercado-Hernández R,Molina-Garza DP,Gomez-Flores R,Galaviz-Silva L

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Acute inflammatory reactions are a frequently occurring, tissue destructing phenomenon in infectious- as well as autoimmune diseases, providing clinical challenges for early diagnosis. In leprosy, an infectious disease initiated by Mycobacterium leprae (M. leprae), these reactions represent the major cause o...

journal_title：BMC infectious diseases

authors： Khadge S,Banu S,Bobosha K,van der Ploeg-van Schip JJ,Goulart IM,Thapa P,Kunwar CB,van Meijgaarden KE,van den Eeden SJ,Wilson L,Kabir S,Dey H,Goulart LR,Lobato J,Carvalho W,Bekele Y,Franken KL,Aseffa A,Spencer JS,Osk

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:Oxidative stress plays a vital role in the pathogenesis of both Sickle Cell Disease (SCD) and Plasmodium falciparum malaria. However, there are limited studies on the effect of P. falciparum malaria infection on oxidative stress in SCD patients. METHODS:A cross-sectional study was undertaken to compare leve...

journal_title：BMC infectious diseases

authors： Atiku SM,Louise N,Kasozi DM

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:Early infant diagnosis of HIV infection is challenging in sub-Saharan Africa, particularly in rural areas, leading to delays in diagnosis and treatment. Use of a point-of-care test would overcome many challenges. This study evaluated the validity of a novel point-of-care p24 antigen detection test (LYNX) in ...

journal_title：BMC infectious diseases

authors： Sutcliffe CG,Mutanga J,Moyo N,Agarwal AK,Schue JL,Hamahuwa M,Palamountain KM,Fisher MJ,Elghanian R,Thuma PE,Moss WJ

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment. Among the associated metabolic factors, hepatic steatosis is characterized by an accumulation of triglycerides in hepatocytes. In the host, genetic d...

journal_title：BMC infectious diseases

authors： Magri MC,Prata TV,Manchiero C,Dantas BP,Mazza CC,Tengan FM

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Although Indonesia has high fatality rate of human A/H5N1 cases, epidemiological and clinical data on influenza virus circulation among humans has been limited. Within Indonesia, Bali province is of interest due to high population densities of humans, pigs and poultry. This study aims to characterize and com...

journal_title：BMC infectious diseases

authors： Adisasmito W,Budayanti S,Aisyah DN,Coker R,Andayani AR,Smith GJD,Rudge JW

更新日期：2019-03-07 00:00:00

abstract：BACKGROUND:China faces a serious HIV epidemic among men who have sex with men (MSM), and a large proportion of new infections are attributed to their regular male sex partners (RP). The objective of this study was to investigate the association between intimate relationship characteristics and HIV-related behaviors amo...

journal_title：BMC infectious diseases

authors： He J,Xu HF,Cheng WB,Zhang SJ,Gu J,Hao YT,Hao C

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) is a major global health problem and remains the leading cause of morbidity and mortality in developing countries. Routinely used TB diagnostic methods, in most endemic areas, are time-consuming, often less-sensitive, expensive and inaccessible to most patients. Therefore, there is an urgen...

journal_title：BMC infectious diseases

authors： Bentaleb EM,Abid M,El Messaoudi MD,Lakssir B,Ressami EM,Amzazi S,Sefrioui H,Ait Benhassou H

更新日期：2016-09-27 00:00:00

abstract：BACKGROUND:The current low access to virological testing to confirm chronic viraemic HCV infection in low- and middle-income countries (LMIC) is limiting the rollout of hepatitis C (HCV) care. Existing tests are complex, costly and require sophisticated laboratory infrastructure. Diagnostic manufacturers need guidance ...

journal_title：BMC infectious diseases

authors： Ivanova Reipold E,Easterbrook P,Trianni A,Panneer N,Krakower D,Ongarello S,Roberts T,Miller V,Denkinger C

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B. pertussis infection alone and those with respiratory viral coinfections. We also a...

journal_title：BMC infectious diseases

authors： Frassanito A,Nenna R,Nicolai A,Pierangeli A,Tozzi AE,Stefanelli P,Carsetti R,Concato C,Schiavoni I,Midulla F,Pertussis study group.

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Cryptococcus neoformans causes meningitis and disseminated infection in healthy individuals, but more commonly in hosts with defective immune responses. Cell-mediated immunity is an important component of the immune response to a great variety of infections, including yeast infections. We aimed to evaluate a...

journal_title：BMC infectious diseases

authors： Rocha KC,Pinhal C,Cavalcanti S,Vidal MS,Toscano M,Moraes-Vasconcelos D,Duarte AJ,Fonseca FL,de Abreu LC,Valenti VE,Grumach AS

更新日期：2012-10-30 00:00:00

abstract：BACKGROUND:Accumulated evidence from epidemiological studies and more recently from randomized controlled trials suggests that male circumcision (MC) may substantially protect against genital HPV infection in men. The purpose of this study was to assess the association between MC and genital HPV infection in men in a l...

journal_title：BMC infectious diseases

authors： Albero G,Villa LL,Lazcano-Ponce E,Fulp W,Papenfuss MR,Nyitray AG,Lu B,Castellsagué X,Abrahamsen M,Smith D,Bosch FX,Salmerón J,Quiterio M,Giuliano AR

更新日期：2013-01-17 00:00:00

abstract：BACKGROUND:Hepatitis E virus (HEV) may be resistant to immunosuppression reduction and ribavirin treatment in kidney transplant recipients because of mutant strains and severe side effects of ribavirin which conduct to dose reduction. Sofosbuvir efficacy is controversial. Peg-interferon 2 alpha (PEG-IFN) is currently c...

journal_title：BMC infectious diseases

authors： Ollivier-Hourmand I,Lebedel L,Lecouf A,Allaire M,Nguyen TTN,Lier C,Dao T

更新日期：2020-07-16 00:00:00

abstract：BACKGROUND:The approval of direct-acting antivirals for Interferon-free treatment revolutionized the therapy of chronic Hepatitis C infection. As of August 2014, two treatment regimens for genotype 1 infection received conditional approval in the European Union: Sofosbuvir and Ribavirin for 24 weeks and Sofosbuvir and ...

journal_title：BMC infectious diseases

authors： Gissel C,Götz G,Mahlich J,Repp H

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Inappropriate antibiotic use is linked to the spread of antimicrobial resistance worldwide, but there are limited systemic data on antibiotic utilization in low- and middle-income countries. The purpose of this study was to evaluate the prevalence and patterns of antibiotic prescription in an ambulatory care...

journal_title：BMC infectious diseases

authors： Zhang HL,Bodinayake C,Wijayaratne GB,Jayatissa P,Piyasiri DLB,Kurukulasooriya R,Sheng T,Nagahawatte A,Woods C,Tillekeratne LG

更新日期：2021-01-21 00:00:00

abstract：BACKGROUND:Factors related to the natural transmission of Ebola virus (EBOV) to humans are still not well defined. Results of previous sero-prevalence studies suggest that circulation of EBOV in human population is common in sub-Saharan Africa. The Efé pygmies living in Democratic Republic of the Congo are known to be ...

journal_title：BMC infectious diseases

authors： Mulangu S,Borchert M,Paweska J,Tshomba A,Afounde A,Kulidri A,Swanepoel R,Muyembe-Tamfum JJ,Van der Stuyft P

更新日期：2016-06-10 00:00:00

abstract：BACKGROUND:Delayed diagnosis and treatment of tuberculosis (TB) results in severe disease and a higher mortality. It also leads to an increased period of infectivity in the community. The objective of this study was to determine the length of delays, and analyze the factors affecting the delay from onset of symptoms of...

journal_title：BMC infectious diseases

authors： Yimer S,Bjune G,Alene G

更新日期：2005-12-12 00:00:00

abstract：BACKGROUND:In Ethiopia, measles case-based surveillance was introduced in 2004 as one strategy for measles control by laboratory confirmation of suspected cases. In this article, epidemiological distribution of laboratory-confirmed measles cases were reported from the Southern Nation Nationalities and Peoples Region (S...

journal_title：BMC infectious diseases

authors： Getahun M,Beyene B,Ademe A,Teshome B,Tefera M,Afework A,HaileMariam Y,Assefa E,Hailegiorgis Y,Asha A

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Evidence has existed for decades that higher doses of rifampin may be more effective, but potentially more toxic, than standard doses used in tuberculosis treatment. Whether increased doses of rifampin could safely shorten treatment remains an open question. METHODS/DESIGN:The HIRIF study is a phase II rand...

journal_title：BMC infectious diseases

authors： Milstein M,Lecca L,Peloquin C,Mitchison D,Seung K,Pagano M,Coleman D,Osso E,Coit J,Vargas Vasquez DE,Sanchez Garavito E,Calderon R,Contreras C,Davies G,Mitnick CD

更新日期：2016-08-27 00:00:00

abstract：BACKGROUND:Recently we developed and validated generic quality indicators that define 'appropriate antibiotic use' in hospitalized adults treated for a (suspected) bacterial infection. Previous studies have shown that with appropriate antibiotic use a reduction of 13% of length of hospital stay can be achieved. Our mai...

journal_title：BMC infectious diseases

authors： van Daalen FV,Prins JM,Opmeer BC,Boermeester MA,Visser CE,van Hest RM,Hulscher ME,Geerlings SE

更新日期：2015-03-19 00:00:00

abstract：BACKGROUND:Nitric oxide (NO*) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO* resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases. METHODS:In this study we evaluated the in vitro toxicity of nitric oxide for the promastigote st...

journal_title：BMC infectious diseases

authors： Giudice A,Camada I,Leopoldo PT,Pereira JM,Riley LW,Wilson ME,Ho JL,de Jesus AR,Carvalho EM,Almeida RP

更新日期：2007-02-22 00:00:00

abstract：BACKGROUND:The swine influenza H1N1 first identified in Mexico, spread rapidly across the globe and is considered the fastest moving pandemic in history. The early phase of an outbreak, in which data is relatively scarce, presents scientific challenges on key issues such as: scale, severity and immunity which are funda...

journal_title：BMC infectious diseases

authors： Roll U,Yaari R,Katriel G,Barnea O,Stone L,Mendelson E,Mandelboim M,Huppert A

更新日期：2011-04-14 00:00:00

abstract：BACKGROUND:As several studies indicated an increase in Lyme disease (LD), notably in neighbouring countries, concerns have arisen regarding the evolution of Lyme disease in Belgium. In order to confirm or infirm the increase of LD in Belgium, we focused on hospital admissions of patients diagnosed with LD between 2000 ...

journal_title：BMC infectious diseases

authors： De Keukeleire M,Vanwambeke SO,Kabamba B,Belkhir L,Pierre P,Luyasu V,Robert A

更新日期：2017-12-05 00:00:00

abstract：BACKGROUND:Syndromic surveillance is increasingly being evaluated for its potential for early warning of increased disease activity in the population. However, interpretation is hampered by the difficulty of attributing a causative pathogen. We described the temporal relationship between laboratory counts of influenza ...

journal_title：BMC infectious diseases

authors： Schindeler SK,Muscatello DJ,Ferson MJ,Rogers KD,Grant P,Churches T

更新日期：2009-11-29 00:00:00

abstract：BACKGROUND:We describe a case of severe Guillain-Barre syndrome (GBS) associated with chronic active hepatitis C and mixed cryoglobulinemia (MC). To our knowledge, this association between GBS and hepatitis C virus (HCV) infection has been rarely reported. CASE PRESENTATION:A 56-year-old man developed symmetrical musc...

journal_title：BMC infectious diseases

authors： Chlilek A,Roger C,Muller L,Carles MJ,Stephan R,Laureillard D,Lavigne JP,Lefrant JY,Sotto A

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:Little is known about the morbidity and mortality of invasive fungal disease (IFD) at a population level. The aim of this study was to determine the incidence, trends and outcomes of IFD in all haematology-oncology patients by linking Victorian hospital data to state-based registries. METHODS:Episodes of IF...

journal_title：BMC infectious diseases

authors： Valentine JC,Morrissey CO,Tacey MA,Liew D,Patil S,Peleg AY,Ananda-Rajah MR

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:Many people have multiple infections at the same time, but the combined contribution of those infections to disease-related mortality is unknown. Registered causes of death offer a unique opportunity to study associations between multiple infections. METHODS:We analysed over 900,000 death certificates that ...

journal_title：BMC infectious diseases

authors： Griffiths EC,Pedersen AB,Fenton A,Petchey OL

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients. METHODS:A tertiary care, University hospital-based prospective intervention study was conducted from December 2015 to December 2017. Patients with dissemi...

journal_title：BMC infectious diseases

authors： Pandey S,Malhotra HS,Garg RK,Malhotra KP,Kumar N,Rizvi I,Jain A,Kohli N,Verma R,Sharma P,Uniyal R,Pandey S

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Herpes simplex virus type 2 (HSV-2), one the most common causes of genital ulcers, appears to increase both the risk of HIV acquisition and HIV transmission. HSV-2/HIV co-infection among pregnant women may increase the risk of perinatal transmission of HIV. This study describes rates of HSV-2 among pregnant ...

journal_title：BMC infectious diseases

authors： Domercant JW,Jean Louis F,Hulland E,Griswold M,Andre-Alboth J,Ye T,Marston BJ

更新日期：2017-08-18 00:00:00