Abstract:
:The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry-mounted, single-room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes-Jewish Hospital in St. Louis, MO, USA. The Mevion S250 system integrates a compact synchrocyclotron with a C-inner gantry, an image guidance system and a 6D robotic couch into a beam delivery platform. We present our commissioning process and initial clinical experience, including i) CT calibration; ii) beam data acquisition and machine characteristics; iii) dosimetric commissioning of the treatment planning system; iv) validation through the Imaging and Radiation Oncology Core credentialing process, including irradiations on the spine, prostate, brain, and lung phantoms; v) evaluation of localization accuracy of the image guidance system; and vi) initial clinical experience. Clinically, the system operates well and has provided an excellent platform for the treatment of diseases with protons.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Zhao T,Sun B,Grantham K,Rankine L,Cai B,Goddu SM,Santanam L,Knutson N,Zhang T,Reilly M,Bottani B,Bradley J,Mutic S,Klein EEdoi
10.1120/jacmp.v17i2.5868subject
Has Abstractpub_date
2016-03-08 00:00:00pages
24-40issue
2issn
1526-9914journal_volume
17pub_type
杂志文章abstract::The purpose of this study is to find the uncertainties in the reconstruction of MR compatible ring-tandem intracavitary applicators of high-dose rate image-based brachytherapy treatment planning using rigid registration of 3D MR and CT image fusion. Tandem and ring reconstruction in MR image based brachytherapy planni...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v15i2.4206
更新日期:2014-03-06 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12992
更新日期:2020-10-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12227
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i1.5714
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abstract::The purpose of this study was to investigate amplitude gating combined with a coached breathing strategy for 10 MV flattening filter-free (FFF) volumetric-modulated arc therapy (VMAT) on the Varian TrueBeam linac. Ten patient plans for VMAT SABR liver were created using the Eclipse treatment planning system (TPS). The...
journal_title:Journal of applied clinical medical physics
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doi:10.1120/jacmp.v16i4.5350
更新日期:2015-07-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v5i3.2026
更新日期:2004-07-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i3.4203
更新日期:2013-05-06 00:00:00
abstract::Substantial disagreement exists over appropriate PET segmentation techniques for non-small cell lung cancer. Currently, no segmentation algorithm explicitly considers tumor motion in determining tumor borders. We developed an automatic PET segmentation model as a function of target volume, motion extent, and source-to...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v15i1.4600
更新日期:2014-01-06 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2013-11-04 00:00:00
abstract:PURPOSE:To report our early experiences with failure mode and effects analysis (FMEA) in a community practice setting. METHODS:The FMEA facilitator received extensive training at the AAPM Summer School. Early efforts focused on department education and emphasized the need for process evaluation in the context of high ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12190
更新日期:2017-11-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i1.3585
更新日期:2012-01-05 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v11i1.3146
更新日期:2010-01-28 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i1.5049
更新日期:2015-01-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12841
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:Prescription practice in SRS plans for brain tumors differs significantly for different modalities. In this retrospective study, the strategies to optimize SRS plans for brain tumors with volumetric arc therapy (VMAT) were presented. METHODS:Fifty clinically treated cases were stratified by the maximum target ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12818
更新日期:2020-03-01 00:00:00
abstract::Reducing the treatment time for IMRT patients is highly desirable. The objective of this work was to evaluate the new clinical Siemens KonRad inverse treatment planning system (TPS) and compare it to the CMS XiO TPS with special emphasis on the segmentation efficiency. For head and neck, liver and prostate cancer pati...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2008-07-14 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2011-01-31 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2013-07-08 00:00:00
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journal_title:Journal of applied clinical medical physics
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更新日期:2015-09-08 00:00:00
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journal_title:Journal of applied clinical medical physics
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更新日期:2018-11-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
abstract::This article compares two algorithms for determining beam weights and wedge filters for conformal treatment planning. One algorithm, which is based on dose-gradient analysis, provides analytic formulas for determining beam weights, wedge angles, and collimator angles (i.e., wedge orientations) so that the dose distrib...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v3i3.2562
更新日期:2002-07-01 00:00:00
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2013-11-04 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12895
更新日期:2020-07-01 00:00:00