The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease.

Abstract:

:The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to the destruction of normal architecture and progressive fibrosis. Increasing evidence indicates that diffuse lung disease results from an imbalance between the pro-inflammatory and anti-inflammatory mechanisms, with a persistent imbalance that favors pro-inflammatory mediators dictating the development of chronic diffuse lung disease. This review focuses on the mediators that influence this imbalance.

journal_name

Respir Res

journal_title

Respiratory research

authors

Keane MP,Strieter RM

doi

10.1186/rr177

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

5

eissn

1465-9921

issn

1465-993X

journal_volume

3

pub_type

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