Abstract:
BACKGROUND:Non-exercise activity thermogenesis has recently drawn attention because of its potential to prevent weight gain. AIM:This study evaluated the relationships between the duration of daily non-sedentary activities and the prevalence of metabolic syndrome and insulin resistance (IR) in the Japanese population. MATERIAL/SUBJECTS AND METHODS:A total of 518 eligible subjects (380 men and 138 women) who attended the Tokushima Prefectural General Health Checkup Center and participated in the baseline survey of a cohort study conducted in Tokushima Prefecture, Japan were analyzed. Information about lifestyle characteristics including leisure-time exercise and daily non-exercise activities was obtained from a questionnaire. Logistic and multiple linear regression analyses were performed to evaluate the associations between the duration of daily non-exercise non-sedentary activities (beyond sitting) and prevalence of metabolic syndrome (and its components) and IR. RESULTS:Subjects with longer duration of daily non-sedentary activities had significantly lower adjusted odds ratios for metabolic syndrome (p for trend =0.024), abdominal obesity (p for trend =0.023), and low HDLcholesterol levels (p for trend =0.002), after adjustment for sex, age, and other probable covariates including leisure-time exercise. Longer duration of daily non-sedentary activities was further associated with lower homeostasis model of assessment- IR (HOMA-IR) values (p for trend =0.009). CONCLUSIONS:Our results suggest that abundant daily non-sedentary activity might be associated with a lower prevalence of metabolic syndrome, especially for the components of central obesity and low HDL-cholesterol levels, and with a lower prevalence of IR, independent of leisure-time exercise.
journal_name
J Endocrinol Investjournal_title
Journal of endocrinological investigationauthors
Uemura H,Katsuura-Kamano S,Yamaguchi M,Nakamoto M,Hiyoshi M,Arisawa Kdoi
10.3275/9066subject
Has Abstractpub_date
2013-12-01 00:00:00pages
1069-75issue
11eissn
0391-4097issn
1720-8386pii
9066journal_volume
36pub_type
杂志文章abstract::Estrogen (E) and progesterone (Pg) receptor (R) levels were determined in the human vagina in relation to menopausal status, day of ovarian cycle and pregnancy. The results obtained confirmed that the human vagina contains ER and, in addition, demonstrated for the first time the presence of PgR in this organ in humans...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03350667
更新日期:1985-04-01 00:00:00
abstract::Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...
journal_title:Journal of endocrinological investigation
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doi:10.1007/BF03345141
更新日期:2003-02-01 00:00:00
abstract::Erectile dysfunction (ED) increases in prevalence and severity because of aging processes and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is observed with age and also in illnesses with a common basis of endothelial damage. The T deficiency may lead to decreased energy, mood dep...
journal_title:Journal of endocrinological investigation
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abstract::The role of thyroid hormones in a short loop feedback in the thyroid is controversial. This process was studied in dog thyroid slices stimulated by TSH, carbachol and phorbol esters. Incubation of thyroid slices with T3 and T4 for 1 hour inhibited the subsequent stimulation of glucose oxidation induced by carbachol an...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03347936
更新日期:1991-11-01 00:00:00
abstract::Metabolic diseases are associated with chronic low-grade inflammation, which has been indicated as a potential mediator of endothelial dysfunction and cardiovascular disease. Visceral adiposity is thought to be the starting condition of the inflammatory state through the release of inflammatory cytokines, including TN...
journal_title:Journal of endocrinological investigation
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doi:10.1007/s40618-018-0872-6
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abstract::The possible role of the renin-angiotensin system and ACTH in controlling the temporal organization of circadian rhythm of aldosterone was studied in patients with mesor-hypertension (MH) by simultaneous radioimmunological determinations of within-day changes in plasma renin, aldosterone and cortisol. Thirty-nine unco...
journal_title:Journal of endocrinological investigation
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doi:10.1007/BF03348241
更新日期:1980-04-01 00:00:00
abstract::Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TS...
journal_title:Journal of endocrinological investigation
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doi:
更新日期:2012-01-01 00:00:00
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journal_title:Journal of endocrinological investigation
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doi:
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Insulin-like growth factor I (IGF-I) represents an essential tool in the diagnostic work-up and in the monitoring of treatment efficacy for somatotrophic axis disorders both in children and adults. A large number of factors including, but not limited to, age, sex and weight as well as analytical variables influ...
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doi:10.1007/s40618-015-0265-z
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03346835
更新日期:1991-06-01 00:00:00
abstract::Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03345471
更新日期:1999-01-01 00:00:00
abstract:INTRODUCTION:Carcinoids are mainly found in the gastrointestinal (65%) and bronchopulmonary tract (25%). These neuroendocrine tumors secrete a wide range of bioactive peptides, including gastrin releasing peptide and neuromedin B, the mammalian analogs of bombesin. The purpose of this study was to investigate the quant...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.3275/7332
更新日期:2011-10-01 00:00:00
abstract::The effect of an oral dose of 200 or 400 mg sodium valproate (DPA) on ACTH and cortisol secretion was assessed in 11 patients with Cushing's disease (3 bilaterally adrenalectomized), 3 patients with Nelson's syndrome and 6 patients with Addison's disease. In none of the patients examined DPA induced changes in ACTH (a...
journal_title:Journal of endocrinological investigation
pub_type: 临床试验,杂志文章
doi:10.1007/BF03348396
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:Vitamin D exerts pleiotropic effects and few studies are available in the Italian population. AIM:Aim of our study was to evaluate vitamin D status in children living in Northern Italy. METHODS:We studied vitamin D levels in a population of 113 normal weight (NW) and 444 obese (OB) children, prepubertal an...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-014-0108-3
更新日期:2014-09-01 00:00:00
abstract::A 56-year-old woman with granulomas of gold thioglucose in her hips exhibited recurrent bouts of hypoglycemic attacks. The first attack occurred 2 years after the last injection of gold thioglucose, when large amounts of extractable insulin and human insulin-specific antibody were noted in her serum. Histological exam...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03348654
更新日期:1992-01-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03346728
更新日期:2011-11-01 00:00:00
abstract::Androgen insensitivity is a disorder characterized by an abnormal male sexual development, in which the androgen action is impaired due to structural defects in the androgen receptor gene. We report a case of a 46,XY subject with female phenotype (normal breast and external genitalia) lacking sexual hair, affected wit...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03344130
更新日期:2006-05-01 00:00:00
abstract::Growth hormone (GH) response to provocative tests was compared in normal short children. Seven of 23 children failed to respond to insulin hypoglycemia. Using insulin hypoglycemia followed by L-dopa only 2 of 23 children did not respond and giving bromocriptine combined with insulin hypoglycemia only 1 of 8 children f...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03351005
更新日期:1984-08-01 00:00:00
abstract::The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03345528
更新日期:2005-01-01 00:00:00
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journal_title:Journal of endocrinological investigation
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pub_type: 杂志文章
doi:10.1007/s40618-019-01020-x
更新日期:2019-08-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03349057
更新日期:1988-05-01 00:00:00
abstract::There is increasing evidence that androgen therapy in men may be effectively applied in several conditions to improve well being and health. Classical indications for androgen therapy in males are represented by primary or secondary hypogonadism, delayed puberty, aplastic anemia and that secondary to chronic renal fai...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,评审
doi:10.1007/BF03343707
更新日期:2000-03-01 00:00:00
abstract::We herein describe a 40-year-old woman with hyperprolactinemia, an empty sella and two extrasellar intracranial recurrent tumors which were revealed 23 years after the first transfrontal craniotomy and 18 years after the second transfrontal surgery and irradiation to a provable prolactin-producing pituitary macroadeno...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03351046
更新日期:2001-06-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03345764
更新日期:2009-12-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-020-01485-1
更新日期:2021-01-16 00:00:00
abstract:BACKGROUND:Neonatal hypothyroidism has serious effects on growth, development, and metabolism. AIM:This study aims to investigate the effects of the neonatal hypothyroidism on carbohydrate metabolism, islet insulin secretion and morphology of the pancreatic islets in adult male offspring. MATERIALS/SUBJECTS AND METHO...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Journal of endocrinological investigation
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更新日期:1998-10-01 00:00:00
abstract::Abnormalities of the gene encoding the sequence-specific DNA-binding protein, nuclear phosphorprotein p53, are among the most common genetic alterations observed in human cancers. A mutation of this tumor suppressor gene has been reported with a low prevalence in differentiated thyroid carcinomas, while the prevalence...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03347774
更新日期:1994-11-01 00:00:00
abstract::A 34-yr-old nulliparous black woman presented with hair loss, facial hirsutism, irregular menses and infertility associated with greatly increased serum total testosterone levels. The adrenal glands and the ovaries were normal on radiological and ultrasonographic investigation. Catheterization of the veins draining fr...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03348033
更新日期:1997-12-01 00:00:00