Abstract：
BACKGROUND:Plasmodium falciparum malaria, is a major health problem in forested tribal belt of central India. Rapid and accurate methods are needed for the diagnosis of P. falciparum. We performed a blinded evaluation of the recently introduced Determine trade mark malaria pf test (Abbott, Laboratories, Japan) compared with microscopy and splenomegaly in children in epidemic prone areas of district Mandla to assess the impact of intervention measures. METHODS:Children aged 2-10 yrs with and without fever were examined for spleen enlargement by medical specialist by establishing a mobile field clinic. From these children thick blood smears were prepared from finger prick and read by a technician. Simultaneously, rapid tests were performed by a field lab attendant. The figures for specificity, sensitivity and predictive values were calculated using microscopy as gold standard. RESULTS:In all 349 children were examined. The sensitivity and specificity for Determine rapid diagnostic test were 91 and 80% respectively. The positive predictive values (PPV), negative predictive values (NPV) and accuracy of the test were respectively 79, 91 and 85%. On the contrary, the sensitivity and specificity of spleen in detecting malaria infection were 57 and 74 % respectively with PPV of 73%, NPV 59 % and an accuracy of 65%. CONCLUSIONS:Determine trade mark malaria rapid diagnostic test is easier and quicker to perform and has other advantages over microscopy in not requiring prior training of personnel or quality control. Thus, highlighting the usefulness of a rapid antigen test in assessing prevailing malaria situation in remote areas.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Singh N,Shukla Mdoi
10.1186/1471-2334-1-10keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
10issn
1471-2334journal_volume
1pub_type
杂志文章abstract：BACKGROUND:The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limited settings. The new WHO guidelines 2016 continue to define virologic failure as two consecutive VL ≥1000 copies/mL (at...
journal_title：BMC infectious diseases
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1186/s12879-018-2979-y
更新日期：2018-02-12 00:00:00
abstract：:The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-exposure prophylaxis (PEP) for contacts of leprosy patients, reduces their risk to develop leprosy by 60%. This...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-018-3402-4
更新日期：2018-10-05 00:00:00
abstract：BACKGROUND:The usefulness of procalcitonin (PCT) measurement in critically ill medical patients with suspected nosocomial infection is unclear. The aim of the study was to assess PCT value for the early diagnosis of bacterial nosocomial infection in selected critically ill patients. METHODS:An observational cohort stu...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-9-49
更新日期：2009-04-22 00:00:00
abstract：BACKGROUND:Early antifungal therapy for invasive aspergillosis (IA) has been associated with improved outcome. Traditionally, of empiric antifungal therapy has been used for clinically suspected IA. We compared outcomes of patients with hematologic malignancy and IA who were treated with voriconazole using the diagnost...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-018-3584-9
更新日期：2018-12-13 00:00:00
abstract：BACKGROUND:Brucellosis is a zoonotic disease caused by brucella. It has been an increasing trend in recent years (Wang H, Xu WM, Zhu KJ, Zhu SJ, Zhang HF, Wang J, Yang Y, Shao FY, Jiang NM, Tao ZY, Jin HY, Tang Y, Huo LL, Dong F, Li ZJ, Ding H, Liu ZG, Emerg Microbes Infect 9:889-99, 2020). Brucellosis is capable to in...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-05358-z
更新日期：2020-09-07 00:00:00
abstract：BACKGROUND:Middle East Respiratory Syndrome (MERS) is caused by MERS coronavirus (MERS-CoV). More than 80% of reported cases have occurred in Saudi Arabia, with a mortality exceeding 50%. Health-care workers (HCWs) are at risk of acquiring and transmitting this virus, so the concerns of HCWs in Saudi Arabia regarding M...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-016-2096-8
更新日期：2017-01-03 00:00:00
abstract：BACKGROUND:NOD2, an intracellular pathogen recognition sensor, modulates innate defences to muropeptides derived from various bacterial species, including Mycobacterium tuberculosis (MTB). Experimentally, NOD2 attenuates two key putative mycobactericidal mechanisms. TNF-alpha synthesis is markedly reduced in MTB-antige...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-7-96
更新日期：2007-08-16 00:00:00
abstract：BACKGROUND:Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing and treatment programs have been advocated as a method for decreasing transmission at the population level. Little is known, however, about the extent to which sexually transmitted infections (STIs), which increase the HIV infectious...
journal_title：BMC infectious diseases
pub_type： 杂志文章,meta分析,评审
doi：10.1186/s12879-015-0961-5
更新日期：2015-06-30 00:00:00
abstract：BACKGROUND:The mobility of female sex workers (FSWs) is a factor in the geographic spread of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). This study describes FSW mobility patterns in a high risk area of China to identify factors associated with increased mobility, and to study t...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-10-198
更新日期：2010-07-09 00:00:00
abstract：BACKGROUND:Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. There are however few longitudinal studies on the changes in case fatality rate of IPD in recent years. We carried out a prospective observational study of patients with IPD in Nord Trøndelag county in Norwa...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-016-1553-8
更新日期：2016-05-23 00:00:00
abstract：BACKGROUND:Haemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by various types of viruses of the genus Hantavirus, which are mainly transmitted by contact with the infected rodents and their droppings. Pregnancy complicated with HFRS is rare; however, adverse maternal and foetal outcomes...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-05638-8
更新日期：2020-12-03 00:00:00
abstract：BACKGROUND:Arthropod-borne viral encephalitis of diverse origins shows similar clinical symptoms, histopathology and magnetic resonance imaging, indicating that the patho mechanisms may be similar. There is no specific therapy to date. However, vaccination remains the best prophylaxis against a selected few. Regardless...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-13-306
更新日期：2013-07-03 00:00:00
abstract：BACKGROUND:Poor outcomes of invasive candidiasis (IC) are associated with the difficulty in establishing the microbiological diagnosis at an early stage. New scores and laboratory tests have been developed in order to make an early therapeutic intervention in an attempt to reduce the high mortality associated with inva...
journal_title：BMC infectious diseases
pub_type： 杂志文章,多中心研究
doi：10.1186/1471-2334-11-60
更新日期：2011-03-09 00:00:00
abstract：BACKGROUND:Procalcitonin (PCT) is an inflammatory marker that has been used as indicator of severe bacterial infection. We evaluated the concentrations of PCT as a marker for systemic infection compared to C-reactive protein (CRP) in patients neutropenic febrile. METHODS:52 adult patients were enrolled in the study. B...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-7-137
更新日期：2007-11-22 00:00:00
abstract：BACKGROUND:Non-brucellar and non-tuberculous infectious sacroiliitis (ISI) is a rare disease, with misleading clinical signs that delay diagnosis. Most observations are based on isolated case reports or small case series. Our aim was to describe the clinical, bacteriological, and radiological characteristics of ISI, as...
journal_title：BMC infectious diseases
pub_type： 杂志文章,多中心研究
doi：10.1186/1471-2334-12-305
更新日期：2012-11-15 00:00:00
abstract：BACKGROUND:The ocular manifestations of HIV may lead to visual impairment or blindness. In India, patients typically initiate antiretroviral treatment (ART) with low CD4 cell counts when the risk of ocular complications may be high. The objective of this study was to determine the prevalence and types of HIV-associated...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-9-158
更新日期：2009-09-23 00:00:00
abstract：BACKGROUND:This report discusses a case of unsuccessful treatment with recombinant factor VIIa (rFVIIa) in off-label use. The need for international guidelines concerning the off-label use of rFVIIa is outlined as well as the need for methods to control the efficacy of rFVIIa objectively. CASE PRESENTATION:54 year old...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-7-34
更新日期：2007-04-26 00:00:00
abstract：BACKGROUND:Microascus cirrosus, the teleomorph of Scopulariopsis spp., is a saprobic species with a worldwide distribution and rarely causes human infection. In the present paper, we present the first case of primary cutaneous M. cirrosus infection in a Chinese female. CASE PRESENTATION:A 17-year-old female presented ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-018-3535-5
更新日期：2018-12-03 00:00:00
abstract：BACKGROUND:Regardless of chronic treatment with antiretroviral therapy (ART), the switching rate for ART regarding anchor drugs has not been articulated in real-world clinical-settings in Japan. We assessed switch rates and time-to-switch of ART regimens according to anchor drug classes (integrase strand transfer inhib...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4129-6
更新日期：2019-06-10 00:00:00
abstract：BACKGROUND:Cancer and sepsis comorbidity is a major public health problem in most parts of the world including Zimbabwe. The microbial aetiologies of sepsis and their antibiograms vary with time and locations. Knowledge on local microbial aetiologies of sepsis and their susceptibility patterns is critical in guiding em...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-4886-2
更新日期：2020-02-21 00:00:00
abstract：BACKGROUND:Australia is developing a chlamydia screening program. This study aimed to determine the attitudes of young women to the introduction of chlamydia screening in Australian General Practice. METHODS:In-depth face-to-face interviews with 24 young women from across Victoria, Australia, attending a randomly sele...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-8-62
更新日期：2008-05-09 00:00:00
abstract：BACKGROUND:Specific land cover types and activities have been correlated with Trypanosoma brucei rhodesiense distributions, indicating the importance of landscape for epidemiological risk. However, methods proposed to identify specific areas with elevated epidemiological risk (i.e. where transmission is more likely to ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-12-316
更新日期：2012-11-21 00:00:00
abstract：BACKGROUND:Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION:We report the first case of CHIKV infec...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-9-200
更新日期：2009-12-10 00:00:00
abstract：BACKGROUND:People successfully completing treatment for tuberculosis remain at elevated risk for recurrent disease, either from relapse or reinfection. Identifying risk factors for recurrent tuberculosis may help target post-tuberculosis screening and care. METHODS:We enrolled 500 patients with smear-positive pulmonar...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-05515-4
更新日期：2020-10-23 00:00:00
abstract：BACKGROUND:In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and the 69 kDa pertactin adhesin. One vaccine also contains pertussis ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-6-53
更新日期：2006-03-16 00:00:00
abstract：BACKGROUND:Tuberculosis (TB) contact tracing is a key strategy for containing TB and provides addition to the passive case finding approach. However, this practice has not been implemented in Tanzania, where there is unacceptably high treatment gap of 62.1% between cases estimated and cases detected. Therefore calls fo...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-018-3036-6
更新日期：2018-03-06 00:00:00
abstract：BACKGROUND:Central nervous system (CNS) infections are a significant contributor to morbidity and mortality globally. However, most published studies have been conducted in developed countries where the epidemiology and aetiology differ significantly from less developed areas. Additionally, there may be regional differ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-016-1640-x
更新日期：2016-06-16 00:00:00
abstract：BACKGROUND:International contact-tracing (CT) following exposure during long-distance air travel is resource-intensive, whereas evidence for risk of tuberculosis (TB) transmission during international travel is weak. In this study, we systematically analyzed the information from international requests for CT received a...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-04982-z
更新日期：2020-04-06 00:00:00
abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a major public health burden in China although it has steadily declined over the last two decades. A valid updated prevalence of HBV infection in China relies on a large sample size. Hence this study aimed to estimate HBV seroprevalence using a large inpatient population ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4091-3
更新日期：2019-05-20 00:00:00
abstract：BACKGROUND:The purposes of this study were to determine the incidence of central and peripheral venous catheter-related bacteraemias, the relationship between the suspected and final confirmed bacteraemia origins, and the differences in microbiological, epidemiological, clinical, and analytical characteristics between ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4505-2
更新日期：2019-10-15 00:00:00
