Incidence of gastric cancer among patients with gastric precancerous lesions: observational cohort study in a low risk Western population.

abstract：OBJECTIVE:To assess the effects of Helicobacter pylori treatment, vitamin supplementation, and garlic supplementation in the prevention of gastric cancer. DESIGN:Blinded randomized placebo controlled trial. SETTING:Linqu County, Shandong province, China. PARTICIPANTS:3365 residents of a high risk region for gastric ...

journal_title：BMJ (Clinical research ed.)

authors： Li WQ,Zhang JY,Ma JL,Li ZX,Zhang L,Zhang Y,Guo Y,Zhou T,Li JY,Shen L,Liu WD,Han ZX,Blot WJ,Gail MH,Pan KF,You WC

更新日期：2019-09-11 00:00:00

abstract：OBJECTIVE:To evaluate the effects of a multifaceted empowerment strategy on the actual use of single embryo transfer after in vitro fertilisation. DESIGN:Randomised controlled trial. SETTING:Five in vitro fertilisation clinics in the Netherlands. PARTICIPANTS:308 couples (women aged <40) on the waiting list for a fi...

journal_title：BMJ (Clinical research ed.)

authors： van Peperstraten A,Nelen W,Grol R,Zielhuis G,Adang E,Stalmeier P,Hermens R,Kremer J

更新日期：2010-09-30 00:00:00

abstract：:The numbers of patients being admitted to hospital with aortic aneurysms have increased recently. A study was carried out to try to find out whether this was a true increase in incidence or whether it could be attributable to more accurate diagnosis and better surgical techniques. From analyses of routine statistics i...

journal_title：BMJ (Clinical research ed.)

authors： Fowkes FG,Macintyre CC,Ruckley CV

更新日期：1989-01-07 00:00:00

abstract：:Objective To estimate the incidence and prevalence of resistant hypertension among a UK population treated for hypertension from 1995 to 2015.Design Cohort study.Setting Electronic health records from the UK Clinical Practice Research Datalink in primary care.Participants 1 317 290 users of antihypertensive drugs with...

journal_title：BMJ (Clinical research ed.)

authors： Sinnott SJ,Smeeth L,Williamson E,Douglas IJ

更新日期：2017-09-22 00:00:00

abstract：:The disease management approach to patient care seeks to coordinate resources across the healthcare delivery system. The growing interest in evidence based medicine and outcomes, and a commitment to integrated care across the primary, secondary, and community care sectors, all contribute to making disease management a...

journal_title：BMJ (Clinical research ed.)

authors： Hunter DJ,Fairfield G

更新日期：1997-07-05 00:00:00

abstract：OBJECTIVE:To describe risk factors for infantile colic. DESIGN:Questionnaire administered by health visitors. SETTING:Sheffield. SUBJECTS:Mothers of 76,747 infants born between 1 August 1975 and 31 May 1988, interviewed when the infant was 1 month old. MAIN OUTCOME MEASURES:Reporting of infantile colic and its dura...

journal_title：BMJ (Clinical research ed.)

authors： Crowcroft NS,Strachan DP

更新日期：1997-05-03 00:00:00

abstract：:A study was carried out analysing the operation of a drug rationalisation programme in a central London teaching district that had evolved from experience over 17 years. Creation of a limited list of about 700 drugs had been achieved by local consensus. Drug selection was based on appraisal of efficacy, safety, and co...

journal_title：BMJ (Clinical research ed.)

authors： Baker JA,Lant AF,Sutters CA

更新日期：1988-08-13 00:00:00

abstract：OBJECTIVE:To determine the effect of combinations of statins, aspirin, beta blockers, and angiotensin converting enzyme inhibitors in the secondary prevention of all cause mortality in patients with ischaemic heart disease. DESIGN:Open prospective cohort study with nested case-control analysis. SETTING:1.18 million p...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Coupland C

更新日期：2005-05-07 00:00:00

abstract：OBJECTIVE:To describe the mechanism established by Richmond, Twickenham, and Roehampton Health Authority to manage extracontractual referral requests made on behalf of its resident population and to examine its working in the first three months of the new arrangements. DESIGN:Description of the procedures for managing...

journal_title：BMJ (Clinical research ed.)

authors： Williamson JD

更新日期：1991-08-31 00:00:00

abstract：:Since the World Health Organization (WHO) set a goal in 1988 of eradicating polio worldwide by 2000, the incidence of the disease has declined by 90% around the world, with national immunization days conducted in more than 120 countries. More than 450 million children were immunized in 1998 alone. Now, with only abo...

journal_title：BMJ (Clinical research ed.)

authors： Mach A

更新日期：1999-03-20 00:00:00

abstract：:This paper summarizes the key findings of a U.S. study of 48 primary care physicians acting as gatekeepers in a large health maintenance organization to determine the effects of their cost containment role on the doctor patient relationship. Taylor highlights some of the findings and conclusions that he believes are ...

journal_title：BMJ (Clinical research ed.)

authors： Taylor TR

更新日期：1989-11-25 00:00:00

abstract：OBJECTIVES:To assess the incidence, time of day, and driver morbidity associated with vehicle accidents where the most likely cause was the driver falling asleep at the wheel. DESIGN:Two surveys were undertaken, in southwest England and the midlands, by using police databases or on the spot interviews. SUBJECTS:Drive...

journal_title：BMJ (Clinical research ed.)

authors： Horne JA,Reyner LA

更新日期：1995-03-04 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00

abstract：OBJECTIVES:To compare patients' preference for transdermal fentanyl or sustained release oral morphine, their level of pain control, and their quality of life after treatment. DESIGN:Randomised, multicentre, international, open label, crossover trial. SETTING:35 centres in Belgium, Canada, Denmark, Finland, the Unite...

journal_title：BMJ (Clinical research ed.)

authors： Allan L,Hays H,Jensen NH,de Waroux BL,Bolt M,Donald R,Kalso E

更新日期：2001-05-12 00:00:00

abstract：OBJECTIVE: To determine whether the treatment effect of apixaban versus warfarin differs with increasing numbers of concomitant drugs used by patients with atrial fibrillation. DESIGN: Post hoc analysis performed in 2015 of results from ARISTOTLE (apixaban for reduction in stroke and other thromboembolic events in atr...

journal_title：BMJ (Clinical research ed.)

authors： Jaspers Focks J,Brouwer MA,Wojdyla DM,Thomas L,Lopes RD,Washam JB,Lanas F,Xavier D,Husted S,Wallentin L,Alexander JH,Granger CB,Verheugt FW

更新日期：2016-06-15 00:00:00

abstract：:The high prevalence of cigarette smoking and tobacco related morbidity and mortality in people with chronic mental illness is well documented. This review summarizes results from studies of smoking cessation treatments in people with schizophrenia, depression, anxiety disorders, and post-traumatic stress disorder. It ...

journal_title：BMJ (Clinical research ed.)

authors： Tidey JW,Miller ME

更新日期：2015-09-21 00:00:00

abstract：OBJECTIVE:To assess the implementation of action protocols dictated by antenatal risk factors noted at the initial (booking) antenatal visit. DESIGN:Retrospective study of 2000 women delivered between 1 March 1990 and 29 March 1991. SETTING:Maternity department of a district general hospital supporting a multiethnic ...

journal_title：BMJ (Clinical research ed.)

authors： Yoong AF,Lim J,Hudson CN,Chard T

更新日期：1992-11-14 00:00:00

abstract：OBJECTIVES:To assess the association of Apgar score 5 minutes after birth with cerebral palsy in both normal weight and low birthweight children, and also the association with the cerebral palsy subdiagnoses of quadriplegia, diplegia, and hemiplegia. DESIGN:Population based cohort study. SETTING:The Medical Birth Reg...

journal_title：BMJ (Clinical research ed.)

authors： Lie KK,Grøholt EK,Eskild A

更新日期：2010-10-06 00:00:00

abstract：PROBLEM:Deep infection after joint arthroplasty can be catastrophic, leading to further surgery, loss of the prosthesis, disability, and risk of mortality. Twenty nine new cases of methicillin resistant Staphylococcus aureus occurred in the first year after elective orthopaedic surgery was centralised to a district gen...

journal_title：BMJ (Clinical research ed.)

authors： Biant LC,Teare EL,Williams WW,Tuite JD

更新日期：2004-07-17 00:00:00

abstract：OBJECTIVES:To measure the potential for cadaver organ retrieval in New South Wales and to determine the reasons for potential donors failing to become actual donors. DESIGN:Prospective audit of all patients dying in five hospitals in New South Wales between 1 December 1989 and 30 November 1990; quality assurance of th...

journal_title：BMJ (Clinical research ed.)

authors： Hibberd AD,Pearson IY,McCosker CJ,Chapman JR,Macdonald GJ,Thompson JF,O'Connell DL,Mohacsi PJ,McLoughlin MP,Spratt PM

更新日期：1992-05-23 00:00:00

abstract：OBJECTIVE:To assess the potential effects of primary prevention with anticoagulants or aspirin in atrial fibrillation on Swedish population. DESIGN:Analysis of cost effectiveness based on the following assumptions: about 83,000 people have atrial fibrillation in Sweden, of whom 22,000 would be potential candidates for...

journal_title：BMJ (Clinical research ed.)

authors： Gustafsson C,Asplund K,Britton M,Norrving B,Olsson B,Marké LA

更新日期：1992-12-12 00:00:00

abstract：OBJECTIVE:To design and evaluate a computer advisory system for the treatment of gestational trophoblastic tumour. DESIGN:A comparison of clinicians' treatment decisions with those of the computer system. Two datasets were used: one to calibrate the system and one to independently evaluate it. SETTING:Department of m...

journal_title：BMJ (Clinical research ed.)

authors： Leaning MS,Gallivan S,Newlands ES,Dent J,Brampton M,Smith DB,Bagshawe KD

更新日期：1992-10-03 00:00:00

abstract：:Objective To estimate the cumulative radiation exposure and lifetime attributable risk of cancer incidence associated with lung cancer screening using annual low dose computed tomography (CT).Design Secondary analysis of data from a lung cancer screening trial and risk-benefit analysis.Setting 10 year, non-randomised,...

journal_title：BMJ (Clinical research ed.)

authors： Rampinelli C,De Marco P,Origgi D,Maisonneuve P,Casiraghi M,Veronesi G,Spaggiari L,Bellomi M

更新日期：2017-02-08 00:00:00

abstract：OBJECTIVE:To test whether a drug review and symptom self management and lifestyle advice intervention by community pharmacists could reduce hospital admissions or mortality in heart failure patients. DESIGN:Randomised controlled trial. SETTING:Home based intervention in heart failure patients. PARTICIPANTS:293 patie...

journal_title：BMJ (Clinical research ed.)

authors： Holland R,Brooksby I,Lenaghan E,Ashton K,Hay L,Smith R,Shepstone L,Lipp A,Daly C,Howe A,Hall R,Harvey I

更新日期：2007-05-26 00:00:00

abstract：OBJECTIVE:To assess the association between genotype at the insertion or deletion polymorphism of the angiotensin converting enzyme gene and risk of coronary restenosis after percutaneous coronary intervention. DESIGN:Meta-analysis of studies before July 2001 that reported on these genotypes and risk of coronary reste...

journal_title：BMJ (Clinical research ed.)

authors： Bonnici F,Keavney B,Collins R,Danesh J

更新日期：2002-09-07 00:00:00

abstract：OBJECTIVE:To examine the associations between neuraxial anaesthesia or general anaesthesia and clinical outcomes, length of hospital stay, and readmission in adults undergoing lower limb revascularisation surgery. DESIGN:Comparative effectiveness study using linked, validated, population based databases. SETTING:Onta...

journal_title：BMJ (Clinical research ed.)

authors： Roberts DJ,Nagpal SK,Kubelik D,Brandys T,Stelfox HT,Lalu MM,Forster AJ,McCartney CJ,McIsaac DI

更新日期：2020-11-25 00:00:00

abstract：OBJECTIVES:To determine the effectiveness of tai chi interventions compared with aerobic exercise, a current core standard treatment in patients with fibromyalgia, and to test whether the effectiveness of tai chi depends on its dosage or duration. DESIGN:Prospective, randomized, 52 week, single blind comparative effec...

journal_title：BMJ (Clinical research ed.)

authors： Wang C,Schmid CH,Fielding RA,Harvey WF,Reid KF,Price LL,Driban JB,Kalish R,Rones R,McAlindon T

更新日期：2018-03-21 00:00:00

abstract：OBJECTIVE:To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the intervention or outcome. DESIGN:Combined analysis of data from three meta-epidemiological studies based on collections of meta-an...

journal_title：BMJ (Clinical research ed.)

authors： Wood L,Egger M,Gluud LL,Schulz KF,Jüni P,Altman DG,Gluud C,Martin RM,Wood AJ,Sterne JA

更新日期：2008-03-15 00:00:00

abstract：:An increase in the incidence of cardiovascular disease has generally been observed in postmenopausal women, but there have been few studies of the association between menopausal state and atherosclerosis. In this study 294 premenopausal and 319 postmenopausal women aged 45 to 55 were examined radiographically for calc...

journal_title：BMJ (Clinical research ed.)

authors： Witteman JC,Grobbee DE,Kok FJ,Hofman A,Valkenburg HA

更新日期：1989-03-11 00:00:00

abstract：OBJECTIVE:To assess the risk of epileptic seizures in people with and without epilepsy after vaccination with a monovalent AS03 adjuvanted pandemic A/H1N1 influenza vaccine (Pandemrix; Glaxo SmithKline, Sweden). DESIGN:Register based self controlled case series. SETTING:Three Swedish counties (source population 750,0...

journal_title：BMJ (Clinical research ed.)

authors： Arnheim-Dahlström L,Hällgren J,Weibull CE,Sparén P

更新日期：2012-12-18 00:00:00