Abstract:
:Stress hyperglycaemia is a common event in acute critical illness. There is increasing evidence that maintaining normoglycaemia and treatment with insulin (or with glucose-insulin-potassium [GIK]), even in non-diabetic persons, is helpful in limiting organ damage after myocardial infarction, stroke, traumatic brain injury and other conditions, even though the conditions may be accompanied by insulin resistance. A landmark study now suggests that maintaining normoglycaemia with intensive insulin treatment in a heterogeneous population of critically ill patients decreases morbidity and mortality. The potential mechanisms that underlie such a beneficial effect are discussed.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Johan Groeneveld AB,Beishuizen A,Visser FCdoi
10.1186/cc1463keywords:
subject
Has Abstractpub_date
2002-04-01 00:00:00pages
102-5issue
2eissn
1364-8535issn
1466-609Xjournal_volume
6pub_type
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