Investigating knowledge regarding antibiotics and antimicrobial resistance among pharmacy students in Sri Lankan universities.

Abstract:

BACKGROUND:Antimicrobial resistance (AMR) is a major challenge for global health care. Pharmacists play a key role in the health care setting to help support the quality use of medicines. The education, training, and experiences of pharmacy students have the potential to impact on patterns of antibiotic use in community and hospital settings. The aim of this study was to investigate antibiotic use, knowledge of antibiotics and AMR among undergraduate pharmacy students at Sri Lankan universities and to compare this between junior and senior pharmacy student groups. METHODS:A cross-sectional study was conducted at the six universities in Sri Lanka that offer pharmacy undergraduate programmes. All pharmacy students in each university were invited to participate in this study using a self-administered questionnaire with ethics approval. The study instrument comprised five major sections: demographic information, self-reported antibiotic use, knowledge of antibiotic uses in human health, knowledge of AMR and antibiotic use in agriculture. Descriptive data analyses were conducted and Chi-squared analysis was used to explore associations between different variables and level of pharmacy education. RESULTS:Four hundred sixty-six pharmacy students completed the questionnaire. A majority of participants (76%) reported antibiotic use in the past year. More than half (57%) of the junior pharmacy students incorrectly indicated that antibiotic use is appropriate for the management of cold and flu conditions. Senior pharmacy students (n = 206) reported significantly better antibiotic knowledge than junior students (n = 260), p < 0.05. Overall pharmacy students showed good understanding of AMR and their knowledge level increased as the year of pharmacy study increased. CONCLUSIONS:This study found that pharmacy students commonly report using antibiotics. Junior students report some misconceptions about antimicrobials. A comparison between junior and senior pharmacy students suggests that pharmacy education is associated with improved understanding of appropriate antibiotic use and AMR among undergraduate pharmacy students in Sri Lanka.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Sakeena MHF,Bennett AA,Jamshed S,Mohamed F,Herath DR,Gawarammana I,McLachlan AJ

doi

10.1186/s12879-018-3107-8

subject

Has Abstract

pub_date

2018-05-08 00:00:00

pages

209

issue

1

issn

1471-2334

pii

10.1186/s12879-018-3107-8

journal_volume

18

pub_type

杂志文章
  • DNA restriction fragment length polymorphism analysis of Mycobacterium tuberculosis isolates from HIV-seropositive and HIV-seronegative patients in Kampala, Uganda.

    abstract:BACKGROUND:The identification and differentiation of strains of Mycobacterium tuberculosis by DNA fingerprinting has provided a better understanding of the epidemiology and tracing the transmission of tuberculosis. We set out to determine if there was a relationship between the risk of belonging to a group of tuberculo...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-9-12

    authors: Asiimwe BB,Joloba ML,Ghebremichael S,Koivula T,Kateete DP,Katabazi FA,Pennhag A,Petersson R,Kallenius G

    更新日期:2009-02-05 00:00:00

  • Early loss of bone mineral density is correlated with a gain of fat mass in patients starting a protease inhibitor containing regimen: the prospective Lipotrip study.

    abstract:BACKGROUND:HIV-infected patients starting antiretroviral treatment (ART) experience deep and early disorders in fat and bone metabolism, leading to concomitant changes in fat mass and bone mineral density. METHODS:We conducted a prospective study in treatment-naive HIV-infected patients randomized to receive two nucle...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2334-13-293

    authors: Bonnet E,Ruidavets JB,Genoux A,Mabile L,Busato F,Obadia M,Prévoteau F,Marchou B,Massip P,Marion-Latard F,Delpierre C,Bernard J,Perret B

    更新日期:2013-06-28 00:00:00

  • Lomentospora prolificans endocarditis--case report and literature review.

    abstract:BACKGROUND:Lomentospora prolificans (formally Scedosporium prolificans) is an environmental mould with a global distribution. Endocarditis caused by L. prolificans is a rare but serious emerging disease in immunocompromised patients. Prior to this case there have only been eight cases reported in the literature. Diagno...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,评审

    doi:10.1186/s12879-016-1372-y

    authors: Kelly M,Stevens R,Konecny P

    更新日期:2016-01-29 00:00:00

  • Using a community based survey of healthcare seeking behavior to estimate the actual magnitude of influenza among adults in Beijing during 2013-2014 season.

    abstract:BACKGROUND:Due to a lack of survey of health care seeking behavior for influenza, the actual magnitude of influenza in Beijing of China has not been well described. METHODS:During 2013-2014 influenza season, two cross-sectional household surveys were carried out respectively during the epidemic and non-epidemic season...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2217-z

    authors: Wang X,Wu S,Yang P,Li H,Chu Y,Tang Y,Hua W,Zhang H,Li C,Wang Q

    更新日期:2017-02-03 00:00:00

  • Long-term follow-up of HCV infected kidney transplant recipients receiving direct-acting antiviral agents: a single-center experience in China.

    abstract:BACKGROUND:Long-term outcome of DAAs therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort of HCV-infected kidney transplant recipients. METHODS:Single-center and retrospective study of HCV-infected kidney transplant recipients initiating an DAAs regimen between January...

    journal_title:BMC infectious diseases

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12879-019-4217-7

    authors: Zhang J,Sun W,Lin J,Tian Y,Ma L,Zhang L,Zhu Y,Qiu W

    更新日期:2019-07-19 00:00:00

  • Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide.

    abstract:BACKGROUND:For approximately 24 years the AIDS pandemic has claimed approximately 30 million lives, causing approximately 14,000 new HIV-1 infections daily worldwide in 2003. About 80% of infections occur by heterosexual transmission. In the absence of vaccines, topical microbicides, expected to block virus transmissio...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-4-41

    authors: Neurath AR,Strick N,Li YY,Debnath AK

    更新日期:2004-10-14 00:00:00

  • High prevalence of Bordetella pertussis in children under 5 years old hospitalized with acute respiratory infections in Lima, Peru.

    abstract:BACKGROUND:Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate. METHODS:A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses of acute ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-1287-z

    authors: Pavic-Espinoza I,Bendezú-Medina S,Herrera-Alzamora A,Weilg P,Pons MJ,Aguilar-Luis MA,Petrozzi-Helasvuo V,del Valle Mendoza J

    更新日期:2015-12-02 00:00:00

  • Performance of serological tests PGL1 and NDO-LID in the diagnosis of leprosy in a reference Center in Brazil.

    abstract:BACKGROUND:Early detection of leprosy and multidrug therapy are crucial to achieve zero transmission and zero grade II incapacities goals of World Health Organization. Leprosy is difficult to diagnose because clinical forms vary and there are no gold standard methods to guide clinicians. The serological rapid tests aid...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3653-0

    authors: Leturiondo AL,Noronha AB,do Nascimento MOO,Ferreira CO,Rodrigues FDC,Moraes MO,Talhari C

    更新日期:2019-01-07 00:00:00

  • Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcome.

    abstract:BACKGROUND:Clostridium difficile-associated disease (CDAD) is a serious nosocomial infection, however few studies have assessed CDAD outcome in the intensive care unit (ICU). We evaluated the epidemiology, clinical course and outcome of hospital-acquired CDAD in the critical care setting. METHODS:We performed a histor...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-7-42

    authors: Marra AR,Edmond MB,Wenzel RP,Bearman GM

    更新日期:2007-05-21 00:00:00

  • Possible explanations for why some countries were harder hit by the pandemic influenza virus in 2009 - a global mortality impact modeling study.

    abstract:BACKGROUND:A global pandemic mortality study found prominent regional mortality variations in 2009 for Influenza A(H1N1)pdm09. Our study attempts to identify factors that explain why the pandemic mortality burden was high in some countries and low in others. METHODS:As a starting point, we identified possible risk fac...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2730-0

    authors: Morales KF,Paget J,Spreeuwenberg P

    更新日期:2017-09-25 00:00:00

  • Management of amphotericin-induced phlebitis among HIV patients with cryptococcal meningitis in a resource-limited setting: a prospective cohort study.

    abstract:BACKGROUND:Amphotericin-induced phlebitis is a common infusion-related reaction in patients managed for cryptococcal meningitis. High-quality nursing care is critical component to successful cryptococcosis treatment. We highlight the magnitude and main approaches in the management of amphotericin-induced phlebitis and ...

    journal_title:BMC infectious diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1186/s12879-019-4209-7

    authors: Ahimbisibwe C,Kwizera R,Ndyetukira JF,Kugonza F,Sadiq A,Hullsiek KH,Williams DA,Rhein J,Boulware DR,Meya DB

    更新日期:2019-06-26 00:00:00

  • Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic.

    abstract:BACKGROUND:Confirmed H1N1 cases during late spring and summer 2009 in various countries showed a substantial age shift between importations and local transmission cases, with adults mainly responsible for seeding unaffected regions and children most frequently driving community outbreaks. METHODS:We introduce a multi-...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-176

    authors: Apolloni A,Poletto C,Colizza V

    更新日期:2013-04-15 00:00:00

  • Pharmacokinetics of quinacrine in the treatment of prion disease.

    abstract:BACKGROUND:Prion diseases are caused by the accumulation of an aberrantly folded isoform of the prion protein, designated PrPSc. In a cell-based assay, quinacrine inhibits the conversion of normal host prion protein (PrPC) to PrPSc at a half-maximal concentration of 300 nM. While these data suggest that quinacrine may ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-4-53

    authors: Yung L,Huang Y,Lessard P,Legname G,Lin ET,Baldwin M,Prusiner SB,Ryou C,Guglielmo BJ

    更新日期:2004-11-29 00:00:00

  • Recurrent severe invasive pneumococcal disease in an adult with previously unknown hyposplenia.

    abstract:BACKGROUND:The risk of life-threatening and invasive infections with encapsulated bacteria is increased in patients with hyposplenia or asplenia. We report a case of recurrent invasive pneumococcal meningitis in a woman with previous unknown hyposplenia. She was vaccinated after the first episode of meningitis and deve...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-0883-2

    authors: Ballegaard VC,Schejbel L,Hoffmann S,Kantsø B,Fischer CP

    更新日期:2015-04-02 00:00:00

  • Perspectives on male partner notification and treatment for syphilis among antenatal women and their partners in Kampala and Wakiso districts, Uganda.

    abstract:BACKGROUND:Syphilis screening can be successfully integrated into antenatal clinics, and potentially avert significant morbidity and mortality to unborn infants. A minority of male partners report for testing and treatment, increasing the likelihood of reinfection. We conducted a qualitative study to understand factors...

    journal_title:BMC infectious diseases

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12879-019-3695-y

    authors: Nakku-Joloba E,Kiguli J,Kayemba CN,Twimukye A,Mbazira JK,Parkes-Ratanshi R,Birungi M,Kyenkya J,Byamugisha J,Gaydos C,Manabe YC

    更新日期:2019-02-06 00:00:00

  • Incidence of herpes zoster and associated events including stroke--a population-based cohort study.

    abstract:BACKGROUND:More detailed understanding of herpes zoster (HZ) is called for in the context of an increasing observed frequency of disease, and ongoing discussions regarding potential consequences of the disease. Thus, population-based data on incidence and complications of HZ are needed. METHODS:We conducted a register...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-1170-y

    authors: Sundström K,Weibull CE,Söderberg-Löfdal K,Bergström T,Sparén P,Arnheim-Dahlström L

    更新日期:2015-10-31 00:00:00

  • Temporal trends of β-haemolytic streptococcal osteoarticular infections in western Norway.

    abstract:BACKGROUND:Beta-haemolytic streptococci are important contributors to the global burden of osteoarticular infections (OAI). Knowledge on the disease traits specific for streptococcal OAI, however, remains scarce. We wished to explore temporal trends of OAI caused by Group A Streptococci (GAS), Group B Streptococci (GBS...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1874-7

    authors: Oppegaard O,Skrede S,Mylvaganam H,Kittang BR

    更新日期:2016-10-04 00:00:00

  • Multilevel ordinal model for CD4 count trends in seroconversion among South Africa women.

    abstract:BACKGROUND:Ordinal health longitudinal response variables have distributions that make them unsuitable for many popular statistical models that assume normality. We present a multilevel growth model that may be more suitable for medical ordinal longitudinal outcomes than are statistical models that assume normality and...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05159-4

    authors: Dessie ZG,Zewotir T,Mwambi H,North D

    更新日期:2020-06-23 00:00:00

  • Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses.

    abstract:BACKGROUND:Dengue is a major public health problem in tropical and subtropical countries. Rapid and easy diagnosis of dengue can assist patient triage and care-management. The detection of DENV NS1 on rapid lateral flow tests offers a fast route to a presumptive dengue diagnosis but careful evaluations are urgently nee...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-10-142

    authors: Tricou V,Vu HT,Quynh NV,Nguyen CV,Tran HT,Farrar J,Wills B,Simmons CP

    更新日期:2010-05-28 00:00:00

  • Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies.

    abstract::Detection of the Mycobacterium tuberculosis cell wall antigen lipoarabinomannan (LAM) in urine permits diagnoses of tuberculosis (TB) to be made in HIV-infected patients with advanced immunodeficiency. This can be achieved at the point-of-care within just 30 minutes using the Determine TB-LAM, which is a commercially ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-407

    authors: Lawn SD,Dheda K,Kerkhoff AD,Peter JG,Dorman S,Boehme CC,Nicol MP

    更新日期:2013-09-03 00:00:00

  • Retention in care and adherence to HIV and AIDS treatment in Anambra State Nigeria.

    abstract:BACKGROUND:Retaining patients on antiretroviral treatment in care is critical to sustaining the 90:90:90 vision. Nigeria has made some progress in placing HIV-positive patients on treatment. In an effort to increase access to treatment, ART decentralization has been implemented in the country. This is aimed at strength...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4293-8

    authors: Umeokonkwo CD,Onoka CA,Agu PA,Ossai EN,Balogun MS,Ogbonnaya LU

    更新日期:2019-07-22 00:00:00

  • Association of Trypanosoma cruzi infection with risk factors and electrocardiographic abnormalities in northeast Mexico.

    abstract:BACKGROUND:American trypanosomiasis is a major disease and public health issue, caused by the protozoan parasite Trypanosoma cruzi. The prevalence of T. cruzi has not been fully documented, and there are few reports of this issue in Nuevo Leon. The aim of this study was to update the seroprevalence rate of T. cruzi inf...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-14-117

    authors: Molina-Garza ZJ,Rosales-Encina JL,Mercado-Hernández R,Molina-Garza DP,Gomez-Flores R,Galaviz-Silva L

    更新日期:2014-03-01 00:00:00

  • Estimation of Zika virus prevalence by appearance of microcephaly.

    abstract:BACKGROUND:There currently is a severe Zika Virus (ZIKV) epidemic in Brazil and other South American countries. Due to international travel, this poses severe public health risk of ZIKV importation to other countries. We estimate the prevalence of ZIKV in an import region by the time a microcephaly case is detected, si...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-2076-z

    authors: Saad-Roy CM,van den Driessche P,Ma J

    更新日期:2016-12-12 00:00:00

  • Multi-complexity measures of heart rate variability and the effect of vasopressor titration: a prospective cohort study of patients with septic shock.

    abstract:BACKGROUND:Septic shock is a common and often devastating syndrome marked by severe cardiovascular dysfunction commonly managed with vasopressors. Whether markers of heart rate complexity before vasopressor up-titration could be used to predict success of the up-titration is not known. METHODS:We studied patients with...

    journal_title:BMC infectious diseases

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12879-016-1896-1

    authors: Brown SM,Sorensen J,Lanspa MJ,Rondina MT,Grissom CK,Shahul S,Mathews VJ

    更新日期:2016-10-10 00:00:00

  • Healthcare-associated infections: bacteriological characterization of the hospital surfaces in the University Hospital of Abomey-Calavi/so-ava in South Benin (West Africa).

    abstract:BACKGROUND:Healthcare-associated infections have become a public health problem, creating a new burden on medical care in hospitals. The emergence of multidrug-resistant bacteria poses a difficult task for physicians, who have limited therapeutic options. The dissemination of pathogens depends on "reservoirs", the diff...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3648-x

    authors: Afle FCD,Agbankpe AJ,Johnson RC,Houngbégnon O,Houssou SC,Bankole HS

    更新日期:2019-01-07 00:00:00

  • Amygdalin promotes the activity of T cells to suppress the progression of HBV-related hepatocellular carcinoma via the JAK2/STAT3 signaling pathway.

    abstract:BACKGROUND:Hepatitis B virus (HBV) infection is a high-risk factor of hepatocellular carcinoma (HCC). Cellular immune responses are essential for HCC development, and the CD4+ and CD8+ T subtypes are identified as the primary anti-tumor immune cells. In the study, we investigated the effect and mechanism of amygdalin i...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05713-0

    authors: Wang R,Zhang D,Sun K,Peng J,Zhu W,Yin S,Tang D,Wu Y

    更新日期:2021-01-12 00:00:00

  • Prevalence and Incidence of Smear-Positive Pulmonary Tuberculosis in the Hetosa District of Arsi Zone, Oromia Regional State of Central Ethiopia.

    abstract:BACKGROUND:The real burden of smear-positive (PTB+) and bacteriologically confirmed tuberculosis (BCTB) in Ethiopia is not known. Thus, the aim of this community-based study was to measure the prevalence and incidence of tuberculosis in the Hetosa District of Oromia Region, Ethiopia. METHODS:First, a population-based ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2321-0

    authors: Hamusse S,Demissie M,Teshome D,Hassen MS,Lindtjørn B

    更新日期:2017-03-16 00:00:00

  • Decreasing trends, and geographical variation in outpatient antibiotic use: a population-based study in Central Denmark.

    abstract:BACKGROUND:Antimicrobial overuse and misuse of broad-spectrum antibiotics increases the risk for antimicrobial resistance. Investigating unwarranted variation in antibiotic prescription has therefore gained global priority. METHODS:We examined recent time trends in the utilization of narrow- and broad-spectrum antibio...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-3964-9

    authors: Kristensen PK,Johnsen SP,Thomsen RW

    更新日期:2019-04-24 00:00:00

  • Genomic characterization of MDR/XDR-TB in Kazakhstan by a combination of high-throughput methods predominantly shows the ongoing transmission of L2/Beijing 94-32 central Asian/Russian clusters.

    abstract:BACKGROUND:Kazakhstan remains a high-burden TB prevalence country with a concomitent high-burden of multi-drug resistant tuberculosis. For this reason, we performed an in depth genetic diversity and population structure characterization of Mycobacterium tuberculosis complex (MTC) genetic diversity in Kazakhstan with bo...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4201-2

    authors: Klotoe BJ,Kacimi S,Costa-Conceicão E,Gomes HM,Barcellos RB,Panaiotov S,Haj Slimene D,Sikhayeva N,Sengstake S,Schuitema AR,Akhalaia M,Alenova A,Zholdybayeva E,Tarlykov P,Anthony R,Refrégier G,Sola C

    更新日期:2019-06-24 00:00:00

  • Whole-genome enrichment and sequencing of Chlamydia trachomatis directly from clinical samples.

    abstract:BACKGROUND:Chlamydia trachomatis is a pathogen of worldwide importance, causing more than 100 million cases of sexually transmitted infections annually. Whole-genome sequencing is a powerful high resolution tool that can be used to generate accurate data on bacterial population structure, phylogeography and mutations a...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-014-0591-3

    authors: Christiansen MT,Brown AC,Kundu S,Tutill HJ,Williams R,Brown JR,Holdstock J,Holland MJ,Stevenson S,Dave J,Tong CY,Einer-Jensen K,Depledge DP,Breuer J

    更新日期:2014-11-12 00:00:00