Passive smoking and cardiorespiratory health in a general population in the west of Scotland.

abstract：OBJECTIVE:To investigate the effects of spinal cord stimulation on myocardial ischaemia, coronary blood flow, and myocardial oxygen consumption in angina pectoris induced by atrial pacing. DESIGN:The heart was paced to angina during a control phase and treatment with spinal cord stimulation. Blood samples were drawn f...

journal_title：BMJ (Clinical research ed.)

authors： Mannheimer C,Eliasson T,Andersson B,Bergh CH,Augustinsson LE,Emanuelsson H,Waagstein F

更新日期：1993-08-21 00:00:00

abstract：OBJECTIVES:To assess the acceptability of screening newborn boys for Duchenne muscular dystrophy. DESIGN:Screening is offered on the basis of informed consent in response to an information sheet entitled "A new test for baby boys--Do you want it?" The programme includes a prospective long term evaluation of family res...

journal_title：BMJ (Clinical research ed.)

authors： Bradley DM,Parsons EP,Clarke AJ

更新日期：1993-02-06 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of the anticoagulant fondaparinux in older acute medical inpatients at moderate to high risk of venous thromboembolism. DESIGN:Double blind randomised placebo controlled trial. SETTING:35 centres in eight countries. PARTICIPANTS:849 medical patients aged 60 or more admi...

journal_title：BMJ (Clinical research ed.)

authors： Cohen AT,Davidson BL,Gallus AS,Lassen MR,Prins MH,Tomkowski W,Turpie AG,Egberts JF,Lensing AW,ARTEMIS Investigators.

更新日期：2006-02-11 00:00:00

abstract：OBJECTIVE:To determine whether inhaled salmeterol, a new long acting inhaled beta adrenergic agonist, reduces nocturnal bronchoconstriction and improves sleep quality in patients with nocturnal asthma. DESIGN:Randomised, double blind, placebo controlled crossover study. SETTING:Hospital outpatient clinics in Edinburg...

journal_title：BMJ (Clinical research ed.)

authors： Fitzpatrick MF,Mackay T,Driver H,Douglas NJ

更新日期：1990-12-15 00:00:00

abstract：OBJECTIVE:To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical...

journal_title：BMJ (Clinical research ed.)

authors： Aune D,Sen A,Prasad M,Norat T,Janszky I,Tonstad S,Romundstad P,Vatten LJ

更新日期：2016-05-04 00:00:00

abstract：OBJECTIVE:To describe the progression of HIV disease in a haemophilic cohort and to show the influence of treatment. DESIGN:11 year longitudinal clinical and laboratory study. SETTING:A haemophilia centre. PATIENTS:111 patients infected with HIV during October 1979 to July 1985. MAIN OUTCOME MEASURES:Symptoms of HI...

journal_title：BMJ (Clinical research ed.)

authors： Lee CA,Phillips AN,Elford J,Janossy G,Griffiths P,Kernoff P

更新日期：1991-11-02 00:00:00

abstract：OBJECTIVE:To quantify an association between acute kidney injury and use of high potency statins versus low potency statins. DESIGN:Retrospective observational analysis of administrative databases, using nine population based cohort studies and meta-analysis. We performed as treated analyses in each database with a ne...

journal_title：BMJ (Clinical research ed.)

authors： Dormuth CR,Hemmelgarn BR,Paterson JM,James MT,Teare GF,Raymond CB,Lafrance JP,Levy A,Garg AX,Ernst P,Canadian Network for Observational Drug Effect Studies.

更新日期：2013-03-18 00:00:00

abstract：:Robots designed for surgery have three main advantages over humans. They have greater three dimensional spatial accuracy, are more reliable, and can achieve much greater precision. Although few surgical robots are yet in clinical trials one or two have advanced to the stage of seeking approval from the UK's Medical De...

journal_title：BMJ (Clinical research ed.)

authors： Buckingham RA,Buckingham RO

更新日期：1995-12-02 00:00:00

abstract：OBJECTIVE:To describe the time distribution of visits at night and to evaluate trends in night visits from 1982 to 1992. DESIGN:Analysis of a sample of one in 12 claim forms for night visits submitted over one year beginning 1 July 1991, and estimation of the number of night visits in previous years from data on payme...

journal_title：BMJ (Clinical research ed.)

authors： Salisbury C

更新日期：1993-03-20 00:00:00

abstract：OBJECTIVE:To determine whether failure to adequately adjust for a reported 40% misclassification of use of in vitro fertilisation (IVF) as reported in a Swedish study could have led to a false finding that folic acid increases dizygotic twinning. DESIGN:Modelling with population based data. SETTING:Swedish vital reco...

journal_title：BMJ (Clinical research ed.)

authors： Berry RJ,Kihlberg R,Devine O

更新日期：2005-04-09 00:00:00

abstract：:Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients' health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy, there are barriers to access for these t...

journal_title：BMJ (Clinical research ed.)

authors： Kay-Stacey M,Attarian H

更新日期：2016-07-06 00:00:00

abstract：OBJECTIVE:To analyse the risk of second primary cancers during long term follow up of patients with Hodgkin's disease. DESIGN:Cohort study. SETTING:The British National Lymphoma Investigation (a collaborative group of over 60 participating centres in Britain treating lymphomas). PATIENTS:2846 patients first treated ...

journal_title：BMJ (Clinical research ed.)

authors： Swerdlow AJ,Douglas AJ,Hudson GV,Hudson BV,Bennett MH,MacLennan KA

更新日期：1992-05-02 00:00:00

abstract：OBJECTIVE:To compare four potential screening strategies, and subsequent interventions, for the prevention and treatment of type 2 diabetes: (a) screening for type 2 diabetes to enable early detection and treatment, (b) screening for type 2 diabetes and impaired glucose tolerance, intervening with lifestyle interventio...

journal_title：BMJ (Clinical research ed.)

authors： Gillies CL,Lambert PC,Abrams KR,Sutton AJ,Cooper NJ,Hsu RT,Davies MJ,Khunti K

更新日期：2008-05-24 00:00:00

abstract：OBJECTIVE:To examine the relation between diameters of the retinal arterioles and 10 year incidence of hypertension. DESIGN:Population based prospective cohort study. SETTING:Beaver Dam eye study. PARTICIPANTS:2451 normotensive people aged 43 to 84 years. MAIN OUTCOME MEASURES:Diameters of retinal arterioles and ve...

journal_title：BMJ (Clinical research ed.)

authors： Wong TY,Shankar A,Klein R,Klein BE,Hubbard LD

更新日期：2004-07-10 00:00:00

abstract：OBJECTIVE:To study delays between sending referral letters and the outpatient appointment and to assess the content of referral and reply letters, their educational value, and the extent to which questions asked are answered by reply letters. DESIGN:Retrospective review of referrals to 16 consultant orthopaedic surgeo...

journal_title：BMJ (Clinical research ed.)

authors： Jacobs LG,Pringle MA

更新日期：1990-09-08 00:00:00

abstract：OBJECTIVES:To audit services for prenatal diagnosis for haemoglobin disorders in the United Kingdom. DESIGN:Comparison of the annual number of cases recorded in a United Kingdom register of prenatal diagnoses for haemoglobin disorders, with the annual number of pregnancies at risk of these disorders, by ethnic group a...

journal_title：BMJ (Clinical research ed.)

authors： Modell B,Petrou M,Layton M,Varnavides L,Slater C,Ward RH,Rodeck C,Nicolaides K,Gibbons S,Fitches A,Old J

更新日期：1997-09-27 00:00:00

abstract：OBJECTIVES:To examine how insurance companies assess proposals for life assurance from applicants with raised cholesterol concentrations and to determine the excess mortality rating applied. DESIGN:Survey of 49 companies underwriting term life assurance. SETTING:United Kingdom. SUBJECTS:Four fictional men aged 30 se...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D

更新日期：1991-04-13 00:00:00

abstract：OBJECTIVES:To identify the frequency with which antibiotics are prescribed in the absence of a documented indication in the ambulatory care setting, to quantify the potential effect on assessments of appropriateness of antibiotics, and to understand patient, provider, and visit level characteristics associated with ant...

journal_title：BMJ (Clinical research ed.)

authors： Ray MJ,Tallman GB,Bearden DT,Elman MR,McGregor JC

更新日期：2019-12-11 00:00:00

abstract：:Eleven euthyroid patients with severe Graves' eye disease were treated with intravenous methylprednisolone and followed up for six months or more by ophthalmological assessment, orbital computed tomography (CT), photographs, and antibody measurements. Papilloedema resolved in the single patient in whom it was present;...

journal_title：BMJ (Clinical research ed.)

authors： Kendall-Taylor P,Crombie AL,Stephenson AM,Hardwick M,Hall K

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To investigate the long term effectiveness of integrated disease management delivered in primary care on quality of life in patients with chronic obstructive pulmonary disease (COPD) compared with usual care. DESIGN:24 month, multicentre, pragmatic cluster randomised controlled trial SETTING:40 general prac...

journal_title：BMJ (Clinical research ed.)

authors： Kruis AL,Boland MR,Assendelft WJ,Gussekloo J,Tsiachristas A,Stijnen T,Blom C,Sont JK,Rutten-van Mölken MP,Chavannes NH

更新日期：2014-09-10 00:00:00

abstract：OBJECTIVE:To determine the long term effects of antibiotic treatment for acute otitis media in young children. DESIGN:Prospective three year follow-up study within the framework of a primary care based, double blind, randomised, placebo controlled trial. SETTING:53 general practices in the Netherlands. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bezáková N,Damoiseaux RA,Hoes AW,Schilder AG,Rovers MM

更新日期：2009-06-30 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00

abstract：OBJECTIVE:To describe mortality by suicide and other causes of death in a group of patients who attempted suicide, and to identify predictive factors. DESIGN:10 year follow up study based on records of suicide attempters in 1980. SETTING:Poisoning treatment centre at a general hospital. SUBJECTS:974 patients aged 15...

journal_title：BMJ (Clinical research ed.)

authors： Nordentoft M,Breum L,Munck LK,Nordestgaard AG,Hunding A,Laursen Bjaeldager PA

更新日期：1993-06-19 00:00:00

abstract：OBJECTIVE:To determine whether the intervention of a physiotherapist improved mobility in patients seen more than one year after stroke. DESIGN:Randomised crossover trial comparing two groups offered intervention by a physiotherapist, one immediately after entry into the trial and the other after a delay of three mont...

journal_title：BMJ (Clinical research ed.)

authors： Wade DT,Collen FM,Robb GF,Warlow CP

更新日期：1992-03-07 00:00:00

abstract：OBJECTIVES:Confirmation of breakthroughs in three different malaria chemoprophylactic regimens (chloroquine 300 mg weekly and proguanil 100 mg daily; chloroquine 300 mg weekly and proguanil 200 mg daily; proguanil 200 mg daily) and assessment of compliance. DESIGN:Prospective, randomised multicentre trial. SETTING:Fi...

journal_title：BMJ (Clinical research ed.)

authors： Wetsteyn JC,de Geus A

更新日期：1993-10-23 00:00:00

abstract：OBJECTIVES:To investigate whether the use of graduated compression stockings (GCS) offers any adjuvant benefit when pharmaco-thromboprophylaxis is used for venous thromboembolism prophylaxis in patients undergoing elective surgery. DESIGN:Open, multicentre, randomised, controlled, non-inferiority trial. SETTING:Seven...

journal_title：BMJ (Clinical research ed.)

authors： Shalhoub J,Lawton R,Hudson J,Baker C,Bradbury A,Dhillon K,Everington T,Gohel MS,Hamady Z,Hunt BJ,Stansby G,Warwick D,Norrie J,Davies AH,GAPS trial investigators.

更新日期：2020-05-13 00:00:00

abstract：:Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate. Hepatorenal syndrome is diagnosed when kidney function is reduced but evidence of intrinsic kidney disease, such as hematuria, proteinu...

journal_title：BMJ (Clinical research ed.)

authors： Simonetto DA,Gines P,Kamath PS

更新日期：2020-09-14 00:00:00

abstract：PROBLEM:Despite widespread acceptance of the Ottawa ankle rules for assessment of acute ankle injuries, their application varies considerably. DESIGN:Before and after study. BACKGROUND AND SETTING:Emergency departments of a tertiary teaching hospital and a community hospital in Australia. KEY MEASURES FOR IMPROVEMEN...

journal_title：BMJ (Clinical research ed.)

authors： Bessen T,Clark R,Shakib S,Hughes G

更新日期：2009-08-12 00:00:00

abstract：OBJECTIVE:To examine the predictors of long term outcome for patients with the chronic fatigue syndrome. DESIGN:Cohort study. SUBJECTS:139 subjects previously enrolled in two treatment trials; 103 (74%) were reassessed a mean of 3.2 years after start of the trials. SETTING:University hospital referral centre. MAIN ...

journal_title：BMJ (Clinical research ed.)

authors： Wilson A,Hickie I,Lloyd A,Hadzi-Pavlovic D,Boughton C,Dwyer J,Wakefield D

更新日期：1994-03-19 00:00:00

abstract：OBJECTIVE:To describe temporal trends in the time interval between first and second attempts at defibrillation and the association between this time interval and outcomes in patients with persistent ventricular tachycardia or ventricular fibrillation (VT/VF) arrest in hospital. DESIGN:Retrospective cohort study SETTI...

journal_title：BMJ (Clinical research ed.)

authors： Bradley SM,Liu W,Chan PS,Nallamothu BK,Grunwald GK,Self A,Sasson C,Varosy PD,Anderson ML,Schneider PM,Ho PM,American Heart Association’s Get With The Guidelines-Resuscitation Investigators.

更新日期：2016-04-06 00:00:00