Mental imagery-induced attention modulates pain perception and cortical excitability.

Abstract:

BACKGROUND:Mental imagery is a powerful method of altering brain activity and behavioral outcomes, such as performance of cognition and motor skills. Further, attention and distraction can modulate pain-related neuronal networks and the perception of pain. This exploratory study examined the effects of mental imagery-induced attention on pressure pain threshold and cortical plasticity using transcranial magnetic stimulation (TMS). This blinded, randomized, and parallel-design trial comprised 30 healthy right-handed male subjects. Exploratory statistical analyses were performed using ANOVA and t-tests for pain and TMS assessments. Pearson's correlation was used to analyze the association between changes in pain threshold and cortical excitability. RESULTS:In the analysis of pain outcomes, there was no significant interaction effect on pain between group versus time. In an exploratory analysis, we only observed a significant effect of group for the targeted left hand (ANOVA with pain threshold as the dependent variable and time and group as independent variables). Although there was only a within-group effect of mental imagery on pain, further analyses showed a significant positive correlation of changes in pain threshold and cortical excitability (motor-evoked potentials via TMS). CONCLUSIONS:Mental imagery has a minor effect on pain modulation in healthy subjects. Its effects appear to differ compared with chronic pain, leading to a small decrease in pain threshold. Assessments of cortical excitability confirmed that these effects are related to the modulation of pain-related cortical circuits. These exploratory findings suggest that neuronal plasticity is influenced by pain and that the mental imagery effects on pain depend on the state of central sensitization.

journal_name

BMC Neurosci

journal_title

BMC neuroscience

authors

Volz MS,Suarez-Contreras V,Portilla AL,Fregni F

doi

10.1186/s12868-015-0146-6

subject

Has Abstract

pub_date

2015-03-15 00:00:00

pages

15

issn

1471-2202

pii

10.1186/s12868-015-0146-6

journal_volume

16

pub_type

杂志文章,随机对照试验
  • Plasticity in neuromagnetic cortical responses suggests enhanced auditory object representation.

    abstract:BACKGROUND:Auditory perceptual learning persistently modifies neural networks in the central nervous system. Central auditory processing comprises a hierarchy of sound analysis and integration, which transforms an acoustical signal into a meaningful object for perception. Based on latencies and source locations of audi...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-14-151

    authors: Ross B,Jamali S,Tremblay KL

    更新日期:2013-12-05 00:00:00

  • Efficacy of antidotes (midazolam, atropine and HI-6) on nerve agent induced molecular and neuropathological changes.

    abstract:BACKGROUND:Recent alleged attacks with nerve agent sarin on civilians in Syria indicate their potential threat to both civilian and military population. Acute nerve agent exposure can cause rapid death or leads to multiple and long term neurological effects. The biochemical changes that occur following nerve agent expo...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-15-47

    authors: RamaRao G,Afley P,Acharya J,Bhattacharya BK

    更新日期:2014-04-04 00:00:00

  • Tricyclic pyrone compounds prevent aggregation and reverse cellular phenotypes caused by expression of mutant huntingtin protein in striatal neurons.

    abstract:BACKGROUND:Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a CAG repeat expansion mutation in the coding region of a novel gene. The mechanism of HD is unknown. Most data suggest that polyglutamine-mediated aggregation associated with expression of mutant huntingtin protein (mhtt) contri...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-10-73

    authors: Trushina E,Rana S,McMurray CT,Hua DH

    更新日期:2009-07-08 00:00:00

  • Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain.

    abstract:BACKGROUND:Neurogenesis continues to occur throughout life but dramatically decreases with increasing age. This decrease is mostly related to a decline in proliferative activity as a result of an impoverishment of the microenvironment of the aged brain, including a reduction in trophic factors and increased inflammatio...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-9-22

    authors: Bachstetter AD,Pabon MM,Cole MJ,Hudson CE,Sanberg PR,Willing AE,Bickford PC,Gemma C

    更新日期:2008-02-14 00:00:00

  • Genomic responses in rat cerebral cortex after traumatic brain injury.

    abstract:BACKGROUND:Traumatic brain injury (TBI) initiates a complex sequence of destructive and neuroprotective cellular responses. The initial mechanical injury is followed by an extended time period of secondary brain damage. Due to the complicated pathological picture a better understanding of the molecular events occurring...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-6-69

    authors: von Gertten C,Flores Morales A,Holmin S,Mathiesen T,Nordqvist AC

    更新日期:2005-11-30 00:00:00

  • NKCC1 downregulation induces hyperpolarizing shift of GABA responsiveness at near term fetal stages in rat cultured dorsal root ganglion neurons.

    abstract:BACKGROUND:GABAA receptor-mediated neurotransmission is greatly influenced by cation-chloride cotransporter activity during developmental stages. In embryonic neurons Na-K-2Cl (NKCC1) cotransporters mediate active chloride uptake, thus increasing the intracellular chloride concentration associated with GABA-induced dep...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/s12868-015-0180-4

    authors: Chabwine JN,Talavera K,Van Den Bosch L,Callewaert G

    更新日期:2015-07-14 00:00:00

  • Immunization with neural derived peptides plus scar removal induces a permissive microenvironment, and improves locomotor recovery after chronic spinal cord injury.

    abstract:BACKGROUND:Immunization with neural derived peptides (INDP) as well as scar removal-separately-have shown to induce morphological and functional improvement after spinal cord injury (SCI). In the present study, we compared the effect of INDP alone versus INDP with scar removal on motor recovery, regeneration-associated...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/s12868-016-0331-2

    authors: Rodríguez-Barrera R,Flores-Romero A,Fernández-Presas AM,García-Vences E,Silva-García R,Konigsberg M,Blancas-Espinoza L,Buzoianu-Anguiano V,Soria-Zavala K,Suárez-Meade P,Ibarra A

    更新日期:2017-01-05 00:00:00

  • VAMP-2, SNAP-25A/B and syntaxin-1 in glutamatergic and GABAergic synapses of the rat cerebellar cortex.

    abstract:BACKGROUND:The aim of this study was to assess the distribution of key SNARE proteins in glutamatergic and GABAergic synapses of the adult rat cerebellar cortex using light microscopy immunohistochemical techniques. Analysis was made of co-localizations of vGluT-1 and vGluT-2, vesicular transporters of glutamate and ma...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-12-118

    authors: Benagiano V,Lorusso L,Flace P,Girolamo F,Rizzi A,Bosco L,Cagiano R,Nico B,Ribatti D,Ambrosi G

    更新日期:2011-11-17 00:00:00

  • Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes.

    abstract:BACKGROUND:The properties of Ca2+ signaling mediated by purinergic receptors are intrinsically linked with functional activity of astrocytes. At present little is known concerning Ca2+-dependent purinergic responses in adult human astrocytes. This work has examined effects of purinergic stimulation to alter levels of i...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-15-18

    authors: Hashioka S,Wang YF,Little JP,Choi HB,Klegeris A,McGeer PL,McLarnon JG

    更新日期:2014-01-22 00:00:00

  • Astaxanthin alleviates cerebral edema by modulating NKCC1 and AQP4 expression after traumatic brain injury in mice.

    abstract:BACKGROUND:Astaxanthin is a carotenoid pigment that possesses potent antioxidative, anti-inflammatory, antitumor, and immunomodulatory activities. Previous studies have demonstrated that astaxanthin displays potential neuroprotective properties for the treatment of central nervous system diseases, such as ischemic brai...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/s12868-016-0295-2

    authors: Zhang M,Cui Z,Cui H,Cao Y,Zhong C,Wang Y

    更新日期:2016-08-31 00:00:00

  • Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity.

    abstract:BACKGROUND:Recent discoveries suggest that arealization of the mammalian cortical sheet develops in a manner consonant with principles established for embryonic patterning of the body. Signaling centers release morphogens that determine regional growth and tissue identity by regulating regional expression of transcript...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-6-18

    authors: Airey DC,Robbins AI,Enzinger KM,Wu F,Collins CE

    更新日期:2005-03-17 00:00:00

  • Ultrastructure of acetylcholine receptor aggregates parallels mechanisms of aggregation.

    abstract:BACKGROUND:Acetylcholine receptors become aggregated at the developing neuromuscular synapse shortly after contact by a motorneuron in one of the earliest manifestations of synaptic development. While a major physiological signal for receptor aggregation (agrin) is known, the mechanism(s) by which muscle cells respond ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-2-19

    authors: Kunkel DD,Lee LK,Stollberg J

    更新日期:2001-01-01 00:00:00

  • Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model.

    abstract:BACKGROUND:Overexpression and abnormal accumulation of aggregated alpha-synuclein (alphaS) have been linked to Parkinson's disease (PD) and other synucleinopathies. alphaS can misfold and adopt a variety of morphologies but recent studies implicate oligomeric forms as the most cytotoxic species. Both genetic mutations ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-11-57

    authors: Wang MS,Boddapati S,Emadi S,Sierks MR

    更新日期:2010-04-30 00:00:00

  • Callosal connections of dorsal versus ventral premotor areas in the macaque monkey: a multiple retrograde tracing study.

    abstract:BACKGROUND:The lateral premotor cortex plays a crucial role in visually guided limb movements. It is divided into two main regions, the dorsal (PMd) and ventral (PMv) areas, which are in turn subdivided into functionally and anatomically distinct rostral (PMd-r and PMv-r) and caudal (PMd-c and PMv-c) sub-regions. We an...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-6-67

    authors: Boussaoud D,Tanné-Gariépy J,Wannier T,Rouiller EM

    更新日期:2005-11-25 00:00:00

  • Expression of ATF3 and axonal outgrowth are impaired after delayed nerve repair.

    abstract:BACKGROUND:A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-9-88

    authors: Saito H,Dahlin LB

    更新日期:2008-09-18 00:00:00

  • Anticipating the course of an action: evidence from corticospinal excitability.

    abstract:BACKGROUND:Anticipatory planning, the ability to anticipate future perceptual-motor demands of a goal-oriented action sequence, is essential for flexible, purposeful behavior. Once an action goal has been defined, movement details necessary to achieve that goal can be selected. Here, we investigate if anticipatory plan...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-14-91

    authors: Marangon M,Bucchioni G,Massacesi S,Castiello U

    更新日期:2013-08-28 00:00:00

  • The relationship between magnetic and electrophysiological responses to complex tactile stimuli.

    abstract:BACKGROUND:Magnetoencephalography (MEG) has become an increasingly popular technique for non-invasively characterizing neuromagnetic field changes in the brain at a high temporal resolution. To examine the reliability of the MEG signal, we compared magnetic and electrophysiological responses to complex natural stimuli ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-10-4

    authors: Zhu Z,Zumer JM,Lowenthal ME,Padberg J,Recanzone GH,Krubitzer LA,Nagarajan SS,Disbrow EA

    更新日期:2009-01-15 00:00:00

  • The BOLD response and the gamma oscillations respond differently than evoked potentials: an interleaved EEG-fMRI study.

    abstract:BACKGROUND:The integration of EEG and fMRI is attractive because of their complementary precision regarding time and space. But the relationship between the indirect hemodynamic fMRI signal and the more direct EEG signal is uncertain. Event-related EEG responses can be analyzed in two different ways, reflecting two dif...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-4-22

    authors: Foucher JR,Otzenberger H,Gounot D

    更新日期:2003-09-19 00:00:00

  • Sensitivity of the human auditory cortex to acoustic degradation of speech and non-speech sounds.

    abstract:BACKGROUND:Recent studies have shown that the human right-hemispheric auditory cortex is particularly sensitive to reduction in sound quality, with an increase in distortion resulting in an amplification of the auditory N1m response measured in the magnetoencephalography (MEG). Here, we examined whether this sensitivit...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-11-24

    authors: Miettinen I,Tiitinen H,Alku P,May PJ

    更新日期:2010-02-22 00:00:00

  • Cholecystokinin receptor-1 mediates the inhibitory effects of exogenous cholecystokinin octapeptide on cellular morphine dependence.

    abstract:BACKGROUND:Cholecystokinin octapeptide (CCK-8), the most potent endogenous anti-opioid peptide, has been shown to regulate the processes of morphine dependence. In our previous study, we found that exogenous CCK-8 attenuated naloxone induced withdrawal symptoms. To investigate the precise effect of exogenous CCK-8 and ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-13-63

    authors: Wen D,Ma CL,Zhang YJ,Meng YX,Ni ZY,Li SJ,Cong B

    更新日期:2012-06-08 00:00:00

  • Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study.

    abstract:BACKGROUND:One of the most basic human traits is language. Linguistic ability, and disability, have been shown to have a strong genetic component in family and twin studies, but molecular genetic studies of language phenotypes are scarce, relative to studies of other cognitive traits and neurodevelopmental phenotypes. ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/s12868-020-00581-5

    authors: Nudel R,Christiani CAJ,Ohland J,Uddin MJ,Hemager N,Ellersgaard D,Spang KS,Burton BK,Greve AN,Gantriis DL,Bybjerg-Grauholm J,Jepsen JRM,Thorup AAE,Mors O,Werge T,Nordentoft M

    更新日期:2020-07-07 00:00:00

  • Occipital repetitive transcranial magnetic stimulation does not affect multifocal visual evoked potentials.

    abstract:BACKGROUND:To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make a valuable contribution as they are not associated with cancellation artifacts and include also the...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/s12868-020-00600-5

    authors: Kolbe R,Aytulun A,Müller AK,Ringelstein M,Aktas O,Schnitzler A,Hartung HP,Groiss SJ,Albrecht P

    更新日期:2020-11-23 00:00:00

  • Pure phase-locking of beta/gamma oscillation contributes to the N30 frontal component of somatosensory evoked potentials.

    abstract:BACKGROUND:Evoked potentials have been proposed to result from phase-locking of electroencephalographic (EEG) activities within specific frequency bands. However, the respective contribution of phasic activity and phase resetting of ongoing EEG oscillation remains largely debated. We here applied the EEGlab procedure i...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-8-75

    authors: Cheron G,Cebolla AM,De Saedeleer C,Bengoetxea A,Leurs F,Leroy A,Dan B

    更新日期:2007-09-18 00:00:00

  • Looking for a pattern: an MEG study on the abstract mismatch negativity in musicians and nonmusicians.

    abstract:BACKGROUND:The mismatch negativity (MMN) is an early component of event-related potentials/fields, which can be observed in response to violations of regularities in sound sequences. The MMN can be elicited by simple feature (e.g. pitch) deviations in standard oddball paradigms as well as by violations of more complex ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-10-42

    authors: Herholz SC,Lappe C,Pantev C

    更新日期:2009-04-30 00:00:00

  • Effects of brain polarization on reaction times and pinch force in chronic stroke.

    abstract:BACKGROUND:Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities of daily living (ADL). It is not known if relatively s...

    journal_title:BMC neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2202-7-73

    authors: Hummel FC,Voller B,Celnik P,Floel A,Giraux P,Gerloff C,Cohen LG

    更新日期:2006-11-03 00:00:00

  • A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction.

    abstract:BACKGROUND:The megencephaly mouse, mceph/mceph, is epileptic and displays a dramatically increased brain volume and neuronal count. The responsible mutation was recently revealed to be an eleven base pair deletion, leading to a frame shift, in the gene encoding the potassium channel Kv1.1. The predicted MCEPH protein i...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-6-65

    authors: Persson AS,Klement G,Almgren M,Sahlholm K,Nilsson J,Petersson S,Arhem P,Schalling M,Lavebratt C

    更新日期:2005-11-23 00:00:00

  • Recognition of face-name associations after errorless and errorful learning: an fMRI study.

    abstract:BACKGROUND:Errorless learning has advantages over errorful learning. The erroneous items produced during errorful learning compete with correct items at retrieval resulting in decreased memory performance. This interference is associated with an increased demand on executive monitoring processes. Event-related function...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-14-30

    authors: Hammer A,Tempelmann C,Münte TF

    更新日期:2013-03-13 00:00:00

  • The influence of language deprivation in early childhood on L2 processing: An ERP comparison of deaf native signers and deaf signers with a delayed language acquisition.

    abstract:BACKGROUND:To examine which language function depends on early experience, the present study compared deaf native signers, deaf non-native signers and hearing German native speakers while processing German sentences. The participants watched simple written sentences while event-related potentials (ERPs) were recorded. ...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-13-44

    authors: Skotara N,Salden U,Kügow M,Hänel-Faulhaber B,Röder B

    更新日期:2012-05-03 00:00:00

  • Geometric morphometrics defines shape differences in the cortical area map of C57BL/6J and DBA/2J inbred mice.

    abstract:BACKGROUND:We previously described planar areal differences in adult mouse visual, somatosensory, and neocortex that collectively discriminated C57BL/6J and DBA/2J inbred strain identity. Here we use a novel application of established methods of two-dimensional geometric morphometrics to examine shape differences in th...

    journal_title:BMC neuroscience

    pub_type: 杂志文章

    doi:10.1186/1471-2202-7-63

    authors: Airey DC,Wu F,Guan M,Collins CE

    更新日期:2006-09-15 00:00:00

  • Functional connectivity profile of the human inferior frontal junction: involvement in a cognitive control network.

    abstract:BACKGROUND:The human inferior frontal junction area (IFJ) is critically involved in three main component processes of cognitive control (working memory, task switching and inhibitory control). As it overlaps with several areas in established anatomical labeling schemes, it is considered to be underreported as a functio...

    journal_title:BMC neuroscience

    pub_type: 杂志文章,meta分析

    doi:10.1186/1471-2202-13-119

    authors: Sundermann B,Pfleiderer B

    更新日期:2012-10-03 00:00:00