Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort.

Abstract:

BACKGROUND:There is limited longitudinal data available on the natural history of meniscal tears especially in middle-aged adults with a low prevalence of osteoarthritis (OA). The aim of this study was to describe the natural history of meniscal tears over 8 years and the relationship with change in knee pain and structures. METHODS:One hundred ninety eight participants [mean age 47 (28-63); 57% female] were studied at baseline and 8 years later. Approximately half were the adult offspring of subjects who had a knee replacement performed for knee OA and the remainder were randomly selected controls. Meniscal tears/extrusion, cartilage volume/defects, bone marrow lesions (BMLs) and effusion were assessed on MRI. Knee pain was assessed using the Western Ontario and McMaster Universities Osteoarthritis Index. RESULTS:22% of the participants had at least one meniscal tear at any site at baseline. Over 8 years, 16% of the participants had an increase in severity of meniscal tears while none improved. Increase in meniscal tear score was associated with worsening knee pain (β = +2.81 (+1.40, +4.22)), with offspring having a significantly greater increase in pain severity compared to controls. BMI and presence of osteophytes at baseline, but not knee injury, predicted change in tears, whereas change in meniscal tears was independently associated with cartilage volume loss, change in BMLs and change in meniscal extrusion. CONCLUSION:Change in meniscal tears shares risk factors with knee OA and is independently associated with worsening knee pain and structural damage suggesting that meniscal tears are on the knee OA causal pathway.

authors

Khan HI,Aitken D,Ding C,Blizzard L,Pelletier JP,Martel-Pelletier J,Cicuttini F,Jones G

doi

10.1186/s12891-015-0862-1

subject

Has Abstract

pub_date

2016-01-05 00:00:00

pages

4

issn

1471-2474

pii

10.1186/s12891-015-0862-1

journal_volume

17

pub_type

杂志文章
  • 2D-fluoroscopic based navigation for Gamma 3 nail insertion versus conventional procedure- a feasibility study.

    abstract:BACKGROUND:Intramedullary nailing is a standard surgical procedure for fixation of proximal femoral fractures, but is associated with considerable radiation exposure for controlling the implant placement, due to the percutaneous insertion technique.The aim of this study was the evaluation of potential benefits of 2D-fl...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-14-74

    authors: Wilharm A,Marintschev I,Hofmann GO,Gras F

    更新日期:2013-02-28 00:00:00

  • Surgery versus conservative treatment in patients with type A distal radius fractures, a randomized controlled trial.

    abstract:BACKGROUND:Fractures of the distal radius are common and account for an estimated 17% of all fractures diagnosed. Two-thirds of these fractures are displaced and require reduction. Although distal radius fractures, especially extra-articular fractures, are considered to be relatively harmless, inadequate treatment may ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2474-15-90

    authors: Walenkamp MM,Goslings JC,Beumer A,Haverlag R,Leenhouts PA,Verleisdonk EJ,Liem RS,Sintenie JB,Bronkhorst MW,Winkelhagen J,Schep NW

    更新日期:2014-03-19 00:00:00

  • Effects of low-dye taping on plantar pressure pre and post exercise: an exploratory study.

    abstract:BACKGROUND:Low-Dye taping is used for excessive pronation at the subtalar joint of the foot. Previous research has focused on the tape's immediate effect on plantar pressure. Its effectiveness following exercise has not been investigated. Peak plantar pressure distribution provides an indirect representation of subtala...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-10-40

    authors: Nolan D,Kennedy N

    更新日期:2009-04-21 00:00:00

  • Low urine pH and acid excretion do not predict bone fractures or the loss of bone mineral density: a prospective cohort study.

    abstract:BACKGROUND:The acid-ash hypothesis, the alkaline diet, and related products are marketed to the general public. Websites, lay literature, and direct mail marketing encourage people to measure their urine pH to assess their health status and their risk of osteoporosis.The objectives of this study were to determine wheth...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-11-88

    authors: Fenton TR,Eliasziw M,Tough SC,Lyon AW,Brown JP,Hanley DA

    更新日期:2010-05-10 00:00:00

  • Increase of chronic low back pain prevalence in a medium-sized city of southern Brazil.

    abstract:BACKGROUND:Chronic low back pain (CLBP) is a highly disabling morbidity with high social, economic and individual effects. Demographic, occupational and behavioral changes that took place in Brazil over the last decade are related with an increasing burden of chronic conditions. Despite these changes, comparison studie...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-14-155

    authors: Meucci RD,Fassa AG,Paniz VM,Silva MC,Wegman DH

    更新日期:2013-05-01 00:00:00

  • Effects and predictors of shoulder muscle massage for patients with posterior shoulder tightness.

    abstract:BACKGROUND:Clinical approaches like mobilization, stretching, and/or massage may decrease shoulder tightness and improve symptoms in subjects with stiff shoulders. We investigated the effect and predictors of effectiveness of massage in the treatment of patients with posterior shoulder tightness. METHODS:A randomized ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2474-13-46

    authors: Yang JL,Chen SY,Hsieh CL,Lin JJ

    更新日期:2012-03-27 00:00:00

  • Arthroscopic reduction of an irreducible distal radioulnar joint in Galeazzi fracture-dislocation due to a fragment of the ulnar styloid: a case report.

    abstract:BACKGROUND:There are only a few published case reports of irreducible Galeazzi fracture-dislocation, and patients in these studies had undergone reduction by open surgical methods. Arthroscopy for the distal radioulnar joint of the wrist joint has recently been used for wrist pathology. We aim to describe the surgical ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-019-2735-5

    authors: Iwamae M,Yano K,Kaneshiro Y,Sakanaka H

    更新日期:2019-07-31 00:00:00

  • The effect of posterior capsule repair upon post-operative hip dislocation following primary total hip arthroplasty.

    abstract:BACKGROUND:Herein, we evaluated, retrospectively, the effect of posterior capsular repair upon postoperative hip dislocation subsequent to total hip arthroplasty (THA) incorporating a posterolateral approach. METHODS:A total of 181 patients undergoing 204 primary non-complicated THA surgical procedures in the period f...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-9-29

    authors: Tsai SJ,Wang CT,Jiang CC

    更新日期:2008-02-29 00:00:00

  • A new finger-preserving procedure as an alternative to amputation in recurrent severe Dupuytren contracture of the small finger.

    abstract:BACKGROUND:Recurrent severe Dupuytren contracture of the small finger's proximal interphalangeal (PIP) joint is a difficult problem. Further surgery carries high risk of complications and poor outcome. Patients are often offered finger amputation. We have devised a novel surgical procedure consisting of middle phalanx ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-019-2701-2

    authors: Eiriksdottir A,Atroshi I

    更新日期:2019-07-09 00:00:00

  • Anamnestic risk factor questionnaire as reliable diagnostic instrument for osteoporosis (reduced bone morphogenic density).

    abstract:BACKGROUND:Osteoporosis is a major health problem worldwide, and is included in the WHO list of the top 10 major diseases. However, it is often undiagnosed until the first fracture occurs, due to inadequate patient education and lack of insurance coverage for screening tests. Anamnestic risk factors like positive famil...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-12-187

    authors: Kolios L,Takur C,Moghaddam A,Hitzler M,Schmidt-Gayk H,Suda AJ,Höner B,Grützner PA,Wölfl C

    更新日期:2011-08-17 00:00:00

  • Monobloc implants in cementless total hip arthroplasty in patients with Legg-Calve-Perthes disease: a long-term follow-up.

    abstract:BACKGROUND:The purpose of this study was to evaluate 10-year outcomes in cementless monobloc total hip arthroplasty (THA) in a group of hips with Legg-Calve-Perthes disease (LCPD). METHODS:We reviewed 71 patients (88 hips) who underwent cementless THA with a diagnosis of LCPD from 2003 to 2009. From the total of 71 pa...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-017-1748-1

    authors: Luo ZY,Wang HY,Wang D,Pan H,Pei FX,Zhou ZK

    更新日期:2017-09-05 00:00:00

  • Risk assessment for prolonged sickness absence due to musculoskeletal disorders: protocol for a prospective cohort study.

    abstract:BACKGROUND:Musculoskeletal disorders are the leading cause of sickness absence and disability pension in Norway. There is strong evidence that long-term sickness absence due to musculoskeletal disorders are associated with a reduced probability of return to work (RTW). A way to meet the economic and resource-demanding ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03354-7

    authors: Tveter AT,Øiestad BE,Rysstad TL,Aanesen F,Tingulstad A,Småstuen MC,Grotle M

    更新日期:2020-05-25 00:00:00

  • Educational needs in patients with spondyloarthritis in Sweden - a mixed-methods study.

    abstract:BACKGROUND:There is a demand for a flexible and individually tailored patient education to meet patients' specific needs and priorities, but this area has seldom been studied in patients with spondyloarthritis (SpA), a family of inflammatory rheumatic diseases. The aim of the present study was to identify needs and pri...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-017-1689-8

    authors: Haglund E,Bremander A,Bergman S,Larsson I

    更新日期:2017-08-02 00:00:00

  • Biomechanical and functional indicators in male semiprofessional soccer players with increased hip alpha angles vs. amateur soccer players.

    abstract:BACKGROUND:Femoroacetabular impingement (FAI) is predominant in young male athletes, but not much is known about gait differences in cases of increased hip alpha angles. In our study, the hip alpha angle of Nötzli of soccer players was quantified on the basis of magnetic resonance imaging (MRI) with axial oblique seque...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-15-88

    authors: Lahner M,von Schulze Pellengahr C,Walter PA,Lukas C,Falarzik A,Daniilidis K,von Engelhardt LV,Abraham C,Hennig EM,Hagen M

    更新日期:2014-03-16 00:00:00

  • Use of imaging biomarkers to assess perfusion and glucose metabolism in the skeletal muscle of dystrophic mice.

    abstract:BACKGROUND:Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease that affects 1 in 3500 boys. The disease is characterized by progressive muscle degeneration that results from mutations in or loss of the cytoskeletal protein, dystrophin, from the glycoprotein membrane complex, thus increasing the suscepti...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-12-127

    authors: Ahmad N,Welch I,Grange R,Hadway J,Dhanvantari S,Hill D,Lee TY,Hoffman LM

    更新日期:2011-06-04 00:00:00

  • Design modifications of high-flexion TKA do not improve short term clinical and radiographic outcomes.

    abstract:BACKGROUND:The prosthesis of contemporary total knee arthroplasty (TKA) has been modified to provide a more familiar environment for higher flexion angle of the replaced knee. The design modifications continue based on evidence reported in the literature. However, whether these modifications of the prosthesis design le...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-15-433

    authors: Seo JG,Moon YW,Chang MJ,Jo BC,Park YB,Lim DS,Lee BH

    更新日期:2014-12-15 00:00:00

  • Differences in Achilles tendon stiffness in people with gout: a pilot study.

    abstract:BACKGROUND:Gout has been associated with weaker foot/leg muscles and altered gait patterns. There is also evidence of on-going foot pain and an increased risk of tendinopathy, with the Achilles and patella tendons most frequently affected in gout. Additionally, the inflammation associated with gout may change tissue el...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03598-3

    authors: Otter S,Payne C,Jones AM,Webborn N,Watt P

    更新日期:2020-10-07 00:00:00

  • Physiological responses to low-force work and psychosocial stress in women with chronic trapezius myalgia.

    abstract:BACKGROUND:Repetitive and stressful work tasks have been linked to the development of pain in the trapezius muscle, although the underlying mechanisms still remain unclear. In earlier studies, it has been hypothesized that chronic muscle pain conditions are associated with imbalance in the autonomic nervous system, pre...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-10-63

    authors: Sjörs A,Larsson B,Dahlman J,Falkmer T,Gerdle B

    更新日期:2009-06-07 00:00:00

  • Classifying health-related quality of life outcomes of total hip arthroplasty.

    abstract:BACKGROUND:Primary total hip arthroplasty (THA) is an effective treatment for hip osteoarthritis, assessed by whatever distribution-based measures of responsiveness. Yet, the group level evaluation has provided very little evidence contributes to our understanding of the large variation of treatment outcome. The object...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-6-48

    authors: Xu M,Garbuz DS,Kuramoto L,Sobolev B

    更新日期:2005-09-06 00:00:00

  • Real-time detection of antibiotics cytotoxicity in rabbit periosteal cells using microfluidic devices with comparison to conventional culture assays.

    abstract:BACKGROUND:Local antibiotic application has been widely used in orthopedic surgery. The dose-related toxicity of antibiotics towards periosteal tissues and resulting effects on osteogenic expression are yet to be studied. METHODS:Periosteal cells harvested from the medial tibia of New Zealand White rabbits were used. ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-019-2705-y

    authors: Chiu CH,Lei KF,Chan YS,Ueng SWN,Chen AC

    更新日期:2019-07-26 00:00:00

  • Prediction of chronic disability in work-related musculoskeletal disorders: a prospective, population-based study.

    abstract:BACKGROUND:Disability associated with work-related musculoskeletal disorders is an increasingly serious societal problem. Although most injured workers return quickly to work, a substantial number do not. The costs of chronic disability to the injured worker, his or her family, employers, and society are enormous. A me...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-5-14

    authors: Turner JA,Franklin G,Fulton-Kehoe D,Egan K,Wickizer TM,Lymp JF,Sheppard L,Kaufman JD

    更新日期:2004-05-24 00:00:00

  • The roles of lumbar load thresholds in cumulative lifting exposure to predict disk protrusion in an Asian population.

    abstract:BACKGROUND:The purpose of this study was to determine whether a specific threshold per lifting movement, the accumulation above which best predicts lumbar disk protrusion, exists or the total lifting load should be considered. METHODS:This was a retrospective study. Subjects with various lifting exposures were recruit...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-3167-y

    authors: Hung IY,Shih TT,Chen BB,Liou SH,Ho IK,Guo YL

    更新日期:2020-03-16 00:00:00

  • Construct validity of functional capacity tests in healthy workers.

    abstract:BACKGROUND:Functional Capacity (FC) is a multidimensional construct within the activity domain of the International Classification of Functioning, Disability and Health framework (ICF). Functional capacity evaluations (FCEs) are assessments of work-related FC. The extent to which these work-related FC tests are associa...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-14-180

    authors: Lakke SE,Soer R,Geertzen JH,Wittink H,Douma RK,van der Schans CP,Reneman MF

    更新日期:2013-06-08 00:00:00

  • Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid.

    abstract:BACKGROUND:Osteoarthritis (OA) and rheumatoid arthritis (RA) are diseases which result in the degeneration of the joint surface articular cartilage. Matrix metalloproteinases (MMPs) are enzymes that aid in the natural remodelling of tissues throughout the body including cartilage. However, some MMPs have been implicate...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-13-126

    authors: Heard BJ,Martin L,Rattner JB,Frank CB,Hart DA,Krawetz R

    更新日期:2012-07-23 00:00:00

  • Delta III reverse shoulder arthroplasty in the treatment of complex 3- and 4-part fractures of the proximal humerus: 6 to 42 months of follow up.

    abstract:BACKGROUND:There is a growing tendency for complex proximal humerus fractures (PHF) in osteoporotic patients to be treated with reverse shoulder arthroplasty (RSA). It has been proposed that RSA has more benefits than other treatment options. The aim of our study was to investigate preoperative characteristics as well ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-14-231

    authors: Mattiassich G,Marcovici LL,Krifter RM,Ortmaier R,Wegerer P,Kroepfl A

    更新日期:2013-08-08 00:00:00

  • Tibiofemoral osteoarthritis affects quality of life and function in elderly Koreans, with women more adversely affected than men.

    abstract:BACKGROUND:The prevalence of knee osteoarthritis(OA) in East Asia is as common for men and even higher for women than that reported in the Caucasian population. Since both population aging and economic growth have taken place at a much faster pace in Asian countries, such as South Korea, one would expect knee OA to bec...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-11-129

    authors: Kim I,Kim HA,Seo YI,Song YW,Hunter DJ,Jeong JY,Kim DH

    更新日期:2010-06-22 00:00:00

  • Osteoporosis-related life habits and knowledge about osteoporosis among women in El Salvador: a cross-sectional study.

    abstract:BACKGROUND:Osteoporosis is a systemic skeletal disorder, characterized by reduced bone mass, deterioration of bone structure, increased bone fragility, and increased fracture risk. It is more frequent to find among women than men at a 4:1 ratio. Evidence suggests that to adopt changes on some life habits can prevent or...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-5-29

    authors: Hernandez-Rauda R,Martinez-Garcia S

    更新日期:2004-08-26 00:00:00

  • Effectiveness and cost-effectiveness of rehabilitation after lumbar disc surgery (REALISE): design of a randomised controlled trial.

    abstract:BACKGROUND:Patients who undergo lumbar disc surgery for herniated discs, are advocated two different postoperative management strategies: a watchful waiting policy, or referral for rehabilitation immediately after discharge from the hospital. A direct comparison of the effectiveness and cost-effectiveness of these two ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2474-14-124

    authors: Oosterhuis T,van Tulder M,Peul W,Bosmans J,Vleggeert-Lankamp C,Smakman L,Arts M,Ostelo R

    更新日期:2013-04-05 00:00:00

  • Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study.

    abstract:BACKGROUND:There is emerging evidence for a beneficial effect of meat consumption on the musculoskeletal system. However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective cohort study to examine the relationship between meat consumption and risk of primary hip and knee r...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-12-17

    authors: Wang Y,Simpson JA,Wluka AE,English DR,Giles GG,Graves S,Cicuttini FM

    更新日期:2011-01-16 00:00:00

  • The effects of necrotic lesion size and orientation of the femoral component on stress alterations in the proximal femur in hip resurfacing - a finite element simulation.

    abstract:BACKGROUND:Due to the advantages of its bone-conserving nature, hip resurface arthroplasty (HRA) has recently gained the interest of orthopedic surgeons for the treatment of young and active patients who have osteonerosis of the femoral head. However, in long-term follow-up studies after HRA, narrowing of the femoral n...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-15-262

    authors: Tai CL,Chen YC,Hsieh PH

    更新日期:2014-08-05 00:00:00