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Microbial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old.

Abstract：

OBJECTIVE:The aim of this study was to examine the microbiological changes in newborn babies with cleft lip palate from birth up to age 3 and to correlate them with their caries levels and mothers' microbiological data and to compare with normal infants. BASIC RESEARCH DESIGN:Prospective. SETTINGS:Marmara University, Faculty of Dentistry, Pediatric Dentistry Clinic, and Şişli Hamidiye Etfal Education and Research Hospital New Born Clinic. PATIENTS/PARTICIPANTS:Cleft lip palate (n = 21) and healthy (n = 13) newborns and their mothers. MATERIAL AND METHODS:Intraoral samples were taken from babies in each group at least 3 times over the 3 years. Saliva samples of the mothers were collected just after the birth of the babies and examined microbiologically. Dental caries was noted as either present or absent. RESULTS:The most frequent microorganisms were candida, found at birth (n = 9, 42%) in cleft palate with or without cleft lip (CP±L) group. The number of babies infected with Lactobacilli were found to be significantly higher in the CP±L group than in the control group at birth ( P = .029) and after eruption of the first primary tooth ( P = .030). Mutans Streptococci were found in 10% of babies with CP±L at birth. Initial caries was identified in 20% of the babies with an oral cleft compared with 0% of the controls after eruption of the first primary incisors. CONCLUSION:The results show that the CP±L babies must be considered as a group with an increased caries risk.

journal_name

Cleft Palate Craniofac J

journal_title

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

authors

Durhan MA,Topcuoglu N,Kulekci G,Ozgentas E,Tanboga I

doi

10.1177/1055665618776428

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

349-356

issue

3

eissn

1055-6656

issn

1545-1569

journal_volume

56

pub_type

杂志文章

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