Altered calcitonin gene in a young patient with osteoporosis.

abstract：OBJECTIVE:To re-evaluate the causal effect of interpregnancy interval on adverse birth outcomes, on the basis that previous studies relying on between mother comparisons may have inadequately adjusted for confounding by maternal risk factors. DESIGN:Retrospective cohort study using conditional logistic regression (mat...

journal_title：BMJ (Clinical research ed.)

authors： Ball SJ,Pereira G,Jacoby P,de Klerk N,Stanley FJ

更新日期：2014-07-23 00:00:00

abstract：OBJECTIVE:To establish whether there is evidence of the efficacy of homoeopathy from controlled trials in humans. DESIGN:Criteria based meta-analysis. Assessment of the methodological quality of 107 controlled trials in 96 published reports found after an extensive search. Trials were scored using a list of predefined...

journal_title：BMJ (Clinical research ed.)

authors： Kleijnen J,Knipschild P,ter Riet G

更新日期：1991-02-09 00:00:00

abstract：:In Oregon, Planned Parenthood and a group of physicians who perform abortions have filed a civil suit against several anti-abortion groups individuals. The suit seeks $200 million in damages and an injunction to bar the defendants from posting information on the Internet that threatens the lives and well-being of the...

journal_title：BMJ (Clinical research ed.)

authors： Charatan F

更新日期：1999-01-23 00:00:00

abstract：OBJECTIVE:To determine patient, institution, and machine characteristics that contribute to variation in radiation doses used for computed tomography (CT). DESIGN:Prospective cohort study. SETTING:Data were assembled and analyzed from the University of California San Francisco CT International Dose Registry. PARTICI...

journal_title：BMJ (Clinical research ed.)

authors： Smith-Bindman R,Wang Y,Chu P,Chung R,Einstein AJ,Balcombe J,Cocker M,Das M,Delman BN,Flynn M,Gould R,Lee RK,Yellen-Nelson T,Schindera S,Seibert A,Starkey J,Suntharalingam S,Wetter A,Wildberger JE,Miglioretti DL

更新日期：2019-01-02 00:00:00

abstract：OBJECTIVE:To assess the impact of construction of microdams on the incidence of malaria in nearby communities in terms of possibly increasing peak incidence and prolonging transmission. DESIGN:Four quarterly cycles of malaria incidence surveys, each taking 30 days, undertaken in eight at risk communities close to dams...

journal_title：BMJ (Clinical research ed.)

authors： Ghebreyesus TA,Haile M,Witten KH,Getachew A,Yohannes AM,Yohannes M,Teklehaimanot HD,Lindsay SW,Byass P

更新日期：1999-09-11 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of two mechanical methods of blood conservation in reducing the need for allogeneic red blood cells or coagulation products during cardiac surgery. DESIGN:Randomised controlled trial. SETTING:Regional cardiac centre in a teaching hospital in Southampton. PARTICIPANTS:263 adults ...

journal_title：BMJ (Clinical research ed.)

authors： McGill N,O'Shaughnessy D,Pickering R,Herbertson M,Gill R

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To study the comparative importance of environment and genes in the development of islet cell autoimmunity associated with insulin dependent diabetes mellitus. DESIGN:Population based study of diabetic twins. SETTING:Danish population. SUBJECTS:18 monozygotic and 36 dizygotic twin pairs with one or both pa...

journal_title：BMJ (Clinical research ed.)

authors： Petersen JS,Kyvik KO,Bingley PJ,Gale EA,Green A,Dyrberg T,Beck-Nielsen H

更新日期：1997-05-31 00:00:00

abstract：OBJECTIVES:To evaluate the long term effects of perioperative beta blockade on mortality and cardiac morbidity in patients with diabetes undergoing major non-cardiac surgery. DESIGN:Randomised placebo controlled and blinded multicentre trial. Analyses were by intention to treat. SETTING:University anaesthesia and sur...

journal_title：BMJ (Clinical research ed.)

authors： Juul AB,Wetterslev J,Gluud C,Kofoed-Enevoldsen A,Jensen G,Callesen T,Nørgaard P,Fruergaard K,Bestle M,Vedelsdal R,Miran A,Jacobsen J,Roed J,Mortensen MB,Jørgensen L,Jørgensen J,Rovsing ML,Petersen PL,Pott F,Haas M,

更新日期：2006-06-24 00:00:00

abstract：OBJECTIVE:To evaluate the outcome of liver transplantation in patients with alcoholic cirrhosis with respect to selection criteria, survival, and evidence suggesting a return to harmful drinking. DESIGN:Nine year retrospective study. SETTING:Cambridge and King's College Hospital liver transplant programme. SUBJECTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bird GL,O'Grady JG,Harvey FA,Calne RY,Williams R

更新日期：1990-07-07 00:00:00

abstract：:Recent changes in the Russian government introduced by Boris Yeltsin include the appointment of Eduard Nechaev as health minister at the beginning of this year. The appointment received little publicity in the West, although his predecessor was sacked after only one year for failing to make any effort to improve healt...

journal_title：BMJ (Clinical research ed.)

authors： Ryan M

更新日期：1993-04-03 00:00:00

abstract：OBJECTIVE:To examine the absolute risks or benefits on cancer associated with oral contraception, using incident data. DESIGN:Inception cohort study. SETTING:Royal College of General Practitioners' oral contraception study. PARTICIPANTS:Directly standardised data from the Royal College of General Practitioners' oral...

journal_title：BMJ (Clinical research ed.)

authors： Hannaford PC,Selvaraj S,Elliott AM,Angus V,Iversen L,Lee AJ

更新日期：2007-09-29 00:00:00

abstract：OBJECTIVES:To evaluate the evidence for strategies to prevent falls or fractures in residents in care homes and hospital inpatients and to investigate the effect of dementia and cognitive impairment. DESIGN:Systematic review and meta-analyses of studies grouped by intervention and setting (hospital or care home). Meta...

journal_title：BMJ (Clinical research ed.)

authors： Oliver D,Connelly JB,Victor CR,Shaw FE,Whitehead A,Genc Y,Vanoli A,Martin FC,Gosney MA

更新日期：2007-01-13 00:00:00

abstract：OBJECTIVE:To compare blood pressure control, satisfaction, and adherence to drug treatment in patients with treated hypertension followed up by their family physicians either every three months or every six months for three years. DESIGN:Randomised equivalence clinical trial. Settings 50 family practices in south east...

journal_title：BMJ (Clinical research ed.)

authors： Birtwhistle RV,Godwin MS,Delva MD,Casson RI,Lam M,MacDonald SE,Seguin R,Rühland L

更新日期：2004-01-24 00:00:00

abstract：STUDY QUESTION:Does maternal smoking during pregnancy and exposure of infants to tobacco smoke at age 4 months increase the risk of caries in deciduous teeth? METHODS:Population based retrospective cohort study of 76 920 children born between 2004 and 2010 in Kobe City, Japan who received municipal health check-ups at...

journal_title：BMJ (Clinical research ed.)

authors： Tanaka S,Shinzawa M,Tokumasu H,Seto K,Tanaka S,Kawakami K

更新日期：2015-10-21 00:00:00

abstract：:A total of 22,552 workers employed by the Atomic Weapons Establishment between 1951 and 1982 were followed up for an average of 18.6 years. Of the 3115 who died, 865 (28%) died of cancer. Mortality was 23% lower than the national average for all causes of death and 18% lower for cancer. These low rates were consistent...

journal_title：BMJ (Clinical research ed.)

authors： Beral V,Fraser P,Carpenter L,Booth M,Brown A,Rose G

更新日期：1988-09-24 00:00:00

abstract：OBJECTIVES:To compare the clinical and cost effectiveness of total hip arthroplasty with resurfacing arthroplasty in patients with severe arthritis of the hip. DESIGN:Single centre, two arm, parallel group, assessor blinded, randomised controlled trial with 1:1 treatment allocation. SETTING:One large teaching hospita...

journal_title：BMJ (Clinical research ed.)

authors： Costa ML,Achten J,Parsons NR,Edlin RP,Foguet P,Prakash U,Griffin DR,Young Adult Hip Arthroplasty Team.

更新日期：2012-04-19 00:00:00

abstract：OBJECTIVE:To assess evidence from randomised clinical trials about the effectiveness of extracts of Boswellia serrata (frankincense). DESIGN:Systematic review. DATA SOURCES:Electronic searches on Medline, Embase, Cinahl, Amed, and Cochrane Library. Hand searches of conference proceedings, bibliographies, and departme...

journal_title：BMJ (Clinical research ed.)

authors： Ernst E

更新日期：2008-12-17 00:00:00

abstract：OBJECTIVE:To assess whether occupational exposure among commercial airline cabin attendants are associated with risk of cancer. DESIGN:Record linkage study. SETTING:Finland. SUBJECTS-1577 female and 187 male cabin attendants who had worked for the Finnish airline companies. MAIN OUTCOME MEASURE:Standardised incidenc...

journal_title：BMJ (Clinical research ed.)

authors： Pukkala E,Auvinen A,Wahlberg G

更新日期：1995-09-09 00:00:00

abstract：OBJECTIVE:To examine the role of peak bone mass and subsequent postmenopausal bone loss in the development of osteoporosis and the reliability of identifying women at risk from one bone mass measurement and one biochemical assessment of the future bone loss. DESIGN:Population based study. SETTING:Outpatient clinic fo...

journal_title：BMJ (Clinical research ed.)

authors： Hansen MA,Overgaard K,Riis BJ,Christiansen C

更新日期：1991-10-19 00:00:00

abstract：:The disease management approach to patient care seeks to coordinate resources across the healthcare delivery system. The growing interest in evidence based medicine and outcomes, and a commitment to integrated care across the primary, secondary, and community care sectors, all contribute to making disease management a...

journal_title：BMJ (Clinical research ed.)

authors： Hunter DJ,Fairfield G

更新日期：1997-07-05 00:00:00

abstract：OBJECTIVE:To assess predictors of mortality in a population of people prescribed methadone. DESIGN:Retrospective cohort study. SETTING:Geographically defined population in Tayside, Scotland. PARTICIPANTS:2378 people prescribed and dispensed liquid methadone between January 1993 and February 2004. MAIN OUTCOME MEASU...

journal_title：BMJ (Clinical research ed.)

authors： McCowan C,Kidd B,Fahey T

更新日期：2009-06-16 00:00:00

abstract：:The opportunities for international public health collaboration through joint business ventures between the USSR and Western nations, an arrangement that would benefit the public, industry, and the medical community, are discussed. Evidence indicates that the state of health of the Soviet population is declining rapi...

journal_title：BMJ (Clinical research ed.)

authors： Gellert GA,Kaznady SI

更新日期：1991-03-16 00:00:00

abstract：OBJECTIVE:To identify the factors associated with diabetic ketoacidosis at diagnosis of type 1 diabetes in children and young adults. DESIGN:Systematic review. DATA SOURCES:PubMed, EMBASE, Web of Science, Scopus, and Cinahl and article reference lists. STUDY SELECTION:Cohort studies including unselected groups of ch...

journal_title：BMJ (Clinical research ed.)

authors： Usher-Smith JA,Thompson MJ,Sharp SJ,Walter FM

更新日期：2011-07-07 00:00:00

abstract：OBJECTIVE:To determine the long term effects of antibiotic treatment for acute otitis media in young children. DESIGN:Prospective three year follow-up study within the framework of a primary care based, double blind, randomised, placebo controlled trial. SETTING:53 general practices in the Netherlands. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bezáková N,Damoiseaux RA,Hoes AW,Schilder AG,Rovers MM

更新日期：2009-06-30 00:00:00

abstract：OBJECTIVE:To investigate the effect of watching different types of video on energy expenditure. DESIGN:Randomised study assessing a "pleasant," an "amusing," an "exciting," and no video film clips. SUBJECTS:12 volunteers who did not know the purpose of the study. MAIN OUTCOME MEASURES:Changes in energy expenditure, ...

journal_title：BMJ (Clinical research ed.)

authors： Cooper BG,Matthews JN,Alberti KG

更新日期：1995-12-23 00:00:00

abstract：OBJECTIVE:To determine whether inhaled salmeterol, a new long acting inhaled beta adrenergic agonist, reduces nocturnal bronchoconstriction and improves sleep quality in patients with nocturnal asthma. DESIGN:Randomised, double blind, placebo controlled crossover study. SETTING:Hospital outpatient clinics in Edinburg...

journal_title：BMJ (Clinical research ed.)

authors： Fitzpatrick MF,Mackay T,Driver H,Douglas NJ

更新日期：1990-12-15 00:00:00

abstract：:This paper summarizes the key findings of a U.S. study of 48 primary care physicians acting as gatekeepers in a large health maintenance organization to determine the effects of their cost containment role on the doctor patient relationship. Taylor highlights some of the findings and conclusions that he believes are ...

journal_title：BMJ (Clinical research ed.)

authors： Taylor TR

更新日期：1989-11-25 00:00:00

abstract：:An increase in the incidence of cardiovascular disease has generally been observed in postmenopausal women, but there have been few studies of the association between menopausal state and atherosclerosis. In this study 294 premenopausal and 319 postmenopausal women aged 45 to 55 were examined radiographically for calc...

journal_title：BMJ (Clinical research ed.)

authors： Witteman JC,Grobbee DE,Kok FJ,Hofman A,Valkenburg HA

更新日期：1989-03-11 00:00:00

abstract：:A committee of French bishops has contradicted the Vatican's condemnation of all methods of contraception by acknowledging that condom use may be necessary in order to prevent the spread of HIV and protect against AIDS. The Social Commission of the French Episcopate made this statement in a book entitled AIDS: Societ...

journal_title：BMJ (Clinical research ed.)

authors： Dorozynski A

更新日期：1996-02-24 00:00:00

abstract：:The instrument through which a commissioner purchases health services from a provider is, as in other walks of life, a contract, so considerable importance has been attached by the NHS Executive to the contracting mechanism. A contract should in theory influence the quality of the service provided, but they are in man...

journal_title：BMJ (Clinical research ed.)

authors： Hopkins A,Solomon JK

更新日期：1996-08-24 00:00:00