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Vegetarian diet, change in dietary patterns, and diabetes risk: a prospective study.

Abstract：

BACKGROUND/OBJECTIVES:Vegetarian diets are inversely associated with diabetes in Westerners but their impact on Asians-whose pathophysiology differ from Westerners-is unknown. We aim to investigate the association between a vegetarian diet, change in dietary patterns and diabetes risk in a Taiwanese Buddhist population. METHODS:We prospectively followed 2918 non-smoking, non-alcohol drinking Buddhists free of diabetes, cancer, and cardiovascular diseases at baseline, for a median of 5 years, with 183 incident diabetes cases confirmed. Diet was assessed through a validated food frequency questionnaire at baseline and a simple questionnaire during follow-ups. Incident cases of diabetes were ascertained through follow-up questionnaires, fasting glucose and HbA1C. Stratified Cox Proportional Hazards Regression was used to assess the effect of diets on risk of diabetes. RESULTS:Consistent vegetarian diet was associated with 35% lower hazards (HR: 0.65, 95% CI: 0.46, 0.92), while converting from a nonvegetarian to a vegetarian pattern was associated with 53% lower hazards (HR: 0.47, 95% CI: 0.30, 0.71) for diabetes, comparing with nonvegetarians while adjusting for age, gender, education, physical activity, family history of diabetes, follow-up methods, use of lipid-lowering medications, and baseline BMI. CONCLUSION:Vegetarian diet and converting to vegetarian diet may protect against diabetes independent of BMI among Taiwanese.

journal_name

Nutr Diabetes

journal_title

Nutrition & diabetes

authors

Chiu THT,Pan WH,Lin MN,Lin CL

doi

10.1038/s41387-018-0022-4

subject

Has Abstract

pub_date

2018-03-09 00:00:00

pages

12

issue

1

issn

2044-4052

pii

10.1038/s41387-018-0022-4

journal_volume

8

pub_type

杂志文章

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