Purpura and dermal thinning associated with high dose inhaled corticosteroids.

abstract：OBJECTIVE:To study the comparative importance of environment and genes in the development of islet cell autoimmunity associated with insulin dependent diabetes mellitus. DESIGN:Population based study of diabetic twins. SETTING:Danish population. SUBJECTS:18 monozygotic and 36 dizygotic twin pairs with one or both pa...

journal_title：BMJ (Clinical research ed.)

authors： Petersen JS,Kyvik KO,Bingley PJ,Gale EA,Green A,Dyrberg T,Beck-Nielsen H

更新日期：1997-05-31 00:00:00

abstract：OBJECTIVE:To investigate the effect of vitamin A supplementation and BCG vaccination at birth in low birthweight neonates. DESIGN:Randomised, placebo controlled, two by two factorial trial. SETTING:Bissau, Guinea-Bissau. PARTICIPANTS:1717 low birthweight neonates born at the national hospital. INTERVENTION:Neonates...

journal_title：BMJ (Clinical research ed.)

authors： Benn CS,Fisker AB,Napirna BM,Roth A,Diness BR,Lausch KR,Ravn H,Yazdanbakhsh M,Rodrigues A,Whittle H,Aaby P

更新日期：2010-03-09 00:00:00

abstract：OBJECTIVES:To clarify the type of fetal growth impairment associated with increased blood pressure in adult life, and to establish whether this association is influenced by obesity and is mediated through impairment of insulin action. DESIGN:Cross sectional survey with retrospective ascertainment of size at birth from...

journal_title：BMJ (Clinical research ed.)

authors： Leon DA,Koupilova I,Lithell HO,Berglund L,Mohsen R,Vagero D,Lithell UB,McKeigue PM

更新日期：1996-02-17 00:00:00

abstract：OBJECTIVE:To assess the effect of the timing of first postnatal home visit by community health workers on neonatal mortality. DESIGN:Analysis of prospectively collected data using time varying discrete hazard models to estimate hazard ratios for neonatal mortality according to day of first postnatal home visit. DATA ...

journal_title：BMJ (Clinical research ed.)

authors： Baqui AH,Ahmed S,El Arifeen S,Darmstadt GL,Rosecrans AM,Mannan I,Rahman SM,Begum N,Mahmud AB,Seraji HR,Williams EK,Winch PJ,Santosham M,Black RE,Projahnmo 1 Study Group.

更新日期：2009-08-14 00:00:00

abstract：OBJECTIVES:To compare the course and outcome of psychotic illness in a group of Afro-Caribbean patients resident in the United Kingdom and a group of white British patients. DESIGN:Cohort study of consecutive admissions followed up for four years. SUBJECTS:113 patients with psychotic illness of recent onset admitted ...

journal_title：BMJ (Clinical research ed.)

authors： McKenzie K,van Os J,Fahy T,Jones P,Harvey I,Toone B,Murray R

更新日期：1995-11-18 00:00:00

abstract：OBJECTIVE:To study different nutrients and food additives as risk factors for insulin dependent diabetes mellitus in childhood. DESIGN:Prospective case-control study. Parents of the children being studied were asked to fill in a questionnaire regarding the children's frequency of consumption of various foods. Parents ...

journal_title：BMJ (Clinical research ed.)

authors： Dahlquist GG,Blom LG,Persson LA,Sandström AI,Wall SG

更新日期：1990-05-19 00:00:00

abstract：OBJECTIVE:To assess oesophageal Doppler ultrasonography as a convenient means of optimising positive end expiratory pressure for maximal delivery of oxygen to tissues. DESIGN:Measurements of blood flow, arterial oxygen saturation, and cardiac output by thermodilution (when available) at baseline and at 20-30 minutes a...

journal_title：BMJ (Clinical research ed.)

authors： Singer M,Bennett D

更新日期：1989-05-20 00:00:00

abstract：OBJECTIVE:To estimate the effectiveness of delivering an anthelmintic through a community child health programme on the weight gain of preschool children in Uganda. DESIGN:Cluster randomised controlled trial. SETTING:Eastern Uganda. PARTICIPANTS:48 parishes participating in a new programme for child health: 24 offer...

journal_title：BMJ (Clinical research ed.)

authors： Alderman H,Konde-Lule J,Sebuliba I,Bundy D,Hall A

更新日期：2006-07-15 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness and costs of a multifaceted flexible educational programme aimed at reducing antibiotic dispensing at the practice level in primary care. DESIGN:Randomised controlled trial with general practices as the unit of randomisation and analysis. Clinicians and researchers were blinded ...

journal_title：BMJ (Clinical research ed.)

authors： Butler CC,Simpson SA,Dunstan F,Rollnick S,Cohen D,Gillespie D,Evans MR,Alam MF,Bekkers MJ,Evans J,Moore L,Howe R,Hayes J,Hare M,Hood K

更新日期：2012-02-02 00:00:00

abstract：OBJECTIVE: To compare the effectiveness of flexible sigmoidoscopy in screening for colorectal cancer by patient sex and age. DESIGN: Pooled analysis of randomised trials (the US Prostate, Lung, Colorectal and Ovarian cancer screening trial (PLCO), the Italian Screening for Colon and Rectum trial (SCORE), and the Norwe...

journal_title：BMJ (Clinical research ed.)

authors： Holme Ø,Schoen RE,Senore C,Segnan N,Hoff G,Løberg M,Bretthauer M,Adami HO,Kalager M

更新日期：2017-01-13 00:00:00

abstract：OBJECTIVES:To determine the relation between the HIV/AIDS epidemic and support for dependent elderly people in Africa. DESIGN:Retrospective analysis using data from Demographic and Health Surveys. SETTING:22 African countries between 1991 and 2006. PARTICIPANTS:123,176 individuals over the age of 60. MAIN OUTCOME M...

journal_title：BMJ (Clinical research ed.)

authors： Kautz T,Bendavid E,Bhattacharya J,Miller G

更新日期：2010-06-16 00:00:00

abstract：OBJECTIVE:To investigate the association between birth weight of offspring and mortality among fathers and mothers in the west of Scotland. DESIGN:Prospective observational study. PARTICIPANTS:794 married couples in Renfrew district of the west of Scotland. MAIN OUTCOME MEASURES:Mortality from all causes and from ca...

journal_title：BMJ (Clinical research ed.)

authors： Davey Smith G,Hart C,Ferrell C,Upton M,Hole D,Hawthorne V,Watt G

更新日期：1997-11-08 00:00:00

abstract：OBJECTIVE:To examine the associations of a vegetarian diet and dietary fibre intake with risk of diverticular disease. DESIGN:Prospective cohort study. SETTING:The EPIC-Oxford study, a cohort of mainly health conscious participants recruited from around the United Kingdom. PARTICIPANTS:47,033 men and women living in...

journal_title：BMJ (Clinical research ed.)

authors： Crowe FL,Appleby PN,Allen NE,Key TJ

更新日期：2011-07-19 00:00:00

abstract：OBJECTIVE:To cost the relation between socioeconomic status and various measures of primary care workload and assess the adequacy of current "deprivation" payments in relation to actual costings for patients living in qualifying areas. DESIGN:Retrospective data on primary care were collected over a 4.5 year period fro...

journal_title：BMJ (Clinical research ed.)

authors： Worrall A,Rea JN,Ben-Shlomo Y

更新日期：1997-01-04 00:00:00

abstract：OBJECTIVES:To identify the extent of HIV infection and injecting drug use among female streetworking prostitutes in Glasgow; to estimate the size of the female streetworking prostitute population in the city; and to estimate the number of HIV positive women working as prostitutes on the streets in Glasgow. DESIGN:Obse...

journal_title：BMJ (Clinical research ed.)

authors： McKeganey N,Barnard M,Leyland A,Coote I,Follet E

更新日期：1992-10-03 00:00:00

abstract：OBJECTIVES:To examine whether British South Asian children differ in insulin resistance, adiposity, and cardiovascular risk profile from white children. DESIGN:Cross sectional study. SETTING:Primary schools in 10 British towns. PARTICIPANTS:British children aged 8 to 11 years (227 South Asian and 3415 white); 73 Sou...

journal_title：BMJ (Clinical research ed.)

authors： Whincup PH,Gilg JA,Papacosta O,Seymour C,Miller GJ,Alberti KG,Cook DG

更新日期：2002-03-16 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of teaching general practitioners skills in brief cognitive behaviour therapy. DESIGN:Parallel group, cluster randomised, controlled trial of an educational package on cognitive behaviour therapy. SETTING:General practices in north London. PARTICIPANTS:84 general practitioner pr...

journal_title：BMJ (Clinical research ed.)

authors： King M,Davidson O,Taylor F,Haines A,Sharp D,Turner R

更新日期：2002-04-20 00:00:00

abstract：OBJECTIVES:To describe utilisation of general practitioners by elderly people resident in communal establishments; to examine variations in general practitioner utilisation and estimate the likely impact of the "downsizing" of long stay provision in NHS hospitals. DESIGN:Secondary analyses of the survey of disability ...

journal_title：BMJ (Clinical research ed.)

authors： Kavanagh S,Knapp M

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the immunogenicity and reactogenicity of a new triple S recombinant hepatitis B vaccine in a cohort of healthy people in whom currently licensed hepatitis B vaccines had persistently not induced an immune response. DESIGN:Single centre, randomised, double blind, dose-response study. SETTING:Rese...

journal_title：BMJ (Clinical research ed.)

authors： Zuckerman JN,Sabin C,Craig FM,Williams A,Zuckerman AJ

更新日期：1997-02-01 00:00:00

abstract：PROBLEM:Deep infection after joint arthroplasty can be catastrophic, leading to further surgery, loss of the prosthesis, disability, and risk of mortality. Twenty nine new cases of methicillin resistant Staphylococcus aureus occurred in the first year after elective orthopaedic surgery was centralised to a district gen...

journal_title：BMJ (Clinical research ed.)

authors： Biant LC,Teare EL,Williams WW,Tuite JD

更新日期：2004-07-17 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations. DESIGN:Prospective cohort study. SETTING:28 hospitals in the Netherlands and Belgium. PARTICIPANTS:1920 consecutive women treated with toc...

journal_title：BMJ (Clinical research ed.)

authors： de Heus R,Mol BW,Erwich JJ,van Geijn HP,Gyselaers WJ,Hanssens M,Härmark L,van Holsbeke CD,Duvekot JJ,Schobben FF,Wolf H,Visser GH

更新日期：2009-03-05 00:00:00

abstract：OBJECTIVE:To estimate the risk of acute myocardial infarction (AMI) or stroke in adults with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH). DESIGN:Matched cohort study. SETTING:Population based, electronic primary healthcare databases before 31 December 2015 from four European coun...

journal_title：BMJ (Clinical research ed.)

authors： Alexander M,Loomis AK,van der Lei J,Duarte-Salles T,Prieto-Alhambra D,Ansell D,Pasqua A,Lapi F,Rijnbeek P,Mosseveld M,Avillach P,Egger P,Dhalwani NN,Kendrick S,Celis-Morales C,Waterworth DM,Alazawi W,Sattar N

更新日期：2019-10-08 00:00:00

abstract：OBJECTIVE:To investigate the long term effects of continuous subcutaneous insulin infusion (insulin pump therapy) on cardiovascular diseases and mortality in people with type 1 diabetes. DESIGN:Observational study. SETTING:Swedish National Diabetes Register, Sweden 2005-12. PARTICIPANTS:18,168 people with type 1 dia...

journal_title：BMJ (Clinical research ed.)

authors： Steineck I,Cederholm J,Eliasson B,Rawshani A,Eeg-Olofsson K,Svensson AM,Zethelius B,Avdic T,Landin-Olsson M,Jendle J,Gudbjörnsdóttir S,Swedish National Diabetes Register.

更新日期：2015-06-22 00:00:00

abstract：BACKGROUND:Twenty-four hour ambulatory blood pressure thresholds have been defined for the diagnosis of mild hypertension but not for its treatment or for other blood pressure thresholds used in the diagnosis of moderate to severe hypertension. We aimed to derive age and sex related ambulatory blood pressure equivalent...

journal_title：BMJ (Clinical research ed.)

authors： Head GA,Mihailidou AS,Duggan KA,Beilin LJ,Berry N,Brown MA,Bune AJ,Cowley D,Chalmers JP,Howe PR,Hodgson J,Ludbrook J,Mangoni AA,McGrath BP,Nelson MR,Sharman JE,Stowasser M,Ambulatory Blood Pressure Working Group of the

更新日期：2010-04-14 00:00:00

abstract：OBJECTIVE:To examine the distribution of patterns of macronutrient density in relation to obesity. DESIGN:Cross sectional. SETTING:Denmark. SUBJECTS:323 men and women aged 35-65 years, selected randomly from a larger population sample of Danish adults. MAIN OUTCOME MEASURE:Bias in dietary reporting of energy and pr...

journal_title：BMJ (Clinical research ed.)

authors： Heitmann BL,Lissner L

更新日期：1995-10-14 00:00:00

abstract：:Two patients with acute major, disabling cerebral infarction with presumed middle cerebral artery occlusion were treated with the clot specific thrombolytic agent tissue plasminogen activator roughly three and a half hours after the onset of symptoms. Both patients had a normal computed tomography (CT) scan before tre...

journal_title：BMJ (Clinical research ed.)

authors： Koudstaal PJ,Stibbe J,Vermeulen M

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To study changes from 1969 to 1983 in the prognosis of patients with acute myocardial infarction treated in a coronary care unit. DESIGN:Mortality follow up of all patients with definite acute myocardial infarction. SETTING:The coronary care unit of the Royal Melbourne Hospital, a tertiary referral centre. ...

journal_title：BMJ (Clinical research ed.)

authors： Hopper JL,Pathik B,Hunt D,Chan WW

更新日期：1989-10-07 00:00:00

abstract：:About 70% of all abortions performed in Delhi, India, are terminations due to the fetus being female. Private clinics make a profit out of offering sex determination tests. The new bill (the Prenatal Diagnostic Techniques Bill) introduced in Lok Sabha by Deputy Health Minister Pawan Singh Ghatowatr would stop "sex d...

journal_title：BMJ (Clinical research ed.)

authors： Imam Z

更新日期：1994-08-13 00:00:00

abstract：OBJECTIVES:To measure the potential for cadaver organ retrieval in New South Wales and to determine the reasons for potential donors failing to become actual donors. DESIGN:Prospective audit of all patients dying in five hospitals in New South Wales between 1 December 1989 and 30 November 1990; quality assurance of th...

journal_title：BMJ (Clinical research ed.)

authors： Hibberd AD,Pearson IY,McCosker CJ,Chapman JR,Macdonald GJ,Thompson JF,O'Connell DL,Mohacsi PJ,McLoughlin MP,Spratt PM

更新日期：1992-05-23 00:00:00