Exposure to low dose computed tomography for lung cancer screening and risk of cancer: secondary analysis of trial data and risk-benefit analysis.

abstract：OBJECTIVE:To assess the effectiveness of health checks by nurses in reducing risk factors for cardiovascular disease in patients from general practice. DESIGN:Randomised controlled trial. SETTING:Five urban general practices in Bedfordshire. SUBJECTS:2136 patients receiving an initial health check in 1989-91 and sch...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1994-01-29 00:00:00

abstract：OBJECTIVES:To investigate the association between intake of fish and n-3 polyunsaturated fatty acids (n-3 PUFA) and the risk of breast cancer and to evaluate the potential dose-response relation. DESIGN:Meta-analysis and systematic review of prospective cohort studies. DATA SOURCES:PubMed and Embase up to December 20...

journal_title：BMJ (Clinical research ed.)

authors： Zheng JS,Hu XJ,Zhao YM,Yang J,Li D

更新日期：2013-06-27 00:00:00

abstract：:This paper summarizes the key findings of a U.S. study of 48 primary care physicians acting as gatekeepers in a large health maintenance organization to determine the effects of their cost containment role on the doctor patient relationship. Taylor highlights some of the findings and conclusions that he believes are ...

journal_title：BMJ (Clinical research ed.)

authors： Taylor TR

更新日期：1989-11-25 00:00:00

abstract：OBJECTIVE:To examine whether the decline in child injury death rates between 1981 and 1991 varied by social class. DESIGN:Comparison of class specific child injury death rates for 1979, 1980, 1982, and 1983, with those for the four years 1989-92. SETTING:England and Wales. SUBJECTS:Children aged 0-15 years. MAIN OU...

journal_title：BMJ (Clinical research ed.)

authors： Roberts I,Power C

更新日期：1996-09-28 00:00:00

abstract：:Recent changes in the Russian government introduced by Boris Yeltsin include the appointment of Eduard Nechaev as health minister at the beginning of this year. The appointment received little publicity in the West, although his predecessor was sacked after only one year for failing to make any effort to improve healt...

journal_title：BMJ (Clinical research ed.)

authors： Ryan M

更新日期：1993-04-03 00:00:00

abstract：OBJECTIVES:To compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a healthy child. DESIGN:Multicentre, open label, three arm, parallel group, ran...

journal_title：BMJ (Clinical research ed.)

authors： Bensdorp AJ,Tjon-Kon-Fat RI,Bossuyt PM,Koks CA,Oosterhuis GJ,Hoek A,Hompes PG,Broekmans FJ,Verhoeve HR,de Bruin JP,van Golde R,Repping S,Cohlen BJ,Lambers MD,van Bommel PF,Slappendel E,Perquin D,Smeenk JM,Pelinck MJ,

更新日期：2015-01-09 00:00:00

abstract：:In the absence of any systematic evaluation of the changes it has made to the NHS, the government cites three "indicators of success." These are record numbers of patients treated, shorter waiting times for hospital treatment, and more children being immunised against the main childhood diseases. Closer inspection of ...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1995-04-22 00:00:00

abstract：:Currently, clinicians have to make decisions about how to manage pulmonary embolism on the basis of imperfect tests and assessment of odds. Management protocols that inevitably result in large numbers of patients being referred for angiography are unhelpful. Management decisions based on assessment of odds and investi...

journal_title：BMJ (Clinical research ed.)

authors： Fennerty T

更新日期：1997-02-08 00:00:00

abstract：OBJECTIVE:To compare the use and effect of a computer based information system for cancer patients that is personalised using each patient's medical record with a system providing only general information and with information provided in booklets. DESIGN:Randomised trial with three groups. Data collected at start of r...

journal_title：BMJ (Clinical research ed.)

authors： Jones R,Pearson J,McGregor S,Cawsey AJ,Barrett A,Craig N,Atkinson JM,Gilmour WH,McEwen J

更新日期：1999-11-06 00:00:00

abstract：OBJECTIVE:To assess the associations between different antidepressant treatments and the rates of suicide and attempted suicide or self harm in people with depression. DESIGN:Cohort study. SETTING:Patients registered with UK general practices contributing data to the QResearch database. PARTICIPANTS:238,963 patients...

journal_title：BMJ (Clinical research ed.)

authors： Coupland C,Hill T,Morriss R,Arthur A,Moore M,Hippisley-Cox J

更新日期：2015-02-18 00:00:00

abstract：OBJECTIVE:To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history. DESIGN:Prospective register linkage study. SUBJECTS:All women with a reproductive outcome (live birth, stillbirth, spontaneous abortion ...

journal_title：BMJ (Clinical research ed.)

authors： Nybo Andersen AM,Wohlfahrt J,Christens P,Olsen J,Melbye M

更新日期：2000-06-24 00:00:00

abstract：OBJECTIVE:To determine how length of anticoagulation and clinical presentation of venous thromboembolism influence the risk of recurrence after anticoagulant treatment is stopped and to identify the shortest length of anticoagulation that reduces the risk of recurrence to its lowest level. DESIGN:Pooled analysis of in...

journal_title：BMJ (Clinical research ed.)

authors： Boutitie F,Pinede L,Schulman S,Agnelli G,Raskob G,Julian J,Hirsh J,Kearon C

更新日期：2011-05-24 00:00:00

abstract：OBJECTIVES:To identify and calculate the prevalence of spin in studies of spin. DESIGN:Meta-research analysis (research on research). SETTING:35 studies of spin in the scientific literature. MAIN OUTCOME MEASURES:Spin, categorised as: reporting practices that distort the presentation and interpretation of results, c...

journal_title：BMJ (Clinical research ed.)

authors： Bero L,Chiu K,Grundy Q

更新日期：2019-12-18 00:00:00

abstract：STUDY QUESTION:What are the long term trends in the total (live births, fetal deaths, and terminations of pregnancy for fetal anomaly) and live birth prevalence of neural tube defects (NTD) in Europe, where many countries have issued recommendations for folic acid supplementation but a policy for mandatory folic acid f...

journal_title：BMJ (Clinical research ed.)

authors： Khoshnood B,Loane M,de Walle H,Arriola L,Addor MC,Barisic I,Beres J,Bianchi F,Dias C,Draper E,Garne E,Gatt M,Haeusler M,Klungsoyr K,Latos-Bielenska A,Lynch C,McDonnell B,Nelen V,Neville AJ,O'Mahony MT,Queisser-Luf

更新日期：2015-11-24 00:00:00

abstract：:London's health care problems, particularly underfunding, are mirrored in other major cities in the United Kingdom and abroad. None has found the perfect solution, but the debates on the Tomlinson report provide an opportunity to review how to manage the three major areas of service provision, medical education, and r...

journal_title：BMJ (Clinical research ed.)

authors： Maxwell R

更新日期：1993-01-16 00:00:00

abstract：OBJECTIVE:To investigate the risks of adverse pregnancy and birth outcomes for treated and untreated bipolar disorder during pregnancy. DESIGN:Population based cohort study using data from national health registers. SETTING:Sweden. PARTICIPANTS:332,137 women with a last menstrual period anytime after 1 July 2005 and...

journal_title：BMJ (Clinical research ed.)

authors： Bodén R,Lundgren M,Brandt L,Reutfors J,Andersen M,Kieler H

更新日期：2012-11-08 00:00:00

abstract：OBJECTIVES:To assess the association of Apgar score 5 minutes after birth with cerebral palsy in both normal weight and low birthweight children, and also the association with the cerebral palsy subdiagnoses of quadriplegia, diplegia, and hemiplegia. DESIGN:Population based cohort study. SETTING:The Medical Birth Reg...

journal_title：BMJ (Clinical research ed.)

authors： Lie KK,Grøholt EK,Eskild A

更新日期：2010-10-06 00:00:00

abstract：OBJECTIVE:To examine the patterns of physical activity among British schoolchildren aged 11 to 16 and to assess whether the children experience the intensity and duration of physical activity that are believed to stress the cardiopulmonary system appropriately. DESIGN:Cross sectional study of a sample of children draw...

journal_title：BMJ (Clinical research ed.)

authors： Armstrong N,Balding J,Gentle P,Kirby B

更新日期：1990-07-28 00:00:00

abstract：OBJECTIVES:To examine the association between income inequality and the risk of mortality and readmission within 30 days of hospitalization. DESIGN:Retrospective cohort study of Medicare beneficiaries in the United States. Hierarchical, logistic regression models were developed to estimate the association between inco...

journal_title：BMJ (Clinical research ed.)

authors： Lindenauer PK,Lagu T,Rothberg MB,Avrunin J,Pekow PS,Wang Y,Krumholz HM

更新日期：2013-02-14 00:00:00

abstract：OBJECTIVES:To assess the feasibility and effectiveness of a general practice based, proactive system of asthma care in children. DESIGN:Randomised controlled trial with cluster sampling by general practice. SETTING:General practices in the northern region of the Australian Capital Territory. PARTICIPANTS:174 childre...

journal_title：BMJ (Clinical research ed.)

authors： Glasgow NJ,Ponsonby AL,Yates R,Beilby J,Dugdale P

更新日期：2003-09-20 00:00:00

abstract：OBJECTIVE: To determine whether the treatment effect of apixaban versus warfarin differs with increasing numbers of concomitant drugs used by patients with atrial fibrillation. DESIGN: Post hoc analysis performed in 2015 of results from ARISTOTLE (apixaban for reduction in stroke and other thromboembolic events in atr...

journal_title：BMJ (Clinical research ed.)

authors： Jaspers Focks J,Brouwer MA,Wojdyla DM,Thomas L,Lopes RD,Washam JB,Lanas F,Xavier D,Husted S,Wallentin L,Alexander JH,Granger CB,Verheugt FW

更新日期：2016-06-15 00:00:00

abstract：OBJECTIVES:To examine the individual and combined associations of unhealthy behaviours (low/intermediate physical activity, consuming fruit and vegetables less than once a day, current smoking/short term ex-smoking, never/former/heavy alcohol drinking), assessed at start of follow-up, with hazard of disability among ol...

journal_title：BMJ (Clinical research ed.)

authors： Artaud F,Dugravot A,Sabia S,Singh-Manoux A,Tzourio C,Elbaz A

更新日期：2013-07-23 00:00:00

abstract：OBJECTIVE:To describe the association between epithelial cell IgM, which has previously been associated with an increased incidence of loss of renal graft in children, with a novel cutaneous eruption and unexplained native renal disease. DESIGN:Observational study on children with epithelial cell antibody presenting w...

journal_title：BMJ (Clinical research ed.)

authors： Deal JE,Groves RW,Harmer AW,Welsh KI,MacDonald DM,Rigden SP

更新日期：1991-07-20 00:00:00

abstract：OBJECTIVE:To compare ultrasonography with intravenous urography in the investigation of adults with haematuria. DESIGN:Prospective study entailing the examination of all patients with both investigations concurrently. The investigations were performed independently on routine lists by different duty radiologists. Each...

journal_title：BMJ (Clinical research ed.)

authors： Spencer J,Lindsell D,Mastorakou I

更新日期：1990-11-10 00:00:00

abstract：PROBLEM:Zimbabwe has one of the highest rates of HIV seroprevalence in the world. In 2001 only 4% of women and children in need of services for prevention of mother to child transmission of HIV were receiving them. DESIGN:Pilot implementation of the first programme for prevention of mother to child transmission of HIV...

journal_title：BMJ (Clinical research ed.)

authors： Perez F,Orne-Gliemann J,Mukotekwa T,Miller A,Glenshaw M,Mahomva A,Dabis F

更新日期：2004-11-13 00:00:00

abstract：OBJECTIVE:To compare direct and indirect costs of day and inpatient treatment of acute psychiatric illness. DESIGN:Randomised controlled trial with outcome and costs assessed over 12 months after the date of admission. SETTING:Teaching hospital in an inner city area. SUBJECTS:179 patients with acute psychiatric illn...

journal_title：BMJ (Clinical research ed.)

authors： Creed F,Mbaya P,Lancashire S,Tomenson B,Williams B,Holme S

更新日期：1997-05-10 00:00:00

abstract：OBJECTIVE:To assess the feasibility and acceptability of screening young children for iron deficiency in a deprived inner city practice and to assess the effects of a programme of dietary education. DESIGN:Prospective study of children in general practice, comparison with historical controls. SETTING:A deprived inner...

journal_title：BMJ (Clinical research ed.)

authors： James J,Lawson P,Male P,Oakhill A

更新日期：1989-09-30 00:00:00

abstract：:The World Health Organization's (WHO) definition of health as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity" had the merit of widening concepts of health to include psychological and social aspects, but is of no practical use. In fact, this statement m...

journal_title：BMJ (Clinical research ed.)

authors： Saracci R

更新日期：1997-05-10 00:00:00

abstract：OBJECTIVE:To quantify and compare the contribution of 306 diseases and injuries to the changes in health adjusted life expectancy at birth (HALE0) between 1990 and 2013. DESIGN:Retrospective demographic analysis based on aggregated data and using life table technique, Sullivan method, and decomposition method for diff...

journal_title：BMJ (Clinical research ed.)

authors： Chen H,Chen G,Zheng X,Guo Y

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVE:To identify the attitudes of general practitioners towards the use of thermometers in general practice. DESIGN:Postal questionnaire survey. SETTING:All general practitioners in the catchment area of Frimley Park Hospital, Surrey. SUBJECTS:145 general practitioners. MAIN OUTCOME MEASURES:Answers to questio...

journal_title：BMJ (Clinical research ed.)

authors： Clarke S

更新日期：1992-04-11 00:00:00