Using the Bernoulli trial approaches for detecting ordered alternatives.

abstract：BACKGROUND:Syntheses of qualitative studies can inform health policy, services and our understanding of patient experience. Meta-ethnography is a systematic seven-phase interpretive qualitative synthesis approach well-suited to producing new theories and conceptual models. However, there are concerns about the quality ...

journal_title：BMC medical research methodology

authors： France EF,Ring N,Thomas R,Noyes J,Maxwell M,Jepson R

更新日期：2014-11-19 00:00:00

abstract：BACKGROUND:In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clustered within primary ...

journal_title：BMC medical research methodology

authors： Stuart B,Becque T,Moore M,Little P

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Clinical quality registries and other systems that conduct routine post-discharge surveillance of patient outcomes following surgery may have difficulty surveying patients who have limited proficiency in the language of the healthcare provider. Interpreter proxies (family and carers) are often used due to li...

journal_title：BMC medical research methodology

authors： Xue D,Churches T,Armstrong E,Mittal R,Naylor JM,Harris IA

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics ...

journal_title：BMC medical research methodology

authors： de Hoop E,van der Tweel I,van der Graaf R,Moons KG,van Delden JJ,Reitsma JB,Koffijberg H

更新日期：2015-10-30 00:00:00

abstract：:Clinical Decision Support Systems (CDSS) provide aid in clinical decision making and therefore need to take into consideration human, data interactions, and cognitive functions of clinical decision makers. The objective of this paper is to introduce a high level reference model that is intended to be used as a foundat...

journal_title：BMC medical research methodology

authors： Zikos D,DeLellis N

更新日期：2018-11-16 00:00:00

abstract：BACKGROUND:There is a recognised need to build primary care medication adherence services which are tailored to patients' needs. Continuous quality improvement of such services requires a regular working method of measuring adherence in order to monitor effectiveness. Self report has been considered the method of choic...

journal_title：BMC medical research methodology

authors： Garfield S,Clifford S,Eliasson L,Barber N,Willson A

更新日期：2011-11-03 00:00:00

abstract：BACKGROUND:The primary aim of this study was to provide an estimate of effect size for the functional outcome of operative versus non-operative treatment for patients with an acute rupture of the Achilles tendon using accelerated rehabilitation for both groups of patients. The secondary aim was to assess the use of a c...

journal_title：BMC medical research methodology

authors： Kearney RS,Achten J,Parsons NR,Costa ML

更新日期：2011-04-05 00:00:00

abstract：BACKGROUND:Standard random-effects meta-analysis methods perform poorly when applied to few studies only. Such settings however are commonly encountered in practice. It is unclear, whether or to what extent small-sample-size behaviour can be improved by more sophisticated modeling. METHODS:We consider likelihood-based...

journal_title：BMC medical research methodology

authors： Seide SE,Röver C,Friede T

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Meta-analysis typically involves combining the estimates from independent studies in order to estimate a parameter of interest across a population of studies. However, outliers often occur even under the random effects model. The presence of such outliers could substantially alter the conclusions in a meta-a...

journal_title：BMC medical research methodology

authors： Gumedze FN,Jackson D

更新日期：2011-02-16 00:00:00

abstract：BACKGROUND:In order to accurately measure and monitor levels of moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) in older adults, cost efficient and valid instruments are required. To date, the International Physical Activity Questionnaire (IPAQ) has not been validated with older adults (aged ...

journal_title：BMC medical research methodology

authors： Cleland C,Ferguson S,Ellis G,Hunter RF

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:Self-administered questionnaires are becoming increasingly common in general practice. Much research has explored methods to increase response rates but comparatively few studies have explored the effect of questionnaire administration on reported answers. METHODS:The aim of this study was to determine the ...

journal_title：BMC medical research methodology

authors： Desborough JA,Butters P,Bhattacharya D,Holland RC,Wright DJ

更新日期：2008-06-27 00:00:00

abstract：BACKGROUND:Cluster randomised controlled trials (CRCTs) are frequently used in health service evaluation. Assuming an average cluster size, required sample sizes are readily computed for both binary and continuous outcomes, by estimating a design effect or inflation factor. However, where the number of clusters are fix...

journal_title：BMC medical research methodology

authors： Hemming K,Girling AJ,Sitch AJ,Marsh J,Lilford RJ

更新日期：2011-06-30 00:00:00

abstract：BACKGROUND:Mean arterial pressure (MAP), bispectral index (BIS), and minimum alveolar concentration (MAC) represent valuable, yet dynamic intraoperative monitoring variables. They provide information related to poor outcomes when considered together, however their collective behavior across time has not been characteri...

journal_title：BMC medical research methodology

authors： Schnetz MP,Hochheiser HS,Danks DJ,Landsittel DP,Vogt KM,Ibinson JW,Whitehurst SL,McDermott SP,Duque MG,Kaynar AM

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:The most commonly used survey methods are self-administered questionnaires, telephone interviews, and a mixture of both. But until now evidence out of randomised controlled trials as to whether patient responses differ depending on the survey mode is lacking. Therefore this study assessed whether patient res...

journal_title：BMC medical research methodology

authors： Lungenhausen M,Lange S,Maier C,Schaub C,Trampisch HJ,Endres HG

更新日期：2007-11-22 00:00:00

abstract：BACKGROUND:Data on lifetime exposures are often self-reported in epidemiologic studies, sometimes many years after the relevant age. Validity of self-reported data is usually inferred from their agreement with measured values, but few studies directly quantify the likely effects of reporting errors in body size and rep...

journal_title：BMC medical research methodology

authors： Cairns BJ,Liu B,Clennell S,Cooper R,Reeves GK,Beral V,Kuh D

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:The reporting of randomised controlled trial (RCT) abstracts is of vital importance. The primary objective of this study was to investigate the association between structure format and RCT abstracts' quality of methodology reporting, informed by the current requirement and usage of structure formats by leadi...

journal_title：BMC medical research methodology

authors： Hua F,Walsh T,Glenny AM,Worthington H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report. Administrative records only provide a partial representation of health care costs and have additional limitations. Patient-completed questio...

journal_title：BMC medical research methodology

authors： Pinto D,Robertson MC,Hansen P,Abbott JH

更新日期：2011-04-13 00:00:00

abstract：BACKGROUND:Aboriginal and Torres Strait Islander peoples are under-reported in administrative health datasets in NSW, Australia. Correct reporting of Aboriginal and Torres Strait Islander peoples is essential to measure the effectiveness of policies and programmes aimed at reducing the health disadvantage experienced b...

journal_title：BMC medical research methodology

authors： Taylor LK,Bentley J,Hunt J,Madden R,McKeown S,Brandt P,Baker D

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the pop...

journal_title：BMC medical research methodology

authors： Wahlgren L,Schantz P

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:To accurately predict the response to treatment, we need a stable and effective risk score that can be calculated from patient characteristics. When we evaluate such risks from time-to-event data with right-censoring, Cox's proportional hazards model is the most popular for estimating the linear risk score. ...

journal_title：BMC medical research methodology

authors： Omae K,Eguchi S

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:Identifying and assessing degree and type of frailty among older persons is a major challenge when targeting high risk populations to identify preventive interventions. The Vulnerable Elders Survey-(VES-13) is a simple instrument to identify frailty defined as risk for death, functional decline or institutio...

journal_title：BMC medical research methodology

authors： Belmin J,Khellaf L,Pariel S,Jarzebowski W,Valembois L,Zeisel J,Lafuente-Lafuente C

更新日期：2020-02-05 00:00:00

abstract：:The quality of a consultation provided by a physician can have a profound impact on the quality of care and patient engagement in treatment decisions. When the COPD Assessment Test (CAT) was developed, one of its aims was to aid the communication between physician and patient about the impact of COPD. We developed a n...

journal_title：BMC medical research methodology

authors： Gruffydd-Jones K,Marsden H,Holmes S,Kardos P,Escamilla R,Dal Negro R,Roberts J,Nadeau G,Leather D,Jones P

更新日期：2013-05-10 00:00:00

abstract：BACKGROUND:Occupational stress and specifically job anxiety are crucial factors in determining health outcomes, job satisfaction as well as performance. In order to assess this phenomenon, the Job Anxiety Scale is one of the instruments available. It consists of 70 items that are clustered in 14 subscales and five dime...

journal_title：BMC medical research methodology

authors： Schmalbach B,Kalkbrenner A,Bassler M,Hinz A,Petrowski K

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Methods for describing one's confidence in the available evidence are useful for end-users of evidence reviews. Analysts inevitably make judgments about the quality, quantity consistency, robustness, and magnitude of effects observed in the studies identified. The subjectivity of these judgments in several a...

journal_title：BMC medical research methodology

authors： Treadwell JR,Tregear SJ,Reston JT,Turkelson CM

更新日期：2006-10-19 00:00:00

abstract：BACKGROUND:There are detailed reviews about different recruitment strategies, but not with regard to differences between recruitment of hospital-based versus office-based physicians. Within this study, the two different recruitment schemes are compared. Advantages and disadvantages of different ways of recruitment in r...

journal_title：BMC medical research methodology

authors： Zeissig SR,Weyer-Elberich V,Emrich K,Binder H,Fischbeck S,Imruck BH,Friedrich-Mai P,Beutel ME,Blettner M

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:In many studies the information of patients who are dying in the hospital is censored when examining the change in length of hospital stay (cLOS) due to hospital-acquired infections (HIs). While appropriate estimators of cLOS are available in literature, the existence of the bias due to censoring of deaths w...

journal_title：BMC medical research methodology

authors： Rahman S,von Cube M,Schumacher M,Wolkewitz M

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Typically, randomization software should allow users to exert control over the different aspects of randomization including block design, provision of unique identifiers and control over the format and type of program output. While some of these characteristics have been addressed by available software, none...

journal_title：BMC medical research methodology

authors： Saghaei M

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:Recruitment to clinical trials can be challenging. Methods that improve the efficiency of trial recruitment are needed to increase successful study completions. The aim of this study was to ascertain whether sending an audio-visual presentation on a digital versatile disc (DVD), along with usual study invita...

journal_title：BMC medical research methodology

authors： Rogers A,Flynn RWV,Mackenzie IS,MacDonald TM

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:In prognostic studies model instability and missing data can be troubling factors. Proposed methods for handling these situations are bootstrapping (B) and Multiple imputation (MI). The authors examined the influence of these methods on model composition. METHODS:Models were constructed using a cohort of 58...

journal_title：BMC medical research methodology

authors： Vergouw D,Heymans MW,Peat GM,Kuijpers T,Croft PR,de Vet HC,van der Horst HE,van der Windt DA

更新日期：2010-09-17 00:00:00

abstract：BACKGROUND:E1684 was the pivotal adjuvant melanoma trial for establishment of high-dose interferon (IFN) as effective therapy of high-risk melanoma patients. E1690 was an intriguing effort to corroborate E1684, and the differences between the outcomes of these trials have embroiled the field in controversy over the pas...

journal_title：BMC medical research methodology

authors： Ibrahim JG,Chen MH,Chu H

更新日期：2012-11-29 00:00:00