Abundant daily non-sedentary activity is associated with reduced prevalence of metabolic syndrome and insulin resistance.

Abstract:

BACKGROUND:Non-exercise activity thermogenesis has recently drawn attention because of its potential to prevent weight gain. AIM:This study evaluated the relationships between the duration of daily non-sedentary activities and the prevalence of metabolic syndrome and insulin resistance (IR) in the Japanese population. MATERIAL/SUBJECTS AND METHODS:A total of 518 eligible subjects (380 men and 138 women) who attended the Tokushima Prefectural General Health Checkup Center and participated in the baseline survey of a cohort study conducted in Tokushima Prefecture, Japan were analyzed. Information about lifestyle characteristics including leisure-time exercise and daily non-exercise activities was obtained from a questionnaire. Logistic and multiple linear regression analyses were performed to evaluate the associations between the duration of daily non-exercise non-sedentary activities (beyond sitting) and prevalence of metabolic syndrome (and its components) and IR. RESULTS:Subjects with longer duration of daily non-sedentary activities had significantly lower adjusted odds ratios for metabolic syndrome (p for trend =0.024), abdominal obesity (p for trend =0.023), and low HDLcholesterol levels (p for trend =0.002), after adjustment for sex, age, and other probable covariates including leisure-time exercise. Longer duration of daily non-sedentary activities was further associated with lower homeostasis model of assessment- IR (HOMA-IR) values (p for trend =0.009). CONCLUSIONS:Our results suggest that abundant daily non-sedentary activity might be associated with a lower prevalence of metabolic syndrome, especially for the components of central obesity and low HDL-cholesterol levels, and with a lower prevalence of IR, independent of leisure-time exercise.

journal_name

J Endocrinol Invest

authors

Uemura H,Katsuura-Kamano S,Yamaguchi M,Nakamoto M,Hiyoshi M,Arisawa K

doi

10.3275/9066

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

1069-75

issue

11

eissn

0391-4097

issn

1720-8386

pii

9066

journal_volume

36

pub_type

杂志文章
  • Estrogen and progesterone receptors in the human vagina.

    abstract::Estrogen (E) and progesterone (Pg) receptor (R) levels were determined in the human vagina in relation to menopausal status, day of ovarian cycle and pregnancy. The results obtained confirmed that the human vagina contains ER and, in addition, demonstrated for the first time the presence of PgR in this organ in humans...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350667

    authors: Di Carlo F,Racca S,Gallo E,Conti G,Russo A,Mondo F,Francalanci S

    更新日期:1985-04-01 00:00:00

  • Identification of genes in thyrocytes regulated by unfolded protein response by using disulfide bond reducing agent of dithiothreitol.

    abstract::Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345141

    authors: Park S,Hwang I,Shong M,Kwon OY

    更新日期:2003-02-01 00:00:00

  • New achievement and novel therapeutic applications of PDE5 inhibithors in older males.

    abstract::Erectile dysfunction (ED) increases in prevalence and severity because of aging processes and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is observed with age and also in illnesses with a common basis of endothelial damage. The T deficiency may lead to decreased energy, mood dep...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Frajese GV,Pozzi F

    更新日期:2005-01-01 00:00:00

  • Thyroid hormone inhibition of intermediary metabolism in dog thyroid slices stimulated by different agonists.

    abstract::The role of thyroid hormones in a short loop feedback in the thyroid is controversial. This process was studied in dog thyroid slices stimulated by TSH, carbachol and phorbol esters. Incubation of thyroid slices with T3 and T4 for 1 hour inhibited the subsequent stimulation of glucose oxidation induced by carbachol an...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347936

    authors: Pasquali D,Bellastella A,Field JB

    更新日期:1991-11-01 00:00:00

  • From inflammation to sexual dysfunctions: a journey through diabetes, obesity, and metabolic syndrome.

    abstract::Metabolic diseases are associated with chronic low-grade inflammation, which has been indicated as a potential mediator of endothelial dysfunction and cardiovascular disease. Visceral adiposity is thought to be the starting condition of the inflammatory state through the release of inflammatory cytokines, including TN...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/s40618-018-0872-6

    authors: Maiorino MI,Bellastella G,Giugliano D,Esposito K

    更新日期:2018-11-01 00:00:00

  • Rhythm characteristics of plasma renin, aldosterone and cortisol in five subtypes of mesor-hypertension.

    abstract::The possible role of the renin-angiotensin system and ACTH in controlling the temporal organization of circadian rhythm of aldosterone was studied in patients with mesor-hypertension (MH) by simultaneous radioimmunological determinations of within-day changes in plasma renin, aldosterone and cortisol. Thirty-nine unco...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348241

    authors: Cugini P,Manconi R,Serdoz R,Mancini A,Meucci T,Scavo D

    更新日期:1980-04-01 00:00:00

  • Radioiodine therapy of metastatic lesions of differentiated thyroid cancer.

    abstract::Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TS...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Luster M,Hänscheid H,Freudenberg LS,Verburg FA

    更新日期:2012-01-01 00:00:00

  • Adrenopause: an imbalance between dehydroepiandrosterone (DHEA) and cortisol secretion.

    abstract::Several clinical signs might be related to the decline of DHEA secretion in aged people: sarcopenia, osteopenia, atherosclerosis progression, impairment of cognitive and affective performances, deterioration of immunocompetence are the most significant evidences. In addition, in aged people this clinical condition mig...

    journal_title:Journal of endocrinological investigation

    pub_type:

    doi:

    authors: Valenti G

    更新日期:2002-01-01 00:00:00

  • Reference ranges for an automated chemiluminescent assay for serum insulin-like growth factor I (IGF-I) in a large population of healthy adults from Buenos Aires.

    abstract:PURPOSE:Insulin-like growth factor I (IGF-I) represents an essential tool in the diagnostic work-up and in the monitoring of treatment efficacy for somatotrophic axis disorders both in children and adults. A large number of factors including, but not limited to, age, sex and weight as well as analytical variables influ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-015-0265-z

    authors: Guitelman M,Smithuis F,Garcia Basavilbaso N,Aranda C,Fabre B,Oneto A

    更新日期:2015-09-01 00:00:00

  • A comparison of the direct immunobead test and other tests for sperm antibodies detection.

    abstract::The authors report the results of a correlation study between the direct Immunobead Test (d-IBT) and other techniques for antisperm antibodies detection. The Gelatin Agglutination Test (GAT) and Tray Agglutination Test (TAT) were used to detect antibodies in blood serum and seminal plasma ("indirect methods"). The Dir...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346835

    authors: Dondero F,Lenzi A,Gandini L,Lombardo F,Culasso F

    更新日期:1991-06-01 00:00:00

  • Serum leptin levels in males with delayed puberty during short-term pulsatile GnRH administration.

    abstract::Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345471

    authors: Giusti M,Guido R,Valenti S,Giordano G

    更新日期:1999-01-01 00:00:00

  • Expression and ligand binding of bombesin receptors in pulmonary and intestinal carcinoids.

    abstract:INTRODUCTION:Carcinoids are mainly found in the gastrointestinal (65%) and bronchopulmonary tract (25%). These neuroendocrine tumors secrete a wide range of bioactive peptides, including gastrin releasing peptide and neuromedin B, the mammalian analogs of bombesin. The purpose of this study was to investigate the quant...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7332

    authors: Kuiper P,Verspaget HW,Biemond I,de Jonge-Muller ES,van Eeden S,van Velthuysen ML,Taal BG,Lamers CB

    更新日期:2011-10-01 00:00:00

  • Lack of ACTH lowering effect of sodium valproate in patients with ACTH hypersecretion.

    abstract::The effect of an oral dose of 200 or 400 mg sodium valproate (DPA) on ACTH and cortisol secretion was assessed in 11 patients with Cushing's disease (3 bilaterally adrenalectomized), 3 patients with Nelson's syndrome and 6 patients with Addison's disease. In none of the patients examined DPA induced changes in ACTH (a...

    journal_title:Journal of endocrinological investigation

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF03348396

    authors: Loli P,Berselli ME,Frascatani F,Muratori F,Tagliaferri M

    更新日期:1984-04-01 00:00:00

  • Vitamin D levels in a paediatric population of normal weight and obese subjects.

    abstract:BACKGROUND:Vitamin D exerts pleiotropic effects and few studies are available in the Italian population. AIM:Aim of our study was to evaluate vitamin D status in children living in Northern Italy. METHODS:We studied vitamin D levels in a population of 113 normal weight (NW) and 444 obese (OB) children, prepubertal an...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-014-0108-3

    authors: Bellone S,Esposito S,Giglione E,Genoni G,Fiorito C,Petri A,Bona G,Prodam F

    更新日期:2014-09-01 00:00:00

  • Human insulin-specific immunoglobulin G antibody and hypoglycemic attacks after the injection of gold thioglucose.

    abstract::A 56-year-old woman with granulomas of gold thioglucose in her hips exhibited recurrent bouts of hypoglycemic attacks. The first attack occurred 2 years after the last injection of gold thioglucose, when large amounts of extractable insulin and human insulin-specific antibody were noted in her serum. Histological exam...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348654

    authors: Yao K,Uchigata Y,Kyono H,Yokoyama H,Eguchi Y,Fukushima H,Yamauchi K,Hirata Y

    更新日期:1992-01-01 00:00:00

  • Arterial erectile dysfunction: reliability of new markers of endothelial dysfunction.

    abstract:OBJECTIVE:Blood endothelial progenitor cells (EPC) and microparticles (EMP) have been proposed as markers of endothelial dysfunction. Aim of this study was to evaluate a new immunophenotype of EPC and EMP in patients with arterial erectile dysfunction (AED) compared to psychogenic erectile dysfunction (PED). MATERIALS...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346728

    authors: La Vignera S,Condorelli R,Vicari E,D'Agata R,Calogero AE

    更新日期:2011-11-01 00:00:00

  • An uncommon large deletion in the androgen-receptor gene in a XY female with complete androgen insensitivity syndrome.

    abstract::Androgen insensitivity is a disorder characterized by an abnormal male sexual development, in which the androgen action is impaired due to structural defects in the androgen receptor gene. We report a case of a 46,XY subject with female phenotype (normal breast and external genitalia) lacking sexual hair, affected wit...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03344130

    authors: Moretti C,Odorisio T,Geremia R,Grimaldi P

    更新日期:2006-05-01 00:00:00

  • Comparison of single and combined tests for the evaluation of plasma growth hormone secretion in normal short children.

    abstract::Growth hormone (GH) response to provocative tests was compared in normal short children. Seven of 23 children failed to respond to insulin hypoglycemia. Using insulin hypoglycemia followed by L-dopa only 2 of 23 children did not respond and giving bromocriptine combined with insulin hypoglycemia only 1 of 8 children f...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03351005

    authors: Bazán MC,Domené H,Heinrich JJ,Barontini M,Bergadá C

    更新日期:1984-08-01 00:00:00

  • Hyperprolactinemia affects spermiogenesis in adult male rats.

    abstract::The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345528

    authors: Aleem M,Choudhari J,Padwal V,Balasinor N,Parte P,Gill-Sharma MK

    更新日期:2005-01-01 00:00:00

  • Potential treatment of hypoparathyroidism with recombinant plasmids encoding preproparathyroid hormone.

    abstract::Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, we established a recombinant plasmid encoding a mutant preproPTH with a skeletal muscle creatine kinase promot...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7966

    authors: Liu D,Zhu Y,Yang C,Long J,Yao C,Li J,Wang S

    更新日期:2012-05-01 00:00:00

  • Differences in the cluster of depressive symptoms between subjects with type 2 diabetes and individuals with a major depressive disorder and without diabetes.

    abstract:BACKGROUND:Depressive disorder encompasses a wide spectrum of somatic and psychological symptoms. It is not known whether there are differences regarding the cluster of depressive symptomatology between subjects with depression with and without T2DM. PURPOSE:To explore whether the cluster of depression that prevails a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-019-01020-x

    authors: Nicolau J,Simó R,Conchillo C,Sanchís P,Blanco J,Romerosa JM,Fortuny R,Bonet A,Masmiquel L

    更新日期:2019-08-01 00:00:00

  • Long term thyroid function after subtotal thyroidectomy for Graves' disease.

    abstract::Between 1973 and 1980, 93 patients with Graves' disease underwent subtotal thyroidectomy by the same surgeon (the size of thyroid remnant was 4 g per side). No case of operative mortality, no case of thyroid storm nor of surgical complications occurred. Three months after surgery 40% of patients were euthyroid, 25% ha...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349057

    authors: Busnardo B,Girelli ME,Rubello D,Eccher C,Betterle C

    更新日期:1988-05-01 00:00:00

  • Testosterone therapy in men: clinical and pharmacological perspectives.

    abstract::There is increasing evidence that androgen therapy in men may be effectively applied in several conditions to improve well being and health. Classical indications for androgen therapy in males are represented by primary or secondary hypogonadism, delayed puberty, aplastic anemia and that secondary to chronic renal fai...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03343707

    authors: Gambineri A,Pasquali R

    更新日期:2000-03-01 00:00:00

  • Multiple intracranial recurrent tumors with hyperprolactinemia combined with a parasellar malignant fibrous histiocytoma long after transfrontal surgery and irradiation to a pituitary adenoma.

    abstract::We herein describe a 40-year-old woman with hyperprolactinemia, an empty sella and two extrasellar intracranial recurrent tumors which were revealed 23 years after the first transfrontal craniotomy and 18 years after the second transfrontal surgery and irradiation to a provable prolactin-producing pituitary macroadeno...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03351046

    authors: Fujikawa M,Okamura K,Sato K,Shiratsuchi M,Yao T,Mizokami T,Fujishima M

    更新日期:2001-06-01 00:00:00

  • Pluripotent stem cells isolated from human amniotic fluid and differentiation into pancreatic beta-cells.

    abstract::Human amniotic fluid (HAF) contains multipotent stem cells [amniotic fluid-derived stem cells (AFSC)] which can differentiate into a variety of different cell types. Recently, we demonstrated that obestatin, a peptide encoded by the ghrelin gene, exerts anti-apoptotic effects in pancreatic beta-cells and human islets ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345764

    authors: Trovato L,De Fazio R,Annunziata M,Sdei S,Favaro E,Ponti R,Marozio L,Ghigo E,Benedetto C,Granata R

    更新日期:2009-12-01 00:00:00

  • Cell adhesion molecule L1 like plays a role in the pathogenesis of idiopathic hypogonadotropic hypogonadism.

    abstract:PURPOSE:The pathogenesis of idiopathic hypogonadotropic hypogonadism (IHH) is genetically complex. The aims of this study were to investigate the genetic profile and clinical manifestation of IHH in a Chinese pedigree and to discover new IHH-associated genes. METHODS:The first step was to follow up the clinical phenot...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-020-01485-1

    authors: Chen Y,Sun T,Niu Y,Wang D,Liu K,Wang T,Wang S,Xu H,Liu J

    更新日期:2021-01-16 00:00:00

  • Effect of neonatal hypothyroidism on carbohydrate metabolism, insulin secretion, and pancreatic islets morphology of adult male offspring in rats.

    abstract:BACKGROUND:Neonatal hypothyroidism has serious effects on growth, development, and metabolism. AIM:This study aims to investigate the effects of the neonatal hypothyroidism on carbohydrate metabolism, islet insulin secretion and morphology of the pancreatic islets in adult male offspring. MATERIALS/SUBJECTS AND METHO...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/8468

    authors: Farahani H,Ghasemi A,Roghani M,Zahediasl S

    更新日期:2013-01-01 00:00:00

  • Premature pubarche, ovarian hyperandrogenism, hyperinsulinism and the polycystic ovary syndrome: from a complex constellation to a simple sequence of prenatal onset.

    abstract::Adolescent girls with a history of premature pubarche have an increased incidence of functional ovarian hyperandrogenism [a form of polycystic ovary syndrome (PCOS)] at adolescence, which is usually associated with hyperinsulinemia and dyslipemia. The hyperinsulinemia and lipid disturbances can often be detected in th...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03350781

    authors: Ibáñez L,de Zegher F,Potau N

    更新日期:1998-10-01 00:00:00

  • Absence of p53 mutation in Japanese patients with malignant thyroid lymphoma.

    abstract::Abnormalities of the gene encoding the sequence-specific DNA-binding protein, nuclear phosphorprotein p53, are among the most common genetic alterations observed in human cancers. A mutation of this tumor suppressor gene has been reported with a low prevalence in differentiated thyroid carcinomas, while the prevalence...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347774

    authors: Iyota K,Takeda K,Matsuzuka F,Okabayashi T,Morita S,Kuma K,Hashimoto K

    更新日期:1994-11-01 00:00:00

  • A virilizing Leydig cell tumor of the ovary associated with stromal hyperplasia under gonadotropin control.

    abstract::A 34-yr-old nulliparous black woman presented with hair loss, facial hirsutism, irregular menses and infertility associated with greatly increased serum total testosterone levels. The adrenal glands and the ovaries were normal on radiological and ultrasonographic investigation. Catheterization of the veins draining fr...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348033

    authors: Marcondes JA,Nery M,Mendonça BB,Hayashida SA,Halbe HW,Carvalho FM,Wajchenberg BL

    更新日期:1997-12-01 00:00:00