Insulin: a wonder drug in the critically ill?

Abstract:

:Stress hyperglycaemia is a common event in acute critical illness. There is increasing evidence that maintaining normoglycaemia and treatment with insulin (or with glucose-insulin-potassium [GIK]), even in non-diabetic persons, is helpful in limiting organ damage after myocardial infarction, stroke, traumatic brain injury and other conditions, even though the conditions may be accompanied by insulin resistance. A landmark study now suggests that maintaining normoglycaemia with intensive insulin treatment in a heterogeneous population of critically ill patients decreases morbidity and mortality. The potential mechanisms that underlie such a beneficial effect are discussed.

journal_name

Crit Care

authors

Johan Groeneveld AB,Beishuizen A,Visser FC

doi

10.1186/cc1463

keywords:

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

102-5

issue

2

eissn

1364-8535

issn

1466-609X

journal_volume

6

pub_type

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