Effects of electroacupuncture on recovery of the electrophysiological properties of the rabbit gastrocnemius after contusion: an in vivo animal study.

Abstract:

BACKGROUND:Our preliminary studies indicated that electroacupuncture (EA) at the ST36 and Ashi acupoints could promote regeneration of the rabbit gastrocnemius (GM) by improving microcirculation perfusion, promoting the recovery of myofiber structures, and inhibiting excessive fibrosis. However, the effects of EA on recovery of the electrophysiological properties of the GM after contusion are not yet clear. Thus, the purpose of this study was to investigate the effects of EA at the Zusanli (ST36) and Ashi acupoints with regard to recovery of the electrophysiological properties of the rabbit GM after contusion. METHODS:Forty-five rabbits were randomly divided into three groups: normal, contusion, and EA. After an acute GM contusion was produced (in rabbits in the contusion and EA groups), rabbits in the EA group were treated with electrostimulation at the ST36 and Ashi acupoints with 0.4 mA (2 Hz) for 15 min. The contusion group received no EA treatment. At different time points (7, 14, and 28 days) after contusion, we performed surface electromyography (EMG) and measured the nerve conduction velocity (NCV) of the GM and the GM branch of the tibial nerve. We also examined acetylcholinesterase (AchE) and Agrin expression in the neuromuscular junction (NMJ) via immunohistochemistry. RESULTS:Compared with the contusion group, the EMG amplitude and NCV in rabbits in the EA group were significantly higher at all time points after contusion. AchE and Agrin expression in the EA group were significantly higher than those in the contusion group. CONCLUSIONS:Our results showed that EA at the ST36 and Ashi acupoints effectively promoted recovery of the electrophysiological properties of the rabbit GM after contusion. The effects of EA were realized by promotion of the regeneration of myofibers and nerve fibers, as well as acceleration of NMJ reconstruction by upregulation of AchE and Agrin expression in the motor endplate area.

authors

Liu S,Wang R,Luo D,Xu Q,Xiao C,Lin P,Yu Z,Zhao X,Cai R,Ma J,Zhang Q,Wang Y

doi

10.1186/s12906-015-0601-z

subject

Has Abstract

pub_date

2015-03-19 00:00:00

pages

69

issn

1472-6882

pii

10.1186/s12906-015-0601-z

journal_volume

15

pub_type

杂志文章
  • The ameliorating effects of long-term electroacupuncture on cardiovascular remodeling in spontaneously hypertensive rats.

    abstract:BACKGROUND:The purpose of this study was to investigate the inhibitory effects of long-term electroacupuncture at BaiHui (DU20) and ZuSanLi (ST36) on cardiovascular remodeling in spontaneously hypertensive rats (SHR) and underlying mechanisms. METHODS:6-weeks-old SHR or Wistar male rats were randomly, divided into 6 g...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-118

    authors: Huo ZJ,Li Q,Tian GH,Zhou CM,Wei XH,Pan CS,Yang L,Bai Y,Zhang YY,He K,Wang CS,Li ZG,Han JY

    更新日期:2014-04-01 00:00:00

  • Anti-hepatotoxic activities of Hibiscus sabdariffa L. in animal model of streptozotocin diabetes-induced liver damage.

    abstract:BACKGROUND:Flavonoid-rich aqueous fraction of methanolic extract of Hibiscus sabdariffa calyx was evaluated for its anti-hepatotoxic activities in streptozotocin-induced diabetic Wistar rats. METHODS:Diabetes Mellitus was induced in Wistar rats by a single i.p injection of 80 mg/kg b.w. streptozotocin (STZ) dissolved ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-277

    authors: Adeyemi DO,Ukwenya VO,Obuotor EM,Adewole SO

    更新日期:2014-07-30 00:00:00

  • Toxicological studies of stem bark extract from Schefflera barteri Harms (Araliaceae).

    abstract:BACKGROUND:The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barteri is popularly used in the West region of Cameroon for the treatment of various diseases such as ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-015-0581-z

    authors: Atsafack SS,Kuiate JR,Mouokeu RS,Koanga Mogtomo ML,Tchinda AT,De Dieu TJ,Magnifouet Nana H,Ebelle Etame RM,Biyiti L,Ngono Ngane RA

    更新日期:2015-03-07 00:00:00

  • DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4.

    abstract:BACKGROUND:Chinese herbal formulae are composed of complex components and produce comprehensive pharmacological effects. Unlike chemical drugs that have only one clear single target, the components of Chinese herbal formulae have multiple channels and targets. How to discover the pharmacological targets of Chinese herb...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-67

    authors: Wang Y,Li C,Liu Z,Shi T,Wang Q,Li D,Wu Y,Han J,Guo S,Tang B,Wang W

    更新日期:2014-02-20 00:00:00

  • Effectiveness of acupuncture for breast cancer related lymphedema: protocol for a single-blind, sham-controlled, randomized, multicenter trial.

    abstract:BACKGROUND:Although various treatments for breast cancer related lymphedema exist, there is still a need for a more effective and convenient approach. Pilot studies and our clinical observations suggested that acupuncture may be a potential option. This study aims to verify the effectiveness of acupuncture on BCRL and ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-017-1980-0

    authors: Zhu H,Li J,Peng Z,Huang Y,Lv X,Song L,Zhou G,Lin S,Chen J,He B,Qin F,Liu X,Dai M,Zou Y,Dai S

    更新日期:2017-09-21 00:00:00

  • The anti-shigellosis activity of the methanol extract of Picralima nitida on Shigella dysenteriae type I induced diarrhoea in rats.

    abstract:BACKGROUND:Picralima nitida Stapf (Apocynaceae) is a medicinal plant used traditionally in Cameroon to cure various ailments such as gastrointestinal disorders and dysentery. This study reports the in vitro and in vivo anti-shigellosis activity of the methanol extract of this plant on rats. METHODS:The antimicrobial a...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-13-211

    authors: Kouitcheu LB,Tamesse JL,Kouam J

    更新日期:2013-08-17 00:00:00

  • Neuroprotective effects of Psoralea corylifolia Linn seed extracts on mitochondrial dysfunction induced by 3-nitropropionic acid.

    abstract:BACKGROUND:Mitochondrial dysfunction has been implicated in neuronal apoptosis associated with neurodegenerative diseases such as Huntington's disease (HD). Animals that are administered 3-nitropropionic acid (3-NP), a mitochondrial toxin that specifically inhibits complex II of the mitochondrial electron transport cha...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-370

    authors: Im AR,Chae SW,Zhang GJ,Lee MY

    更新日期:2014-10-03 00:00:00

  • Extracts of six Rubiaceae species combined with rifampicin have good in vitro synergistic antimycobacterial activity and good anti-inflammatory and antioxidant activities.

    abstract:BACKGROUND:The Rubiaceae family has played a significant role in drug discovery by providing molecules with potential use as templates for the development of therapeutic drugs. This study was designed to study the in vitro synergistic effect of six Rubiaceae species in combination with a known anti-TB drug. The antioxi...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-016-1355-y

    authors: Aro AO,Dzoyem JP,Eloff JN,McGaw LJ

    更新日期:2016-10-03 00:00:00

  • Complementary traditional Chinese medicine use in Children with cerebral palsy: a nationwide retrospective cohort study in Taiwan.

    abstract:BACKGROUND:Complementary traditional Chinese medicine (TCM) has been used to treat patients with cerebral palsy (CP). However, large-scale surveys examining its use in the treatment of CP and associated disorders are lacking. METHODS:We enrolled 11,218 patients ≤ 18 years of age with CP in the Taiwanese National Healt...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-017-1668-5

    authors: Liao HH,Yen HR,Muo CH,Lee YC,Wu MY,Chou LW,Sun MF,Chang TT

    更新日期:2017-03-14 00:00:00

  • In vitro determination of the anti-aging potential of four southern African medicinal plants.

    abstract:BACKGROUND:Aging is an inevitable process for all living organisms. During this process reactive oxygen species generation is increased which leads to the activation of hyaluronidase, collagenase and elastase, which can further contribute to skin aging. Four southern African medicinal plants; Clerodendrum glabrum, Scho...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-13-304

    authors: Ndlovu G,Fouche G,Tselanyane M,Cordier W,Steenkamp V

    更新日期:2013-11-05 00:00:00

  • Cytotoxicity effect of degraded and undegraded kappa and iota carrageenan in human intestine and liver cell lines.

    abstract:BACKGROUND:Carrageenan is a linear sulphated polysaccharide extracted from red seaweed of the Rhodophyceae family. It has broad spectrum of applications in biomedical and biopharmaceutical field. In this study, we determined the cytotoxicity of degraded and undegraded carrageenan in human intestine (Caco-2; cancer and ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-508

    authors: Ariffin SH,Yeen WW,Abidin IZ,Abdul Wahab RM,Ariffin ZZ,Senafi S

    更新日期:2014-12-17 00:00:00

  • The effects of Cordyceps sinensis phytoestrogen on estrogen deficiency-induced osteoporosis in ovariectomized rats.

    abstract:BACKGROUND:Isoflavones are naturally occurring plant chemicals belonging to the "phytoestrogen" class. The aim of the present study was to examine the effects of isoflavones obtained from Cordyceps sinensis (CSIF) on development of estrogen deficiency-induced osteoporosis in ovariectomized rats. METHODS:After the rats...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-484

    authors: Zhang DW,Wang ZL,Qi W,Zhao GY

    更新日期:2014-12-13 00:00:00

  • Optimization of extraction parameters of PTP1β (protein tyrosine phosphatase 1β), inhibitory polyphenols, and anthocyanins from Zea mays L. using response surface methodology (RSM).

    abstract:BACKGROUND:Protein tyrosine phosphatase expressed in insulin-sensitive tissues (such as liver, muscle, and adipose tissue) has a key role in the regulation of insulin signaling and pathway activation, making protein tyrosine phosphatase a promising target for the treatment of type 2 diabetes mellitus and obesity and re...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-016-1296-5

    authors: Hwang SH,Kwon SH,Wang Z,Kim TH,Kang YH,Lee JY,Lim SS

    更新日期:2016-08-26 00:00:00

  • Placebo by proxy expectations toward acupuncture change over time: a survey comparing parental expectations to acupuncture pre- and postoperatively.

    abstract:BACKGROUND:Patients entering a treatment have expectancy to outcome based on their previous experience, the information received, and the credibility of the treatment. Once the treatment has started, patients may detect and interpret contextual cues and somatic state. Influenced and conditioned by positive or negative ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12906-018-2248-z

    authors: Liodden I,Pripp AH,Norheim AJ

    更新日期:2018-06-14 00:00:00

  • Molecular insights into the anti-cancer properties of traditional Tibetan medicine Yukyung Karne.

    abstract:BACKGROUND:Yukyung karne (YK) is a traditional Tibetan formulation used for many centuries for the treatment of ovarian cancer. However, the pharmacological basis of its anticancer property is not well understood. In the present study, the anticancer property of YK was investigated in cell culture. METHODS:The growth ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-380

    authors: Choedon T,Dolma D,Mathan G,Kumar V

    更新日期:2014-10-07 00:00:00

  • Saikosaponin-d increases the radiosensitivity of smmc-7721 hepatocellular carcinoma cells by adjusting the g0/g1 and g2/m checkpoints of the cell cycle.

    abstract:BACKGROUND:Saikosaponin-d (SSd), a monomer terpenoid purified from the Chinese herbal drug Radix bupleuri, has multiple effects, including anticancer properties. However, the effect of SSd on tumors exposed to radiation is largely unknown. To investigate the radiosensitizing effect of SSd and its possible mechanism, we...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-13-263

    authors: Wang BF,Dai ZJ,Wang XJ,Bai MH,Lin S,Ma HB,Wang YL,Song LQ,Ma XL,Zan Y,Min WL,Cheng YA

    更新日期:2013-10-12 00:00:00

  • Perceptions, use and attitudes of pharmacy customers on complementary medicines and pharmacy practice.

    abstract:BACKGROUND:Complementary medicines (CMs) are popular amongst Australians and community pharmacy is a major supplier of these products. This study explores pharmacy customer use, attitudes and perceptions of complementary medicines, and their expectations of pharmacists as they relate to these products. METHODS:Pharmac...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-10-38

    authors: Braun LA,Tiralongo E,Wilkinson JM,Spitzer O,Bailey M,Poole S,Dooley M

    更新日期:2010-07-20 00:00:00

  • Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells.

    abstract:BACKGROUND:Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital objective for therapeutic intercession. This study investigated the neuro-protective effects of the demethoxycurcumin (DMC), a derivative of curc...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-017-1720-5

    authors: Ramkumar M,Rajasankar S,Gobi VV,Dhanalakshmi C,Manivasagam T,Justin Thenmozhi A,Essa MM,Kalandar A,Chidambaram R

    更新日期:2017-04-18 00:00:00

  • The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-κB pathway.

    abstract:BACKGROUND:Andrographis paniculata (Burm. f.) Nees (APN), a principal constituent of a famous traditional Chinese medicine Fukeqianjin tablet which is used for the treatment of pelvic inflammatory disease (PID), has been reported to have anti-inflammatory effect in vitro. However, whether it has pharmacological effect ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-016-1466-5

    authors: Zou W,Xiao Z,Wen X,Luo J,Chen S,Cheng Z,Xiang D,Hu J,He J

    更新日期:2016-11-25 00:00:00

  • Factors associated with herbal use among urban multiethnic primary care patients: a cross-sectional survey.

    abstract:BACKGROUND:The use of herbal supplements in the United States has become increasingly popular. The prevalence of herbal use among primary care patients varies in previous studies; the pattern of herbal use among urban racially/ethnically diverse primary care patients has not been widely studied. The primary objectives ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-4-18

    authors: Kuo GM,Hawley ST,Weiss LT,Balkrishnan R,Volk RJ

    更新日期:2004-12-02 00:00:00

  • Correction to: Acacia hydaspica R. Parker ameliorates cisplatin induced oxidative stress, DNA damage and morphological alterations in rat pulmonary tissue.

    abstract::Following publication of the original article [1], the author reported that Tables 3 and 4 were incorrect due to a production error. ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12906-019-2658-6

    authors: Afsar T,Razak S,Almajwal A,Khan MR

    更新日期:2019-11-07 00:00:00

  • In vitro antioxidant and anticancer effects of solvent fractions from Prunella vulgaris var. lilacina.

    abstract:BACKGROUND:Recently, considerable attention has been focused on exploring the potential antioxidant properties of plant extracts or isolated products of plant origin. Prunella vulgaris var. lilacina is widely distributed in Korea, Japan, China, and Europe, and it continues to be used to treat inflammation, eye pain, he...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-13-310

    authors: Hwang YJ,Lee EJ,Kim HR,Hwang KA

    更新日期:2013-11-09 00:00:00

  • Building resilience: a preliminary exploration of women's perceptions of the use of acupuncture as an adjunct to In Vitro Fertilisation.

    abstract:BACKGROUND:In Vitro Fertilisation (IVF) is now an accepted and effective treatment for infertility, however IVF is acknowledged as contributing to, rather than lessening, the overall psychosocial effects of infertility. Psychological and counselling interventions have previously been widely recommended in parallel with...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-9-50

    authors: de Lacey S,Smith CA,Paterson C

    更新日期:2009-12-12 00:00:00

  • Identification of nuclear factor-κB inhibitors in the folk herb Rhizoma Menispermi via bioactivity-based ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry analysis.

    abstract:BACKGROUND:Rhizoma Menispermi (RM) is the dried root of Menispermum dauricum DC, which is traditionally used to treat swelling and pain for sore throat, enteritis and rheumatic arthralgia in the clinic, but its bioactive compounds remain unclear. METHODS:In this study, RM extract was administered orally to ICR mice fo...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-14-356

    authors: Sun D,Zhou M,Ying X,Cheng B,Han Y,Nie Y,Hou Y,Bai G

    更新日期:2014-09-25 00:00:00

  • Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract.

    abstract:BACKGROUND:Green tea has polyphenols like flavonoids and catechins; mainly epigallocatechin-3-gallate (EGCG), epicatechin gallate (ECG), epigallocatechin (EGC) and epicatechin (EC), out of which EGCG is of higher abundance. EGCG has shown preventive role in hypercholesterolemia. However, due to low oral bioavailability...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-019-2545-1

    authors: Pandit AP,Joshi SR,Dalal PS,Patole VC

    更新日期:2019-06-13 00:00:00

  • Urox containing concentrated extracts of Crataeva nurvala stem bark, Equisetum arvense stem and Lindera aggregata root, in the treatment of symptoms of overactive bladder and urinary incontinence: a phase 2, randomised, double-blind placebo controlled tri

    abstract:BACKGROUND:Storage lower urinary tract symptoms (LUTS) including overactive bladder (OAB) and urinary incontinence (UI) affect millions of people worldwide, significantly impacting quality of life. Plant based medicines have been documented both empirically and in emerging scientific research to have varying benefits i...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12906-018-2101-4

    authors: Schoendorfer N,Sharp N,Seipel T,Schauss AG,Ahuja KDK

    更新日期:2018-01-31 00:00:00

  • Cytotoxicity of Brazilian plant extracts against oral microorganisms of interest to dentistry.

    abstract:BACKGROUND:With the emergence of strains resistant to conventional antibiotics, it is important to carry studies using alternative methods to control these microorganisms causing important infections, such as the use of products of plant origin that has demonstrated effective antimicrobial activity besides biocompatibi...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/1472-6882-13-208

    authors: de Oliveira JR,de Castro VC,das Graças Figueiredo Vilela P,Camargo SE,Carvalho CA,Jorge AO,de Oliveira LD

    更新日期:2013-08-15 00:00:00

  • Mining the deep Red-Sea brine pool microbial community for anticancer therapeutics.

    abstract:BACKGROUND:Microbial species in the brine pools of the Red Sea and the brine pool-seawater interfaces are exposed to high temperature, high salinity, low oxygen levels and high concentrations of heavy metals. As adaptations to these harsh conditions require a large suite of secondary metabolites, these microbes have a ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-019-2554-0

    authors: Esau L,Zhang G,Sagar S,Stingl U,Bajic VB,Kaur M

    更新日期:2019-06-20 00:00:00

  • Sheng-ji Hua-yu formula promotes diabetic wound healing of re-epithelization via Activin/Follistatin regulation.

    abstract:BACKGROUND:Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound. However, elucidating the related molecular biological mechanism of how the SJHY Formula affects excessive inflammation in the process of re-epithelialization of diabetic ...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-017-2074-8

    authors: Kuai L,Zhang JT,Deng Y,Xu S,Xu XZ,Wu MF,Guo DJ,Chen Y,Wu RJ,Zhao XQ,Nian H,Li B,Li FL

    更新日期:2018-01-29 00:00:00

  • Rhein exhibits antioxidative effects similar to Rhubarb in a rat model of traumatic brain injury.

    abstract:BACKGROUND:The brain is secondarily harmed by pathological, physiological, and biological reactions that are caused by traumatic brain injury (TBI). Rhein, a significant composition of Rhubarb, is a well-known traditional Chinese treatment method and has a strong oxidation-resisting characteristic, but Rhein's mechanis...

    journal_title:BMC complementary and alternative medicine

    pub_type: 杂志文章

    doi:10.1186/s12906-017-1655-x

    authors: Xu X,Lv H,Xia Z,Fan R,Zhang C,Wang Y,Wang D

    更新日期:2017-03-07 00:00:00