Kuramoto model simulation of neural hubs and dynamic synchrony in the human cerebral connectome.

abstract：BACKGROUND:Acute subdural hemorrhage (ASDH) is a severe consequence of traumatic brain injury. The occurrence of subdural blood increases the lethality of these patients independent of the amount of blood or elevated intracranial pressure. Thrombin is one of the potential harmful blood components. Possible harmful effe...

journal_title：BMC neuroscience

authors： Krämer TJ,Sakas W,Jussen D,Krenzlin H,Kempski O,Alessandri B

更新日期：2018-12-27 00:00:00

abstract：BACKGROUND:Adult neurogenesis continuously adds new neurons to the dentate gyrus and the olfactory bulb. It involves the proliferation and subsequent differentiation of neuronal progenitors, and is thus closely linked to the cell cycle machinery. Cell cycle progression is governed by the successive expression, activati...

journal_title：BMC neuroscience

authors： Ansorg A,Witte OW,Urbach A

更新日期：2012-05-07 00:00:00

abstract：BACKGROUND:To examine which language function depends on early experience, the present study compared deaf native signers, deaf non-native signers and hearing German native speakers while processing German sentences. The participants watched simple written sentences while event-related potentials (ERPs) were recorded. ...

journal_title：BMC neuroscience

authors： Skotara N,Salden U,Kügow M,Hänel-Faulhaber B,Röder B

更新日期：2012-05-03 00:00:00

abstract：BACKGROUND:Berberine is the major alkaloidal component of Rhizoma coptidis, and has multiple pharmacological effects including inhibiting acetylcholinesterase, reducing cholesterol and glucose, lowering mortality in patients with chronic congestive heart failure and anti-inflammation etc. Thus berberine is a promising ...

journal_title：BMC neuroscience

authors： Zhu F,Qian C

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Many studies of cerebral asymmetries in different species lead, on the one hand, to a better understanding of the functions of each cerebral hemisphere and, on the other hand, to develop an evolutionary history of hemispheric laterality. Our animal model is particularly interesting because of its original ev...

journal_title：BMC neuroscience

authors： Blois-Heulin C,Crével M,Böye M,Lemasson A

更新日期：2012-01-12 00:00:00

abstract：BACKGROUND:A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their ...

journal_title：BMC neuroscience

authors： Saito H,Dahlin LB

更新日期：2008-09-18 00:00:00

abstract：:Many studies have highlighted the pathological involvement of iron accumulation and iron-related oxidative stress (OS) in Alzheimer's disease (AD). Iron was further demonstrated to modulate expression of the Alzheimer's amyloid precursor holo-protein (APP) by a mechanism similar to that of regulation of ferritin-L and...

journal_title：BMC neuroscience

authors： Avramovich-Tirosh Y,Amit T,Bar-Am O,Weinreb O,Youdim MB

更新日期：2008-12-03 00:00:00

abstract：BACKGROUND:Understanding the underlying causes of nicotine addiction will require a multidisciplinary approach examining the key molecular, cellular and neuronal circuit functional changes that drive escalating levels of nicotine self-administration. In this study, we examined whether mice pretreated with chronic nicot...

journal_title：BMC neuroscience

authors： Renda A,Nashmi R

更新日期：2014-07-19 00:00:00

abstract：BACKGROUND:Anticipatory planning, the ability to anticipate future perceptual-motor demands of a goal-oriented action sequence, is essential for flexible, purposeful behavior. Once an action goal has been defined, movement details necessary to achieve that goal can be selected. Here, we investigate if anticipatory plan...

journal_title：BMC neuroscience

authors： Marangon M,Bucchioni G,Massacesi S,Castiello U

更新日期：2013-08-28 00:00:00

abstract：BACKGROUND:In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin remodeling as possible underlying mechanisms to explain chemotherapy-associat...

journal_title：BMC neuroscience

authors： Briones TL,Woods J

更新日期：2011-12-09 00:00:00

abstract：BACKGROUND:Parkinson's disease (PD) is a neurological disorder characterized by the degeneration of nigrostriatal dopaminergic systems. Free radicals induced by oxidative stress are involved in the mechanisms of cell death in PD. This study clarifies the neuroprotective effects of edaravone (MCI-186, 3-methyl-1-phenyl-...

journal_title：BMC neuroscience

authors： Yuan WJ,Yasuhara T,Shingo T,Muraoka K,Agari T,Kameda M,Uozumi T,Tajiri N,Morimoto T,Jing M,Baba T,Wang F,Leung H,Matsui T,Miyoshi Y,Date I

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:A recent study of lateral septum (LS) suggested a large number of autism-related genes with altered expression in the postpartum state. However, formally testing the findings for enrichment of autism-associated genes proved to be problematic with existing software. Many gene-disease association databases hav...

journal_title：BMC neuroscience

authors： Eisinger BE,Saul MC,Driessen TM,Gammie SC

更新日期：2013-11-19 00:00:00

abstract：BACKGROUND:One of the most basic human traits is language. Linguistic ability, and disability, have been shown to have a strong genetic component in family and twin studies, but molecular genetic studies of language phenotypes are scarce, relative to studies of other cognitive traits and neurodevelopmental phenotypes. ...

journal_title：BMC neuroscience

authors： Nudel R,Christiani CAJ,Ohland J,Uddin MJ,Hemager N,Ellersgaard D,Spang KS,Burton BK,Greve AN,Gantriis DL,Bybjerg-Grauholm J,Jepsen JRM,Thorup AAE,Mors O,Werge T,Nordentoft M

更新日期：2020-07-07 00:00:00

abstract：BACKGROUND:Excitatory transmitting mechanisms are proving to play a critical role on neuronal homeostasis conditions of facultative hibernators such as the Syrian golden hamster. Indeed works have shown that the glutamatergic system of the main olfactory brain station (amygdala) is capable of controlling thermoregulato...

journal_title：BMC neuroscience

authors： Alò R,Avolio E,Carelli A,Facciolo RM,Canonaco M

更新日期：2011-01-20 00:00:00

abstract：BACKGROUND:It has been reported that various types of axonal injury of hypothalamo-neurohypophyseal tract can result in degeneration of the magnocellular neurons (MCNs) in hypothalamus and development of central diabetes insipidus (CDI). However, the mechanism of the degeneration and death of MCNs after hypophysectomy ...

journal_title：BMC neuroscience

authors： Wang Y,Zhao C,Wang Z,Wang C,Feng W,Huang L,Zhang J,Qi S

更新日期：2008-06-25 00:00:00

abstract：BACKGROUND:Enhanced activity of trigeminal ganglion neurons is thought to underlie neuronal sensitization facilitating the onset of chronic pain attacks, including migraine. Recurrent headache attacks might establish a chronic neuroinflammatory ganglion profile contributing to the hypersensitive phenotype. Since it is ...

journal_title：BMC neuroscience

authors： Franceschini A,Nair A,Bele T,van den Maagdenberg AM,Nistri A,Fabbretti E

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:Protein aggregation plays important roles in several neurodegenerative disorders. For instance, insoluble aggregates of phosphorylated tau and of Aβ peptides are cornerstones in the pathology of Alzheimer's disease. Soluble protein aggregates are therefore potential diagnostic and prognostic biomarkers for t...

journal_title：BMC neuroscience

authors： Kamali-Moghaddam M,Pettersson FE,Wu D,Englund H,Darmanis S,Lord A,Tavoosidana G,Sehlin D,Gustafsdottir S,Nilsson LN,Lannfelt L,Landegren U

更新日期：2010-10-05 00:00:00

abstract：BACKGROUND:Imprinting behavior is one form of learning and memory in precocial birds. With the aim of elucidating of the neural basis for visual imprinting, we focused on visual information processing. RESULTS:A lesion in the visual wulst, which is similar functionally to the mammalian visual cortex, caused anterograd...

journal_title：BMC neuroscience

authors： Maekawa F,Komine O,Sato K,Kanamatsu T,Uchimura M,Tanaka K,Ohki-Hamazaki H

更新日期：2006-11-14 00:00:00

abstract：BACKGROUND:In the absence of overt stimuli, the brain shows correlated fluctuations in functionally related brain regions. Approximately ten largely independent resting state networks (RSNs) showing this behaviour have been documented to date. Recent studies have reported the existence of an RSN in the basal ganglia - ...

journal_title：BMC neuroscience

authors： Robinson S,Basso G,Soldati N,Sailer U,Jovicich J,Bruzzone L,Kryspin-Exner I,Bauer H,Moser E

更新日期：2009-11-23 00:00:00

abstract：BACKGROUND:Opioid agonist drugs produce analgesia. However, long-term exposure to opioid agonists may lead to opioid dependence. The analgesic and addictive properties of opioid agonist drugs are mediated primarily via the mu-opioid receptor (MOR). Opioid agonists appear to alter neuronal morphology in key brain region...

journal_title：BMC neuroscience

authors： Jin J,Kittanakom S,Wong V,Reyes BA,Van Bockstaele EJ,Stagljar I,Berrettini W,Levenson R

更新日期：2010-03-09 00:00:00

abstract：BACKGROUND:Humans demonstrate a number of unique adaptations that allow for the maintenance of blood pressure and brain blood flow when upright. While several physiological systems, including cerebral autoregulation, are involved in this adaptation the unique role the vestibular system plays in helping to maintain brai...

journal_title：BMC neuroscience

authors： Serrador JM,Schlegel TT,Black FO,Wood SJ

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:Better treatments for schizophrenia are urgently needed. The therapeutic use of the nitric oxide (NO)-donor sodium nitroprusside (SNP) in patients with schizophrenia has shown promising results. The role of NO in schizophrenia is still unclear, and NO modulation is unexplored in ketamine (KET) animal models ...

journal_title：BMC neuroscience

authors： Kandratavicius L,Balista PA,Wolf DC,Abrao J,Evora PR,Rodrigues AJ,Chaves C,Maia-de-Oliveira JP,Leite JP,Dursun SM,Baker GB,Guimaraes FS,Hallak JE

更新日期：2015-03-07 00:00:00

abstract：BACKGROUND:Fetal asphyctic (FA) preconditioning is effective in attenuating brain damage incurred by a subsequent perinatal asphyctic insult. Unraveling mechanisms of this endogenous neuroprotection, activated by FA preconditioning, is an important step towards new clinical strategies for asphyctic neonates. Genomic re...

journal_title：BMC neuroscience

authors： Cox-Limpens KE,Vles JS,Schlechter J,Zimmermann LJ,Strackx E,Gavilanes AW

更新日期：2013-06-22 00:00:00

abstract：BACKGROUND:Yawning is a stereotyped behavior that enhances blood flow to the skull, and the resulting counterflow has been hypothesized as a mechanism for brain cooling. Studies have shown that yawns are strongly associated with physiological and pathological conditions that increase brain temperature, and that they ar...

journal_title：BMC neuroscience

authors： Eguibar JR,Uribe CA,Cortes C,Bautista A,Gallup AC

更新日期：2017-01-03 00:00:00

abstract：BACKGROUND:Several studies have shown that Stroop interference is stronger in children than in adults. However, in a standard Stroop paradigm, stimulus interference and response interference are confounded. The purpose of the present study was to determine whether interference at the stimulus level and the response lev...

journal_title：BMC neuroscience

authors： Jongen EM,Jonkman LM

更新日期：2008-09-05 00:00:00

abstract：BACKGROUND:To reach and grasp an object in space on the basis of its image cast on the retina requires different coordinate transformations that take into account gaze and limb positioning. Eye position in the orbit influences the image's conversion from retinotopic (eye-centered) coordinates to an egocentric frame nec...

journal_title：BMC neuroscience

authors： Andersson F,Etard O,Denise P,Petit L

更新日期：2004-09-19 00:00:00

abstract：BACKGROUND:The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments. In the present study we performed a systematic characterization of the spatio-temporal patterns of S- and...

journal_title：BMC neuroscience

authors： Narayan DS,Ao J,Wood JPM,Casson RJ,Chidlow G

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Human neural stem cells (hNSC) have the potential to provide novel cell-based therapies for neurodegenerative conditions such as multiple sclerosis and Parkinson's disease. In order to realise this goal, protocols need to be developed that allow for large quantities of hNSC to be cultured efficiently. As suc...

journal_title：BMC neuroscience

authors： Hall PE,Lathia JD,Caldwell MA,Ffrench-Constant C

更新日期：2008-07-23 00:00:00

abstract：BACKGROUND:Low-intensity pulsed ultrasound stimulation (LIPUS) has been proven to be a noninvasive method with high spatial resolution and deep penetration. Previous studies have qualitatively demonstrated that the electromyographic response caused by LIPUS in the mouse motor cortex is affected by the anesthetic state ...

journal_title：BMC neuroscience

authors： Yuan Y,Wang X,Yan J,Li X

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:Functional magnetic resonance imaging (fMRI) in white matter has long been considered controversial. Recently, this viewpoint has been challenged by an emerging body of evidence demonstrating white matter activation in the corpus callosum. The current study aimed to determine whether white matter activation ...

journal_title：BMC neuroscience

authors： Gawryluk JR,Mazerolle EL,Brewer KD,Beyea SD,D'Arcy RC

更新日期：2011-06-14 00:00:00