Oligometastases in prostate cancer: restaging stage IV cancers and new radiotherapy options.

abstract：PURPOSE:To assess whether an expanded (five level) risk stratification system can be used to identify the sub-group of intermediate risk patients with prostate cancer who benefit from combining androgen deprivation therapy (ADT) with external beam radiotherapy (EBRT). MATERIALS AND METHODS:Using a previously validated...

journal_title：Radiation oncology (London, England)

authors： Beasley M,Williams SG,Pickles T,BCCA Prostate Outcomes Unit.

更新日期：2008-04-18 00:00:00

abstract：BACKGROUND:The effects of spinal implants on dose distribution have been studied for conformal treatment plans. However, the dosimetric impact of spinal implants in stereotactic body radiotherapy (SBRT) treatments has not been studied in spatial orientation. In this study we evaluated the effect of spinal implants plac...

journal_title：Radiation oncology (London, England)

authors： Yazici G,Sari SY,Yedekci FY,Yucekul A,Birgi SD,Demirkiran G,Gultekin M,Hurmuz P,Yazici M,Ozyigit G,Cengiz M

更新日期：2016-05-25 00:00:00

abstract：BACKGROUND:Neoadjuvant external-beam radiotherapy (EBRT) with concomitant chemotherapy is the current standard-of-care for locally-advanced rectal cancer. Intraoperative radiotherapy (IORT) is to date only recommended for pelvic recurrences or incompletely resectable tumors. We here report on patients with stage II/III...

journal_title：Radiation oncology (London, England)

authors： Potemin S,Kübler J,Uvarov I,Wenz F,Giordano F

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:We investigated patterns of failure in patients with locally advanced rectal cancer (LARC) according to chemoradiotherapy (CRT) timing: pre-operative versus post-operative. Also, patterns of failure, particularly distant metastasis (DM), were analyzed according to tumor location within the rectum. METHODS:I...

journal_title：Radiation oncology (London, England)

authors： Yeo SG,Kim MJ,Kim DY,Chang HJ,Kim MJ,Baek JY,Kim SY,Kim TH,Park JW,Oh JH

更新日期：2013-05-06 00:00:00

abstract：PURPOSE:This study examined the population-based use and outcomes of brain radiotherapy (BRT) for brain metastases (BM) from breast cancer with a focus on repeat BRT in the trastuzumab era. METHODS AND MATERIALS:All women with breast cancer diagnosed from 2000-2007 and treated with BRT were retrospectively identified ...

journal_title：Radiation oncology (London, England)

authors： Karam I,Nichol A,Woods R,Tyldesley S

更新日期：2011-12-28 00:00:00

abstract：BACKGROUND:To compare the accuracy of different imaging modalities, alone and in combination in predicting findings at surgery after preoperative chemoradiation for locally advanced rectal cancer. METHODS:Following chemoradiation, tumors were reclassified on the basis of findings on pelvic computed tomography (CT) (94...

journal_title：Radiation oncology (London, England)

authors： Dickman R,Kundel Y,Levy-Drummer R,Purim O,Wasserberg N,Fenig E,Sulkes A,Brenner B

更新日期：2013-11-29 00:00:00

abstract：:In cells exposed to low linear energy transfer (LET) ionizing-radiation (IR), double-strand-breaks (DSBs) form within clustered-damage-sites (CDSs) from lesions disrupting the DNA sugar-phosphate backbone. It is commonly assumed that all DSBs form promptly and are immediately detected by the cellular DNA-damage-respon...

journal_title：Radiation oncology (London, England)

authors： Singh SK,Bencsik-Theilen A,Mladenov E,Jakob B,Taucher-Scholz G,Iliakis G

更新日期：2013-04-02 00:00:00

abstract：PURPOSE:To evaluate the efficacy of proton beam therapy (PBT) for pediatric patients with advanced neuroblastoma. METHODS:PBT was conducted at 21 sites in 14 patients with neuroblastoma from 1984 to 2010. Most patients were difficult to treat with photon radiotherapy. Two and 6 patients were classified into stages 3 a...

journal_title：Radiation oncology (London, England)

authors： Oshiro Y,Mizumoto M,Okumura T,Sugahara S,Fukushima T,Ishikawa H,Nakao T,Hashimoto T,Tsuboi K,Ohkawa H,Kaneko M,Sakurai H

更新日期：2013-06-12 00:00:00

abstract：BACKGROUND:Until 50% of patients with renal cancer or melanoma, develop brain metastases during the course of their disease. Stereotactic radiotherapy has become a standard of care for patients with a limited number of brain metastases. Given the radioresistant nature of melanoma and renal cancer, optimization of the f...

journal_title：Radiation oncology (London, England)

authors： Lesueur P,Lequesne J,Barraux V,Kao W,Geffrelot J,Grellard JM,Habrand JL,Emery E,Marie B,Thariat J,Stefan D

更新日期：2018-07-28 00:00:00

abstract：BACKGROUND:Despite increasing clinical data suggest that internal mammary node (IMN) irradiation would improve local-regional control and overall survival in breast cancer, its role remains controversial due to increased risk of cardiac and pulmonary toxicity. The current study aims to determine the high risk areas of ...

journal_title：Radiation oncology (London, England)

authors： Wang Y,Qi W,Xu H,Zhang M,Han Y,Chen J,Xu C

更新日期：2019-11-21 00:00:00

abstract：:An ever-growing body of evidence has linked the gut microbiome with both the effectiveness and the toxicity of cancer therapies. Radiotherapy is an effective way to treat tumors, although large variations exist among patients in tumor radio-responsiveness and in the incidence and severity of radiotherapy-induced side ...

journal_title：Radiation oncology (London, England)

authors： Liu J,Liu C,Yue J

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:The primary objective of this research was to assess the relationship between FPs' knowledge of palliative radiotherapy (RT) and referral for palliative RT. METHODS:1001 surveys were sent to FPs who work in urban, suburban, and rural practices. Respondents were tested on their knowledge of palliative radiot...

journal_title：Radiation oncology (London, England)

authors： Olson RA,Lengoc S,Tyldesley S,French J,McGahan C,Soo J

更新日期：2012-05-18 00:00:00

abstract：BACKGROUND:68Ga-PSMA-PET-imaging has proven to be a highly sensitive and specific diagnostic element for patients with prostate cancer (PC). Does the standard clinical target volume (CTV) cover the majority of 68Ga-PSMA-PET detected lymph nodes (LNs) in a primary setting? METHODS:25 out of 159 patients with primary PC...

journal_title：Radiation oncology (London, England)

authors： Schiller K,Devecka M,Maurer T,Eiber M,Gschwend J,Schwaiger M,Combs SE,Habl G

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:The HyperArc VMAT (HA-VMAT) planning approach was newly developed to fulfill the demands of dose delivery for brain metastases stereotactic radiosurgery. We compared the dosimetric parameters of the HA-VMAT plan with those of the conventional VMAT (C-VMAT). MATERIAL AND METHODS:For 23 patients (1-4 brain metas...

journal_title：Radiation oncology (London, England)

authors： Ohira S,Ueda Y,Akino Y,Hashimoto M,Masaoka A,Hirata T,Miyazaki M,Koizumi M,Teshima T

更新日期：2018-01-29 00:00:00

abstract：BACKGROUND:To investigate patterns of failure and survival rates of elective irradiation of upper neck in N0 nasopharyngeal carcinoma patients. METHODS:From February 1996 to November 2002, 97 patients without cervical lymph node involvement were admitted for radiotherapy alone. Before treatment, each patient underwent...

journal_title：Radiation oncology (London, England)

authors： He X,Pan Z,Guo X,Ye M,Zhang Z,He S,Liu T

更新日期：2012-03-19 00:00:00

abstract：BACKGROUND:A new-generation low-energy linear accelerator (UNIQUE) was introduced in the clinical arena during 2009 by Varian Medical Systems. The world's first UNIQUE was installed at Oncology Institute of Southern Switzerland and put into clinical operation in June 2010. The aim of the present contribution was to rep...

journal_title：Radiation oncology (London, England)

authors： Clivio A,Nicolini G,Vanetti E,Fogliata A,Cozzi L

更新日期：2011-09-30 00:00:00

abstract：BACKGROUND:Helical irradiation of the total skin (HITS) was modified as simultaneous integrated boost (SIB)-helical arc radiotherapy of total skin (HEARTS) technique and applied to an acute myeloid leukemia (AML) patient with disseminated leukemia cutis. METHODS:The original HITS plan was revised for different regimen...

journal_title：Radiation oncology (London, England)

authors： Hsieh CH,Tien HJ,Yu YB,Wu YH,Shueng PW,Lu YF,Wang SY,Wang LY

更新日期：2019-01-28 00:00:00

abstract：BACKGROUND:Scanned ion beam therapy of intra-fractionally moving tumors requires motion mitigation. GSI proposed beam tracking and performed several experimental studies to analyse the dosimetric precision of the system for scanned carbon beams. METHODS:A beam tracking system has been developed and integrated in the s...

journal_title：Radiation oncology (London, England)

authors： Bert C,Gemmel A,Saito N,Chaudhri N,Schardt D,Durante M,Kraft G,Rietzel E

更新日期：2010-06-30 00:00:00

abstract：BACKGROUND:Gossypol, a naturally occurring polyphenolic compound has been identified as a small molecule inhibitor of anti-apoptotic Bcl-2 family proteins. It induces apoptosis in a wide range of tumor cell lines and enhances chemotherapy- and radiation-induced cytotoxicity both in vitro and in vivo. Bcl-2 and related ...

journal_title：Radiation oncology (London, England)

authors： Zerp SF,Stoter R,Kuipers G,Yang D,Lippman ME,van Blitterswijk WJ,Bartelink H,Rooswinkel R,Lafleur V,Verheij M

更新日期：2009-10-23 00:00:00

abstract：BACKGROUND:To retrospectively review the efficacy and organ preservation experience for muscle-invasive bladder cancer by trimodality therapy at our institution. METHODS:Between July 2004 and February 2012, seventy patients (M/F = 55/15; median age = 69 years) of lymph node negative localized muscle-invasive bladder c...

journal_title：Radiation oncology (London, England)

authors： Lee CY,Yang KL,Ko HL,Huang RY,Tsai PP,Chen MT,Lin YC,Hwang TI,Juang GD,Chi KH

更新日期：2014-09-24 00:00:00

abstract：BACKGROUND AND PURPOSE:Intensity modulated radiotherapy (IMRT) is a powerful tool, which might go a long way in reducing radiation doses to critical structures and thereby reduce long term morbidities.The purpose of this paper is to evaluate the impact of IMRT in reducing the dose to the critical normal tissues while m...

journal_title：Radiation oncology (London, England)

authors： Kataria T,Rawat S,Sinha SN,Garg C,Bhalla NK,Negi PS

更新日期：2006-08-29 00:00:00

abstract：BACKGROUND:Advanced non-small cell lung cancer (NSCLC) is an aggressive tumor that is treated with a combination of chemotherapy and radiation if the patient is not a candidate for surgery. Predictive biomarkers for response to radiotherapy are lacking in this patient population, making it a non-tailored therapy regime...

journal_title：Radiation oncology (London, England)

authors： Chakrabarti G

更新日期：2015-07-16 00:00:00

abstract：BACKGROUND:This study aimed to elucidate the influence of skin invasion in patients with recurrent head and neck cancer treated with re-irradiation using stereotactic radiotherapy. MATERIALS:We reviewed 104 patients treated using CyberKnife in four institutions. RESULTS:Nine cases of skin invasion were recognized (8....

journal_title：Radiation oncology (London, England)

authors： Yamazaki H,Ogita M,Himei K,Nakamura S,Suzuki G,Kotsuma T,Yoshida K,Yoshioka Y

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the potential dose reduction to the heart, left anterior descending (LAD) coronary artery and the ipsilateral lung for patients treated with tangential and locoregional radiotherapy for left-sided breast cancer with enhanced inspiration gating (EIG) compared to fr...

journal_title：Radiation oncology (London, England)

authors： Edvardsson A,Nilsson MP,Amptoulach S,Ceberg S

更新日期：2015-04-10 00:00:00

abstract：OBJECTIVE:The benefit of adjuvant radiotherapy (ART) for extrahepatic cholangiocarcinoma (EHCC) and gallbladder carcinoma (GBC) is unclear, with conflicting results from nonrandomized studies. We reported a meta-analysis to determine the impact of adjuvant radiotherapy on survival. METHODS:PubMed, EMBASE, Cochrane Lib...

journal_title：Radiation oncology (London, England)

authors： Ren B,Guo Q,Yang Y,Liu L,Wei S,Chen W,Tian Y

更新日期：2020-01-15 00:00:00

abstract：BACKGROUND:Renal atrophy is observed in an irradiated kidney. The aim of this study was to determine dose-volume histogram parameters and other factors that predict renal atrophy after 10-fraction stereotactic body radiotherapy (SBRT) for primary renal cell carcinoma (RCC). METHODS:A total of 14 patients (11 males, 3 ...

journal_title：Radiation oncology (London, England)

authors： Yamamoto T,Kadoya N,Takeda K,Matsushita H,Umezawa R,Sato K,Kubozono M,Ito K,Ishikawa Y,Kozumi M,Takahashi N,Katagiri Y,Onishi H,Jingu K

更新日期：2016-05-26 00:00:00

abstract：BACKGROUND:The objective of this investigation is to evaluate the outcomes and toxicity of carbon-ion re-irradiation (CIR) in patients with rare head and neck cancers (HNC). There is a paucity of data regarding treatment approaches in this patient cohort, which we aim to address in this work. METHODS:Thirty-two (n = 3...

journal_title：Radiation oncology (London, England)

authors： Held T,Windisch P,Akbaba S,Lang K,Farnia B,Liermann J,Bernhardt D,Plinkert P,Freudlsperger C,Rieken S,Herfarth K,Debus J,Adeberg S

更新日期：2019-11-12 00:00:00

abstract：BACKGROUND:Radiologic response of brain tumors is traditionally assessed according to the Macdonald criteria 10 weeks from the start of therapy. Because glioblastoma (GB) responds in days rather than weeks after boron neutron capture therapy (BNCT) that is a form of tumor-selective particle radiation, it is inconvenien...

journal_title：Radiation oncology (London, England)

authors： Hiramatsu R,Kawabata S,Furuse M,Miyatake S,Kuroiwa T

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:To explore the differences and correlations between the target volumes defined using preoperative prone diagnostic magnetic resonance imaging (MRI) and postoperative prone computed tomography (CT) simulation imaging based on deformable image registration (DIR) for external-beam partial breast irradiation (EB...

journal_title：Radiation oncology (London, England)

authors： Yu T,Li JB,Wang W,Xu M,Zhang YJ,Shao Q,Liu XJ,Xu L

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:We performed dosimetric comparisons between proton beam therapy and intensity modulated radiotherapy (IMRT) of intracranial germ cell tumors (ICGCTs) arising in various locations of the brain. MATERIALS:IMRT, passively scattered proton therapy (PSPT), and spot scanning proton therapy (SSPT) plans were perfo...

journal_title：Radiation oncology (London, England)

authors： Park J,Park Y,Lee SU,Kim T,Choi YK,Kim JY

更新日期：2015-06-26 00:00:00