Abstract:
BACKGROUND:Dual imaging stress echocardiography, combining the evaluation of wall motion and coronary flow reserve (CFR) on the left anterior descending artery (LAD), and computed tomography coronary angiography (CTCA) are established techniques for assessing prognosis in chest pain patients. In this study we compared the prognostic value of the two methods in a cohort of patients with chest pain having suspected coronary artery disease (CAD). METHODS:A total of 131 patients (76 men; age 68 ± 9 years) with chest pain of unknown origin underwent dipyridamole (up to 0.84 mg/kg over 6 min) stress echo with CFR assessment of LAD by Doppler and CTCA. A CFR ≤ 1.9 was considered abnormal, while > 50% lumen diameter reduction was the criterion for significant CAD at CTCA. RESULTS:Of 131 patients, 34 (26%) had ischemia at stress echo (new wall motion abnormalities), and 56 (43%) had reduced CFR on LAD. Significant coronary stenosis at CTCA was found in 69 (53%) patients. Forty-six patients (84%) with abnormal CFR on LAD showed significant CAD at CTCA (p < 0.001). Calcium score was higher in patients with reduced than in those with normal CFR (265 ± 404 vs 131 ± 336, p = 0.04). During a median follow-up of 7 months (1st to 3rd quartile: 5-13 months), there were 45 major cardiac events (4 deaths, 11 nonfatal myocardial infarctions, and 30 late [≥6 months] coronary revascularizations). At Cox analysis, independent prognostic indicators were calcium score > 100 (HR 2.84, 95% CI 1.33-6.07, p = 0.007), significant CAD at CTCA (HR 2.68, 95% CI 1.23-5.82, p = 0.013), and inducible ischemia or CFR <1.9R on LAD on dual imaging stress echo (HR 2.25, 95% CI 1.05-4.84, p = 0.038). CONCLUSIONS:Functional and anatomical evaluation using, respectively, dual imaging stress echocardiography and CTCA are both effective modalities to risk stratify patients with chest pain of unknown origin, yielding independent and comparable prognostic value. Compared to CTCA, however, stress echocardiography has the advantage of lower cost and of being free of radiations.
journal_name
Cardiovasc Ultrasoundjournal_title
Cardiovascular ultrasoundauthors
Ciampi Q,Rigo F,Grolla E,Picano E,Cortigiani Ldoi
10.1186/s12947-015-0013-8subject
Has Abstractpub_date
2015-04-21 00:00:00pages
21issn
1476-7120pii
10.1186/s12947-015-0013-8journal_volume
13pub_type
杂志文章abstract:BACKGROUND:Though hemodialysis (HD) acutely improves cardiac function, the impact of background diseases like coronary artery disease (CAD) and Type 2 diabetes (DM) in the setting of end-stage renal disease (ESRD) is not known. Tissue velocity echocardiography (TVE) offers a fast choice to follow changes in myocardial ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-4-9
更新日期:2006-02-02 00:00:00
abstract:BACKGROUND:While echocardiographic grading of left ventricular (LV) diastolic dysfunction (DD) is used every day, the relationship between echocardiographic DD grade and hemodynamic abnormalities is uncertain. METHODS:We identified 460 consecutive patients who underwent transthoracic echocardiography within 24 h of el...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-015-0023-6
更新日期:2015-06-24 00:00:00
abstract:BACKGROUND:The goal of this study was to determine if left ventricular (LV) global longitudinal strain (GLS) predicts heart failure (HF) readmission in patients with acute decompensated heart failure. METHODS AND RESULTS:Two hundred ninety one patients were enrolled at the time of admission for acute decompensated hea...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-017-0098-3
更新日期:2017-03-15 00:00:00
abstract:BACKGROUND:Theoretically, a cross-sectional image of any cardiac planes can be obtained from a STIC fetal heart volume dataset. We described a method to display 11 fetal echocardiographic planes from STIC volumes. METHODS:Fetal heart volume datasets were acquired by transverse acquisition from 200 normal fetuses at 15...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-8-41
更新日期:2010-09-15 00:00:00
abstract::In the standard accepted concept, contractility is the intrinsic ability of heart muscle to generate force and to shorten, independently of changes in the preload or afterload with fixed heart rates. At molecular level the crux of the contractile process lies in the changing concentrations of Ca2+ ions in the myocardi...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章,评审
doi:10.1186/1476-7120-3-27
更新日期:2005-09-08 00:00:00
abstract:OBJECTIVE:Left ventricular wall stress has been investigated in a variety of populations, but the effect of food intake has not been evaluated. We assessed whether left ventricular wall stress is affected by food intake in healthy subjects. METHODS:Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated....
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-12-2
更新日期:2014-01-28 00:00:00
abstract:BACKGROUND:Use of preoperative echocardiography may help to identify patients with increased cardiac risk, who may benefit from modification of perioperative plan. The objective of our study was to evaluate the reliability of preoperative focused cardiac ultrasound (FoCUS) performed by an anaesthetist with basic ultras...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-015-0039-y
更新日期:2015-11-20 00:00:00
abstract:BACKGROUND:Aortic valve stenosis (AS) is the most common primary valvular heart disease leading to surgical or percutaneous aortic valve replacement (AVR) in Europe and its prevalence keeps growing. While other risk factors in severe AS are well documented, little is known about the prognostic value of left atrial (LA)...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-020-00231-0
更新日期:2021-01-02 00:00:00
abstract:BACKGROUND:The association of a Classical left bundle branch block (LBBB) contraction pattern and better outcome after cardiac resynchronization therapy (CRT) has only been studied using vendor-specific software for echocardiographic speckle-tracked longitudinal strain analysis. The purpose of this study was to assess ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0160-4
更新日期:2019-05-21 00:00:00
abstract:INTRODUCTION:Serial monitoring of patients participating in clinical trials of carotid artery therapy requires noninvasive precision methods that are inexpensive, safe and widely available. Noninvasive ultrasonic duplex Doppler velocimetry provides a precision method that can be used for recruitment qualification, pre-...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-8-39
更新日期:2010-09-07 00:00:00
abstract::The growing need for coronary evaluation has raised interest in non-radioactive, non-invasive monitoring systems. In particular, radiation exposure during coronary investigations has been shown to be a possible cause of an enhanced risk of secondary tumors. Literature search has indicated that transthoracic echocardio...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章,评审
doi:10.1186/s12947-016-0048-5
更新日期:2016-01-19 00:00:00
abstract::Originally described by Brock and Teare, today hypertrophic cardiomyopathy is clinically defined as left (or right) ventricular hypertrophy without a known cardiac or systemic cause, such as systemic hypertension, Fabry's disease or aortic stenosis.Also appreciated today is the enormous genotypic and phenotypic hetero...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-7-31
更新日期:2009-07-03 00:00:00
abstract::To make assessment of paravalvular aortic leakage (PVL) after transcatheter aortic valve implantation (TAVI) more uniform the second Valve Academic Research Consortium (VARC) recently updated the echocardiographic criteria for mild, moderate and severe PVL. In the VARC recommendation the assessment of the circumferent...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章,评审
doi:10.1186/s12947-016-0080-5
更新日期:2016-09-06 00:00:00
abstract:BACKGROUND:In patients with advanced non-ischemic cardiomyopathy (NIC), right-sided cardiac disturbances has prognostic implications. Right coronary artery (RCA) flow pattern and flow reserve (CFR) are not well known in this setting. The purpose of this study was to assess, in human advanced NIC, the RCA phasic flow pa...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-5-31
更新日期:2007-09-26 00:00:00
abstract:BACKGROUND:Systemic sclerosis (SSc) is an autoimmune chronic disease characterized by diffuse fibrosis involving several organs, including heart. Aim of our study was to analyze left ventricular (LV) myocardial deformation, by use of 2D strain, in asymptomatic SSc patients with normal LV ejection fraction. METHODS:We ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-11-6
更新日期:2013-02-03 00:00:00
abstract::Miniaturization has evolved in the creation of a pocket-size imaging device which can be utilized as an ultrasound stethoscope. This study assessed the additional diagnostic power of pocket size device by both experts operators and trainees in comparison with physical examination and its appropriateness of use in comp...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-8-51
更新日期:2010-11-26 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV) infection and antiretroviral treatment are associated with metabolic and cardiovascular complications that potentially increase the risk of atherosclerosis and cardiovascular disease in this population. Measurement of arterial wall thickness has been used as a surrogate of ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-9-9
更新日期:2011-04-01 00:00:00
abstract:AIMS:We sought to determine which echocardiographic markers of left ventricular (LV) remodeling and diastolic dysfunction can contribute as incremental and independent prognostic information in addition to current clinical risk markers of ischemic LV systolic dysfunction in the Surgical Treatment for Ischemic Heart Fai...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-020-00195-1
更新日期:2020-05-28 00:00:00
abstract:BACKGROUND:Left ventricular (LV) ejection fraction (LVEF) assessed by two-dimensional echocardiography (2DE) is the most widely used parameter for clinical decision-making, but reproducibility and accuracy problems remain. We evaluated the usefulness of a novel training program based on cardiac magnetic resonance (CMR)...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0173-z
更新日期:2019-10-31 00:00:00
abstract:PURPOSE:Left ventricular (LV) wall thickness can be measured at the posterior wall (PW) and the intraventricular septum (IVS) in a parasternal long axis view by transthoracic echocardiography. Thus, there are three methods to calculate relative wall thickness as follows: RWTPW = 2 × PWth/LVDd; RWTIVS + PW = (IVSth + PW...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0179-6
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:Almost all attempts to improve patient selection for cardiac resynchronization therapy (CRT) using echo-derived indices have failed so far. We sought to assess: the performance of homemade software for the automatic quantification of integral 3D regional longitudinal strain curves exploring left ventricular ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-017-0107-6
更新日期:2017-06-17 00:00:00
abstract:BACKGROUND:We hypothesized that longitudinal pulmonary arterial deformation during the cardiac cycle reflects pulmonary arterial capacitance. To examine this hypothesis, we assessed whether tissue Doppler-derived pulmonary annular motion could serve as a novel way to evaluate pulmonary arterial capacitance in pediatric...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-016-0081-4
更新日期:2016-09-07 00:00:00
abstract:BACKGROUND:Myocardial deformation imaging using speckle-tracking echocardiography to assess global longitudinal strain (GLS) is today considered a more sensitive measure of left ventricular (LV) systolic function than ejection fraction. General anesthesia and positive pressure ventilation (PPV) are known to change the ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0165-z
更新日期:2019-08-10 00:00:00
abstract:INTRODUCTION:In vivo and in vitro evidence suggests that adenosine and its agonists play key roles in the process of ischemic preconditioning. The effects of low-dose adenosine infusion on ischemic preconditioning have not been thoroughly studied in humans. AIMS:We hypothesised that a low-dose adenosine infusion could...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章,随机对照试验
doi:10.1186/1476-7120-7-52
更新日期:2009-11-05 00:00:00
abstract:BACKGROUND:Atrial septal defect (ASD) accounts for 10% of all congenital heart lesions and represent the third most congenital cardiac defect seen in adults. Atrial natriuretic peptide (ANP) is an important regulator of the sodium and volume homeostasis. This study was designed to investigate the changes in plasma ANP ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-6-35
更新日期:2008-07-07 00:00:00
abstract:BACKGROUND:Fetal anemia is associated with a hyperdynamic circulation and cardiac remodeling. Rapid intrauterine transfusion (IUT) of blood with high hematocrit and viscosity into the umbilical vein used to treat this condition can temporarily further affect fetal heart function. The aim of this study was to evaluate t...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-020-00214-1
更新日期:2020-08-13 00:00:00
abstract::In this case report we describe a rare case of right atrium myxoma that coexisted with antiphospholipid syndrome in a young woman. We describe the unusual findings and diagnostic challenges combined with a review of the literature. ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-7-47
更新日期:2009-10-11 00:00:00
abstract:BACKGROUND:Primary intracardiac tumours are rare, there are however several entities that can mimic tumours. Contrast echocardiography has been suggested to aid the differentiation of various suspected masses. We present a case where transthoracic echocardiography completely misdiagnosed a left atrial mass, partly due ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-7-4
更新日期:2009-01-29 00:00:00
abstract:BACKGROUND:The contractile response of patients with heart failure (HF) may be assessed by exercise stress echocardiography (ESE)-derived indexes. We sought to test whether ESE parameters are useful to identify the risk of adverse left ventricular (LV) remodeling in patients with chronic HF and reduced or mildly reduce...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0157-z
更新日期:2019-04-06 00:00:00
abstract:BACKGROUND:Myocardial contractility can be investigated using longitudinal peak strain. It can be calculated using the Doppler-derived TDI method and the non-Doppler method based on tissue tracking on B-mode images. Both are validated and show good reproducibility, but no comparative analysis of their results has yet b...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-5-7
更新日期:2007-02-07 00:00:00