当前位置： SCI文献检索 > Journal of Inflammation-London期刊下所有文献 > Relationship between vitamin D status and the inflammatory state in patients with chronic spontaneous urticaria.

Relationship between vitamin D status and the inflammatory state in patients with chronic spontaneous urticaria.

Abstract：

BACKGROUND:Chronic spontaneous urticaria (CSU) is an immune-inflammatory disease, characterized by acute phase response (APR) and immune activation. There has been increasing evidence showing that vitamin D deficiency/insufficiency is associated with increased incidence and/or severity of immune-inflammatory disorders. AIM:To assess relationship between vitamin D status and C-reactive protein (CRP), a nonspecific inflammatory marker of CSU activity. METHODS:Concentrations of CRP and 25-hydroxyvitamin D [25(OH)D], a biomarker of vitamin D status were measured in serum of CSU patients and compared with the healthy controls. RESULTS:Serum 25(OH)D concentration was significantly lower in CSU group as compared with the normal subjects. The prevalence of vitamin D deficiency (< 20 ng/ml) was significantly higher in patients with CSU than among normal population. There were no significant differences in prevalence of 25(OH)D insufficiency between the groups. Serum CRP concentrations were significantly higher in CSU patients as compared with the healthy subjects. There were no significant correlations between CRP and 25(OH)D concentrations in CSU patients. CONCLUSIONS:CSU is associated with lower serum 25(OH)D concentration and higher prevalence of its deficiency. The results failed to show any effect of vitamin D status on circulating CRP concentrations in CSU. A potential role of vitamin D in pathogenesis and/or additive therapy of CSU needs to be examined in other cohorts of CSU patients as well as in larger studies.

journal_name

J Inflamm (Lond)

journal_title

Journal of inflammation (London, England)

authors

Grzanka A,Machura E,Mazur B,Misiolek M,Jochem J,Kasperski J,Kasperska-Zajac A

doi

10.1186/1476-9255-11-2

subject

Has Abstract

pub_date

2014-02-03 00:00:00

pages

2

issue

1

issn

1476-9255

pii

1476-9255-11-2

journal_volume

11

pub_type

杂志文章

相关文献

Journal of Inflammation-London文献大全
  • Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70.

    abstract：BACKGROUND:Rheumatoid arthritis (RA) is a chronic autoimmune disease, which causes synovial damage. Persistence of lymphocyte infiltrates in the rheumatoid synovium has been attributed to abnormal apoptosis. While not comprehensively investigated, perturbations in peripheral blood lymphocyte (PBL) apoptosis may also be...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-8-30

    authors： Moodley D,Mody GM,Chuturgoon AA

    更新日期：2011-11-03 00:00:00

  • Heparan sulfate proteoglycan-dependent neutrophil chemotaxis toward PR-39 cathelicidin.

    abstract：:Cathelicidins are mammalian proteins containing a C-terminal cationic antimicrobial domain. Porcine PR-39 cathelicidin affects leukocyte biology. Mechanisms of action may involve alteration of heparan sulfate proteoglycan-dependent functions in inflammatory cells. It was tested whether PR-39 affects human neutrophil m...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-3-14

    authors： Djanani A,Mosheimer B,Kaneider NC,Ross CR,Ricevuti G,Patsch JR,Wiedermann CJ

    更新日期：2006-11-02 00:00:00

  • Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages.

    abstract：BACKGROUND:Osteoarthritis (OA) is described by an imbalance between anabolic and catabolic processes in the affected joint. This dysregulation of metabolism affects not only chondrocytes within cartilage tissue but also the cells of the synovial membrane across the border of the joint. An important factor in OA is the ...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-016-0139-y

    authors： Bauer C,Niculescu-Morzsa E,Jeyakumar V,Kern D,Späth SS,Nehrer S

    更新日期：2016-09-13 00:00:00

  • Elevated expression of the toll like receptors 2 and 4 in obese individuals: its significance for obesity-induced inflammation.

    abstract：UNLABELLED: BACKGROUND:Expression profile of the toll like receptors (TLRs) on PBMCs is central to the regulation of proinflammatory markers. An imbalance in the TLRs expression may lead to several types of inflammatory disorders. Furthermore, the dynamic regulation of inflammatory activity and associated impaired pro...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-9-48

    authors： Ahmad R,Al-Mass A,Atizado V,Al-Hubail A,Al-Ghimlas F,Al-Arouj M,Bennakhi A,Dermime S,Behbehani K

    更新日期：2012-11-28 00:00:00

  • Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps.

    abstract：BACKGROUND:Activation of NADPH oxidase is required for neutrophil extracellular trap (NET) formation. Protein kinase C (PKC) is an upstream mediator of NADPH oxidase activation and thus likely to have a role in NET formation. METHODS:Pharmacological inhibitors were used to block PKC activity in neutrophils harvested f...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-10-12

    authors： Gray RD,Lucas CD,MacKellar A,Li F,Hiersemenzel K,Haslett C,Davidson DJ,Rossi AG

    更新日期：2013-03-21 00:00:00

  • Corpus cavernosum smooth muscle cell dysfunction and phenotype transformation are related to erectile dysfunction in prostatitis rats with chronic prostatitis/chronic pelvic pain syndrome.

    abstract：Background:The relationship between chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and erectile dysfunction (ED) has been shown in many studies. However, the specific mechanism remains unclear. This study was to investigate the corpus cavernosum smooth muscle cell function and phenotype transformation in Ex...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-019-0233-z

    authors： Wang GC,Huang TR,Hu YY,Wang KY,Shi H,Yin L,Peng B

    更新日期：2020-01-06 00:00:00

  • Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass.

    abstract：BACKGROUND:The arterial in line application of the leukocyte inhibition module (LIM) in the cardiopulmonary bypass (CPB) limits overshooting leukocyte activity during cardiac surgery. We studied in a porcine model whether LIM may have beneficial effects on cardiac function after CPB. METHODS:German landrace pigs under...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-4-21

    authors： Abdel-Rahman U,Margraf S,Aybek T,Lögters T,Bitu-Moreno J,Francischetti I,Kranert T,Grünwald F,Windolf J,Moritz A,Scholz M

    更新日期：2007-10-10 00:00:00

  • Interleukin-10 attenuates impairment of the blood-brain barrier in a severe acute pancreatitis rat model.

    abstract：Background:Impairment of the blood-brain barrier (BBB) in severe acute pancreatitis (SAP) could result in life-threatening pancreatic encephalopathy. Interleukin-10 (IL-10) is a classical cytokine that is well-known for its strong immunoregulatory and anti-inflammatory abilities. However, whether and how IL-10 protects...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-018-0180-0

    authors： Lin R,Chen F,Wen S,Teng T,Pan Y,Huang H

    更新日期：2018-02-27 00:00:00

  • Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCepsilon and JAK2 in RAW macrophages.

    abstract：BACKGROUND:Nuclear factor kappa B (NF-kappaB) has been shown to play an important role in regulating the expression of many genes involved in cell survival, immunity and in the inflammatory processes. NF-kappaB activation upregulates inducible nitric oxide synthase leading to enhanced nitric oxide production during an ...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-4-23

    authors： Jones E,Adcock IM,Ahmed BY,Punchard NA

    更新日期：2007-11-24 00:00:00

  • Liraglutide exhibits anti-inflammatory activity through the activation of the PKA/CREB pathway.

    abstract：:Qihong Que and colleagues found that liraglutide exhibited anti-inflammatory activity through the activation of the PKA/CREB pathway in an OA rat model. We believe there was a flaw in this research. In their first experiment, the sacrifice time of the 10 rats in the control group has not been stated. And when the rats...

    journal_title：Journal of inflammation (London, England)

    pub_type： 社论

    doi：10.1186/s12950-019-0225-z

    authors： Wang L,Feng L,Zhang J

    更新日期：2019-10-11 00:00:00

  • Knockdown of miR-155 protects microglia against LPS-induced inflammatory injury via targeting RACK1: a novel research for intracranial infection.

    abstract：BACKGROUND:Intracranial infection, one of the complications of traumatic brain injury, is usually associated with inflammation. Several microRNAs (miRNAs), including miR-155, have been reported to be critical modulators in peripheral and central nervous system inflammation. In this study, we investigated the role of mi...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-017-0162-7

    authors： Yin H,Song S,Pan X

    更新日期：2017-08-09 00:00:00

  • Post heat shock tolerance: a neuroimmunological anti-inflammatory phenomenon.

    abstract：: We previously showed that the progression of burn-induced injury was inhibited by exposing the peripheral area of injured skin to sublethal hyperthermia following the burn. We called this phenomenon post-heat shock tolerance. Here we suggest a mechanism for this phenomenon. Exposure of the peripheral primary hyperalg...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-6-7

    authors： Shahabi S,Hassan ZM,Jazani NH

    更新日期：2009-03-27 00:00:00

  • Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD.

    abstract：BACKGROUND:Chronic obstructive pulmonary disease is associated with numerous vascular effects including endothelial dysfunction, arterial stiffness and atherogenesis. It is also known that a decline in lung function is associated with increased cardiovascular comorbidity in smokers. The mechanism of this cardiopulmonar...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-7-34

    authors： Arunachalam G,Sundar IK,Hwang JW,Yao H,Rahman I

    更新日期：2010-07-22 00:00:00

  • Proanthocyanidins, from Ribes nigrum leaves, reduce endothelial adhesion molecules ICAM-1 and VCAM-1.

    abstract：BACKGROUND:The effects of proanthocyanidins (PACs), isolated from blackcurrant (Ribes nigrum L.) leaves, on neutrophil accumulation during inflammatory processes were investigated in vivo and in vitro. METHODS:In vivo studies were performed using carrageenin-induced pleurisy in rats pre-treated with PACs. Exudate volu...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-2-9

    authors： Garbacki N,Kinet M,Nusgens B,Desmecht D,Damas J

    更新日期：2005-08-09 00:00:00

  • A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage.

    abstract：BACKGROUND:Cardiopulmonary bypass (CPB) is a commonly used technique in cardiac surgery. CPB is however associated with a strong induction of systemic inflammatory response syndrome (SIRS) which in conjunction with ischemia and reperfusion may lead to multiple organ failure. The aim of the study was to establish and ch...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-014-0026-3

    authors： Engels M,Bilgic E,Pinto A,Vasquez E,Wollschläger L,Steinbrenner H,Kellermann K,Akhyari P,Lichtenberg A,Boeken U

    更新日期：2014-08-12 00:00:00

  • Simvastatin protects bladder and renal functions following spinal cord injury in rats.

    abstract：BACKGROUND:Urinary bladder and renal dysfunction are secondary events associated with spinal cord injury (SCI) in humans. These secondary events not only compromise quality of life but also delay overall recovery from SCI pathophysiology. Furthermore, in experimental models the effects of SCI therapy on bladder and ren...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-7-17

    authors： Shunmugavel A,Khan M,Te Chou PC,Dhindsa RK,Martin MM,Copay AG,Subach BR,Schuler TC,Bilgen M,Orak JK,Singh I

    更新日期：2010-04-19 00:00:00

  • Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn's disease/infectious colitis and healthy controls.

    abstract：BACKGROUND:Inhibition of prolyl hydroxylases (PHDs) leads to the induction of a transcriptional program that, in the gut, promotes intestinal epithelial cell survival. PHD inhibitors have recently been suggested as a promising alternative treatment for inflammatory bowel disease (IBD). In this study, we explored the co...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-10-36

    authors： Van Welden S,Laukens D,Ferdinande L,De Vos M,Hindryckx P

    更新日期：2013-11-20 00:00:00

  • Expression and activation of toll-like receptor 3 and toll-like receptor 4 on human corneal epithelial and conjunctival fibroblasts.

    abstract：BACKGROUND:Toll-like receptors (TLRs) are recognized as important contributors to the initiation and modulation of the inflammatory response in the eye. This study investigated the precise expression patterns and functionality of TLRs in human corneal epithelial cells (HCE) and in conjunctival fibroblasts (HCF). METHO...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-11-3

    authors： Erdinest N,Aviel G,Moallem E,Anteby I,Yahalom C,Mechoulam H,Ovadia H,Solomon A

    更新日期：2014-02-04 00:00:00

  • Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models.

    abstract：BACKGROUND:Genetic studies have pointed out that CD226 variants, encoding DNAM-1, could be associated with susceptibility to rheumatoid arthritis. Therefore, we aimed to determine the influence of DNAM-1 on the development of arthritis using the collagen-induced arthritis (CIA) mouse model. METHODS:CIA was induced in ...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-015-0056-5

    authors： Elhai M,Chiocchia G,Marchiol C,Lager F,Renault G,Colonna M,Bernhardt G,Allanore Y,Avouac J

    更新日期：2015-02-08 00:00:00

  • Portrait of inflammatory response to ionizing radiation treatment.

    abstract：:Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an imbalance in cell fate decision. IR is able to regulate several genes and factors involved in cell-cycle progression, survival and/or cell death, DNA repair and inflammation modulating an intracellular radiation-dependent re...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-015-0058-3

    authors： Di Maggio FM,Minafra L,Forte GI,Cammarata FP,Lio D,Messa C,Gilardi MC,Bravatà V

    更新日期：2015-02-18 00:00:00

  • Role of toll-like receptors in human iris pigment epithelial cells and their response to pathogen-associated molecular patterns.

    abstract：BACKGROUND:Toll-like receptor (TLR) activation is hypothesized to contribute to inflammatory eye disease including uveitis, yet the distribution pattern of TLRs in human uveal tissues remains poorly described. The purpose of this study was to investigate the expression profile of TLRs in human iris pigment epithelial c...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-11-20

    authors： Mai K,Chui JJ,Di Girolamo N,McCluskey PJ,Wakefield D

    更新日期：2014-07-16 00:00:00

  • Extracorporeal immune therapy with immobilized agonistic anti-Fas antibodies leads to transient reduction of circulating neutrophil numbers and limits tissue damage after hemorrhagic shock/resuscitation in a porcine model.

    abstract：BACKGROUND:Hemorrhagic shock/resuscitation is associated with aberrant neutrophil activation and organ failure. This experimental porcine study was done to evaluate the effects of Fas-directed extracorporeal immune therapy with a leukocyte inhibition module (LIM) on hemodynamics, neutrophil tissue infiltration, and tis...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-7-18

    authors： Lögters TT,Altrichter J,Paunel-Görgülü A,Sager M,Witte I,Ott A,Sadek S,Baltes J,Bitu-Moreno J,Schek A,Müller W,Jeri T,Windolf J,Scholz M

    更新日期：2010-04-20 00:00:00

  • Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids.

    abstract：: Roots and stem-bark of Mahonia aquifolium (Oregon grape) (Berberidaceae) are effectively used in the treatment of skin inflammatory conditions.In the present study, the effect of Mahonia aquifolium crude extract and its two representative alkaloid fractions containing protoberberine and bisbenzylisoquinoline (BBIQ) a...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-4-15

    authors： Rackova L,Oblozinsky M,Kostalova D,Kettmann V,Bezakova L

    更新日期：2007-07-16 00:00:00

  • JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin.

    abstract：BACKGROUND:Bee venom therapy has been used to treat inflammatory diseases including rheumatoid arthritis in humans and in experimental animals. We previously found that bee venom and melittin (a major component of bee venom) have anti-inflammatory effect by reacting with the sulfhydryl group of p50 of nuclear factor-ka...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-5-7

    authors： Park HJ,Lee HJ,Choi MS,Son DJ,Song HS,Song MJ,Lee JM,Han SB,Kim Y,Hong JT

    更新日期：2008-05-29 00:00:00

  • Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation.

    abstract：BACKGROUND:PTPH1 is a protein tyrosine phosphatase expressed in T cells but its effect on immune response is still controversial. PTPH1 dephosphorylates TCRzeta in vitro, inhibiting the downstream inflammatory signaling pathway, however no immunological phenotype has been detected in primary T cells derived from PTPH1-...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-7-16

    authors： Patrignani C,Lafont DT,Muzio V,Gréco B,Hooft van Huijsduijnen R,Zaratin PF

    更新日期：2010-03-30 00:00:00

  • PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population.

    abstract：BACKGROUND:Obesity configures a pathophysiological profile that predisposes the development of metabolic and cardiovascular diseases, critically impacting public health. The chronic dysregulation of immuno-metabolic components triggered by pediatric obesity is a common but scarcely understood aspect of the disease. Per...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-020-00264-2

    authors： Vargas-Sánchez K,Vargas L,Urrutia Y,Beltrán I,Rossi AB,Lozano HY,Guarín J,Losada-Barragán M

    更新日期：2020-10-31 00:00:00

  • Detection of cytokine protein expression in mouse lung homogenates using suspension bead array.

    abstract：BACKGROUND:The objective for this present study was to determine whether or not suspension bead array is a feasible method to detect changes in cytokine protein expression in mouse lung tissue homogenates. Here, we report on suspension bead array as a feasible method for detection of lipopolysaccharide (LPS)-evoked cha...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-3-15

    authors： McDuffie E,Obert L,Chupka J,Sigler R

    更新日期：2006-11-29 00:00:00

  • Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.

    abstract：BACKGROUND:Milk-derived bioactive peptides retain many biological properties and have therapeutic effects in cardiovascular disorders such as atherosclerosis. Under inflammatory conditions the expression of endothelial cells adhesion molecules is induced, increasing monocyte adhesion to human vessel wall, a critical st...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/s12950-014-0044-1

    authors： Marcone S,Haughton K,Simpson PJ,Belton O,Fitzgerald DJ

    更新日期：2015-01-20 00:00:00

  • Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production.

    abstract：BACKGROUND:Intermittent fasting (IF) improves healthy lifespan in animals by a mechanism involving reduced oxidative damage and increased resistance to stress. However, no studies have evaluated the impact of controlled meal frequency on immune responses in human subjects. OBJECTIVE:A study was conducted to establish ...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-8-6

    authors： Dixit VD,Yang H,Sayeed KS,Stote KS,Rumpler WV,Baer DJ,Longo DL,Mattson MP,Taub DD

    更新日期：2011-03-07 00:00:00

  • Cancer, inflammation and the AT1 and AT2 receptors.

    abstract：:The critical role of inappropriate inflammation is becoming accepted in many diseases that affect man, including cardiovascular diseases, inflammatory and autoimmune disorders, neurodegenerative conditions, infection and cancer.This review proposes that cancer up-regulates the angiotensin II type 1 (AT1) receptor thro...

    journal_title：Journal of inflammation (London, England)

    pub_type： 杂志文章

    doi：10.1186/1476-9255-1-3

    authors： Smith GR,Missailidis S

    更新日期：2004-09-30 00:00:00