Reference ranges for an automated chemiluminescent assay for serum insulin-like growth factor I (IGF-I) in a large population of healthy adults from Buenos Aires.

abstract：BACKGROUND:Leptin and ghrelin appear to play a role in weight regain after a successful weight loss. The pre-treatment plasma levels of leptin/ghrelin ratio (L/G) could have power to predict this clinically relevant issue in the obesity treatment. OBJECTIVE:To evaluate the ability of the L/G as a non-invasive tool for...

journal_title：Journal of endocrinological investigation

authors： Crujeiras AB,Díaz-Lagares A,Abete I,Goyenechea E,Amil M,Martínez JA,Casanueva FF

更新日期：2014-02-01 00:00:00

abstract：:1-123 metaiodobenzylguanidine (1-123 MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. In this rare case report, we describe a definite adrenocortical adenoma that demonstrated false-positive uptake at I-123 MIBG scintigraphy and a remarkable ac...

journal_title：Journal of endocrinological investigation

authors： Letizia C,De Toma G,Massa R,Corsi A,Caliumi C,Subioli S,D'Erasmo E

更新日期：1998-12-01 00:00:00

abstract：:The aim of acromegaly treatment is to control the disease by suppressing GH hyperactivity and reducing the size or impeding the growth of the pituitary GH secreting mass. Over recent years, many studies have emphasized the role of SS analogs in the treatment of acromegaly. In fact, SS analogs have been demonstrated to...

journal_title：Journal of endocrinological investigation

authors： Gola M,Bonadonna S,Mazziotti G,Amato G,Giustina A

更新日期：2006-01-01 00:00:00

abstract：:It has been reported that adult obese subjects present a reduced growth hormone secretion. As no data are available in the pubertal period, which is characterized in lean subjects by an increased spontaneous growth hormone secretion, the growth hormone circadian concentration was studied in a group of 18 obese male su...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Del Monte P,Fortini P,Resentini M,Morabito F,Giordano G

更新日期：1988-07-01 00:00:00

abstract：:Eleven patients with Paget's disease of bone, treated intermittently for 2-4 years with porcine calcitonin (pCT) and clinically resistant to pCT [no modifications of serum alkaline phosphatase (ALP) and urinary hydroxyproline ( uHOP ) during pCT administration] were treated with 0.5-0.25 mg/day of human calcitonin (hC...

journal_title：Journal of endocrinological investigation

authors： Lo Cascio V,Adami S,Galvanini G,Lazzaretto R,Ferrari M,Tartarotti D,Scuro LA

更新日期：1984-04-01 00:00:00

abstract：PURPOSE:PATRO adults is an ongoing, multicenter, observational, post-marketing surveillance study aimed at investigating the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the recombinant human growth hormone (rhGH) Omnitrope® during routine clinical practice. This report describes data f...

journal_title：Journal of endocrinological investigation

authors： Arosio M,Arnaldi G,Gasco V,Giavoli C,Puxeddu E,Vettor R,Ambrosio MR,Gallinari P,Zouater H,Fedeli P,Ferone D

更新日期：2021-02-01 00:00:00

abstract：:In 1992 a significant relationship between bone turnover and the vitamin D receptor (VDR) genotype was reported in Australian subjects of UK-Irish decent. Since then, several groups have investigated the relationship between VDR and other bone-related genotypes, bone mass and bone turnover in several populations. Howe...

journal_title：Journal of endocrinological investigation

authors： Sheehan D,Bennett T,Cashman KD

更新日期：2001-04-01 00:00:00

abstract：:Adrenal origin and ACTH-dependent secretion of endogenous digitalis-like factor(s) (EDLF) was investigated. Twelve normal weight normotensive subjects (normal group) and 10 patients with Addison's disease (Addison group) were subjected to prolonged ACTH stimulation with 1 mg tetracosactin-depot im. Blood sampling was ...

journal_title：Journal of endocrinological investigation

authors： Sophocleous A,Elmatzoglou I,Souvatzoglou A

更新日期：2003-07-01 00:00:00

abstract：:The TSH responses to the catecholamine depleting agent monoiodotyrosine (1 g po) and the dopamine receptor blocking drug metoclopramide (10 mg po) have been compared in euthyroid and hypothyroid subjects. Both drugs lead to a prompt and significant rise in TSH levels (peak values at 60-75 min) which is very much great...

journal_title：Journal of endocrinological investigation

authors： Scanlon MF,Rodriguez-Arnao MD,Pourmand M,Shale DJ,Weightman DR,Lewis M,Hall R

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:In vitro data have shown conflicting results in terms of the effect of leptin on granulosa cells steroidogenesis. AIM:The aim of the present study was to investigate the effect of low and high doses of leptin on basal and FSH-induced steroids secretion by human luteinized granulosa cells in culture. MATERI...

journal_title：Journal of endocrinological investigation

authors： Karamouti M,Kollia P,Kallitsaris A,Vamvakopoulos N,Kollios G,Messinis IE

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To report the long-term effectiveness and safety of the recombinant human growth hormone Omnitrope®, a somatropin biosimilar to Genotropin®, in Italian patients with growth hormone deficiency (GHD) enrolled in the PATRO Adults study. METHODS:The PATRO Adults study is an ongoing observational, longitudinal, non...

journal_title：Journal of endocrinological investigation

authors： Ferone D,Profka E,Gasco V,Ambrosio MR,Colao A,Di Somma C,Puxeddu E,Arnaldi G,Pagano C,Zecchi E,Pietropoli A,Beck-Peccoz P

更新日期：2017-06-01 00:00:00

abstract：:Over the past years, the use of genetically encoded Ca(2+) indicators (GECIs), derived from aequorin and green fluorescent protein, has profoundly transformed the study of Ca(2+) homeostasis in living cells leading to novel insights into functional aspects of Ca(2+) signalling. Particularly relevant for a deeper under...

journal_title：Journal of endocrinological investigation

authors： Pendin D,Greotti E,Filadi R,Pozzan T

更新日期：2015-01-01 00:00:00

abstract：:In mature female rats the administration of testosterone led to a striking reduction of hepatic alcohol dehydrogenase activity, whereas the hepatic microsomal ethanol oxidizing system as well as catalase were both increased in activity under these experimental conditions. Conversely, estradiol left the activities of a...

journal_title：Journal of endocrinological investigation

authors： Teschke R,Wiese B

更新日期：1982-07-01 00:00:00

abstract：OBJECTIVE:Increased inhibin A serum and plasma levels in the second trimester are significantly associated with the development of preeclampsia. The measurement of inhibin A during early pregnancies may be helpful to predict those at risk of this disorder. The purpose of this study was to determine whether the 769G>A v...

journal_title：Journal of endocrinological investigation

authors： Kim SY,Lim JH,Yang JH,Kim MY,Kim MH,Park SY,Ryu HM

更新日期：2008-08-01 00:00:00

abstract：INTRODUCTION:Interleukins and cytokines play an important role in the pathogenesis of many cancers.We aimed to evaluate the interleukin (IL)-6 gene polymorphisms in patients with papillary thyroid carcinoma (PTC) and control subjects. MATERIAL AND METHODS:In this study, 42 patients with PTC and 340 healthy controls we...

journal_title：Journal of endocrinological investigation

authors： Ozgen AG,Karadeniz M,Erdogan M,Berdeli A,Saygili F,Yilmaz C

更新日期：2009-06-01 00:00:00

abstract：:The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate...

journal_title：Journal of endocrinological investigation

authors： Basaria S,McCarthy EF,Belzberg AJ,Ball DW

更新日期：2000-09-01 00:00:00

abstract：:Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...

journal_title：Journal of endocrinological investigation

authors： Giusti M,Guido R,Valenti S,Giordano G

更新日期：1999-01-01 00:00:00

abstract：:Thyrocytes from normal and goitrous portions of the thyroid gland from a patient with an enormous (635 gm) goiter were cultured in media, and their relative abilities to uptake thymidine, synthesize DNA, and secrete Tg and T4 were assessed. Tg, T4 and the ratio Tg/T4 in media at 72 h were 120 micrograms/dl, 1.6 microg...

journal_title：Journal of endocrinological investigation

authors： Tseng YC,Burman KD,Baker JR Jr,D'Avis J,Wartofsky L

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:Thyroid hormone resistance (RTH β) is a rare genetic disorder characterized by an altered response of target tissue to the action of thyroid hormone. Few studies on RTH β have been carried out in southern European populations. We aimed to describe the clinical and genetic characteristics at the time of diagno...

journal_title：Journal of endocrinological investigation

authors： Vela A,Pérez-Nanclares G,Ríos I,Rica I,Portillo N,Castaño L,Spanish Group for the Study of RTH.

更新日期：2019-08-01 00:00:00

abstract：:The diagnosis of growth hormone (GH) deficiency (GHD) is currently based on failure to increase plasma GH levels to an arbitrary cutoff point of 7 or 10 micrograms/l in response to two provocative stimuli. False negative responses to these tests, however, frequently occur thus reducing their diagnostic reliability. Th...

journal_title：Journal of endocrinological investigation

authors： Ghigo E,Imperiale E,Boffano GM,Mazza E,Bellone J,Arvat E,Procopio M,Goffi S,Barreca A,Chiabotto P

更新日期：1990-04-01 00:00:00

abstract：:Multiple pituitary hormone hypersecretions have already been described, but the co-occurrence of PRL and ACTH excess is very rare. To our knowledge, medical treatment with cabergoline only, avoiding pituitary surgery and radiotherapy in this type of tumor has never been reported before. This case report deals with a 3...

journal_title：Journal of endocrinological investigation

authors： T'Sjoen G,Defeyter I,Van De Saffele J,Rubens R,Vandeweghe M

更新日期：2002-02-01 00:00:00

abstract：:A 39-year-old Danish woman was treated with an oral dose of 400 MBq 131I for a non-toxic goiter with compression symptoms. Serum anti-TPO and TSH receptor antibodies were negative before radioiodine therapy. The patient developed hyperthyroidism four months after treatment and ophthalmopathy after another three months...

journal_title：Journal of endocrinological investigation

authors： Nygaard B,Metcalfe RA,Phipps J,Weetman AP,Hegedüs L

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:The Merseburg triad (hyperthyroidism, goiter, and orbitopathy) characterizes classical description of Graves' disease (GD). Aim of this observational, longitudinal study was to evaluate the current clinical features of newly diagnosed GD in Italy. MATERIALS AND METHODS:In two Northern Italy centers (Varese a...

journal_title：Journal of endocrinological investigation

authors： Bartalena L,Masiello E,Magri F,Veronesi G,Bianconi E,Zerbini F,Gaiti M,Spreafico E,Gallo D,Premoli P,Piantanida E,Tanda ML,Ferrario M,Vitti P,Chiovato L

更新日期：2016-12-01 00:00:00

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is characterized by parathyroid, enteropancreatic endocrine and pituitary adenomas as well as germline mutation of the MEN1 gene. We describe 2 families with MEN1 with novel mutations in the MEN1 gene. One family was of Turkish origin, and the index patient had primary hyperp...

journal_title：Journal of endocrinological investigation

authors： Ozturk M,Chiu CY,Akdeniz N,Jenq SF,Chang SC,Hsa CY,Jap TS

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Visfatin [pre-B cell colony- enhancing factor (PBEF)] is a cytokine highly expressed in visceral fat that exhibits insulin-mimetic properties. However, its role in insulin-resistant states, such as in metabolic syndrome (MetS), remains largely unknown. OBJECTIVE:To investigate the possible differences of pl...

journal_title：Journal of endocrinological investigation

authors： Filippatos TD,Derdemezis CS,Kiortsis DN,Tselepis AD,Elisaf MS

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Due to the lack of specific pediatric studies, no data are available about natural history of endogenous subclinical hyperthyroidism (SH) in childhood. AIMS:(a) To investigate for the first time the natural history of SH [suppressed thyrotropin (TSH) and normal free thyroxine free thyroxine (FT4) levels] wh...

journal_title：Journal of endocrinological investigation

authors： Aversa T,Valenzise M,Corrias A,Salerno M,Mussa A,Capalbo D,Salzano G,De Luca F,Wasniewska M

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:In our previous study, we introduced a rat model of polycystic ovary syndrome (PCOS) induced by prenatal exposure to a single dose of testosterone on embryonic day 20. In the current study, we aimed to investigate whether prenatal exposure to a single dose of testosterone could also induce metabolic disturbance...

journal_title：Journal of endocrinological investigation

authors： Noroozzadeh M,Ramezani Tehrani F,Sedaghat K,Godini A,Azizi F

更新日期：2015-05-01 00:00:00

abstract：:Resistance to thyroid hormone (RTH) is a rare disease characterized by non-suppressed TSH in spite of high free thyroid hormone levels. Up to date, in the literature, there are more than 600 RTH cases, but co-incidental hypophyseal adenoma was reported in only 1 case. In the literature, despite reported cases with thy...

journal_title：Journal of endocrinological investigation

authors： Berker D,Aydin Y,Tutuncu YA,Isik S,Delibasi T,Berker M,Guler S,Kamel N

更新日期：2009-03-01 00:00:00

abstract：:Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...

journal_title：Journal of endocrinological investigation

authors： Park S,Hwang I,Shong M,Kwon OY

更新日期：2003-02-01 00:00:00