当前位置： SCI文献检索 > BMC Complementary and Alternative Medicine期刊下所有文献 > Protective effect of Suxiao jiuxin pill, a traditional Chinese medicine, against acute myocardial ischemia in dogs.

Protective effect of Suxiao jiuxin pill, a traditional Chinese medicine, against acute myocardial ischemia in dogs.

Abstract：

BACKGROUND:The purpose of this study was to investigate the effect of Suxiao Jiuxin Pill (SX), a traditional Chinese medicine, on acute myocardial ischemia induced by coronary occlusion in anesthetized dogs. METHODS:Acute myocardial ischemia model was established by ligating the left anterior descending artery to reduce flow by 90 %. Adult mongrel dogs were randomly divided into six groups: model, SX high dose, SX middle dose, SX low dose, Isosorbide dinitrate (ISD) and Sham groups. Adult mongrel dogs were anesthetized and instrumented for measurements of heart rate (HR), mean arterial pressure (MAP), left ventricular systolic pressure (LVSP), left ventricular dP/dt, coronary blood flow (CBF), myocardial blood flow (MBF), coronary vascular resistance (CVR), and epicardial electrocardiogram (EECG). After administration with SX, changes in hemodynamics were recorded. Serum enzymes and blood gas analysis were also detected. RESULTS:SX has a dose-dependent effect on the reduction of infarct size. Besides, SX exerted a notable inhibition on the elevation of serum creatine kinase MB (CK-MB), lactate dehydrogenase (LDH), malondialdehyde (MDA), and elevation in the superoxide dismutase (SOD) activity. SX also showed a capacity to recover myocardial function by significantly reducing MAP, CVR, LVSP, left ventricular systolic pressure (LVEDP), systolic blood pressure (SBP), diastolic blood pressure (SDP), and increasing CBF and myocardial blood flow (MBF). In addition, SX high dose group markedly reduced total mV of ST segment elevation (Σ-ST), total number of sites with this degree of ST segment elevation (N-ST) and oxygen extraction ratio (O2 Extr). CONCLUSION:SX can improve hemodynamic and myocardial oxygen metabolism, reduce the degree and scope of myocardial ischemia, and hence exert notable anti-anginal ischaemic effect.

journal_name

BMC Complement Altern Med

journal_title

BMC complementary and alternative medicine

authors

Lu Z,Zhang Y,Zhuang P,Zhang J,Zhou H,Zhang M,Yang X,Wang J,Liu D,Tong Y

doi

10.1186/s12906-015-0908-9

subject

Has Abstract

pub_date

2015-10-19 00:00:00

pages

373

issn

1472-6882

pii

10.1186/s12906-015-0908-9

journal_volume

15

pub_type

杂志文章

相关文献

BMC Complementary and Alternative Medicine文献大全
  • Samsoeum, a traditional herbal medicine, elicits apoptotic and autophagic cell death by inhibiting Akt/mTOR and activating the JNK pathway in cancer cells.

    abstract：BACKGROUND:Samsoeum (SSE), a traditional herbal formula, has been widely used to treat cough, fever, congestion, and emesis for centuries. Recent studies have demonstrated that SSE retains potent pharmacological efficiency in anti-allergic and anti-inflammatory reactions. However, the anti-cancer activity of SSE and it...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-233

    authors： Kim A,Yim NH,Ma JY

    更新日期：2013-09-23 00:00:00

  • Development and implementation of an herbal and natural product elective in undergraduate medical education.

    abstract：BACKGROUND:Medical students have consistently expressed interest in learning about alternative healing modalities, especially herbal and natural products. To fill this void in medical education at our institution, a novel elective was developed and implemented for fourth year medical students. This herbal/natural produ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-12-57

    authors： Karpa K

    更新日期：2012-05-22 00:00:00

  • Mindfulness, perceived stress, and subjective well-being: a correlational study in primary care health professionals.

    abstract：BACKGROUND:Primary health care professionals (PHPs) usually report high levels of distress and burnout symptoms related to job strain. Mindfulness, defined as non-judgmental-present-moment awareness, seems to be a moderator in the causal association between life stressors and well-being. This study aimed to verify corr...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-015-0823-0

    authors： Atanes AC,Andreoni S,Hirayama MS,Montero-Marin J,Barros VV,Ronzani TM,Kozasa EH,Soler J,Cebolla A,Garcia-Campayo J,Demarzo MM

    更新日期：2015-09-02 00:00:00

  • Chemical analysis, inhibition of biofilm formation and biofilm eradication potential of Euphorbia hirta L. against clinical isolates and standard strains.

    abstract：BACKGROUND:The frequent occurrences of antibiotic-resistant biofilm forming pathogens have become global issue since various measures that had been taken to curb the situation led to failure. Euphorbia hirta, is a well-known ethnomedicinal plant of Malaysia with diverse biological activities. This plant has been used w...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-346

    authors： Perumal S,Mahmud R

    更新日期：2013-12-09 00:00:00

  • Beneficial effect of compound essential oil inhalation on central fatigue.

    abstract：BACKGROUNDS:Although the physical and mental enhancement effect of essential oils have been proved, the beneficial effect of essential oil in central fatigue remains unclear. In this study, we extracted essential oils from nine aromatic plants to make a compound essential oil, and detected the therapeutic effect of cen...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-018-2375-6

    authors： Han C,Li F,Tian S,Liu Y,Xiao H,Wu X,Zhang W,Zhang W,Mao M

    更新日期：2018-11-26 00:00:00

  • Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway.

    abstract：BACKGROUND:Cerebral ischemia is the second-leading cause of death and the main cause of permanent adult disabilities worldwide. Qingkailing (QKL) injection, a patented Chinese medicine approved by the China Food and Drug Administration, has been widely used in clinical practice to treat cerebral ischemia in China. The ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-019-2703-5

    authors： Ma C,Wang X,Xu T,Yu X,Zhang S,Liu S,Gao Y,Fan S,Li C,Zhai C,Cheng F,Wang Q

    更新日期：2019-11-20 00:00:00

  • Hypotensive effect of Gentiana floribunda is mediated through Ca++ antagonism pathway.

    abstract：BACKGROUND:Gentiana floribunda was investigated for the possible hypotensive and vasodilator activities in an attempt to rationalize its traditional use in hypertension. METHODS:The crude extract of Gentiana floribunda (Gf.Cr) was studied in anaesthetized rats and isolated thoracic aorta tissues. RESULTS:Gf.Cr which ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-12-121

    authors： Khan AU,Mustafa MR,Khan AU,Murugan DD

    更新日期：2012-08-11 00:00:00

  • Anti-lipoapoptotic effect of Artemisia capillaris extract on free fatty acids-induced HepG2 cells.

    abstract：BACKGROUND:Artemisia capillaris (AC) has been recognized as one of the promising candidates for hepatoprotective, hypoglycemic, hypolipidemic, antiobesitic and anti-inflammatory therapeutic effectiveness. This study evaluated the inherent mechanism and anti-apoptotic activity of 30% ethanol extract of AC (AC extract) 1...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-14-253

    authors： Jang E,Shin MH,Kim KS,Kim Y,Na YC,Woo HJ,Kim Y,Lee JH,Jang HJ

    更新日期：2014-07-19 00:00:00

  • What do clinicians want? Interest in integrative health services at a North Carolina academic medical center.

    abstract：BACKGROUND:Use of complementary medicine is common, consumer driven and usually outpatient focused. We wished to determine interest among the medical staff at a North Carolina academic medical center in integrating diverse therapies and services into comprehensive care. METHODS:We conducted a cross sectional on-line s...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-7-5

    authors： Kemper KJ,Dirkse D,Eadie D,Pennington M

    更新日期：2007-02-09 00:00:00

  • Dig1 protects against locomotor and biochemical dysfunctions provoked by Roundup.

    abstract：BACKGROUND:Plant medicinal extracts may be claimed to prevent or cure chemical intoxications. Few of these are tested for their mechanisms of actions in vivo and for their cellular impacts. In 2011, we demonstrated that hepatic cell mortality induced by environmentally realistic levels of the widely used herbicide Roun...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1226-6

    authors： Gress S,Laurant C,Defarge N,Travert C,Séralini GÉ

    更新日期：2016-07-22 00:00:00

  • Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats.

    abstract：BACKGROUND:Liriope platyphylla has long been reported as a therapeutic drug for treatment of various human chronic diseases including inflammation, diabetes, neurodegenerative disorders, obesity, and atopic dermatitis. To investigate the laxative effects of L. platyphylla, alterations in excretion parameters, histologi...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-333

    authors： Kim JE,Lee YJ,Kwak MH,Ko J,Hong JT,Hwang DY

    更新日期：2013-11-26 00:00:00

  • Direct and indirect risk associated with the use of dietary supplements among persons with dementia in a Norwegian memory clinic.

    abstract：BACKGROUND:The use of dietary supplements (DS) is common among persons with dementia. Direct risks associated with DS use include adverse events and DS-drug interactions. A direct risk is a risk caused by the treatment itself. Indirect risks are related to the treatment setting, such as the conditions of use, and not t...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-1765-5

    authors： Risvoll H,Giverhaug T,Halvorsen KH,Waaseth M,Musial F

    更新日期：2017-05-12 00:00:00

  • Transcendental Meditation for the improvement of health and wellbeing in community-dwelling dementia caregivers [TRANSCENDENT]: a randomised wait-list controlled trial.

    abstract：BACKGROUND:Dementia is a prevalent neurodegenerative disorder affecting an estimated 24.3 million people across the globe. The burden on those caring for people with dementia is substantial, with widespread implications for the caregiver, the care recipient and the community. Relaxation techniques, such as Transcendent...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1186/s12906-015-0666-8

    authors： Leach MJ,Francis A,Ziaian T

    更新日期：2015-05-08 00:00:00

  • Adding Chinese herbal medicine to conventional therapy brings cognitive benefits to patients with Alzheimer's disease: a retrospective analysis.

    abstract：BACKGROUND:Conventional therapy (CT) such as donepezil and memantine are well-known short-term treatments for the symptoms of Alzheimer's disease (AD). The efficacy of them, however, drops below baseline level after 9 months. In China, herbal therapy as a complementary therapy is very popular. Should conventional thera...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-2040-5

    authors： Shi J,Ni J,Lu T,Zhang X,Wei M,Li T,Liu W,Wang Y,Shi Y,Tian J

    更新日期：2017-12-13 00:00:00

  • Physician and patient attitudes towards complementary and alternative medicine in obstetrics and gynecology.

    abstract：BACKGROUND:In the U.S., complementary and alternative medicine (CAM) use is most prevalent among reproductive age, educated women. We sought to determine general attitudes and approaches to CAM among obstetric and gynecology patients and physicians. METHODS:Obstetrician-gynecologist members of the American Medical Ass...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-8-35

    authors： Furlow ML,Patel DA,Sen A,Liu JR

    更新日期：2008-06-26 00:00:00

  • The effects of the court-type Thai traditional massage on anatomical relations, blood flow, and skin temperature of the neck, shoulder, and arm.

    abstract：BACKGROUND:Court-type Thai traditional massage (CTTM) has specific major signal points (MaSP) for treating musculoskeletal conditions. The objectives of this study are to investigate the anatomical surfaces and structures of MaSPs, and to examine blood flow (BF) and skin temperature (ST) changes after applying pressure...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1282-y

    authors： Plakornkul V,Vannabhum M,Viravud Y,Roongruangchai J,Mutirangura P,Akarasereenont P,Laohapand T

    更新日期：2016-09-15 00:00:00

  • Brazilian propolis ethanol extract and its component kaempferol induce myeloid-derived suppressor cells from macrophages of mice in vivo and in vitro.

    abstract：BACKGROUND:Brazilian green propolis is produced by mixing secretions from Africanized honey bees with exudate, mainly from Baccharis dracunculifolia. Brazilian propolis is especially rich in flavonoids and cinammic acid derivatives, and it has been widely used in folk medicine owing to its anti-inflammatory, anti-viral...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-018-2198-5

    authors： Kitamura H,Saito N,Fujimoto J,Nakashima KI,Fujikura D

    更新日期：2018-05-02 00:00:00

  • Effect of transcutaneous acupoint electrical stimulation on propofol sedation: an electroencephalogram analysis of patients undergoing pituitary adenomas resection.

    abstract：BACKGROUND:Transcutaneous acupoint electrical stimulation (TAES) as a needleless acupuncture has the same effect like traditional manual acupuncture. The combination of TAES and anesthesia has been proved valid in enhancing the anesthetic effects but its mechanisms are still not clear. METHODS:In this study, we invest...

    journal_title：BMC complementary and alternative medicine

    pub_type： 临床试验,杂志文章

    doi：10.1186/s12906-016-1008-1

    authors： Liu X,Wang J,Wang B,Wang YH,Teng Q,Yan J,Wang S,Wan Y

    更新日期：2016-01-27 00:00:00

  • Abalone visceral extract inhibit tumor growth and metastasis by modulating Cox-2 levels and CD8+ T cell activity.

    abstract：BACKGROUND:Abalone has long been used as a valuable food source in East Asian countries. Although the nutritional importance of abalone has been reported through in vitro and in vivo studies, there is little evidence about the potential anti-tumor effects of abalone visceral extract. The aim of the present study is to ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-10-60

    authors： Lee CG,Kwon HK,Ryu JH,Kang SJ,Im CR,Ii Kim J,Im SH

    更新日期：2010-10-20 00:00:00

  • Evaluation of selected biological capacities of Baeckea frutescens.

    abstract：BACKGROUND:Baeckea frutescens is a natural remedy recorded to be used in curing various health conditions. In Peninsular Malaysia, B. frutescens is found on the mountain tops, quartz ridge and sandy coasts. To our knowledge, there is only limited published literature on B. frutescens. METHODS:B. frutescens leaf crude ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-015-0712-6

    authors： Navanesan S,Wahab NA,Manickam S,Sim KS

    更新日期：2015-06-17 00:00:00

  • Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88.

    abstract：BACKGROUNDS:Inflammation is recognized as the key pathological mechanism of type 2 diabetes. The hypoglyceamic effects of berberine (BBR) are related to the inhibition of the inflammatory response, but the mechanism is not completely clear. METHODS:The inflammatory polarization of Raw264.7 cells and primary peritoneal...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-019-2710-6

    authors： Gong J,Li J,Dong H,Chen G,Qin X,Hu M,Yuan F,Fang K,Wang D,Jiang S,Zhao Y,Huang W,Huang Z,Lu F

    更新日期：2019-11-19 00:00:00

  • Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2).

    abstract：BACKGROUND:Paclitaxel (taxol) is a potent anticancer drug that is used in the treatment of a wide variety of cancerous. In the present study, we identified a taxol derivative named 7-epi-10-deacetyltaxol (EDT) from the culture of an endophytic fungus Pestalotiopsis microspora isolated from the bark of Taxodium mucronat...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-1993-8

    authors： Subban K,Singh S,Subramani R,Johnpaul M,Chelliah J

    更新日期：2017-11-28 00:00:00

  • Gene expression profiling reveals underlying molecular mechanism of hepatoprotective effect of Phyllanthus niruri on thioacetamide-induced hepatotoxicity in Sprague Dawley rats.

    abstract：BACKGROUND:The liver plays an essential role in the body by regulating several important metabolic functions. Liver injury is associated with the distortion of these functions causing many health problems. Pharmaceutical drugs treat liver disorders but cause further damage to it. Hence, herbal drugs are used worldwide ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-160

    authors： Amin ZA,Alshawsh MA,Kassim M,Ali HM,Abdulla MA

    更新日期：2013-07-05 00:00:00

  • Antifungal susceptibility and growth inhibitory response of oral Candida species to Brucea javanica Linn. extract.

    abstract：BACKGROUND:Candida species have been associated with the emergence of resistant strains towards selected antifungal agents. Plant products have been used traditionally as alternative medicine to ease candidal infections. The present study was undertaken to investigate the antifungal susceptibility patterns and growth i...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-342

    authors： Nordin MA,Wan Harun WH,Abdul Razak F

    更新日期：2013-12-04 00:00:00

  • Antioxidant and gastric cytoprotective prostaglandins properties of Cassia sieberiana roots bark extract as an anti-ulcerogenic agent.

    abstract：BACKGROUND:Cassia sieberiana is a savannah tree with a wide phytotherapeutic application including the use of its roots in the management of various stomach disorders including gastric ulcer, stomach pains and indigestion. The aim of the study is to evaluate the antioxidant, gastric cytoprotective prostaglandins, secre...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-12-65

    authors： Nartey ET,Ofosuhene M,Kudzi W,Agbale CM

    更新日期：2012-05-20 00:00:00

  • Anti-allodynic effect of intrathecal processed Aconitum jaluense is associated with the inhibition of microglial activation and P2X7 receptor expression in spinal cord.

    abstract：BACKGROUND:For their analgesic and anti-arthritic effects, Aconitum species have been used in folk medicine in some East Asian countries. Although their analgesic effect is attributed to its action on voltage-dependent sodium channels, they also suppress purinergic receptor expression in dorsal root ganglion neurons in...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1201-2

    authors： Yang J,Park KS,Yoon JJ,Bae HB,Yoon MH,Choi JI

    更新日期：2016-07-13 00:00:00

  • Ethyl acetate extract of germinated brown rice attenuates hydrogen peroxide-induced oxidative stress in human SH-SY5Y neuroblastoma cells: role of anti-apoptotic, pro-survival and antioxidant genes.

    abstract：BACKGROUND:There are reports of improved metabolic outcomes due to consumption of germinated brown rice (GBR). Many of the functional effects of GBR can be linked to its high amounts of antioxidants. Interestingly, dietary components with high antioxidants have shown promise in the prevention of neurodegenerative disea...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-177

    authors： Azmi NH,Ismail N,Imam MU,Ismail M

    更新日期：2013-07-17 00:00:00

  • Inhibitory effect of Yukmijihwang-tang, a traditional herbal formula against testosterone-induced benign prostatic hyperplasia in rats.

    abstract：BACKGROUND:Yukmijihwang-tang, a traditional herbal formula, has been used for treating disorder, diabetic mellitus and neurosis in China (Liu-wei-di-huang-tang in Chinese), Japan (Lokumijio-to in Japanese) and Korea for many years. In this study, we investigated the effects of Yukmijihwang-tang water extract (YJT) on t...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-12-48

    authors： Shin IS,Lee MY,Ha HK,Seo CS,Shin HK

    更新日期：2012-04-20 00:00:00

  • DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4.

    abstract：BACKGROUND:Chinese herbal formulae are composed of complex components and produce comprehensive pharmacological effects. Unlike chemical drugs that have only one clear single target, the components of Chinese herbal formulae have multiple channels and targets. How to discover the pharmacological targets of Chinese herb...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-14-67

    authors： Wang Y,Li C,Liu Z,Shi T,Wang Q,Li D,Wu Y,Han J,Guo S,Tang B,Wang W

    更新日期：2014-02-20 00:00:00

  • In vitro antitumor actions of extracts from endemic plant Helichrysum zivojinii.

    abstract：BACKGROUND:The aim of this research was to determine the intensity and mechanisms of the cytotoxic actions of five extracts isolated from the endemic plant species Helichrysum zivojinii Černjavski & Soška (family Asteraceae) against specific cancer cell lines. In order to evaluate the sensitivity of normal immunocompet...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-36

    authors： Matić IZ,Aljančić I,Žižak Ž,Vajs V,Jadranin M,Milosavljević S,Juranić ZD

    更新日期：2013-02-18 00:00:00