Wirsung atraumatic rupture in patient with pancreatic pseudocysts: a case presentation.


BACKGROUND:Pancreatic duct disruption is a challenging condition leading to pancreatic juice leakage and consequently to pancreatic fluid collections. The manifestations of pancreatic main duct leak include pseudocysts, walled-off necrosis, pancreatic fistulas, ascites, pleural and pericardial effusions. Pseudocyst formation is the most frequent outcome of a pancreatic duct leak. CASE PRESENTATION:We describe a case of a 64-year old man with large multiple pancreatic cysts discovered for progressive jaundice and significant weight loss in the absence of a previous episode of acute pancreatitis. Computed tomography scan showed lesion with thick enhancing walls. The main cyst dislocated the stomach and the duodenum inducing intra and extrahepatic bile ducts enlargement. Magnetic resonance cholangiopancreatography revealed a communication between the main pancreatic duct and the cystic lesions due to Wirsung duct rupture. Endoscopic ultrasound guided fine needle aspiration cytology did not show neoplastic cells and cyst fluid analysis revealed high amylase concentration. Preoperative exams were suggestive but not conclusive for a benign lesion. Laparotomy was necessary to confirm the presence of large communicating pseudocysts whose drainage was performed by cystogastrostomy. Histology confirmed the inflammatory nature of the cyst wall. Subsequently, the patient had progressive jaundice resolution. CONCLUSION:Pancreatic cystic masses include several pathological entities, ranging from benign to malignant lesions. Rarely pseudocysts present as complex cystic pancreatic lesions with biliary compression in absence of history of acute pancreatitis. We describe the rare case of multiple pancreatic pseudocysts due to Wirsung duct rupture in absence of previous trauma or acute pancreatitis. Magnetic resonance showed the presence of communication with the main pancreatic duct and endoscopic ultrasound fine needle aspiration suggested the benign nature of the lesion.


BMC Gastroenterol


BMC gastroenterology


Gerosa M,Chiarelli M,Guttadauro A,De Simone M,Tagliabue F,Costa M,Terragni S,Cioffi U




Has Abstract


2018-04-23 00:00:00












  • Value of routine test for identifying colorectal cancer from patients with nonalcoholic fatty liver disease.

    abstract:BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is a risk factor for colorectal neoplasms. Our goal is to explore the relationship between NAFLD and colorectal cancer (CRC) and to analyze potential indicators for screening CRC in NAFLD based on clinical big data. METHODS:Demographic information and routine clinica...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Yang R,Chen Y,Chen X

    更新日期:2020-06-09 00:00:00

  • Oral versus intravenous proton pump inhibitors in preventing re-bleeding for patients with peptic ulcer bleeding after successful endoscopic therapy.

    abstract:BACKGROUND:High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy. Whether oral proton pump inhibitor can replace intravenous proton pump inhibitor in this setting is unknown. This study aims to compare the clinical efficacy of oral and in...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,随机对照试验


    authors: Yen HH,Yang CW,Su WW,Soon MS,Wu SS,Lin HJ

    更新日期:2012-06-08 00:00:00

  • A colonic mass revealing a disseminated crystal storing histiocytosis secondary to indolent multiple myeloma: a case report with literature review.

    abstract:BACKGROUND:Crystal storing histiocytosis is a rare disorder associated with monoclonal gammopathy. In this disease, monoclonal heavy and light chains accumulate in the lysosome of macrophages, leading to histiocytic reaction in different organs. It is secondary to the presence of a small B-cell clone, responsible for m...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Contejean A,Larousserie F,Bouscary D,Dohan A,Deau-Fischer B,Szwebel TA,Dhooge M,Terris B,Vignon M

    更新日期:2020-07-31 00:00:00

  • Do gastrointestinal and respiratory signs and symptoms correlate with the severity of gastroesophageal reflux?

    abstract:BACKGROUND:Gastroesophageal reflux (GER) is a disorder that is common by seen in childhood and may lead to severe complications. In this study, we ascertained the incidence of GER among the children who had typical and atypical complaints of GER and whether there was a difference between two groups comparing the findin...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Uzun H,Alagoz D,Okur M,Dikici B,Kocabay K,Senses DA,Ozkan A,Kaya M

    更新日期:2012-03-21 00:00:00

  • Overexpression of SLC38A1 is associated with poorer prognosis in Chinese patients with gastric cancer.

    abstract:BACKGROUND:Current literature has demonstrated that host glutamine depletion facilitates tumorigenesis. Likewise, the glutamine transporter SLC38A1 is putatively associated with malignant transformation and tumor progression. Taken together, this forms the premise for undertaking the current study. The twofold aim of t...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Xie J,Li P,Gao HF,Qian JX,Yuan LY,Wang JJ

    更新日期:2014-04-09 00:00:00

  • GERD assessment including pH metry predicts a high response rate to PPI standard therapy.

    abstract:BACKGROUND:Inadequate response to proton pump inhibitor (PPI) therapy in patients with gastroesophageal reflux disease (GERD) is reported in up to 40%. Patients with non erosive reflux disease (NERD) have lower response rates compared to patients with erosive reflux disease (ERD); pH metry contributes to GERD diagnosis...

    journal_title:BMC gastroenterology

    pub_type: 临床试验,杂志文章


    authors: Kandulski A,Peitz U,Mönkemüller K,Neumann H,Weigt J,Malfertheiner P

    更新日期:2013-01-16 00:00:00

  • Slug down-regulation by RNA interference inhibits invasion growth in human esophageal squamous cell carcinoma.

    abstract:BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive carcinomas of the gastrointestinal tract. We assessed the relevance of Slug in measuring the invasive potential of ESCC cells in vitro and in vivo in immunodeficient mice. METHODS:We utilized RNA interference to knockdown Slug gene expr...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Tang P,Yu Z,Zhang K,Wang Y,Ma Z,Zhang S,Chen D,Zhou Y

    更新日期:2011-05-20 00:00:00

  • A multi-country study of intussusception in children under 2 years of age in Latin America: analysis of prospective surveillance data.

    abstract:BACKGROUND:Intussusception (IS) is a form of acute intestinal obstruction that occurs mainly in infants and is usually of unknown cause. An association between IS and the first licensed rotavirus vaccine, a reassortant-tetravalent, rhesus-based rotavirus vaccine (RRV-TV), led to the withdrawal of the vaccine. New rotav...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Sáez-Llorens X,Velázquez FR,Lopez P,Espinoza F,Linhares AC,Abate H,Nuñez E,Venegas G,Vergara R,Jimenez AL,Rivera M,Aranza C,Richardson V,Macias-Parra M,Palacios GR,Rivera L,Ortega-Barria E,Cervantes Y,Rüttimann R,Ru

    更新日期:2013-05-27 00:00:00

  • Chronic active EBV infection in refractory enteritis with longitudinal ulcers with a cobblestone appearance: an autopsied case report.

    abstract:BACKGROUND:Chronic active Epstein-Barr virus infection (CAEBV) is defined as Epstein-Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Aihara Y,Moriya K,Shimozato N,Nagamatsu S,Kobayashi S,Uejima M,Matsuo H,Ishida E,Yagi H,Nakatani T,Yoshiji H,Kikuchi E

    更新日期:2021-01-06 00:00:00

  • Rotational thrombelastometry (ROTEM) improves hemostasis assessment compared to conventional coagulation test in ACLF and Non-ACLF patients.

    abstract:BACKGROUND:Patients with liver cirrhosis typically exhibit abnormal coagulation parameters in conventional coagulation tests (CCTs). Rotational thromboelastometry (ROTEM) is a holistic blood coagulation assay. This method provides an insight into the global hemostatic capabilities and has been suggested to provide a be...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Seeßle J,Löhr J,Kirchner M,Michaelis J,Merle U

    更新日期:2020-08-17 00:00:00

  • Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis.

    abstract:BACKGROUND:Efforts to identify cell sources and approaches for cell therapy of liver diseases are ongoing, taking into consideration the limits recognized for adult liver tissue and for other forms of stem cells. In the present study, we described the first procedure of via hepatic artery transplantation of human fetal...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Cardinale V,Carpino G,Gentile R,Napoletano C,Rahimi H,Franchitto A,Semeraro R,Nuti M,Onori P,Berloco PB,Rossi M,Bosco D,Brunelli R,Fraveto A,Napoli C,Torrice A,Gatto M,Venere R,Bastianelli C,Aliberti C,Salvatori F

    更新日期:2014-12-04 00:00:00

  • Bleeding in patients who underwent scheduled second-look endoscopy 5 days after endoscopic submucosal dissection for gastric lesions.

    abstract:BACKGROUND:Bleeding after endoscopic submucosal dissection (ESD) in antithrombotic drug users is still one of the important issues to be solved. We performed scheduled second-look endoscopy (SLE) 5 days after ESD, when the resumption of antithrombotic agents is assumed to have achieved a steady state, rather than on th...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Izumikawa K,Iwamuro M,Inaba T,Ishikawa S,Kuwaki K,Sakakihara I,Yamamoto K,Takahashi S,Tanaka S,Wato M,Okada H

    更新日期:2018-04-10 00:00:00

  • A case report of prostate cancer metastasis to the stomach resembling undifferentiated-type early gastric cancer.

    abstract:BACKGROUND:Occurrence of metastatic cancer to the stomach is rare, particularly in patients with prostate cancer. Gastric metastasis generally presents as a solitary and submucosal lesion with a central depression. CASE PRESENTATION:We describe a case of gastric metastasis arising from prostate cancer, which is almost...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Inagaki C,Suzuki T,Kitagawa Y,Hara T,Yamaguchi T

    更新日期:2017-08-07 00:00:00

  • Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised controlled trial.

    abstract:BACKGROUND:Studies have demonstrated usefulness of cognitive-behavioural therapy (CBT) in managing distress in inflammatory bowel disease (IBD); however, few have focused on IBD course. The present trial aimed to investigate whether adding CBT to standard treatment prolongs remission in IBD in comparison to standard th...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,随机对照试验


    authors: Mikocka-Walus A,Bampton P,Hetzel D,Hughes P,Esterman A,Andrews JM

    更新日期:2015-05-02 00:00:00

  • Green tea consumption and risk of esophageal cancer: a meta-analysis of epidemiologic studies.

    abstract:BACKGROUND:Green tea has shown the role of chemoprevention for cancer. Recently, several studies suggested that green tea intake may have effect on esophageal cancer risk, whereas the results were inconsistent. METHODS:We performed a meta-analysis of all English and Chinese language studies of green tea consumption an...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,meta分析


    authors: Zheng P,Zheng HM,Deng XM,Zhang YD

    更新日期:2012-11-21 00:00:00

  • Imbalanced mucosal microcirculation in the remission stage of ulcerative colitis using probe-based confocal laser endomicroscopy.

    abstract:BACKGROUND:Microcirculatory disturbance is an important factor in the pathogenesis of Inflammatory Bowel Disease (IBD) but there have been few studies in this field. Confocal Laser Endomicroscopy (CLE) has been used over the last 10 years and has made it possible to explore the changes in microcirculation of the coloni...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Tian Y,Zheng Y,Teng G,Li J,Wang H

    更新日期:2019-07-01 00:00:00

  • Follow-up of pediatric celiac disease: value of antibodies in predicting mucosal healing, a prospective cohort study.

    abstract:BACKGROUND:In diagnosing celiac disease (CD), serological tests are highly valuable. However, their role in following up children with CD after prescription of a gluten-free diet is unclear. This study aimed to compare the performance of antibody tests in predicting small-intestinal mucosal status in diagnosis vs. foll...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Vécsei E,Steinwendner S,Kogler H,Innerhofer A,Hammer K,Haas OA,Amann G,Chott A,Vogelsang H,Schoenlechner R,Huf W,Vécsei A

    更新日期:2014-02-13 00:00:00

  • Long intestinal tube splinting prevents postoperative adhesive small-bowel obstruction in sclerosing encapsulating peritonitis.

    abstract:BACKGROUND:Sclerosing encapsulating peritonitis (SEP) is a rare cause of small-bowel obstruction. The optimal treatment for this condition remains controversial. METHODS:In this study, we performed a retrospective analysis of the data of 44 patients who underwent surgery for SEP between December 2001 and 2008 at our h...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Li M,Zhu W,Li Y,Jiang J,Li J,Li N

    更新日期:2014-11-25 00:00:00

  • A prospective comparison of short term results and functional recovery after laparoscopic subtotal colectomy and antiperistaltic cecorectal anastomosis with short colonic reservoir vs. long colonic reservoir.

    abstract:BACKGROUND:To observe and compare the short term results and functional recovery of laparoscopic subtotal colectomy with antiperistaltic cecorectal anastomosis (LSCACRA) in the treatment of Adult slow transit constipation (STC) with two different reservoir length: short colonic reservoir and long colonic reservoir. ME...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Wei D,Cai J,Yang Y,Zhao T,Zhang H,Zhang C,Zhang Y,Zhang J,Cai F

    更新日期:2015-03-18 00:00:00

  • Acute cholecystitis with massive upper gastrointestinal bleed: a case report and review of the literature.

    abstract:BACKGROUND:Cystic artery pseudoaneurysm is a rare complication following cholecystitis. Its presentation with upper gastrointestinal hemorrhage (UGIH) is even rarer. Thirteen patients with cystic artery pseudoaneurysm have been reported in the literature but only 2 of them presented with UGIH alone. CASE PRESENTATION:...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,评审


    authors: Saluja SS,Ray S,Gulati MS,Pal S,Sahni P,Chattopadhyay TK

    更新日期:2007-03-26 00:00:00

  • Vesicocutaneous fistula formation during treatment with sunitinib malate: Case report.

    abstract:BACKGROUND:The oral multi-kinase inhibitor sunitinib malate improves the survival of patients with gastrointestinal stromal tumors (GIST) after the disease progresses or intolerance to imatinib mesylate develops. Urinary fistulae arising during treatment with sunitinib for GIST have not been described. CASE PRESENTATI...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Watanabe K,Otsu S,Morinaga R,Kawano S,Hirashima Y,Sakashita H,Shirao K

    更新日期:2010-11-01 00:00:00

  • Comparison of sequential therapy and amoxicillin/tetracycline containing bismuth quadruple therapy for the first-line eradication of Helicobacter pylori: a prospective, multi-center, randomized clinical trial.

    abstract:BACKGROUND:The <80 % Helicobacter pylori eradication rate with sequential therapy is unsatisfactory. Modified bismuth quadruple therapy, replacing metronidazole with amoxicillin, could be promising because H. pylori resistance to tetracycline or to amoxicillin is relatively low. A 14-day modified bismuth quadruple prot...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Lee JY,Kim N,Park KS,Kim HJ,Park SM,Baik GH,Shim KN,Oh JH,Choi SC,Kim SE,Kim WH,Park SY,Kim GH,Lee BE,Jo Y,Hong SJ

    更新日期:2016-07-26 00:00:00

  • Faecal calprotectin level for assessing endoscopic activity and predicting future clinical course in patients with moderately active ulcerative colitis undergoing granulomonocytapheresis: a prospective cohort study.

    abstract:BACKGROUND:Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance of faecal calprotectin (FC) measurement during granulomonocytapheresis (GMA) for UC has not yet been ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Shimoyama T,Yamamoto T,Umegae S,Matsumoto K

    更新日期:2018-08-01 00:00:00

  • Implementation of population screening for colorectal cancer by repeated Fecal Immunochemical Test (FIT): third round.

    abstract:BACKGROUND:Colorectal cancer (CRC) is the most common cancer in Europe with a mortality rate of almost 50%. The prognosis of patients is largely determined by the clinical and pathological stage at the time of diagnosis. Population screening has been shown to reduce CRC-related mortality rate. Most screening programs w...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Stegeman I,de Wijkerslooth TR,Mallant-Hent RC,de Groot K,Stroobants AK,Fockens P,Mundt M,Bossuyt PM,Dekker E

    更新日期:2012-06-19 00:00:00

  • Changes of Treg and Th17 cells balance in the development of acute and chronic hepatitis B virus infection.

    abstract:BACKGROUND:Many studies suggest that in chronic hepatitis B virus (HBV) infection regulate T (Treg) cells and interlukin-17-producing T help cells (Th17) are mutually antagonistic in the immune response. This study is aimed to reveal the cell differentiation environment and the significance of Treg and Th17 balance in ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Xue-Song L,Cheng-Zhong L,Ying Z,Mo-Bin W

    更新日期:2012-05-01 00:00:00

  • Low bone mass in microscopic colitis.

    abstract:BACKGROUND:Microscopic colitis presents with similar symptoms to classic inflammatory bowel diseases. Osteoporosis is a common complication of Crohn's disease but there are no data concerning bone metabolism in microscopic colitis. AIMS:The aim of the present study was to evaluate bone density and metabolism in patien...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Lorinczy K,Lakatos G,Müllner K,Hritz I,Lakatos PL,Tulassay Z,Miheller P

    更新日期:2011-05-19 00:00:00

  • HFD and HFD-provoked hepatic hypoxia act as reciprocal causation for NAFLD via HIF-independent signaling.

    abstract:BACKGROUND:The occurrence of non-alcoholic fatty liver disease (NAFLD) is found to be higher in patients with obstructive sleep apnea (OSA), which is characterized by intermittent hypoxia. Activation of hypoxia-inducible factors has been shown in the development and progression of NAFLD, implying a cause and effects re...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Zhang X,Huang C,Li X,Shangguan Z,Wei W,Liu S,Yang S,Liu Y

    更新日期:2020-11-03 00:00:00

  • Drug interaction: omeprazole and phenprocoumon.

    abstract:BACKGROUND:Oral anticoagulants like the coumarin derivatives are characterised by a particularly narrow therapeutic range. Any interfering co-medication can pose a challenge to establishing a stable anticoagulant dosage regimen and thus present a serious risk for the patient. Here we describe two cases of patients on a...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Enderle C,Müller W,Grass U

    更新日期:2001-01-01 00:00:00

  • A survey of abnormalities in the colon and rectum in patients with haemorrhoids.

    abstract:BACKGROUND:Haemorrhoids are a common problem in daily practice. However, symptoms may also be caused by other abnormalities in the rectum or colon. Data on the presence of these abnormalities in patients with haemorrhoids is sparse. To examine the prevalence of abnormalities of the colon or rectum in patients with and ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Koning MV,Loffeld RJ

    更新日期:2010-07-07 00:00:00

  • Fluoroless intravascular ultrasound image-guided liver navigation in porcine models.

    abstract:BACKGROUND:An intravascular ultrasound catheter (IVUSc) was developed for intracardiac ultrasound to assess interventions with compelling results. However, intrahepatic vascular exploration was rarely tested and was always associated with X-ray techniques. The aim of this study was to demonstrate the feasibility to nav...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章


    authors: Urade T,Verde JM,García Vázquez A,Gunzert K,Pessaux P,Marescaux J,Giménez ME

    更新日期:2021-01-09 00:00:00