Genetic signature of differential sensitivity to stevioside in the Italian population.

abstract：:There is a growing interest in assessing dietary intake more accurately across different population groups, and biomarkers have emerged as a complementary tool to replace traditional dietary assessment methods. The purpose of this study was to conduct a systematic review of the literature available and evaluate the ap...

journal_title：Genes & nutrition

authors： Sri Harsha PSC,Wahab RA,Garcia-Aloy M,Madrid-Gambin F,Estruel-Amades S,Watzl B,Andrés-Lacueva C,Brennan L

更新日期：2018-09-10 00:00:00

abstract：:Breast cancer is the second most frequent cancer affecting women worldwide after lung cancer. The toxicity factor associated with synthetic drugs has turned the attention toward natural compounds as the primary focus of interest as anticancer agents. Vitamin E derivatives consisting of the well-established tocopherols...

journal_title：Genes & nutrition

authors： Nesaretnam K,Meganathan P,Veerasenan SD,Selvaduray KR

更新日期：2012-01-01 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR), riboflavin-dependent enzymes, participate in homocysteine metabolism. Reported effects of riboflavin status on the association between the MTHFR 677C>T polymorphism and homocysteine vary, and the effects of the MTRR 66A>G or MTRR 524...

journal_title：Genes & nutrition

authors： García-Minguillán CJ,Fernandez-Ballart JD,Ceruelo S,Ríos L,Bueno O,Berrocal-Zaragoza MI,Molloy AM,Ueland PM,Meyer K,Murphy MM

更新日期：2014-11-01 00:00:00

abstract：:While the effects of chronic ethanol consumption on liver have been well studied and documented, its effect on the cardiovascular system is bimodal. Thus, moderate drinking in many population studies is related to lower prevalence of coronary artery disease (CAD). In contrast, heavy drinking correlates with higher pre...

journal_title：Genes & nutrition

authors： Lakshman R,Garige M,Gong M,Leckey L,Varatharajalu R,Zakhari S

更新日期：2010-06-01 00:00:00

abstract：:It is widely accepted that metabolic disorders, such as obesity, are closely linked to lifestyle and diet. Recently, the central role played by the intestinal microbiota in human metabolism and in progression of metabolic disorders has become evident. In this context, animal studies and human trials have demonstrated ...

journal_title：Genes & nutrition

authors： Duranti S,Ferrario C,van Sinderen D,Ventura M,Turroni F

更新日期：2017-06-15 00:00:00

abstract：:Multiple factors have been implicated in the age-related declines in brain function. Thus, it is unlikely that modulating only a single factor will be effective at slowing this decline. A better approach is to identify small molecules that have multiple biological activities relevant to the maintenance of brain functi...

journal_title：Genes & nutrition

authors： Maher P

更新日期：2009-12-01 00:00:00

abstract：:Vitamin C is known to protect mucosal tissues from oxidative stress and inhibit nitrosamine formation in the stomach. High consumption of fruits, particularly citrus, and higher circulating vitamin C concentrations may be inversely associated with gastric cancer (GC) risk. We investigated 20 polymorphisms in vitamin C...

journal_title：Genes & nutrition

authors： Duell EJ,Lujan-Barroso L,Llivina C,Muñoz X,Jenab M,Boutron-Ruault MC,Clavel-Chapelon F,Racine A,Boeing H,Buijsse B,Canzian F,Johnson T,Dalgård C,Overvad K,Tjønneland A,Olsen A,Sánchez SC,Sánchez-Cantalejo E,Huerta JM

更新日期：2013-11-01 00:00:00

abstract：:Low plasma levels of high-density lipoprotein cholesterol (HDL-C) are identified as a risk factor for cardiovascular disease (CVD). Sexual dimorphism, however, is widely reported in both HDL-C and CVD, with the underlying explanations of these sexual differences not fully understood. HDL-C is a complex trait influence...

journal_title：Genes & nutrition

authors： Mosher MJ,Lange LA,Howard BV,Lee ET,Best LG,Fabsitz RR,Maccluer JW,North KE

更新日期：2008-07-01 00:00:00

abstract：:Type 2 diabetes (T2D) has become an increasingly challenging health burden due to its high morbidity, mortality, and heightened prevalence worldwide. Although dietary and nutritional imbalances have long been recognized as key risk factors for T2D, the underlying mechanisms remain unclear. The advent of nutritional sy...

journal_title：Genes & nutrition

authors： Zhao Y,Barrere-Cain RE,Yang X

更新日期：2015-09-01 00:00:00

abstract：:Phytosterol (PS) intake may be used for hypercholesterolaemia in some groups although the presence of non-responders is well known. Carotenoids and PS/cholesterol may compete for the same transporters during absorption. As part of a randomized, double-blind, crossover, multiple-dose supplementation study with β-crypto...

journal_title：Genes & nutrition

authors： Granado-Lorencio F,de Las Heras L,Millán CS,Garcia-López FJ,Blanco-Navarro I,Pérez-Sacristán B,Domínguez G

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Obesity is characterized by low-grade chronic inflammation and an excess of adipose tissue. The ASC gene encodes a protein that is part of the NLRP3 inflammasome, a cytosolic multiprotein complex that is associated with inflammation and metabolic alterations. To our knowledge, there is no evidence regarding ...

journal_title：Genes & nutrition

authors： Barrón-Cabrera E,González-Becerra K,Rosales-Chávez G,Mora-Jiménez A,Hernández-Cañaveral I,Martínez-López E

更新日期：2020-08-27 00:00:00

abstract：:Genetic variation in bitter taste receptors, such as hTAS2R38, may affect food preferences and intake. The aim of the present study was to investigate the association between bitter taste receptor haplotypes and the consumption of vegetables, fruits, berries and sweet foods among an adult Finnish population. A cross-s...

journal_title：Genes & nutrition

authors： Sandell M,Hoppu U,Mikkilä V,Mononen N,Kähönen M,Männistö S,Rönnemaa T,Viikari J,Lehtimäki T,Raitakari OT

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNAs involved in the modulation of gene expression and in the control of numerous cell functions. Alterations of miRNA patterns frequently occur in cancer and metabolic disorders, including obesity. Recent studies showed remarkable stability of miRNAs in both plasma an...

journal_title：Genes & nutrition

authors： Iacomino G,Russo P,Stillitano I,Lauria F,Marena P,Ahrens W,De Luca P,Siani A

更新日期：2016-03-21 00:00:00

abstract：:In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been the object of intensive research. miRNAs have emerged as key mediators of metabolic processes, playing crucial roles in maintaining/altering physiological processes, including energy balance and metabolic homeostasis. Altered miRNAs ...

journal_title：Genes & nutrition

authors： Iacomino G,Siani A

更新日期：2017-09-25 00:00:00

abstract：BACKGROUND:Methionine, a central molecule in one-carbon metabolism, is an essential amino acid required for normal growth and development. Despite its importance to biological systems, methionine is toxic when administered at supra-physiological levels. The aim of this study was to investigate the effects of short-term...

journal_title：Genes & nutrition

authors： Miousse IR,Pathak R,Garg S,Skinner CM,Melnyk S,Pavliv O,Hendrickson H,Landes RD,Lumen A,Tackett AJ,Deutz NEP,Hauer-Jensen M,Koturbash I

更新日期：2017-09-06 00:00:00

abstract：:The aim of this study was to examine the relationship between the L55M and Q192R paraoxonase (PON1) polymorphisms and obesity in a population of adult Mexican workers. The study population included 127 adult individuals from the Universidad Autónoma del Estado de Morelos, ranging in age from 20 to 56 years and represe...

journal_title：Genes & nutrition

authors： Martínez-Salazar MF,Almenares-López D,García-Jiménez S,Sánchez-Alemán MA,Juantorena-Ugás A,Ríos C,Monroy-Noyola A

更新日期：2011-11-01 00:00:00

abstract：:Personalized nutrition has the potential to enhance individual health control. It could be seen as a means to strengthen people's autonomy as they learn more about their personal health risks, and receive dietary advice accordingly. We examine in what sense personalized nutrition strengthens or weakens individual auto...

journal_title：Genes & nutrition

authors： Nordström K,Juth N,Kjellström S,Meijboom FL,Görman U,Food4Me project.

更新日期：2013-07-01 00:00:00

abstract：Background:The neurodegenerative disorder Alzheimer's disease is caused by the accumulation of toxic aggregates of β-amyloid in the human brain. On the one hand, hyperhomocysteinemia has been shown to be a risk factor for cognitive decline in Alzheimer's disease. On the other hand, betaine has been demonstrated to atte...

journal_title：Genes & nutrition

authors： Leiteritz A,Dilberger B,Wenzel U,Fitzenberger E

更新日期：2018-07-27 00:00:00

abstract：BACKGROUND:The ability to digest lactose after weaning, namely, lactase persistence (LP), is encoded by polymorphisms in the MCM6 gene and varies widely in frequency among different human populations. Although, evolution of LP-related genetic variants was investigated in many groups of Sub-Saharan African, Middle Easte...

journal_title：Genes & nutrition

authors： Ben Halima Y,Kefi R,Sazzini M,Giuliani C,De Fanti S,Nouali C,Nagara M,Mengozzi G,Elouej S,Abid A,Jamoussi H,Chouchane L,Romeo G,Abdelhak S,Luiselli D

更新日期：2017-08-24 00:00:00

abstract：:Recent immunohistochemical characterization of the copper transport protein, Ctr1, reported enriched levels in mouse choroid plexus, and enhancement by copper deficiency. To extend and confirm this, experiments were conducted with Holtzman rats. Following perinatal copper deficiency there was an 80% reduction in brain...

journal_title：Genes & nutrition

authors： Gybina AA,Prohaska JR

更新日期：2006-03-01 00:00:00

abstract：:There is growing interest in the potential health benefits of diets that involve regular periods of fasting. While animal studies have provided compelling evidence that feeding patterns such as alternate-day fasting can increase longevity and reduce incidence of many chronic diseases, the evidence from human studies i...

journal_title：Genes & nutrition

authors： Elliott RM,de Roos B,Duthie SJ,Bouwman FG,Rubio-Aliaga I,Crosley LK,Mayer C,Polley AC,Heim C,Coort SL,Evelo CT,Mulholland F,Daniel H,Mariman EC,Johnson IT

更新日期：2014-11-01 00:00:00

abstract：:Phytoestrogens are naturally occurring plantderived polyphenols with estrogenic potency. They are ubiquitous in diet and therefore, generally consumed. Among Europeans, the diet is rich in multiple putative phytoestrogens including flavonoids, tannins, stilbenoids, and lignans. These compounds have been suggested to p...

journal_title：Genes & nutrition

authors： Saarinen NM,Bingham C,Lorenzetti S,Mortensen A,Mäkelä S,Penttinen P,Sørensen IK,Valsta LM,Virgili F,Vollmer G,Wärri A,Zierau O

更新日期：2006-09-01 00:00:00

abstract：Background:We investigated whether the long-term consumption of a symbiotic formulation with Lactobacillus fermentum (probiotic) and β-glucan from cauliflower mushroom (prebiotic) would delay the progression of post-menopausal symptoms in ovariectomized (OVX) rats and explored their mechanisms of action, including chan...

journal_title：Genes & nutrition

authors： Jeong SY,Kang S,Hua CS,Ting Z,Park S

更新日期：2017-11-09 00:00:00

abstract：:The suitability of C. elegans as a model for the question of nutritional science is a controversial topic. The discussion makes clear that C. elegans is its own best model for revealing, via genetic approaches, biological principles of nutritional behavior, and the biochemical function of vitamins. In this case, the m...

journal_title：Genes & nutrition

authors： Gottschling DC,Döring F

更新日期：2019-01-09 00:00:00

abstract：:A large number of genome-wide association studies, transferability studies, and candidate gene studies performed in diverse populations around the world have identified gene variants that are associated with common human obesity. The mounting evidence suggests that these obesity gene variants interact with multiple en...

journal_title：Genes & nutrition

authors： Castillo JJ,Orlando RA,Garver WS

更新日期：2017-10-30 00:00:00

abstract：:Folic acid is the key one-carbon donor required for de novo nucleotide and methionine synthesis. Its deficiency is associated with megaloblastic anemia, cancer and various complications of pregnancy. However, its supplementation results in reduction of neural tube defects and prevention of several types of cancer. The...

journal_title：Genes & nutrition

authors： Thakur S,Thakur SD,Wani NA,Kaur J

更新日期：2014-01-01 00:00:00

abstract：:The nutraceutical benefits of β-sitosterol (SIT) are well documented. The present study investigated the in vitro effects of SIT on adipogenesis, glucose transport, and lipid mobilization in rat adipocytes. Primary cultures of rat preadipocytes and differentiated adipocytes were used in this study. Glucose uptake was ...

journal_title：Genes & nutrition

authors： Chai JW,Lim SL,Kanthimathi MS,Kuppusamy UR

更新日期：2011-05-01 00:00:00

abstract：:Functional polymorphisms in endogenous antioxidant defense genes including manganese superoxide dismutase (MnSOD), catalase (CAT), and glutathione peroxidase (GPX-1) have been linked with risk of cancer at multiple sites. Although it is presumed that these germline variants impact disease risk by altering the host's a...

journal_title：Genes & nutrition

authors： Al-Alem U,Gann PH,Dahl J,van Breemen RB,Mistry V,Lam PM,Evans MD,Van Horn L,Wright ME

更新日期：2012-04-01 00:00:00

abstract：:A long-term high-fat diet may result in a fatty liver. However, whether or not high-fat diets affect the hepatic circadian clock is controversial. The objective of this study is to investigate the effects of timed high-fat diet on the hepatic circadian clock and clock-controlled peroxisome proliferator-activated recep...

journal_title：Genes & nutrition

authors： Wang X,Xue J,Yang J,Xie M

更新日期：2013-09-01 00:00:00

abstract：:Observational studies with healthy persons demonstrated an inverse association of vitamin E with the risk of coronary heart disease or cancer, the outcome of large-scale clinical trials conducted to prove a benefit of vitamin E in the recurrence and/or progression of such disease, however, was disappointing. Vitamin E...

journal_title：Genes & nutrition

authors： Brigelius-Flohé R

更新日期：2007-12-01 00:00:00