An intricate case of multidrug resistant Plasmodium falciparum isolate imported from Cambodia.

abstract：BACKGROUND:Several anti-malarial drugs are associated with adverse cardiovascular effects. These effects may be exacerbated when different anti-malarials are used in combination. There has been no report yet on the potential cardiac effects of the combination artesunate-amodiaquine. METHODS:Electrocardiographic (ECG) ...

journal_title：Malaria journal

authors： Adjei GO,Oduro-Boatey C,Rodrigues OP,Hoegberg LC,Alifrangis M,Kurtzhals JA,Goka BQ

更新日期：2012-12-17 00:00:00

abstract：BACKGROUND:Anopheles arabiensis is a dominant vector of malaria in sub-Saharan Africa, which feeds indoors and outdoors on human and other vertebrate hosts, making it a difficult species to control with existing control methods. Novel methods that reduce human-vector interactions are, therefore, required to improve the...

journal_title：Malaria journal

authors： Jaleta KT,Hill SR,Birgersson G,Tekie H,Ignell R

更新日期：2016-07-21 00:00:00

abstract：BACKGROUND:Complex malaria infections are defined as those containing more than one genetically distinct lineage of Plasmodium parasite. Complexity of infection (COI) is a useful parameter to estimate from patient blood samples because it is associated with clinical outcome, epidemiology and disease transmission rate. ...

journal_title：Malaria journal

authors： Galinsky K,Valim C,Salmier A,de Thoisy B,Musset L,Legrand E,Faust A,Baniecki ML,Ndiaye D,Daniels RF,Hartl DL,Sabeti PC,Wirth DF,Volkman SK,Neafsey DE

更新日期：2015-01-19 00:00:00

abstract：BACKGROUND:The US FDA recently developed CD3+, a counterfeit detection tool that is based on sample illumination at specific wavelengths of light and visual comparison of suspect sample and packaging materials to an authentic sample. To test performance of the CD3+ in field conditions, a study was conducted in Ghana wh...

journal_title：Malaria journal

authors： Batson JS,Bempong DK,Lukulay PH,Ranieri N,Satzger RD,Verbois L

更新日期：2016-02-25 00:00:00

abstract：BACKGROUND:The use of anti-malarial drug combinations with artemisinin or with one of its derivatives is now widely recommended to overcome drug resistance in falciparum as well as vivax malaria. The fixed oral dose artemisinin-naphthoquine combination (ANQ, ARCO) is a newer artemisinin-based combination (ACT) therapy ...

journal_title：Malaria journal

authors： Hombhanje FW,Linge D,Saweri A,Kuanch C,Jones R,Toraso S,Geita J,Masta A,Kevau I,Hiawalyer G,Sapuri M

更新日期：2009-08-12 00:00:00

abstract：BACKGROUND:Malaria is a notifiable disease in the Netherlands, a non-endemic country. Imported malaria infections occur regularly among travellers, migrants and visitors. Surveillance data were analysed from 2008 to 2015. Trends in amounts of notifications among risk groups were analysed using Poisson regression. For a...

journal_title：Malaria journal

authors： de Gier B,Suryapranata FS,Croughs M,van Genderen PJ,Keuter M,Visser LG,van Vugt M,Sonder GJ

更新日期：2017-02-02 00:00:00

abstract：BACKGROUND:Automated detection of malaria and dengue infection has been actively researched for more than two decades. Although many improvements have been achieved, these solutions remain too expensive for most laboratories and clinics in developing countries. The low range HORIBA Medical Haematology Analyzer, Yumizen...

journal_title：Malaria journal

authors： Dharap P,Raimbault S

更新日期：2020-11-23 00:00:00

abstract：:Natural compounds, mostly from plants, have been the mainstay of traditional medicine for thousands of years. They have also been the source of lead compounds for modern medicine, but the extent of mining of natural compounds for such leads decreased during the second half of the 20th century. The advantage of natural...

journal_title：Malaria journal

authors： Ginsburg H,Deharo E

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:Prompt and effective malaria diagnosis not only alleviates individual suffering, but also decreases malaria transmission at the community level. The commonly used diagnostic methods, microscopy and rapid diagnostic tests, are usually insensitive at very low-density parasitaemia. Molecular techniques, on the ...

journal_title：Malaria journal

authors： Golassa L,Enweji N,Erko B,Aseffa A,Swedberg G

更新日期：2013-10-03 00:00:00

abstract：BACKGROUND:Antibody immunity is thought to be essential to prevent severe Plasmodium falciparum infection, but the exact correlates of protection are unknown. Over time, children in endemic areas acquire non-sterile immunity to malaria that correlates with development of antibodies to merozoite invasion proteins and pa...

journal_title：Malaria journal

authors： Kessler A,Campo JJ,Harawa V,Mandala WL,Rogerson SJ,Mowrey WB,Seydel KB,Kim K

更新日期：2018-04-25 00:00:00

abstract：BACKGROUND:The susceptibility of anopheline mosquito species to Plasmodium infection is known to be variable with some mosquitoes more permissive to infection than others. Little work, however, has been carried out investigating the susceptibility of major malaria vectors to geographically diverse tropical isolates of ...

journal_title：Malaria journal

authors： Hume JC,Tunnicliff M,Ranford-Cartwright LC,Day KP

更新日期：2007-10-24 00:00:00

abstract：:The fight against malaria is increasingly threatened by failures in vector control due to growing insecticide resistance. This review examines the recent primary research that addresses the putative relationship between agricultural insecticide use and trends in insecticide resistance. To do so, descriptive evidence o...

journal_title：Malaria journal

authors： Reid MC,McKenzie FE

更新日期：2016-02-19 00:00:00

abstract：BACKGROUND:As a result of the reintroduction of malaria in the Republic of Korea (ROK) in 1993 and the threat to military and civilian populations, the Korea Military National Defense (MND) increased emphasis on vector control in 2012 at ROK Army (ROKA) installations located near the DMZ, while decreasing chemoprophyla...

journal_title：Malaria journal

authors： Chang KS,Yoo DH,Ju YR,Lee WG,Roh JY,Kim HC,Klein TA,Shin EH

更新日期：2016-05-05 00:00:00

abstract：BACKGROUND:In Uganda, over half of under-five child mortality is attributed to three infectious diseases: malaria, pneumonia and diarrhoea. Integrated community case management (iCCM) trains village health workers (VHWs) to provide in-home diagnosis and treatment of these common childhood illnesses. For severely ill ch...

journal_title：Malaria journal

authors： English L,Miller JS,Mbusa R,Matte M,Kenney J,Bwambale S,Ntaro M,Patel P,Mulogo E,Stone GS

更新日期：2016-04-29 00:00:00

abstract：BACKGROUND:Genetically-modified (GM) mosquitoes have been proposed as part of an integrated vector control strategy for malaria control. Public acceptance is essential prior to field trials, particularly since mosquitoes are a vector of human disease and genetically modified organisms (GMOs) face strong scepticism in d...

journal_title：Malaria journal

authors： Marshall JM,Touré MB,Traore MM,Famenini S,Taylor CE

更新日期：2010-05-14 00:00:00

abstract：:The potential use of ivermectin as an additional vector control tool is receiving increased attention from the malaria elimination community, driven by the increased importance of outdoor/residual malaria transmission and the threat of insecticide resistance where vector tools have been scaled-up. This report summariz...

journal_title：Malaria journal

authors： Chaccour CJ,Rabinovich NR,Slater H,Canavati SE,Bousema T,Lacerda M,Ter Kuile F,Drakeley C,Bassat Q,Foy BD,Kobylinski K

更新日期：2015-06-11 00:00:00

abstract：BACKGROUND:The sulphadoxine/pyrimethamine (SDX/PYR) combination had been chosen to treat uncomplicated falciparum malaria in Malaysia for more than 30 years. Non-silent mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes are responsible for the resistance to pyrimethamine and sulphadox...

journal_title：Malaria journal

authors： Lau TY,Sylvi M,William T

更新日期：2013-12-10 00:00:00

abstract：BACKGROUND:Resistance to multiple classes of insecticides has been detected in the malaria vector Anopheles albimanus in northwest Peru. Acetylcholinesterase (AChE) insensitivity has previously been associated with resistance to organophosphate (OP) and carbamate (CA) insecticides in arthropods. A single point mutation...

journal_title：Malaria journal

authors： Liebman KA,Pinto J,Valle J,Palomino M,Vizcaino L,Brogdon W,Lenhart A

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all five Plasmodium parasites causing disease in humans. Although not included in the World Health Organization criteria for severe Plasmodium falciparum malaria, severe thrombocytopaenia has been increasingly men...

journal_title：Malaria journal

authors： Antinori S,Corona A,Ridolfo AL,Galimberti L,Ricaboni D,Milazzo L,Corbellino M

更新日期：2016-02-19 00:00:00

abstract：BACKGROUND:In areas with ongoing malaria transmission, strategies to clear parasites from populations can reduce infection and transmission. The objective of this paper was to describe a malaria mass testing and treatment (MTAT) intervention implemented in six kebeles (villages) in Amhara Region, Ethiopia, at the begin...

journal_title：Malaria journal

authors： Scott CA,Yeshiwondim AK,Serda B,Guinovart C,Tesfay BH,Agmas A,Zeleke MT,Guesses GS,Ayenew AL,Workie WM,Steketee RW,Earle D,Bezabih B,Getachew A

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:There is growing concern that malaria vector resistance to pyrethroid insecticides may reduce the effectiveness of long-lasting insecticidal nets (LLINs). Combination LLINs are designed to control susceptible and pyrethroid-resistant mosquito populations through a mixture of pyrethroid with piperonyl butoxid...

journal_title：Malaria journal

authors： Cisse MBM,Sangare D,Oxborough RM,Dicko A,Dengela D,Sadou A,Mihigo J,George K,Norris L,Fornadel C

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:In the last decade, several epidemiological studies have demonstrated the potential of using seroprevalence (SP) and seroconversion rate (SCR) as informative indicators of malaria burden in low transmission settings or in populations on the cusp of elimination. However, most of studies are designed to contro...

journal_title：Malaria journal

authors： Sepúlveda N,Drakeley C

更新日期：2015-04-03 00:00:00

abstract：BACKGROUND:Agro-ecological systems have been associated with increased malaria intensity. This study determined association between different agro-ecological systems, prevalence of malaria parasitaemia and anaemia in Mvomero district, Tanzania. METHODS:The study was carried out in three agro-ecosystems namely, savanna...

journal_title：Malaria journal

authors： Rumisha SF,Shayo EH,Mboera LEG

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentation. METHODS:Retrospective analysis of data collected through the Manhiça morbidity surveillance sy...

journal_title：Malaria journal

authors： Guinovart C,Bassat Q,Sigaúque B,Aide P,Sacarlal J,Nhampossa T,Bardají A,Nhacolo A,Macete E,Mandomando I,Aponte JJ,Menéndez C,Alonso PL

更新日期：2008-02-26 00:00:00

abstract：BACKGROUND:Malaria is a major cause of morbidity and mortality worldwide with over one million deaths annually, particularly in children under five years. This study was the first to examine plasma cytokines, chemokines and cellular immune responses in pre-school Nigerian children infected with Plasmodium falciparum fr...

journal_title：Malaria journal

authors： Noone C,Parkinson M,Dowling DJ,Aldridge A,Kirwan P,Molloy SF,Asaolu SO,Holland C,O'Neill SM

更新日期：2013-01-07 00:00:00

abstract：:Malaria is a public health problem in French Guiana. Plasmodium vivax is the most frequent parasite. The objective of this analysis was to estimate the proportion of relapses in the burden of vivax malaria using the statistical rule stating that any case of vivax malaria occurring less than 90 days following a first e...

journal_title：Malaria journal

authors： Nacher M,Stefani A,Basurko C,Lemonnier D,Djossou F,Demar M,Elenga N,Brousse P,Ville M,Carme B

更新日期：2013-10-24 00:00:00

abstract：BACKGROUND:The potential emergence and spread of resistance to artemisinins in the Plasmodium falciparum malaria parasite constitutes a major global health threat. Hence, improving the efficacy of artemisinins and of artemisinin-based combination therapy (ACT) represents a major short-term goal in the global fight agai...

journal_title：Malaria journal

authors： Moradin N,Torre S,Gauthier S,Tam M,Hawari J,Vandercruyssen K,De Spiegeleer B,Fortin A,Stevenson MM,Gros P

更新日期：2016-05-06 00:00:00

abstract：BACKGROUND:Real-time PCR is a sensitive and specific method for the analysis of Plasmodium DNA. However, prior purification of genomic DNA from blood is necessary since PCR inhibitors and quenching of fluorophores from blood prevent efficient amplification and detection of PCR products. METHODS:Reagents designed to sp...

journal_title：Malaria journal

authors： Taylor BJ,Martin KA,Arango E,Agudelo OM,Maestre A,Yanow SK

更新日期：2011-08-19 00:00:00

abstract：BACKGROUND:Knowledge of the ecological differences between the molecular forms of Anopheles gambiae and their sibling species, An. arabiensis might lead to understanding their unique contribution to disease transmission and to better vector control as well as to understanding the evolutionary forces that have separated...

journal_title：Malaria journal

authors： Yaro AS,Dao A,Adamou A,Crawford JE,Ribeiro JM,Gwadz R,Traoré SF,Lehmann T

更新日期：2006-03-22 00:00:00

abstract：BACKGROUND:Whole-parasite immunization remains the benchmark in malaria vaccine development. A major bottleneck in the translation of whole-parasite immunization towards routine vaccination is the mode of administration, since high degrees of protection are currently only achieved by intravenous, and not by intradermal...

journal_title：Malaria journal

authors： Pfeil J,Heine JF,Mueller AK

更新日期：2015-01-28 00:00:00