Commissioning and initial experience with the first clinical gantry-mounted proton therapy system.

Abstract:

:The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry-mounted, single-room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes-Jewish Hospital in St. Louis, MO, USA. The Mevion S250 system integrates a compact synchrocyclotron with a C-inner gantry, an image guidance system and a 6D robotic couch into a beam delivery platform. We present our commissioning process and initial clinical experience, including i) CT calibration; ii) beam data acquisition and machine characteristics; iii) dosimetric commissioning of the treatment planning system; iv) validation through the Imaging and Radiation Oncology Core credentialing process, including irradiations on the spine, prostate, brain, and lung phantoms; v) evaluation of localization accuracy of the image guidance system; and vi) initial clinical experience. Clinically, the system operates well and has provided an excellent platform for the treatment of diseases with protons.

journal_name

J Appl Clin Med Phys

authors

Zhao T,Sun B,Grantham K,Rankine L,Cai B,Goddu SM,Santanam L,Knutson N,Zhang T,Reilly M,Bottani B,Bradley J,Mutic S,Klein EE

doi

10.1120/jacmp.v17i2.5868

subject

Has Abstract

pub_date

2016-03-08 00:00:00

pages

24-40

issue

2

issn

1526-9914

journal_volume

17

pub_type

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