Health consequences of shift work and insufficient sleep.

abstract：OBJECTIVE:To derive and validate an algorithm to estimate the absolute risk of having ovarian cancer in women with and without symptoms. DESIGN:Cohort study with data from 375 UK QResearch general practices for development and 189 for validation. PARTICIPANTS:Women aged 30-84 without a diagnosis of ovarian cancer at ...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Coupland C

更新日期：2011-01-04 00:00:00

abstract：:WHO is under pressure from all sides to justify its existence. Donors want to know what they are getting for their money, and health professionals question the relevance of the organisation's work. The pressure to justify itself is perhaps strongest of all in Europe, where most member countries have fully fledged heal...

journal_title：BMJ (Clinical research ed.)

authors： Godlee F

更新日期：1995-02-11 00:00:00

abstract：OBJECTIVES:To investigate the perspectives of patients with asthma on the use of an action plan and the implementation of this plan during an asthma attack that culminated in a visit to an emergency department. DESIGN:Qualitative study. SETTING:Tertiary teaching hospital, suburban hospital, and rural hospital. PARTI...

journal_title：BMJ (Clinical research ed.)

authors： Douglass J,Aroni R,Goeman D,Stewart K,Sawyer S,Thien F,Abramson M

更新日期：2002-04-27 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of different screening strategies for abdominal aortic aneurysm in men, from the perspective of a national health service. SETTING:Screening units at regional hospitals. PARTICIPANTS:Hypothetical cohort of 65 year old men from the general population. MAIN OUTCOME MEASURES:C...

journal_title：BMJ (Clinical research ed.)

authors： Søgaard R,Laustsen J,Lindholt JS

更新日期：2012-07-05 00:00:00

abstract：OBJECTIVE:To assess the efficacy of arthroscopic subacromial decompression (ASD) by comparing it with diagnostic arthroscopy, a placebo surgical intervention, and with a non-operative alternative, exercise therapy, in a more pragmatic setting. DESIGN:Multicentre, three group, randomised, double blind, sham controlled ...

journal_title：BMJ (Clinical research ed.)

authors： Paavola M,Malmivaara A,Taimela S,Kanto K,Inkinen J,Kalske J,Sinisaari I,Savolainen V,Ranstam J,Järvinen TLN,Finnish Subacromial Impingement Arthroscopy Controlled Trial (FIMPACT) Investigators.

更新日期：2018-07-19 00:00:00

abstract：OBJECTIVE:To examine whether there are too many hospital beds in London. DESIGN:Analysis of data from the Hospital In-Patient Enquiry, Mental Health Enquiry, health service indicators, and Emergency Bed Service. SETTING:England, London, and inner London. RESULTS:Hospital admission rates for acute plus geriatric serv...

journal_title：BMJ (Clinical research ed.)

authors： Jarman B

更新日期：1993-04-10 00:00:00

abstract：:One hundred and two patients returned structured questionnaires sent to clinics for sickle cell disease in the United Kingdom in order to gain greater insight into the patients' perception of painful crises. Most patients who suffer pain crises experience a prodromal stage that should be investigated further to find o...

journal_title：BMJ (Clinical research ed.)

authors： Murray N,May A

更新日期：1988-08-13 00:00:00

abstract：:The treatment of renal cell carcinoma (RCC) has changed greatly over the past 15 years. Progress in the surgical management of the primary tumor and increased understanding of the molecular biology and genomics of the disease have led to the development of new therapeutic agents. The management of the primary tumor ha...

journal_title：BMJ (Clinical research ed.)

authors： Jonasch E,Gao J,Rathmell WK

更新日期：2014-11-10 00:00:00

abstract：OBJECTIVE:To estimate the comparative clinical efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults. DESIGN:Systematic review with pairwise and network meta-analysis. DATA SOURCES:Electronic search of Embase, PubMed/Medline, and PsycINFO up to 8 M...

journal_title：BMJ (Clinical research ed.)

authors： Mutz J,Vipulananthan V,Carter B,Hurlemann R,Fu CHY,Young AH

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVES:To determine the accuracy of diagnoses of schizophrenia and non-affective psychosis entered by general practitioners on a computer system. To compare recording of clinical events on computer with written records. DESIGN:Examination of case notes of all patients with a computer diagnosis of psychosis. Search...

journal_title：BMJ (Clinical research ed.)

authors： Nazareth I,King M,Haines A,Rangel L,Myers S

更新日期：1993-07-03 00:00:00

abstract：:The instrument through which a commissioner purchases health services from a provider is, as in other walks of life, a contract, so considerable importance has been attached by the NHS Executive to the contracting mechanism. A contract should in theory influence the quality of the service provided, but they are in man...

journal_title：BMJ (Clinical research ed.)

authors： Hopkins A,Solomon JK

更新日期：1996-08-24 00:00:00

abstract：OBJECTIVE:To assess whether a late evening meal would improve nitrogen balance in patients with cirrhosis of the liver. DESIGN:Randomised crossover study of meal schedules comparing three meals a day with four or six meals a day, the four and six meal schedules both including a late evening meal (2300). SETTING:Metab...

journal_title：BMJ (Clinical research ed.)

authors： Swart GR,Zillikens MC,van Vuure JK,van den Berg JW

更新日期：1989-11-11 00:00:00

abstract：OBJECTIVE:To determine the appropriateness of referrals from general practice to hospital outpatient departments. DESIGN:Prospective audit of referrals from a group practice over one year. SETTING:Six handed practice in a southern coastal town. SUBJECTS:All patients referred during the study period for whom a copy o...

journal_title：BMJ (Clinical research ed.)

authors： Emmanuel J,Walter N

更新日期：1989-09-16 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of parenteral corticosteroids for the relief of acute severe migraine headache and prevention of recurrent headaches. DESIGN:Meta-analysis. DATA SOURCES:Electronic databases (Cochrane Central Register of Controlled Trials, Medline, Embase, LILACS, and CINAHL), conference proceed...

journal_title：BMJ (Clinical research ed.)

authors： Colman I,Friedman BW,Brown MD,Innes GD,Grafstein E,Roberts TE,Rowe BH

更新日期：2008-06-14 00:00:00

abstract：:A total of 563 white primigravid patients at Raigmore Hospital, Inverness, were recruited in a prospective study to examine the association between maternal height, shoe size, and the outcome of labour. There was a significantly increased caesarean section rate in women of short stature but no association between mode...

journal_title：BMJ (Clinical research ed.)

authors： Mahmood TA,Campbell DM,Wilson AW

更新日期：1988-08-20 00:00:00

abstract：OBJECTIVE: To measure the association between a surgeon's degree of specialization in a specific procedure and patient mortality. DESIGN: Retrospective analysis of Medicare data. SETTING: US patients aged 66 or older enrolled in traditional fee for service Medicare. PARTICIPANTS: 25 152 US surgeons who performed one...

journal_title：BMJ (Clinical research ed.)

authors： Sahni NR,Dalton M,Cutler DM,Birkmeyer JD,Chandra A

更新日期：2016-07-21 00:00:00

abstract：OBJECTIVE:To assess long term survival (> 5 years) and quality of life in severely ill patients referred for urgent cardiac transplantation. SETTING:Tertiary referral centres: before transplantation at the National Heart Hospital (late 1984 to end 1986); after transplantation at Harefield Hospital. SUBJECTS:Eighteen ...

journal_title：BMJ (Clinical research ed.)

authors： Mulcahy D,Fitzgerald M,Wright C,Sparrow J,Pepper J,Yacoub M,Fox KM

更新日期：1993-01-09 00:00:00

abstract：OBJECTIVE:To assess predictors of mortality in a population of people prescribed methadone. DESIGN:Retrospective cohort study. SETTING:Geographically defined population in Tayside, Scotland. PARTICIPANTS:2378 people prescribed and dispensed liquid methadone between January 1993 and February 2004. MAIN OUTCOME MEASU...

journal_title：BMJ (Clinical research ed.)

authors： McCowan C,Kidd B,Fahey T

更新日期：2009-06-16 00:00:00

abstract：:Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients' health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy, there are barriers to access for these t...

journal_title：BMJ (Clinical research ed.)

authors： Kay-Stacey M,Attarian H

更新日期：2016-07-06 00:00:00

abstract：OBJECTIVES:To assess and improve the quality of care provided to women undergoing induced abortion. DESIGN:Two rounds of prospective, criterion based case note review audit. SETTING:Ten NHS gynaecology units throughout Scotland. SUBJECTS:2004 patient episodes of abortion care identified consecutively during two roun...

journal_title：BMJ (Clinical research ed.)

authors： Penney GC,Glasier A,Templeton A

更新日期：1994-07-02 00:00:00

abstract：OBJECTIVES:To identify and calculate the prevalence of spin in studies of spin. DESIGN:Meta-research analysis (research on research). SETTING:35 studies of spin in the scientific literature. MAIN OUTCOME MEASURES:Spin, categorised as: reporting practices that distort the presentation and interpretation of results, c...

journal_title：BMJ (Clinical research ed.)

authors： Bero L,Chiu K,Grundy Q

更新日期：2019-12-18 00:00:00

abstract：OBJECTIVE:To determine whether being overweight in childhood increases adult obesity and risk of disease. DESIGN:Prospective cohort study. SETTING:City of Newcastle upon Tyne. PARTICIPANTS:932 members of thousand families 1947 birth cohort, of whom 412 attended for clinical examination age 50. MAIN OUTCOME MEASURES...

journal_title：BMJ (Clinical research ed.)

authors： Wright CM,Parker L,Lamont D,Craft AW

更新日期：2001-12-01 00:00:00

abstract：:All developmental screening in Somerset is performed by general practitioners and health visitors. A retrospective review of a cohort of 1504 7 year old children living in semirural Somerset found that the development assessment by a health visitor at age 3 1/2 years had a sensitivity of 45% for identifying the 103 ch...

journal_title：BMJ (Clinical research ed.)

authors： Dearlove J,Kearney D

更新日期：1990-05-05 00:00:00

abstract：OBJECTIVE:To characterise the functional morphology of the nasal microcirculation in humans in comparison with reindeer as a means of testing the hypothesis that the luminous red nose of Rudolph, one of the most well known reindeer pulling Santa Claus's sleigh, is due to the presence of a highly dense and rich nasal mi...

journal_title：BMJ (Clinical research ed.)

authors： Ince C,van Kuijen AM,Milstein DM,Yürük K,Folkow LP,Fokkens WJ,Blix AS

更新日期：2012-12-14 00:00:00

abstract：OBJECTIVE:To determine whether rates of suicide changed in Toronto after a barrier was erected at Bloor Street Viaduct, the bridge with the world's second highest annual rate of suicide by jumping after Golden Gate Bridge in San Francisco. DESIGN:Natural experiment. SETTING:City of Toronto and province of Ontario, Ca...

journal_title：BMJ (Clinical research ed.)

authors： Sinyor M,Levitt AJ

更新日期：2010-07-06 00:00:00

abstract：:Physical examination of the cardiovascular system is central to contemporary teaching and practice in clinical medicine. Evidence about its value focuses on its diagnostic accuracy and varies widely in methodological quality and statistical power. This makes collation, analysis, and understanding of results difficult ...

journal_title：BMJ (Clinical research ed.)

authors： Elder A,Japp A,Verghese A

更新日期：2016-07-27 00:00:00

abstract：OBJECTIVE: To determine whether the treatment effect of apixaban versus warfarin differs with increasing numbers of concomitant drugs used by patients with atrial fibrillation. DESIGN: Post hoc analysis performed in 2015 of results from ARISTOTLE (apixaban for reduction in stroke and other thromboembolic events in atr...

journal_title：BMJ (Clinical research ed.)

authors： Jaspers Focks J,Brouwer MA,Wojdyla DM,Thomas L,Lopes RD,Washam JB,Lanas F,Xavier D,Husted S,Wallentin L,Alexander JH,Granger CB,Verheugt FW

更新日期：2016-06-15 00:00:00

abstract：OBJECTIVE:To evaluate the effect of financial incentives on four clinical quality indicators common to pay for performance plans in the United Kingdom and at Kaiser Permanente in California. DESIGN:Longitudinal analysis. SETTING:35 medical facilities of Kaiser Permanente Northern California, 1997-2007. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Lester H,Schmittdiel J,Selby J,Fireman B,Campbell S,Lee J,Whippy A,Madvig P

更新日期：2010-05-11 00:00:00

abstract：OBJECTIVE:To assess the effect of weight loss induced by a very low energy diet on moderate and severe obstructive sleep apnoea in obese men. Design Single centre, two arm, parallel, randomised, controlled, open label trial. Blocked randomisation procedure used for treatment allocation. Setting Outpatient obesity clini...

journal_title：BMJ (Clinical research ed.)

authors： Johansson K,Neovius M,Lagerros YT,Harlid R,Rössner S,Granath F,Hemmingsson E

更新日期：2009-12-03 00:00:00

abstract：:National allocation of resources to regional health authorities and by them to districts is now determined by a weighted capitation formula. The national formula was derived from regression analysis, with hospital utilisation as an index of need for health care--a method which has fundamental limitations. This paper a...

journal_title：BMJ (Clinical research ed.)

authors： Sheldon TA,Smith GD,Bevan G

更新日期：1993-03-27 00:00:00